Patents Assigned to D
  • Nitrogen containing heterocyclic compounds and medicines containing the same
    Patent number: 7915274
    Abstract: Compounds represented by the following general formula: [wherein X1, X2, X3 and X4 each independently represent a single bond, C1-6 alkylene, etc.; A2 represents optionally substituted phenyl, etc.; A1 represents an optionally substituted 5- to 7-membered heterocyclic group containing —C(=Q1)- (wherein Q1 represents oxygen, sulfur or ?N—R11 (wherein R11 represents hydrogen or C1-6 alkyl)) and nitrogen, etc.; and Z1 represents piperidin-diyl, etc.], salts thereof and hydrates of the foregoing.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: March 29, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Fumihiro Ozaki, Mutsuko Ono, Koki Kawano, Yoshihiko Norimine, Tatsuhiro Onogi, Takashi Yoshinaga, Kiyoaki Kobayashi, Hiroyuki Suzuki, Hiroe Minami, Kohei Sawada
  • Lock attachment for audio-visual connector
    Patent number: 7914316
    Abstract: The combination of an electronic connector plug and an attached locking clip, wherein the connector comprises a cable, a plug housing surrounding one end of the cable, and a plug supported in the housing, such that the plug extends from the front of the housing and is electrically connected through the housing to the cable. The clip surrounds the housing and can be locked onto an electrical component by a lock screw such that the advancing screw also urges a clamp against the housing thereby securing the plug into the jack of the component. The electrical component is preferably an audio-visual (AV) device having an HDMI socket.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: March 29, 2011
    Assignee: D'Addario & Company, Inc.
    Inventors: James D'Addario, Robert O. Miller
  • Immunomodulatory compounds and methods of use thereof
    Patent number: 7915238
    Abstract: The present invention is directed to methods of treating diseases and disorders related to immune responses by administering one or more immunomodulatory compounds. In particular, the invention is directed to methods of stimulating and reducing immune responses, therapeutic and prophylactic treatment of cancer, treating autoimmune conditions, treating allergic reactions and asthma, and preventing ischemic damage and asthma by administering one or more immunomodulatory compounds.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: March 29, 2011
    Assignee: Eisai R & D Management Co., Ltd.
    Inventors: Lynn D. Hawkins, Sally T. Ishizaka
  • Data stream recovery
    Patent number: 7916754
    Abstract: A method and processor for recovering a plurality of individual data streams from a composite data stream The composite data stream having been formed by first bit reordering the individual data streams with respect to themselves, combining the individual data streams and second bit reordering the combined individual data streams to form the composite data stream. The processor is arranged to for a current bit position in the composite data stream perform the steps of: (a) applying an inverse of the second bit reordering; (b) identifying to which individual data stream the current bit belongs; (c) storing the current bit in a memory space allocated to the identified individual data stream wherein the current bit is positioned within the memory space according to the first bit reordering; and performing steps (a) to (c) for each bit position in the composite data stream.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: March 29, 2011
    Assignees: MStar Semiconductor, Inc., MStar Software R&D, Ltd., MStar France SAS, MStar Semiconductor, Inc.
    Inventor: Cyril Gregoire Fabrice Valadon
  • Vacuum anchor
    Patent number: 7914057
    Abstract: In one aspect of the invention, a vacuum anchor assembly for anchoring a fall protection system to a surface of an anchorage structure comprises an anchor member having an air input connector, a venturi, and a seal member incorporated into the anchor member. The air input connector is configured and arranged to receive air from a pressurized air source. The venturi is in fluid communication with the air input connector and is configured and arranged to receive air and create a vacuum therefrom. The seal member is in fluid communication with the venturi and is configured and arranged to receive the vacuum and resulting suction and create a seal between the anchor member and the surface of the anchorage structure sufficient to operatively connect the anchor member to the surface of the anchorage structure with the vacuum and resulting suction created within the anchor member.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: March 29, 2011
    Assignee: D B Industries, Inc.
