Abstract: The present invention relates to a mechanical reduction gearing (1) comprising: —an input shaft (3), —a sun gear (5) coupled in rotation to the input shaft (3), —a planet carrier (7) rotatable with respect to the input shaft (3) and supporting an output shaft (74) coaxial with the input shaft (3), said planet carrier (7) comprising at least one planet shaft (s1, s2, s3) extending parallel to the input shaft (3), —at least one cam (13) arranged around the planet shaft (s1, s2, s3) and comprising a first axial portion (p1) concentric to the planet shaft (s1, s2, s3) and at least one second eccentric axial portion (p2, p3), said at least one planet shaft (s1, s2, s3) being mounted rotatably with respect to the planet carrier (7) and/or said at least one cam (13) being mounted rotatably with respect to the associated planet shaft, —at least one planet gear (15) coupled in rotation to the cam (13) at its first concentric axial portion (p1) and configured to engage with the sun gear (5), —a peripheral annulus (17)

Abstract: A damper for an object is placed in a medium subjected to vibrations. The damper has an idle state in the absence of vibrations, a first operating state in case of vibrations of a first type, and a second operating state in case of vibrations of a second type. The level of each vibration of the first type is less than the level of each vibration of the second type. The damper includes an outer support structure, an inner support structure, and at least one pair of membranes formed of a first membrane and a second membrane. Each membrane is formed of a viscoelastic material including fibers aligned substantially in a same direction.

Abstract: Methods for decreasing harmful effects of blue light on skin are disclosed that include topically administering to a subject in need thereof a composition of an effective quantity of a purified, enzymatic hydrolysate of Theobroma cacao L. beans comprising peptides and saccharides having a molecular weight between 200 Da and 10 kDa in a physiologically acceptable medium. The hydrolysate of Theobroma cacao L. beans is present in the composition at a concentration from 0.001 to 20% with respect to the total weight of the composition. The composition can be a cosmetic composition.

Abstract: The invention relates to a nickel-based superalloy comprising, in percentages by mass, 4.0 to 5.5% rhenium, 1.0 to 3.0 ruthenium, 2.0 to 14.0% cobalt, 0.3 to 1.0% molybdenum, 3.0 to 5.0% chromium, 2.5 to 4.0% tungsten, 4.5 to 6.5% aluminum, 0.50 to 1.50% titanium, 8.0 to 9.0% tantalum, 0.15 to 0.30% hafnium, 0.05 to 0.15% silicon, the balance being nickel and unavoidable impurities. The invention also relates to a single-crystal blade (20A, 20B) comprising such an alloy and a turbomachine (10) comprising such a blade (20A, 20B).

Abstract: The invention concerns a detergent composition containing less than 1 wt. % of phosphate, comprising: (a) from 2 to 25 wt. % of an alcohol ethoxylate of formula R1—(OCH2CH2)mOH where R1 is selected from saturated or monounsaturated linear C16 and/or C18 alkyl chains and where m is from 6 to 40; and, (b) from 2 to 25 wt. % of an alcohol ether sulfate of formula R2—(OCH2CH2)nOSO3H where R2 is saturated or monounsaturated linear C16 and/or C18 alkyl chain and n is from 5 to 20; wherein the mole ratio of (a) to (b) is from 9:1 to 1:9; the invention also concerns a domestic method of treating a textile.

Abstract: Topical personal care compositions for improving cellular energy efficiency by protecting skin from mitochondrial fragmentation that takes place in the cells of an aging individual in need thereof. Use of a topical personal care composition comprising niacinamide and of one or more cooperative skin benefit agents for reducing cellular mitochondrial fragmentation, which cooperative agents are selected from the group consisting of 1-methylnicotinamide chloride, N-acetylmethionine, mixtures thereof, and derivatives thereof. Use of niacinamide and cooperative skin benefit agent selected from 1-methylnicotinamide chloride, N-acetylmethionine, mixtures thereof, and derivatives thereof in the manufacture of a topical personal care composition for decreasing or preventing mitochondrial fragmentation in skin cells and for increasing skin cellular energy.

Abstract: The present disclosure provides improved genome editing compositions and methods for editing a human Wiskott-Aldrich syndrome gene. The disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of WAS, including but not limited to, an immune system disorder, thrombocytopenia, eczema, X-linked thrombocytopenia (XLT), or X-linked neutropenia (XLN).

Abstract: A frozen confection comprising freezing point depressant in an amount of 1 to 30 wt %, pulse protein in an amount of 0.4 to 10 wt % and lysine, wherein the weight ratio of plant protein to lysine is from 3:1 to 8:1.

Abstract: The disclosure may relate to a method for the characterization of the 3D orientation of an emitting dipole within a specimen. The method comprises splitting a light beam emitted by the emitting dipole and exiting an objective lens into a first and a second beams; spatially filtering said first beam by using a spatial frequency filter; splitting each of said filtered first beam and said second beam into two beams linearly polarized using polarizing beam splitters; detecting with an optical detection unit four beams linearly polarized in a detection plane optically conjugated with the front focal plane of said microscope objective lens; determining, from four intensity images, in a predefined frame of the specimen, the mean orientation and the angular aperture of the distribution of the 3D orientation of the emitting dipole, during an acquisition time of said four intensity images.

Abstract: The device for discharging liquids for a module includes sensor/transmitter blocks for a vehicle. The module includes a first block having a lower optical surface having an upper limit, and at least one second block having at least one upper optical surface with a lower limit arranged above the lower optical surface. The device extends from an area defined by at least one portion of the lower limit of the at least one second block and the upper limit of the first block, and is configured to discharge liquids flowing from the at least one upper optical surface to an area other than the lower optical surface.

