Abstract: A method for functionalizing a surface of a dielectric plate that is transparent to visible light—to be able to examine the dielectric plate using optical microscopy—includes depositing a negative film on the dielectric slide. The negative film comprises a polymerizable composition that polymerizes when exposed to an electron beam. The polymerizable composition is polymerized—by exposing the negative film to the electronic beam—at a set of points representing a preset pattern. Non-polymerized portions of the polymerizable composition are dissolved—to develop the negative film—forming a set of pads of polymerized portions of the polymerizable composition. Each pad corresponds to one point of the preset pattern. A metal film is disposed on the negative film, and the developed negative film is dissolved to define holes through the metal film. Each of the holes corresponds to a base of one pad of the set of pads.

Abstract: In one aspect the application relates to a computing system for providing data for modelling a human brain comprises a database including a plurality of datasets (or allow access to a plurality of datasets), each dataset including at least a dynamical model of the brain including at least one node and a neurodataset of a neuroimaging modality input. The at least one node include a representation of a local dynamic model and a parameter set of the local dynamic model.

Abstract: The invention relates to a profiled structure elongated in a direction in which the structure has a length exposed to an airflow and transversely to which the structure has a leading edge and/or a trailing edge, at least one of which is profiled and has, along said direction of elongation, geometric serration patterns defined by a succession of peaks and troughs. Along the profiled leading edge and/or trailing edge, the serration patterns have a geometric pattern that is repeated in the direction of elongation, the shape of which is stretched and/or contracted transversely to the direction of elongation and/or in the direction of elongation.

Abstract: A device is dynamically isolated via a broadband switch that includes a plurality of cascade elements in series, wherein each cascade element comprises a first set of SQUIDs in series, a matching capacitor, and a second set of SQUIDs in series. The broadband switch is set to a passing state via flux bias lines during programming and readout of the device and set to a suppression state during device's calculation to reduce operation errors at the device. A device is electrically isolated from high-frequencies via an unbiased broadband switch. A device is coupled to a tunable thermal bath that includes a broadband switch.

Abstract: A system and method provide for installation and setup of a set-top box (STB) in a Digital TV network includes a mobile device running a mobile application, an operator application, and a display configured to display video from the STB. A status of the STB is determined and encoded into an optically scannable graphic displayed by the display. The optically scannable graphic is scanned with an optical device in communication with the mobile device and the status of the STB is decoded. The status of the STB is transmitted to the operator application compared with an acceptance criteria.

Abstract: Method for manufacturing microcapsules enclosing a substance referred to as the active substance, in which method: there are provided an aqueous solution of a surfactant, an oily phase comprising the active substance and at least a first monomer X, and a polar phase having at least a second monomer Y; an O/W emulsion is prepared by adding the oily phase to the aqueous solution of the surfactant; the polar phase is added to the O/W emulsion in order to obtain a polymer by polymerisation of the X and Y monomers; starting from this reaction mixture, the microcapsules are isolated and comprise a wall which is formed by the polymer and which encloses the active substance; the polymer is a poly(beta-amino ester).

Abstract: The present invention relates to a selective process for preparing sulfones from sulfides by enzymatic catalysis, and to a composition comprising a symmetrical sulfide, an oxidoreductase enzyme catalyzing the oxidation of said symmetrical sulfide to symmetrical sulfone; optionally at least one cofactor C of said enzyme E; and an oxidant, which allows in particular the implementation of said process.

Abstract: The present invention provides novel compounds (e.g., compounds of Formulae (I), (II), (III), (IV)) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or pharmaceutically acceptable salts thereof, optionally in a pharmaceutically acceptable carrier, and a medical uses thereof.

Abstract: The invention is directed to a foam precursor liquid and foam cleansing composition that comprise a cellulose ether and surfactant. The precursor liquid results in a foam with excellent lather characteristics upon dispensing from a pump foam dispenser, and the liquid does not thicken to impede or clog the dispenser it is dispensed from. The foam precursor liquid is easily pourable prior to dispensing and makes refilling and reusing pump foam dispensers very convenient for consumers conscious about using less plastic.