    Inventor: Bradley A. Rohlf
  • METHOD FOR OBTAINING A SEQUOYITOL-CONTAINING EXTRACT FROM GENUS NEPHROLEPIS AND USES THEREOF
    Publication number: 20110071225
    Abstract: A method for obtaining a sequoyitol-containing extract from a plant of genus Nephrolepis, comprising extracting with a solvent, recovering the solvent to give an extractum, subjecting the extractum to two-phase extraction and column chromatography, collecting the fractions containing sequoyitol, concentrating, filtration and drying. The main active ingredient of the extract obtained is sequoyitol, which can be used for treating diabetes and its complications.
    Type: Application
    Filed: May 19, 2008
    Publication date: March 24, 2011
    Applicant: GUANGZHOU WELMAN NEW DRUG R&D CO., LTD.
    Inventors: Tianyu Sun, Yanli Wang, Yinyin Wang, You Lu, Ting Wang
  • Methods for Identifying Genomic Deletions
    Publication number: 20110070588
    Abstract: The genomic locus responsible for Van Buchem's disease is narrowed to an approximately 92 kb region of human chromosome 17 at 17q21. Individuals afflicted with or carriers of Van Buchem's disease exhibit a 52 kb deletion within this 92 kb region. Methods are provided that permit the differentiation between individuals homozygous for and therefore afflicted with Van Buchem's disease, individuals heterozygous for and therefore carriers of Van Buchem's disease, and individuals who are normal with respect to Van Buchem's disease. Also provided are general methodologies for the detection of a wide variety of large genomic deletions.
    Type: Application
    Filed: August 27, 2010
    Publication date: March 24, 2011
    Applicant: Celltech R&D Inc.
    Inventors: Mary E. BRUNKOW, Sean PROLL, Bryan W. PAEPER, Karen STAEHLING-HAMPTON
  • METHOD FOR HOLDING A LENS FOR DIP TREATMENT THEREOF
    Publication number: 20110070364
    Abstract: Method for dip treatment of an optical element, wherein the optical element is held, while it is being dipped, by a holding ring, the ring including a hoop for draining and encircling a peripheral edge of the optical element, thereby exerting continuous linear contact with the peripheral edge, the hoop forming an arc over more than 180° and being provided at each of its two ends with an outwardly-directed drip tab pointing away from the optical element.
    Type: Application
    Filed: November 30, 2010
    Publication date: March 24, 2011
    Applicant: ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE)
    Inventors: Pierre CARON, Annette Cretier, Annick Gascons
  • Method of Fabricating an Electric Insulator With a Polymer Housing Containing Antiozonants
    Publication number: 20110071242
    Abstract: A method of fabricating a composite insulator with a protective housing made of a polymer material incorporating an antioxidant and an antiozonant includes the step consisting in incorporating said antiozonant at a final concentration by weight lying in the range 0.005% to 1%, and said antioxidant at a final concentration by weight lying in the range 0.005% to 1%, said antiozonant being selected from the family of phenylenediamines, and said antioxidant being selected from the family of multifunctional phenolic antioxidants.
    Type: Application
    Filed: February 13, 2009
    Publication date: March 24, 2011
    Applicant: SEDIVER SOCIETE EUROPEENNE D'ISOLATEURS EN VERRE ET COMPOSITE
    Inventor: Guy Thevenet
  • METHOD AND APPARATUS FOR PROVIDING DIFFERENTIAL PROTECTION FOR AN ELECTRICAL LINK IN A MEDIUM, HIGH, OR VERY HIGH VOLTAGE NETWORK
    Publication number: 20110069421
    Abstract: A method and a differential protection apparatus for an electrical link in a medium, high or very high voltage power distribution network. This method, in which two differential protection devices are disposed at the two ends (A, B) of said link, includes a step during which a comparison is made between the current measured locally and the current measured remotely, after said devices have been resynchronized by phase shifting the data received from the end situated remotely by one half of the sum of the outward and return propagation times; and a second step during which, if an angular phase difference is found to exist between two currents after resynchronization, automatic compensation is effected by servocontrolling the angle of the current vectors.
