Abstract: The invention provides a crystalline hydrochloride salt of (S)-3-[(S)-1-(4-chlorophenoxy)-2-methylpropyl]pyrrolidine. This invention also provides pharmaceutical compositions comprising the crystalline salt, processes and intermediates for preparing the crystalline salt, and methods of using the crystalline salt to treat diseases.

Abstract: A method and device for reusing materials and/or products by pulsed power according to which a series of electrical discharges are generated between at least two electrodes in a reactor containing an ambient liquid as well as the materials and/or products to be reused. The energy of the electric discharges, the voltage between the electrodes, the switching time and the frequency of the discharges are selected such that said discharges generate electric arcs that pass through the materials and/or products to be reused, and mechanical shock waves that propagate across the materials and/or products to be treated in the reactor. The result is fragmentation, pulverisation, dispersion and separation of the elements that make up the materials and/or products to be reused.

Abstract: Compounds of formula (I) are A2B receptor antagonists, wherein R1 is optionally substituted aryl or an optionally substituted 5- or 6-membered heteroaryl ring; R2 and R3 are independently selected from hydrogen, C1-C6 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-(C1-C6)-alkyl, aryl-(C1-C6)-alkyl optionally substituted in the ring part thereof, a 5- or 6-membered monocyclic heterocyclic group optionally linked via a C1-C6 alkylene chain and optionally substituted in the ring part thereof, benzimidazol-2-yl-methyl, pyrid-3-yl-carbonyl, or (1-methyl-piperidin-4-yl)-carbonyl-methyl; or R2 and R3 taken together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; R4 is C1-C3 alkyl, C2-C3 alkenyl, —N(—R5)—R6, or optionally substituted heteroarylmethylamino; and R5 and R6 are independently selected from hydrogen or C1-C3 alkyl; or R5 and R6 taken together with the nitrogen atom to which they are attached form an optionally substituted 4- to 6-membered saturated ring.

Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

Abstract: A method for reusing material by pulsed power, according to which a series of electrical discharges are generated between at least two electrodes in a reactor receiving an ambient liquid as well as the materials to be reused. The series of said electrical discharges produce, as a result of the energy, the frequency of the electrical discharges, the voltage between the electrodes and the switching time, a mechanical shockwave which propagates over the materials to be processed in the reactor. The ambient liquid is cooled by a continuous or carousel cooling system, to enable the production of nanoparticles.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: A mounting structure for an in-vehicle power battery may be provided. The mounting structure may comprise an upper cover (3), a suspension tray (1) and a bracket (2) for supporting at least a peripheral bottom portion of the suspension tray (1). The suspension tray (1) may be hermetically connected with the upper cover, forming a sealed space for receiving the power battery. The bracket (2) may be detachably fixed to a bottom surface of a body floor in a vehicle. Further, a vehicle (100) comprising the mounting structure described above is also provided.

Abstract: The present invention is drawn to a process of drilling organic glasses, comprising the steps of: (a) providing a substrate of organic glass, preferably of optical grade, (b) laminating onto at least one surface of said organic glass substrate via an adhesive layer selected from the group consisting of pressure sensitive adhesives and hot melt adhesives, a thermoplastic polymer film having a thickness of at least 40 ?m and an elastic modulus of at least 3 GPa, the peel strength of the thermoplastic polymer on the organic glass substrate being higher than 1.3 N/25 mm, preferably of at least 1.5N/25 mm, (c) drilling a hole through the substrate and polymer film by means of a drill, and (d) optionally removing the thermoplastic polymer film and adhesive.

Abstract: An ophthalmic lens holder (1), includes a pedestal (10) and at least three contact pads (30) that rise from the pedestal such as to have substantially coplanar free ends (31), whereby the contact pads are suitable for bearing the ophthalmic lens. The holder has at least three through-openings (25) of axes (A1) substantially orthogonal to the plane of the free ends of the three contact pads.

