Abstract: The present invention provides a screening method for determining whether a substance of interest is a substance which alters GPR120 mediated cell stimulating activities, comprising using a substance of interest, a biomembrane containing GPR120, or cells containing said biomembrane, and phospholipase or salts thereof. According to a screening method of the present invention, the method can screen substances such as CCK and GLP-1 which are involved in the secretion of hormones in gastrointestinal tracts.
Abstract: A method for managing user context by a Home evolved NodeB (HeNB) is provided. The method includes requesting, by a Mobility Management Entity (MME), the HeNB to reserve a first type of User Equipment (UE) context information, obtaining, by the HeNB, the MME of the UE according to the first type of UE context information after receiving data, and notifying, by the HeNB, the MME of an arrival of the data. With the method according to the present invention, it is guaranteed by an HeNB system that a terminal can receive downlink signaling after activation of a local routing optimization service by the terminal.
Type:
Application
Filed:
September 11, 2009
Publication date:
July 28, 2011
Applicants:
SAMSUNG ELECTRONICS CO., LTD., BEIJING SAMSUNG TELECOM R&D CENTER
Inventors:
Huarui Liang, Tae-sun Yeoum, Xiaoqiang Li
Abstract: The present invention provides benzoxazole compounds and pharmaceutically acceptable salts thereof and pharmaceutical compositions including the same. The present invention further provides methods of use as described herein.
Type:
Application
Filed:
September 25, 2009
Publication date:
July 28, 2011
Applicant:
EISAI R&D MANAGEMENT CO., LTD.
Inventors:
Wanjun Zheng, Mark Spyvee, Fabian Gusovsky, Sally T. Ishizaka
Abstract: A bolt (20, 20?) for locking the stock (11) to a receiver (12) of a firearm having mobile masses (13), comprising a tubular element (21) which can be closed at the ends respectively by means of a bolt-body cap (22) which can be screwed to the receiver (12) and by means of a bolt -stock cap (23) on which the stock (11) can be tightened, the tubular element housing in its interior a mechanism (40, 40?) for damping the withdrawal speed of the mobile masses (13) of the firearm, situated on their withdrawal trajectory and equipped with a free end not connected to the mobile masses (13) and destined for coming into contact with the latter during their withdrawal movement following the firing of the firearm for damping the stress.
Abstract: A process for preparing frozen particles having an average diameter of from 1 to 10 mm and comprising from 1 to 50 wt % of a frozen aqueous core and from 50 to 99 wt % of a fat-based shell is provided, the process comprising: providing a dispensing device having an inner nozzle and an outer nozzle which surrounds the inner nozzle; supplying an aqueous mix to the inner nozzle and a fat-based mix to the outer nozzle, thereby forming particles with a water-continuous core and a fat-continuous shell, and then dropping the particles into a refrigerant.
Type:
Application
Filed:
January 20, 2011
Publication date:
July 28, 2011
Applicant:
CONOPCO, INC., D/B/A UNILEVER
Inventors:
Ian William Burns, Andrea Williams, Shiping Zhu
Abstract: An optical detection system for identifying target bacterial cells in a food sample, comprising a first fluorescent nanoparticle dye labeling specifically the target cells. A second fluorescent dye reacts non-specifically with all bacterial cells. An imaging unit optically excites the fluorescent dyes and captures images of the sample for each of two different wavelength bands emitted as a result of the excitation of the dyes. A processing unit identifies the target cells from the sample and comprises an image processing unit for processing the images of the sample. A target cell identifier identifies the target cells in the images by detecting individual units present at a same location in both of the processed images. An output unit provides data related to the identified target cells in the sample. A method is also provided.
Type:
Application
Filed:
January 21, 2011
Publication date:
July 28, 2011
Applicant:
INSTITUT NATIONAL D'OPTIQUE
Inventors:
Isabelle NOISEUX, Pascal GALLANT, Ozzy MERMUT, Marcia VERNON
Abstract: A container is provided for storing and dispensing consumer products including pills, tablets, or capsules. A multi-cavity container is also provided for organizing and storing mixed medication for subsequent dispensation according to predefined dosage regimen. The container can comprise a tray (1) having a generally planar top surface (2) into which has been formed one or more discrete cavities (30) for receiving the consumer products. A sheet (10) can be adhered to top surface (2) using a peelable adhesive to seal discrete cavities (30). Sheet (10) can comprise pre-formed lines of separation (13) defining a closure portion (12) for each cavity, which retains the consumer products in that cavity until the closure portion is removed by separation along its lines of separation. Each closure portion (12) can have low vapor transmission properties created by a patch (24) having high vapor barrier properties.
Abstract: The invention relates to a honeycomb structure, made from a porous ceramic material, said structure being characterized in that the porous ceramic material which forms it comprises: from 50 to 95% by weight of silicon carbide SiC; from 5 to 50% by weight of at least one ceramic oxide phase, said structure additionally being characterized by a porosity greater than 10%, by a specific surface area greater than 0.5 m2/g and by a pore size distribution of at least bimodal type. The invention also relates to the process for obtaining such a structure and also to the catalytic support or filter obtained from such a structure, after deposition of a catalyst.
