Abstract: A method for regulating plant architecture includes applying a composition containing ?-Aminobutyric acid (GABA), glutamic acid and choline chloride to a plant. The composition for regulating plant architecture is also provided.
Type:
Grant
Filed:
June 7, 2021
Date of Patent:
January 17, 2023
Assignee:
CH BIOTECH R&D CO., LTD.
Inventors:
Yu-Lun Liu, Cho-Chun Huang, Gui-Jun Li, Kai Xia
Abstract: The device for covering a rail of a vehicle seat comprises a cover strip for the rail and a guide support for guiding the sliding of the cover strip above the rail, the at least one guide support supporting the cover strip on side of said strip.
Abstract: A method for disconnecting a wireless time-division duplex communication link. The time-division duplex communication link being between a first node transmitting during time slots allocated to said first node, wherein a second node is transmitting during separate time slots allocated to said second node, said first node transmitting at a respective one of a plurality of frequency bands during each of said time slots allocated to said first node.
Abstract: A method for controlling a brushless and sensorless, direct current electric motor (3) for motor vehicle equipment, wherein the electric motor (3) comprises a rotor and phases (A, B, C) powered by a pulse width modulation applied to a power inverter (1) of the electric motor (3), and wherein, beyond a minimum threshold (Smin) of the rotation speed of the rotor, the position of the rotor is determined from a measurement of electromotive forces at the phases (A, B, C) of the electric motor (3), said control method is characterised in that, in the event of a command (104) to stop the electric motor (3), the speed of rotation of the rotor is reduced (105) from a nominal speed to a predetermined rotation speed (V1) within a range between the minimum threshold (Smin) and 10% above said minimum threshold (Smin) by modifying the pulse width modulation, then the electric motor (3) is stopped (106) in a predetermined position by short-circuiting the branches (A, B, C) of the inverter (1) when the predetermined position
Type:
Application
Filed:
November 12, 2020
Publication date:
January 12, 2023
Applicant:
Valeo Systèmes d'Essuyage
Inventors:
Xiang Liu, Jose-Luis Herrada, Alexandre Paschutine, Mehdi Belhaj
Abstract: The present invention provides a method for producing active hepatocyte growth factor activator (HGFA) and active hepatocyte growth factor (HGF) without using animal serum. The present invention relates to a method for producing active HGFA without using animal serum. The method is characterized in that it comprises a step of obtaining a culture supernatant comprising pro-HGFA by culturing mammalian cells expressing inactive hepatocyte growth factor activator (pro-HGFA) in a medium without serum, and a step of adjusting the culture supernatant comprising pro-HGFA obtained in the above step to weakly acidic to convert pro-HGFA into active HGFA. The present invention also relates to a method for producing active HGF with HGFA produced by said method.
Abstract: The present invention provides food products, nutritional programs, and methods for meeting nutritional needs of subjects with dementia and related cognitive disorders. In one embodiment, the invention provides a food product comprising a reversibly sealed container and a soup, wherein the soup is in the container and comprises a total volume of 200-2000 mls, a vegetable or meat component, 300 to 2500 calories, a macronutrient caloric distribution comprising: 20-80% fat, 10-45% protein, and 10-65% carbohydrate, about 2% to about 40% medium chain triglycerides, omega 3 fatty acids in an amount of 100 to 2000 mg and less than 20 solid food particles having a volume greater than about 20 cm3.
Abstract: An object of the present invention is to provide a lyophilized formulation having improved storage stability of hepatic growth factor compared to conventional lyophilized formulations. The present invention provides a lyophilized formulation comprising (1) a hepatic growth factor, (2) trehalose and (3) one or more compounds selected from the group consisting of arginine, histidine, lysine, meglumine, glutamic acid, aspartic acid, proline, creatine, creatinine, tris(hydroxymethyl)aminomethane, and pharmaceutically acceptable salts thereof.
Abstract: The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).
Type:
Grant
Filed:
July 6, 2018
Date of Patent:
January 10, 2023
Assignees:
President and Fellows of Harvard College, Eisai R&D Management Co., LTD.
Inventors:
Yoshito Kishi, Yanran Ai, Ning Ye, Qiaoyi Wang, Kenzo Yahata, Kentaro Iso, Santhosh Reddy Naini, Shuji Yamashita, Jihoon Lee, Isao Ohashi, Takashi Fukuyama
Abstract: A vehicle seat that accommodates at least two users includes a seating portion frame, a first backrest and a second backrest which are pivotally hinged to the seating portion frame according to a transverse axis, via a common hinge. The common hinge includes: a pivot pin comprising a first lateral portion, and a first housing arranged on the first backrest and receiving interiorly the first lateral portion by authorizing the rotation of the first backrest. The first lateral portion has a protruding rib and the first housing has a substantially keyhole shape, complementary with the radial section of the first lateral portion. The rib is oriented, according to an angle of between 30° and 60° relative to the vertical direction of the vehicle seat.