Abstract: A system and method for identifying an object includes a plurality of object sensors, each object sensor configured and arranged to determine at least one parameter describing objects as they are relatively moved with respect to a sensing volume and having a known position and attitude with respect to the sensing volume. A location sensor is configured and arranged to produce position information relating to the relative movement. Outputs from the object and location sensors are passed to a processor and the parameters are associated with respective ones of the objects on the basis of the position information and on the basis of the known positions and attitudes of the sensors. For each object having associated parameters, the processor compares the parameters to known item parameters to assign item identification to the object.

Abstract: Methods of compacting soil, and devices for carrying out the methods are provided in which an underground compacting device is inserted into the soil at a predetermined depth under which the compaction by the upper level of the soil becomes ineffective.

Abstract: A method for module-level processing of photovoltaic cells is provided. The method includes: bonding at least one crystalline silicon photovoltaic substrate to a carrier by means of an adhesive layer, thereby leaving part of the adhesive layer uncovered; after bonding, exposing the uncovered part of the adhesive layer and the at least one crystalline silicon photovoltaic substrate to a plasma; and removing a surface portion of the at least one crystalline photovoltaic substrate. The method may further include performing an annealing step of the adhesive before bonding the at least one photovoltaic substrate to the carrier, and performing an outgassing step of the adhesive after bonding the at least one photovoltaic substrate to the carrier. The method may further include module-level rear side processing of the at least one crystalline silicon photovoltaic substrate to make a photovoltaic module.

Abstract: Formulations of easily dispersible (ED) pigments comprising a combination of a carboxylic acid polymer and a non-ionic alkoxylated surfactant are disclosed. The combination is used in the formulation of a plurality of pigments. The formulations are suitable for mixing with a base medium at the point-of-sale (PoS) or by the end user.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: A self-retracting lifeline comprises a drum including first and second sides operatively connected to a base. A rotor includes a receiving portion and is operatively connected to the base. A pawl is pivotally operatively connected to the rotor, and a biasing member is positioned between the rotor and the pawl to place a biasing force upon the pawl. A bracket member includes a cavity and a stop member extending into the cavity. The cavity is configured and arranged to receive the drum, the rotor, the pawl, and the spring. The drum is rotatably operatively connected to the bracket member and the pawl is positioned proximate the stop member. The pawl and the biasing member are held in place by the first side of the base, the rotor, and the bracket member.

Abstract: A device receives a default cell handoff parameter set from a base station within a cellular network. The device receives a modified handoff parameter set, wherein the modified handoff parameter set is different than the default cell handoff parameter set, and tests a mobile device in different geographic locations served by the base station, using the modified handoff parameter set, to measure one or more network/call service parameters associated with handoff of the mobile device to a neighboring cell. The device identifies optimum modified handoff parameters for the mobile device based on the measured one or more network/call service parameters.

Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.

Abstract: The present invention provides a shear reinforcement for a reinforced concrete structure which may be installed within a reinforced concrete structure after the installation of reinforcing bars during construction, in order to increase resistance against shear failure. The shear reinforcement (10) for the reinforced concrete structure includes a reinforcement bracket (20) and a connecting bar (40), wherein the reinforcement bracket (20) is disposed in a fixed number along a lengthwise direction thereof, and the connecting bar (40) is parallelly disposed in a lengthwise direction of the connecting bar (40) and fixed on each of upper anchor heads (22) of a plurality of the reinforcement brackets (20). The shear reinforcement (10) for the reinforced concrete structure according to the present invention may maximize the shear reinforcing performance of a shear reinforcement proposed by this inventor through a prior application and improve the convenience of work.

Abstract: A new and distinct cultivar of Mandevilla plant named ‘Lannorthcarolina’, characterized by its upright and twining plant habit; moderately vigorous to vigorous growth habit; large glossy dark green-colored leaves; and large pink-colored flowers.