    Type: Application
    Filed: May 29, 2009
    Publication date: March 24, 2011
    Applicant: AREVA T & D PROTECTION & CONTROLE
    Inventor: Jean Marmonier
  • VEHICLE DOOR LOCK WITH INSIDE RELEASE LEVER
    Publication number: 20110068586
    Abstract: The invention relates to a vehicle door lock having a rotary latch arrangement for locking doors of motor vehicles, in particular for tractors, having two rotatably mounted rotary latches, wherein for each rotary latch, provision is made of in each case one locking element which interacts therewith, which locking elements can interact with the rotary latches so as to lock the lock, and also having an actuating lever (35) by means of which the locking elements can be actuated so as to release the locking action, wherein the actuating lever (35) can be actuated from a first side of the lock (1) by being pressed, wherein the vehicle door lock (1) has an inside release lever (51) which can be actuated directly from an opposite side by being pressed, and wherein the actuating lever (35) can be driven by means of the inside release lever (51).
    Type: Application
    Filed: April 14, 2009
    Publication date: March 24, 2011
    Applicant: D. LA PORTE SOEHNE GMBH
    Inventors: Horst Kutschat, Yvonne Haehnke
  • GUIDEWIRE-STYLE PACING LEAD
    Publication number: 20110071608
    Abstract: The present invention relates generally to implantable pacing leads, and more particularly to guidewire-styled temporary transvenous endocardial leads for pacing or other medical applications.
    Type: Application
    Filed: September 22, 2010
    Publication date: March 24, 2011
    Applicant: Lake Region Manufacturing, Inc. d/b/a Lake Region Medical
    Inventors: Mark G. Fleischhacker, Joseph F. Fleischhacker
  • NON-ELECTROLYTIC DEPOSITION METHOD
    Publication number: 20110070361
    Abstract: The invention relates to a method for the non-electrolytic deposition of a compound, preferably an electrochromic compound, comprising the following successive steps: (a) an electroconductive layer is deposited on a non-conductive solid substrate; (b) a reducing agent or an oxidizing agent (=redox agent) is deposited on an area of said electroconductive layer, said area covering only a portion of the surface of said electroconductive layer; and (c) a solution of a precursor of the compound to be deposited is brought into contact both with the redox agent and with at least a portion of the area of said electroconductive layer not covered by the redox agent, said precursor being chosen from those having an oxidation-reduction potential higher or lower than the redox agent and forming, after an oxidation-reduction reaction, a compound insoluble in the solution of the precursor of the compound to be deposited.
    Type: Application
    Filed: June 23, 2009
    Publication date: March 24, 2011
    Applicant: Essilor International (compagnie Generale D'optiqu
    Inventors: Sandrine Duluard, Claudine Biver
  • STREAMING MEDIA ENCODER WITH FRONT PANEL CONTROL INTERFACE
    Publication number: 20110072149
    Abstract: A streaming media encoder for encoding and delivering media content is disclosed. The streaming media encoder has a media input interface for receiving a media stream, a media encoder for receiving the media stream from the input interface and encoding the media stream, thereby producing an encoded media stream. The media encoder has a first confidence monitor for displaying a video image from the received media stream, a second confidence monitor for displaying a video image from the encoded media stream, and a network interface for providing the encoded media stream to a network.
    Type: Application
    Filed: October 19, 2010
    Publication date: March 24, 2011
    Applicant: VIEWCAST.COM, INC. D/B/A VIEWCAST CORPORATION
    Inventors: MARK HERSHEY, DAVID T. STONER, RICK SOUTHERLAND
  • Gene Expression Profiling for Predicting the Response to Immunotherapy and/or the Survivability of Melanoma Subjects
    Publication number: 20110070582
    Abstract: A method is provided in various embodiments for determining a profile data set for predicting the response top immunotherapy and or survivability of a subject with melanoma based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification under measurement conditions that are substantially repeatable for measuring the amount of RNA corresponding to at least 2, 3 or 4 constituents according to the gene models shown in Tables 2-3, 4-6 and 9.