Type:
Grant
Filed:
July 19, 2006
Date of Patent:
July 26, 2011
Assignee:
Saint-Gobain Centre de Recherches et d'Etudes Europeen
Inventors:
Carine Barataud-Dien, Patricia Andy, Sebastien Bardon, Anthony Briot
Abstract: A novel class or family of TGF-? binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and methods for utilizing such molecules. In particular, compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures.
Type:
Grant
Filed:
July 16, 2009
Date of Patent:
July 26, 2011
Assignee:
Celltech R & D, Inc.
Inventors:
David G. Winkler, John Latham, Jiye Shi
Abstract: The invention relates to compounds of formula I: along with pharmaceutical compositions containing the same and methods of use thereof for the treatment of autoimmune disease.
Type:
Grant
Filed:
May 24, 2007
Date of Patent:
July 26, 2011
Assignee:
Eisai R&D Management Co., Ltd.
Inventors:
Francis Fang, Shawn Schiller, Boris Seletsky, Mark Spyvee
Abstract: An implantable device (1) for injecting fluid and/or for tapping fluid, the device having a housing (3) provided with a puncture zone (4) able to be transpierced by a hollow needle (5) for injecting fluid into and/or tapping fluid from a chamber (3A) provided inside the housing (3). The implantable device has a puncture zone (4) made up of at least first and second superposed flexible membranes (6, 7) mounted to be free, at least locally, relative to each other, to allow the membranes, at least locally, to move along each other, so that, once the needle (5) has been removed, the orifice formed by the needle (5) is sliced into first and second sub-orifices (6A, 7A) substantially not coinciding so as to impart a substantially leaktight property to the puncture zone (4).
Type:
Grant
Filed:
November 4, 2005
Date of Patent:
July 26, 2011
Assignee:
Compagnie Europeenne d'Etude et de Recherche de Dispositifs pour l'Implantation par Laparoscopie
Abstract: A device includes at least one built-in flexible portion (1) between two stiffer portions (10) that are made of a stiff composite material, the flexible portion (11) being suitable for forming a flexible hinge and made of a flexible material including a reinforcing armature that includes at least one connecting layer (13) common to the material(s) forming each stiff portion (10). The device has end surfaces (20) that oppose each other when extended, the opposing end surfaces being arranged to be suited to serve as a longitudinal compression abutment while enabling the thus-made hinge to fold back at least in a direction away from the extended state.
Type:
Application
Filed:
September 24, 2009
Publication date:
July 21, 2011
Applicant:
CENTRE NATIONAL D'ETUDES SPATIALES (CNES)
Abstract: In one aspect, the present invention relates to compounds of Formula (I): to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to method for their preparation.
Type:
Application
Filed:
July 16, 2008
Publication date:
July 21, 2011
Applicant:
ASTRAZENECA R&D
Inventors:
Gregory Steven Basarab, Jacques Dumas, Pamela Hill
Abstract: The invention relates to a structure of the honeycomb type, comprising a porous ceramic material based on aluminum titanate, the thermal expansion coefficient of which between 20 and 1000° C. is less than 2.5×10?6/° C., said structure also having a porosity greater than 10% and a pore size centered between 5 and 60 microns, said structure being characterized in that the composition of the porous ceramic material comprises, by weight, from 30 to 60% of Al2O3, from 30 to 60% of TiO2, from 1 to 20% of SiO2, less than 10% of MgO, less than 0.5% of oxides from the group Na2O, K2O, SrO, CaO, Fe2O3, BaO and rare earth oxides, said structure also being characterized in that it has a permanent linear change on reheating, after heating at 1500° C., of less than ±0.3%. The invention also relates to a catalytic filter or support obtained from such a structure.
Type:
Application
Filed:
May 28, 2009
Publication date:
July 21, 2011
Applicant:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUR
Abstract: A series of progressive ophthalmic lenses is proposed, which is indexed by optical power addition values of eyeglasses of spectacles to be made from these lenses. Each lens of the series determines a further gap between a value of the optical power for the near vision direction and a maximum value of the optical power which is obtained for a direction of gaze pointing below said near vision direction. The lenses of the series are adapted for postures of wearers that may vary as a function of the optical power addition values.
Type:
Application
Filed:
March 2, 2009
Publication date:
July 21, 2011
Applicant:
Essilor International (compagnie Generale D'optiqu e)
Abstract: The present invention relates a weaving torch device for auto welding that can maintain necessary molten metal for desired welding such as welding by a person and provide the best welding beads, by locking a hinge pin and a conveying pin, which are provided to both sides of a weaving torch of a torch device connected to a welding machine, to a locking protrusion and a locking step of a hinge support member of a lower case in order to prevent left/right conveying while the weaving torch is automatically reciprocated up/down by operation of an electromagnet and a conveying spring.
Abstract: A portable, non-power operated cutting tool for cutting sheets of building materials in a straight fashion without splintering or cracking. The cutting tool includes a base, a blade holder with a blade, and a handle with an eccentric cam rotatably connected to the base, where the blade holder moves between an open position and a closed position by rotating the eccentric cam.
Abstract: A pump having an undulating diaphragm mounted for undulating between two end plates under drive from at least one electromagnetic actuator in order to transfer a fluid between an inlet of the pump and an outlet of the pump. The pump includes adapter means connecting the diaphragm support to a movable portion of the actuator in order to shorten the stroke of the movable mass of the actuator such that its stroke is shorter than the stroke of the diaphragm support.