Abstract: Methods and systems for preparing alkylene glycols are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of alkylene oxides with water. The high shear device may allow for lower reaction temperatures and pressures and may also reduce reaction time.

Abstract: 65B13 was discovered to be a useful marker for isolating GABA neuron progenitor cells including Purkinje cells. Furthermore, E-cadherin was revealed to be a useful marker for isolating Purkinje progenitor cells from a 65B13-positive cell population. Specifically, when used in combination with 65B13, E-cadherin was found to be a useful marker for isolating Purkinje progenitor cells.

Abstract: Methods and systems for the hydrogenation of aldehydes and/or ketones are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of the hydrogen-containing gas (e.g. H2 gas) in the aldehydes and/or ketones. The high shear device may allow for lower reaction temperatures and pressures and may also reduce hydrogenation time with existing catalysts.

Abstract: An actuation system for at least two mobile elements with dynamically compensated and opposite relative motions, without disturbance of the elements fixed in the same rigid structure as it, and resistant to exterior loadings, in the case of a translational motion of the mobile elements, includes, in a rigid structure, at least one linear actuator linked to a motion transmission device with four rigid arms, articulated at their ends and forming a lozenge, of which each of two first opposite vertices is linked to a corresponding mobile element, and whose other two opposite vertices have a single translational degree of freedom.

Abstract: The present invention relates to Penta-hexa-, hepta-, octa-, nona- and, deca-heteroaryl derivatives, comprising a combination of heterocycle 1 (Het-1)a and/or heterocycle 2 (Het-2)b and/or heterocycle 3 (Het-3)c and/or heterocycle 4 (Het-4)d of formulae I, II, III and IV respectively, the N-oxides, the pharmaceutically acceptable addition salts. The compounds claimed are suitable for the treatment of cancer.

Abstract: The invention relates to a liquid heating device for an automobile that comprises two independent liquid flow paths (10a, 10b) integrally formed in at least one part (1a) made of a heat-conducting material, each liquid flow path (10a) being capable of enabling a flow of liquid between a connection terminal defining an inlet and a connection terminal defining an outlet (12a, 12b), each of the connection terminals being capable of sealingly receiving a liquid supply duct or tube, and a heating means (14) thermally coupled with said part (1a) and capable of heating said part (1a) so that the liquid flowing through said flow paths can absorb the heat of said part (1a). The invention advantageously enables the very flexible use thereof for one or more systems requiring heated liquid inside a single vehicle.

Abstract: Sports stations are provided, a representative version of which includes multiple vertical and horizontal posts interconnected to define multiple sport regions, with the multiple sport regions being configured to permit simultaneous play of different sports. At least first and second of the multiple sport regions are displaced vertically with respect to each other, and at least a third of the multiple sport regions is displaced horizontally with respect to the first and the second of the multiple sport regions.

Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.

Abstract: A method of treating esophageal cancer, containing the step of administering to a patient suffering from esophageal cancer, a compound or a salt thereof, wherein the compound is: N-(2-fluoro-4-{[2-({[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N?-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, N-[4-({2-[(azetidin-1-ylcarbonyl)amino]pyridin-4-yl}oxy)-2-fluorophenyl]-N?-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, N-{2,5-difluoro-4-[(2-{[(3-hydroxyazetidin-1-yl)carbonyl]amino}pyridin-4-yl)oxy]phenyl}-N?-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, N-(2,5-difluoro-4-{[2-({[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N?-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, N-(2,5-difluoro-4-{[2-({[methyl(1-methyl-piperidin-4-yl)amino]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N?-(4-fluorophenyl)-cyclopropane-1,1-dicarboxamide, or N-(2,5-difluoro-4-{[2-({[3-(hydroxymethyl)azetidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N?-(4-fluorophenyl)

Abstract: A method for determining by optimization a set of progressive ophthalmic lenses for a given user for whom a near vision power addition (Addn) has been prescribed includes the following steps: measuring the user's near vision individual physiological parameters; determining an ergorama associating, on each lens, a target point in each look direction in worn conditions; determining a target power defect and a resulting target astigmatism for each direction of look under worn conditions, the target power defect and the resulting target astigmatism being determined from the user's measured physiological parameters; computing the power required for each lens for said ergorama by successive iterations to reach the target power defect and the target astigmatism for each look direction.

