Abstract: A switched-capacitor converter has a first and second terminal; a switched-capacitor ladder network having a plurality of serially connected first capacitors defining a plurality of flying capacitor nodes; a plurality of serially connected second capacitors defining a plurality of output capacitor nodes, wherein nodes of the flying capacitor nodes can be connected to nodes of the output capacitor nodes in a plurality of ladder converter configurations to perform a switched-capacitor ladder power conversion; and a switch matrix to connect the first terminal to different flying capacitor nodes and/or to connect any flying capacitor node to any other flying capacitor node or output capacitor node according to different switch configurations. Also, a switched-capacitor converter assembly may have a plurality of serially and/or parallel connected switched-capacitor reconfigurable switched-capacitor ladder converters.

Abstract: A contractile tissue-based analysis device is provided, in which a strip of contractile tissue is supported by support structure. The support structure comprises a substantially planar base element, and first and second support pillars extending from said base element. An optical detection device is arranged on the side of the base element opposite to said support pillars, and is arranged to capture image data from at least one of the head portions of the support pillars. The motion of the support pillars induced by the strip of contractile tissue can thus be captured from below, i.e. through the planar base element.

Abstract: An on-chip interferometer and a spectrometer including the interferometer are provided. An on-chip interferometer includes a waveguide for propagation of an optical signal including an input waveguide; at least two interferometer arms having one or more slot waveguides; and an output waveguide; wherein the input waveguide is split into the at least two interferometer arms which are recombined into the output waveguide; and a control mechanism configured for controlling a relative time delay between optical signals propagating in the two interferometer arms by modifying one or more slot widths of one or more of the slot waveguides; and wherein the relative time delay is at least 1, 2, 5, or at least 10 fs or at least one optical period of the longest optical wavelength of the optical signal.

Abstract: A quantum random number generator includes an entropy source having a laser source, a single photodiode configured for generating photo current based on received light from the laser source, where the photodiode has a non-unity quantum efficiency for allowing interference of the light from the laser source with a vacuum state to obtain entropy from the vacuum state, a transimpedance amplifier to convert the photo current into voltage, an analog-to-digital converter for converting the analog voltage to a digital output, a security proof which establishes a lower bound on the entropy from the vacuum state, and a processing unit configured to convert the digital output from the analog-to-digital converter to random numbers based on the security proof.

Abstract: An apparatus includes a processing pipeline with a stationary structure motion corrector, a stationary structure remover and a flowing structure detector. The stationary structure motion corrector is configured to motion correct stationary structure in a series of ultrasound images for subject motion, wherein the series of ultrasound images includes the stationary structure and flowing structure. The stationary structure remover is configured to remove the stationary structure from the motion corrected series of ultrasound images thereby producing flow images of the flowing structure. The flowing structure detector is configured to detect peaks of flow of the flowing structure in the flow images over time to generate images of detected flow peaks. The images of detected flow peaks are accumulated over time to generate a high resolution ultrasound image.

Abstract: Disclosed is apparatus and method for motion tracking of a subject in medical brain imaging. The method comprises providing a light projector and a first camera; projecting a first pattern sequence (S1) onto a surface region of the subject with the light projector, wherein the subject is positioned in a scanner borehole of a medical scanner, the first pattern sequence comprising a first primary pattern (P1,1) and/or a first secondary pattern (P1,2); detecting the projected first pattern sequence (S1?) with the first camera; determining a second pattern sequence (S2) comprising a second primary pattern (P2,1) based on the detected first pattern sequence (S1?); projecting the second pattern sequence (S2) onto a surface region of the subject with the light projector; detecting the projected second pattern sequence (S2?) with the first camera; and determining motion tracking parameters based on the detected second pattern sequence (S2?).

Abstract: A magnetron plasma sputtering arrangement including an evacuable chamber, wherein in the evacuable chamber a tuning electrode, operatively connected to a biasing source with respect to ground, and including an aperture defining at least one axis of length, is arranged in a flow path for plasma between a sputtering head and a substrate. A plasma sputtered material originating at a sputtering target will traverse the aperture before depositing onto the surface of the substrate as a thin film.

Abstract: The present invention relates to the production of bacteriocins, and in particular the production of bacteriocins of class I or II by recombinant expression in coryneform bacteria as the bacterial cell host. Also provided are modified coryneform bacteria for use as production hosts for production of bacteriocins.

Abstract: Methods for evolving cells or strains towards improved methyltransferase activity, particularly SAM-dependent methyltransferase activity, as well as to cells and strains useful in such methods and methods of using the evolved cells in the production of methylated products.