Abstract: The invention relates to a dispensing and spraying member intended for a cleaning system for a sensor unit of at least two optical sensors, the dispensing and spraying member being configured to dispense and/or spray at least one cleaning fluid onto at least one first optical surface of the sensor block and said member comprising an arm, which extends along a longitudinal axis, at least one supply cannula and one discharge cannula for the cleaning fluid, the arm comprising at least one plurality of openings for spraying the cleaning fluid onto at least the first optical surface.

Abstract: A flexible magnetic wrench holder is disclosed having a flexible elongated strip having a top wall, a bottom wall, a first side wall and a second side wall. The top wall has a plurality of stations each adapted to receive a wrench. The bottom wall includes a magnet retainer assembly in each station having a first magnet and a second magnet. The top wall of the flexible elongated strip is adapted to magnetically hold a wrench at each station with the first magnet and the bottom wall of the flexible elongated strip is adapted to magnetically attach to different shaped ferrous surfaces with the second magnet. Alternatively, the top wall may include a plurality of flexible tabs for holding the wrenches by mechanical hold and friction fit. The holder may be flexed and twisted.

Abstract: The present invention provides methods of treating malaria comprising administration of compounds of Formula (I) or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the variables are as defined herein. The invention also provides uses of the compounds of Formula (I), as defined herein, for the possible inhibition of plasmepsin X, plasmepsin IX or plasmepsin X and IX activity, for treating a Plasmodium infection, and for treating malaria. Also provided are methods of treatment further comprising administration of one or more additional anti-malarial compounds.

Abstract: Provided herein are compositions comprising aptamers that specifically bind monocytes and/or macrophage and methods for their use. These aptamer compositions can be used in methods for isolating and/or enriching monocytes and/or macrophages or depleting cell populations of monocytes and/or macrophages. Further provided are methods of using the aptamers or cell populations generated using them in the methods disclosed herein for therapies and/or drug delivery.

Abstract: A bottle configured to house and dispense items. The bottle comprises a body, a finish positioned above the body, and a ramp protruding into an interior space defined by the body. The body includes a base and a sidewall extending up from the base. The body defines the interior space for housing the items. The finish presents an opening for dispensing the items from the body. The ramp is formed with a concave shape configured to support one or more of the items.

Abstract: A vehicle seat for accommodating at least two users includes: a seating portion frame, a first backrest and a second backrest which are pivotally hinged to the seating portion frame according to a transverse axis via a common hinge. The common hinges includes: a pivot pin comprising at least one central portion having an outer wall, and a housing, having an inner wall, arranged on the seating portion frame, and receiving interiorly the central portion of the pivot pin, by immobilizing the pivot pin. The inner peripheral wall of the housing bears against the outer wall of the central portion. The outer wall of the central portion includes at least one elastically deformable rib so as to be maintained constantly bearing against the inner wall of the housing.

Abstract: The vehicle seat comprising a seat-bottom frame; a seatback frame comprising at least one first lateral riser mounted pivoting relative to said seat-bottom frame around a transverse axis; a first discontinuous type hinge mechanism with a first side-plate rigidly fixed to the seat-bottom frame and a second side-plate; an intermediate riser mounted on the seat bottom frame, pivoting around the transverse axis, by means of the first hinge mechanism where the intermediate riser and the second side-plate are securely connected in rotation around the transverse axis; where the intermediate riser is fixed to the first lateral riser at a distance from the transverse axis; where the intermediate riser has a stiffness less than the stiffness of the first lateral riser of the seatback frame.

Abstract: Example embodiments relate to methods and devices for generating (quasi-) periodic interference patterns. One embodiment includes a method for generating an interference pattern using multi-beam interference of electromagnetic radiation. The method includes computing a set of grid points in a complex plane representing a grid with a desired symmetry. The method also includes selecting a radius of a virtual circle. Additionally, the method includes selecting a set of grid points in the complex plane that lies on the virtual circle centered around a virtual center point. Further, the method includes associating an argument of each grid point of the selected set of grid points in the complex plane with a propagation direction of plane waves or quasi plane waves or parallel wave fronts. In addition, the method includes obtaining the interference pattern that is a superposition of the plane waves or quasi plane waves or parallel wave fronts.