Abstract: The invention concerns a surfactant composition comprising: (a) from 10 to 90 wt. % of an alcohol ethoxylate of formula R1-(OCH2CH2)mOH where R1 is oleyl and/or elaidic and where m is from 6 to 16; and, (b) from 10 to 90 wt. % of an alcohol ether sulfate of formula R2—(OCH2CH2)nOSO3H where R2 is saturated or monounsaturated linear C16 and C18 alkyl chain and n is from 5 to 20; wherein the total level of (a)+(b) is greater than 80 wt. %; a detergent composition comprising said surfactant composition; and a domestic method of treating a textile, the method comprising the step of: treating a textile with an aqueous solution of 0.5 to 20 g/L of said detergent composition.

Abstract: Topical cosmetic compositions containing a 4-substituted resorcinol derivative along with N-acetyl methionine exhibit improved storage stability and oxidative stability. A method of stabilizing 4-ethyl resorcinol or 4-hexyl resorcinol in a composition comprising a cosmetically acceptable vehicle by adding to the composition Acetyl Methionine in an amount sufficient to stabilize said 4-ethyl resorcinol or 4-hexyl resorcinol. Use of the N-Acetyl Methionine and stabilized 4-substituted resorcinol derivatives in the manufacture of a topical cosmetic composition.

Abstract: The invention relates to a wiper motor having a housing element connected to an electrical line that has an elastically deformable spring element in an end region projecting out of the housing element, wherein the spring element, in order to form an electrically conductive connection with a counterpart element on the housing element, is movable, with respect to a first, relaxed position of the spring element, into a second, elastically deformed position generating a contact force on the counterpart element.

Abstract: A valve system/method suitable for an internal combustion engine (ICE), compressor pump, vacuum pump, and/or reciprocating mechanical device is disclosed. The system/method is optimized for construction of a two-stroke ICE. The rudimentary system incorporates an intake engine block cover (IEC) and exhaust engine block cover (EEC) that enclose an intake rotary valve cylinder (IVC) and exhaust rotary valve cylinder (EVC) that control intake/exhaust flow through a respective intake rotary valve port (IVP) and an exhaust rotary valve port (EVP) into and out of a combustion cylinder that provides power to a piston and crankshaft. Intake/exhaust multi-staged valves (IMV/EMV) provide intake/exhaust flow control for the IVC/IVP and EVC/EVP. An enhanced system may include a variety of intake/exhaust port seals (IPS/EPS), forced induction/discharge (FIN/FID), centrifugal advance (CAD/ICA/ECA), and/or cooling channel spool (ICS/ECS).

Abstract: A rail for a vehicle seat having first and second sliding rail members driven by a motorized drive mechanism. The rail further comprises a mechanical lock actuated by a relative movement between the motorized drive mechanism and the second rail member in the event of an accident.

Abstract: Compositions disclosed herein, and methods of use thereof included those for treating or preventing sepsis in a subject in need, including methods of extending of the survival of a subject suffering from sepsis, and reduction of organ dysfunction or failure due to sepsis. Methods of treating or preventing sepsis in a subject in need includes administering compositions comprising early apoptotic cells or early apoptotic cell supernatants. Compositions and methods of use thereof may reduce the negative proinflammatory effect accompanying sepsis. Further, anti-inflammatory cytokine release may be reduced. In certain instances, compositions may include additional agents.

Abstract: The present invention relates to a gear motor (101), in particular for a wiper system, comprising: -a brushless DC electric motor (103) including: -a rotor; -a stator having coils for electromagnetically exciting the rotor; -a device for determining the angular position of the rotor; -a control unit configured to generate control signals for supplying power to the electromagnetic excitation coils of the stator; -a reduction mechanism (104) that is linked on one side to the rotor of the electric motor (103) and on the other side to an output shaft (109), the reduction mechanism (104) having a predefined reduction ratio and; -an output angular position sensor (110) that is configured to measure the angular position of the output shaft (109), wherein the output angular position sensor (110) that is configured to transmit a signal corresponding to the measured angular position of the output shaft (109) to the device for determining the angular position of the rotor and said device is configured to determine the p

Abstract: A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-y1)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.

Abstract: A resonant waveguide grating includes a waveguiding layer and a plurality of subwavelength structures. The waveguiding layer, being in optical proximity to the plurality of subwavelength structures, is configured to guide at most ten wave-guided light modes. The plurality of subwavelength structures includes at least two adjacent grooves having a subwavelength distance between their groove centers being different than the subwavelength distance between the centers of two adjacent ridges. The plurality of subwavelength structures is configured to couple out of the waveguiding layer resonantly by diffraction, an outcoupled fraction of an incoupled portion of incident light. The outcoupled fraction is a diffracted part of an incident light beam. A diffractive optical combiner and a diffractive optical coupler, both include the resonant waveguide grating of the invention. A near-eye display apparatus includes at least the resonant waveguide grating of the invention.

Abstract: Disclosed is a self-invertible inverse latex including, as an inverting agent, surfactant species of the polyglycerol ester family; the use thereof as a thickening and/or emulsifying and/or stabilising agent for a cosmetic, dermopharmaceutical or pharmaceutical topical composition, and cosmetic, dermopharmaceutical or pharmaceutical topical compositions containing same. Also disclosed is a new surfactant composition containing polyglycerol esters.