    Type: Application
    Filed: June 2, 2010
    Publication date: March 24, 2011
    Applicant: Source Precision Medicine, Inc. d/b/d Source MDX
    Inventors: Danute M. Bankaitis-Davis, Lisa Siconolfi, Kathleen Storm, Karl Wassmann
  • Reporter vector for use in evaluation of CYP1A2 induction
    Patent number: 7910362
    Abstract: A reporter vector which can evaluate the ability of a drug to induce CYP1A2 or both of CYP1A1 and CYP1A2 and a method for evaluation of the ability of a drug to induce CYP1A2 or both of CYP1A1 and CYP1A2 by using the reporter vector. A reporter system which can evaluate the ability of a drug capable of inducing CYP1A2 or both of CYP1A1 and CYP1A2 is completed by constructing a reporter vector having a reporter gene linked to the 3? end of a region between CYP1A1 and CYP1A2 or a reporter vector having different reporter genes linked to the both ends of the region, respectively, so as to sandwich the region, and a reporter vector having a deletion mutation in the region, and confirming that the expression of a reporter molecule is increased by the drug capable of inducing CYP1A2 or both of CYP1A1 and CYP1A2 in the reporter system using the reporter vector.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: March 22, 2011
    Assignees: Eisai R&D Management Co., Ltd., Tohoku University
    Inventors: Rika Ueda, Kazutomi Kusano, Yasushi Yamazoe, Kiyoshi Nagata
  • Method of screening for compounds which affect the processing of EphA4 by ?-secretase
    Patent number: 7910324
    Abstract: The present invention provides a method of screening for compounds which affect the processing of EphA4 by ?-secretase, which includes the following steps: (i) contacting a first biological composition containing ?-secretase or a biologically active fragment thereof with a second biological composition containing EphA4 in the presence and absence of a candidate compound; (ii) measuring the cleavage of the EphA4 in the presence and absence of the candidate compound; (iii) selecting those candidate compounds which affect the cleavage of the EphA4 by ?-secretase; and (iv) identifying the candidate compounds selected in step (iii) as compounds which affect the processing of EphA4 by ?-secretase.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: March 22, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventor: Eiji Inoue
  • Zirconium-base sintered product
    Patent number: 7910508
    Abstract: The inventive sintered product is produced from an initial feedstock having a zirconium content ranging from 75 to 99% and the following average chemical weight composition, in percentage by weight, based on oxides: 60%=ZrO2+HfO2=75%, 27%=SiO2=34%, 0.2=TiO2=1.5 %, 0.3<Y2O3=3.5 %, other oxides: =1%, to give a total of 100%. Said product can be used for glassworks.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: March 22, 2011
    Assignee: Saint-Gobain Centre de Recherches et d'Etudes European
    Inventors: Michel Gaubil, Yves Boussant-Roux, Charles McGarry, Isabelle Cabodi, Olivier Citti
  • Crystal and salt of 1-cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine
    Patent number: 7910734
    Abstract: Salts and crystals of 1-cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine have excellent cell adhesion inhibitory action and cell infiltration inhibitory action, and are useful as therapeutic or prophylactic agents for various inflammatory diseases and autoimmune diseases associated with adhesion and infiltration of leukocytes, such as inflammatory bowel disease (particularly ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma and atopic dermatitis.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: March 22, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Makoto Kotake, Naoki Yoneda, Katsunobu Osada
  • Fungal cell wall synthesis gene
    Patent number: 7910712
    Abstract: The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: March 22, 2011
    Assignee: Eisai R&D Management Co., Ltd
    Inventors: Kappei Tsukahara, Katsura Hata, Koji Sagane, Kazutaka Nakamoto, Mamiko Tsuchiya, Naoaki Watanabe, Fuminori Ohba, Itaru Tsukada, Norihiro Ueda, Keigo Tanaka, Junko Kai