Abstract: Disclosed is a gasification unit (1) for producing a product gas. The gasification unit (1) comprises a co-current or counterflow pyrolysis unit (2) including a pyrolysis gas outlet (3) arranged at an upper part (4) of the pyrolysis unit (2) and a pyrolysis gas inlet (5) arranged at a lower part (6) of the pyrolysis unit (2). The gasification unit (1) further comprises a co-current or counterflow gasifier (7) including a product gas outlet (8) arranged at an upper part (9) of the gasifier (7) and a gasifier inlet (10) arranged at a lower part of the gasifier (7) and coke moving means (12) for allowing pyrolyzed coke (13) to move from the pyrolysis unit (2) to the gasifier (7).

Abstract: Systems and methods for assessment of one or more suspected conditions of an individual that include receiving collaborative identification data pertaining to features of a suspected condition and subject-specific phenomena of presentation, selecting target phenomena, receiving quantitative hypotheses for the target phenomena, defining an observation protocol comprising instructions for how the individual is to self-monitor and register observations by interaction with a portable data acquisition system, upon each occurrence of the target phenomena, directing the individual to provide the stored data upon observation of a target phenomenon during observation periods, transmitting the stored data from the portable data acquisition system to the analysis component, directing the individual to recall each observation period, completing one or more quantitative comparisons between any of the stored data, the quantitative hypotheses, and the recollection, inferring the suspected conditions, and determining a conti

Abstract: The present invention relates to excipients for stabilizing active agents, in particular peptides, polypeptides, nucleic acids, viruses, virus-like particles, proton pump inhibitors and antibiotics. The excipient reduces aggregate and/or particle formation in preparations comprising said agents. The excipient is a diamide of a dicarboxylic acid comprising at least one N—H amido group, at least one unsubstituted or substituted N-hydroxyethylamido group and/or at least one unsubstituted N-hydroxymethylamido group. In particular, the excipient is N,N,N?,N?-tetrakis-(2-hydroxyethyl) adipinic acid amide.

Abstract: The present disclosure relates to an optical line terminal that can be used in an optical fiber access system based on passive optical networks. The present disclosure further relates to a PON system; in particular the optical line terminal can be configured such that colourless components can be employed in a PON system using the optical line terminal and such that wireless communication can be directly employed in a PON system.

Abstract: The present disclosure relates to an optical fiber access system based on passive optical networks. In particular the present disclosure relates to a PON system with increased capacity and a method for increasing the capacity in a PON system. One embodiment relates to an optical line terminal for a passive optical network, comprising at least one transmitter for generating a time division multiplexed (TDM) downstream optical data signal, a first time lens optical signal processor configured to convert the downstream TDM signal to a downstream WDM signal for distribution to a plurality of users, and at least one receiver for receiving and processing an upstream signal from said users.

Abstract: In certain embodiments a light therapy system (e.g., phototherapy device), such as for treatment of Alzheimer's disease, depression, dementia, short-term memory, or for improved learning, improved athletic performance or improved cognitive performance, is provided where the light system comprises a blue light source that operates at a frequency in the range from 20 to 50 Hz (preferably around 40 Hz), whereby the system enables retinal ganglion cells of a human to be exposed in order to stimulate brain waves (gamma oscillations in the human's brain).

Abstract: The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty alcohol acetates and derivatives thereof, from a yeast cell.

Abstract: The invention provides a novel class of natural azaphilone pigments, called atrorosins, and methods for their production. The methods for the production of atrorosins include production by fermentation using a fungal species belonging to the genus Talaromyces, preferably the species Talaromycesatroroseus. The use of the novel atrorosins pigments as a colouring agent for food items and/or non-food items, and for cosmetics.

Abstract: An ionic conductive, stretchable, and flexible transparent material includes silk fibroin, a nanomaterial, and an electrolyte. The material can be recycled. A flexible surface capacitive touch panel and a flexible motion sensor can both be based on the ionic conductive, stretchable, and flexible transparent material. The ionic conductive, stretchable, and flexible transparent material shows many desirable properties, such as a good crystallinity, transparency, mechanical strength, recyclability, optical transparency, and electrical sensitivity. The material shows chemical and thermal stability, in addition to excellent dimensional stability.

Abstract: An apparatus for carrying out polarization resolved Raman spectroscopy on a sample (15), in particular a crystalline sample, comprises: at least one light source (11), in particular at least one laser, for providing excitation radiation to a sample (15), a spectrograph (31) for dividing light from the sample (15), in particular Raman scattered light from the sample (15), into at least one spectrum of spatially separated wavelength components and for directing at least a portion of the at least one spectrum to a detector (29), in particular a CCD detector, a polarization state control element (27) for the light from the sample (15), the polarization state control element (27) being arranged in a light path of at least one light beam (25) traveling from the sample (15) towards the detector (29), and the polarization state control element (27) comprising at least one polarization sensitive optical element (45, 47), in particular a Wollaston prism, the at least one polarization sensitive optical element being

Abstract: Herein are provided microbial factories, in particular yeast factories, for production of strictosidine aglycone and optionally other plant-derived compounds. Also provided are methods for producing strictosidine aglycone in a microorganism, as well as useful nucleic acids, vectors and host cells.