Abstract: A spread spectrum method for a digital input signal (x(n)), comprising the following steps: coefficients of a reversible digital periodical linear filter are selected in such a way that the spectrum of the input signal (x(n)) is spread in order to occupy a spread frequency band (B) with the exception of at least one eliminated frequency sub-band (B?), included in a spread frequency band, and the input signal is processed via the digital periodical linear filter in such a way as to obtain a spread spectrum output signal (y(n)).

Abstract: The invention relates to a structure for filtering particle-laden gases, comprising an assembly of elements of the honeycomb type linked by a joint or seal, each element incorporating a set of adjacent ducts or channels 20 of mutually parallel axes and separated by porous walls, which ducts are closed off by plugs at one or other of their ends so as to define entry chambers that open onto a gas intake face and exit chambers opening onto a gas discharge face 25, in such a way that the gas to be filtered passes through the porous walls, said structure being characterized in that its geometrical centre, in a cross section of the structure perpendicular to its main axis, does not correspond to a symmetry element of an element or of a group of elements 30 in the assembly.

Abstract: A process for edging an optical lens for conforming the optical lens to the size and shape of a lens frame into which the optical lens is to be accommodated, said process comprising: a) providing an optical lens having a convex surface, the convex surface being provided with an anti-smudge topcoat rendering the optical lens inappropriate for edging; b) fixing a mounting element on the convex surface of the optical lens, preferably on its center, by means of an adhesive pad adhering both to the mounting element and the convex surface of the optical lens to form a mounting element/optical lens assembly; c) placing the mounting element/optical lens assembly in a grinding machine so that the optical lens is firmly maintained; and d) edging the optical lens to the intended size and shape, wherein, prior to step (b) of fixing the mounting element, the anti-smudge topcoat on the convex surface of the optical lens is pre-treated with a solvent selected from the group consisting of alkanols and dialkylketones under a

Abstract: A method for evaluating electrocardiogram QT interval-prolonging action of a test substance, which comprises preparing a hamster anesthetized under such a condition that end of T wave is definitely observed on an electrocardiogram, and comparing electrocardiogram QT intervals of the hamster observed before and after administration of the test substance to evaluate electrocardiogram QT interval-prolonging action of the test substance.

Abstract: A system and method for associating and controlling multimedia supporting events with a primary event. The events are translated into tasks and sent to media servers for execution at a predetermined time by being further translated into media specific tasks to control a bit-pump.

Abstract: The invention relates to diazaindole derivatives represented by the general formula (I): where A, E, G, R1, R2, R3 and R4 are defined herein, or pharmaceutically acceptable salts thereof, their use in the inhibition of c-Jun N-terminal kinase (JNK) activity, their use in medicine and particularly in the treatment of neurodegenerative disorders, inflammatory diseases, autoimmune diseases and/or organ failure. The invention also provides processes for the manufacture of said diazaindole derivatives and compositions containing them.

Abstract: A magnetic read device including: a magnetic read head including a first conductive winding; and a second conductive winding connected in phase opposition to the first winding.

Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA wither alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Abstract: There is provided a cyanoacrylate composition comprising: a cyanoacrylate; and a 2-substituted benzothiazole or a derivative thereof wherein the 2-substituent is an alkyl, an alkene, an alkylbenzyl, an alkylamino, an alkoxy, an alkylhydroxy, an ether, a sulfenamide, a thioalkyl or a thioalkoxy group, with the proviso that an amide portion of the sulfenamide does not have a tert butylamino or a morpholine group.

Abstract: A new and distinct variety of cactus pear having the following unique combination of desirable features: 1. A fruit with a yellow/orange colored edible interior portion. 2. An average Brix of 13.1% 3. An average firmness of the pulp of 3.1 lb 4. An average pulp percentage of 55%. 5. A fruit weight ranging from 140 to 220 g. 6. Cladodes that have a low percentage of areoles with spines and those areoles only have 1 spine per areole of maximum length of 10 mm.