Abstract: The invention provides novel 8-azabicyclo[3.2.1]octane compounds of formula (I): wherein R1, R2, R3, A, and G are defined in the specification, or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
Type:
Grant
Filed:
July 7, 2020
Date of Patent:
January 10, 2023
Assignee:
THERAVANCE BIOPHARMA R&D IP, LLC
Inventors:
Daniel D. Long, John R. Jacobsen, Lan Jiang
Abstract: A processor system and computer-implemented method are provided for assigning view numbers to display elements of an autostereoscopic display for use in interleaving image data of different viewpoints of a scene on the basis of said assigned view numbers. The assignment is performed in an efficient yet accurate manner and may be easily adapted to different optical designs of such autostereoscopic displays, for example, in terms of pitch and/or slant of the optical elements used in such autostereoscopic displays, or to different sub-pixel layouts of the display panel.
Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a multi-RTK inhibitor, and the use of the combination therapies for the treatment of cancer. The multi-RTK inhibitor may be represented by Formula (I): wherein R1 is C1-6 alkyl or C3-8 cycloalkyl, R2 is a hydrogen atom or C1-6 alkoxy, and R3 is a hydrogen atom or a halogen atom. A tumor therapeutic agent is disclosed that combines a compound or pharmaceutically acceptable salt thereof represented by Formula I and an anti-PD-1 antibody.
Abstract: Example embodiments relate to methods and apparatuses for aligning a probe for scanning probe microscopy (SPM) to the tip of a pointed sample. One embodiments includes a method for aligning an SPM probe to an apex area of a free-standing tip of a pointed sample. The method includes providing an SPM apparatus that includes the SPM probe; a sample holder; a drive mechanism; and detection, control, and representation tools for acquiring and representing an image of a surface scanned by the SPM probe. The method also includes mounting the sample on the sample holder. Further, the method includes positioning the probe tip of the SPM, determining a 2-dimensional area that includes the pointed sample, performing an SPM acquisition scan, evaluating and acquired image, and placing the SPM probe in a position where it is aligned with an apex area of the free-standing tip of the pointed sample.
Type:
Grant
Filed:
September 23, 2019
Date of Patent:
January 10, 2023
Assignees:
IMEC VZW, Katholieke Universiteit Leuven, KU Leuven R&D
Inventors:
Kristof Paredis, Jonathan Op de Beeck, Claudia Fleischmann, Wilfried Vandervorst
Abstract: The system concerns a gear motor for a motor vehicle wiping system comprising:—an electric motor comprising a rotor, a stator and a rotating shaft solidly attached to the rotor,—a reducing mechanism connecting the rotating shaft and an output shaft of the gear motor.
Abstract: The present disclosure relates to an upholstery system for a vehicle seat, comprising: a foam lining comprising a front face and a rear face, a flexible covering which covers the front face of the foam lining, a rigid part which covers the rear face of the foam lining, at least one series of attachment systems, which are received as inserts in the foam lining, the attachment systems of the series being interconnected by at least one ball joint, and wherein the attachment systems are configured to ensure the attachment of the covering and of the rigid part onto the foam lining.
Abstract: A device for adjusting horological functions of a timepiece, including a mechanism for selection and actuation, including: a drive driving a driving pinion in the clockwise and anti-clockwise directions, a driven pinion driven when the driving pinion turns clockwise and anti-clockwise, the driven pinion moving into a first position by the driving pinion turning clockwise, in which the driven pinion actuates an actuator of a first horological function, and moving into a second position by the driving pinion turning anti-clockwise, in which second position, the driven pinion actuates an actuator of a second horological function, the driven pinion not actuating the actuator of the first horological function when it is in its second position, and vice versa. The mechanism for selection and actuation includes at least two driven pinions, and the adjusting device includes a control mechanism selectively bringing the driving pinion into engagement with each of the driven pinions.
Type:
Grant
Filed:
March 8, 2018
Date of Patent:
January 10, 2023
Assignee:
Manufacture d'Horlogerie Audemars Piguet SA
Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
Type:
Grant
Filed:
July 8, 2020
Date of Patent:
January 10, 2023
Assignee:
THERAVANCE BIOPHARMA R&D IP, LLC
Inventors:
Adam D. Hughes, Erik Fenster, Melissa Fleury, Roland Gendron, Edmund J. Moran
Abstract: A pressure relief valve and an electrolytic capacitor, including: a valve seat, wherein an exhaust passage is formed, an installation groove arranged on the top which communicates with the passage; a blocking cover, movably arranged on the groove between an open and a closed position for opening and closing the passage, a sealing ring arranged between the bottom of the cover and the groove, wherein at least part of the bottom wall forms a guide surface, which extends from the center of the cover radially outward and upward obliquely to the radial edge. The valve can be suitable for the installation of the capacitor to reduce the internal gas pressure therein, maintain the internal gas pressure within a safe range, and at the same time reduce the bulging of the bottom of the capacitor, so that the core package and the bottom are closely attached to achieve effective heat dissipation.
Type:
Grant
Filed:
June 11, 2021
Date of Patent:
January 10, 2023
Assignee:
DONGGUAN HEC TECH R&D CO., LTD.
Inventors:
Gang Li, Weifu Dong, Yingfeng Yu, Fengrong He, Mingxing Fu