Abstract: A self-powered module for gesture recognition is presented that utilizes small, low-cost photodiodes for both energy harvesting and gesture sensing. Operating in the photovoltaic mode, photodiodes harvest energy from ambient light. In the meantime, the instantaneously harvested power from individual photodiodes is monitored and exploited as a clue for sensing finger gestures in proximity. Harvested power from all photodiodes is aggregated to drive the whole gesture-recognition module including a micro-controller running the recognition algorithm. A robust, lightweight algorithm is provided to recognize finger gestures in the presence of ambient light fluctuations. Two prototypes are fabricated to facilitate user's interaction with smart glasses and smart watches.

Abstract: Disclosed herein are image apparatuses comprising a frontside surface, a backside surface, a storage region (e.g., a storage node or a floating diffusion node), the storage region being situated closer to the frontside surface than to the backside surface, a storage well situated between the backside surface and the storage region, and a doping region situated between the storage region and the storage well. An impurity type of the doping region is opposite an impurity type of the storage well. A lateral area of the storage well is greater than or equal to a lateral area of the storage region, and no portion of a lateral perimeter of the storage region extends outside of a lateral perimeter of the storage well.

Abstract: In an embodiment, the present disclosure pertains to a method of determining an angular motion in a subject. The method generally includes one or more of the following steps of: (1) applying a wearable system to a body region of the subject; (2) utilizing the wearable system to sense one or more parameters; and (3) correlating the one or more parameters to the angular motion in the subject. In an additional embodiment, the present disclosure pertains to a wearable system for determining angular motion in a subject. Generally, the wearable sensor includes one or more fabrics for sensing one or more parameters of a body region of a subject.

Abstract: In an embodiment, the present disclosure pertains to a method of sensing an analyte in a sample by: (1) exposing the sample to an electrode that includes a covalent-organic framework with a plurality of metal-coordinated aromatic units that are linked to one another by aromatic linkers; (2) detecting a change in a property of the electrode; and (3) correlating the change in the property to the presence or absence of the analyte. In an additional embodiment, the present disclosure pertains to said covalent-organic frameworks. Additional embodiments of the present disclosure pertain to methods of making the covalent-organic frameworks.

Abstract: Some embodiments provide a color image sensor and color image sampling method that uses multiple-layer pixels and is capable of producing color images without using absorption color filters (e.g., such as employed in conventional CFAs). In accordance with some embodiments of the color image sensor device and color image sampling method, frequency-dependent reflectors are incorporated between the photodetection layers of multiple-layer (e.g., two layer) pixels.

Abstract: In an embodiment, the present disclosure pertains to a method of making a composite. In some embodiments, the method includes applying an external magnetic field to a mixture composed of a plurality of magnetic materials in a container, in which the external magnetic field produces a homogenous and uniform magnetic flux in the container. In some embodiments, the method further includes solidifying the mixture to result in the growth of solvent crystals in the mixture, and subliming a solvent phase of the mixture in the container to thereby form a composite having uniformly aligned magnetic materials. In an additional embodiment, the present disclosure pertains to a composite having uniformly aligned magnetic materials. In some embodiments, a majority of the magnetic materials in the composite are aligned in the same direction.

Abstract: The present invention provides for the manipulation of cofactor usage in a recombinant host cell to increase the formation of desirable products. In some embodiments, the invention provides for a recombinant microorganism comprising a mutation in one or more native enzymes such that their cofactor specificity is altered in such a way that overall cofactor usage in the cell is balanced for a specified pathway and there is an increase in a specific product formation within the cell. In some embodiments, endogenous enzymes are replaced by enzymes with an alternate cofactor specificity from a different species.

Abstract: The present specification provides RXR agonist compounds, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such RXR agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection.

Abstract: The present specification provides RXR agonists with both remyelination promotion and immunomodulatory activities, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat a demyelination-related disorder by both promoting remyelination of neurons and modulating the immune system.

Abstract: Some embodiments provide an image sensor that includes (i) quanta image sensor having an array of jots and configured for spatial and temporal oversampling, and (ii) a polarization filter array monolithically integrated with the quanta image sensor, so as to provide for a polarization image sensor. The image sensor may also include a color filter array.

Abstract: The invention provides a supramolecular polymer composition capable of co-assembly to maintain a three dimensional (3-D) macrostructural form after 3-D printing, made of a solvent, a template molecule; and a reactive component. The reactive component can be at least one monomer that is capable of hydrogen bonding with the template molecule to form a 1D supramolecular structure. The template may be an amphiphilic polymer. The monomer has at least two pendant groups capable of covalent crosslinking. The invention also includes a 3-D structure formed by crosslinking a 3-D printed supramolecular polymer composition, which optionally has a mesoporous structure. Also included is a method of manufacturing a 3-D structure by delivering a supramolecular polymer composition onto a surface of a substrate to form the 3-D structure.

Abstract: Aspects of the disclosure provide a sensing apparatus including a sensing device, a memory, and processing circuitry. The sensing device includes resonators having respective resonant frequencies. The resonators include an array of inductive coils positioned on a surface of the apparatus. The sensing device can output a signal indicating changes of the resonant frequencies caused by presence of an object proximate to the surface. The memory stores reference signals corresponding to reference objects. Each reference signal indicates changes of the resonant frequencies caused by the respective reference object proximate to the surface. The processing circuitry can receive, from the sensing device, a particular signal indicating changes of the resonant frequencies caused by presence of a particular object proximate to the surface. The processing circuitry compares the particular signal with the stored reference signals of the reference objects to determine an identity of the particular object.

Abstract: A self-powered module for gesture recognition is presented that utilizes small, low-cost photodiodes for both energy harvesting and gesture sensing. Operating in the photovoltaic mode, photodiodes harvest energy from ambient light. In the meantime, the instantaneously harvested power from individual photodiodes is monitored and exploited as a clue for sensing finger gestures in proximity. Harvested power from all photodiodes is aggregated to drive the whole gesture-recognition module including a micro-controller running the recognition algorithm. A robust, lightweight algorithm is provided to recognize finger gestures in the presence of ambient light fluctuations. Two prototypes are fabricated to facilitate user's interaction with smart glasses and smart watches.

Abstract: An infrared (IR)-based gesture sensing and detection system that includes at least one IR sensor for sensing micro gestures of one or more heat-radiating bodies made within a gesture-sensing region located proximate to the IR sensor. Each unique micro gesture may be used as a control gesture for controlling one or more controllable devices. Non-limiting examples of controllable devices include smart wearable device, handheld computing devices, and smart appliances, among many others. In some embodiments, each IR sensor is a passive IR sensor based on a pyroelectric material, and the IR-based gesture sensing and detection system is configured to consume minimal power to operate.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner.

Abstract: Embodiments of the present disclosure pertain to compositions that include: (1) a microalgal co-product; and (2) microalgae whole cells. In some embodiments, the microalgal co-product is derived from Nannochloropsis sp., and the microalgae whole cells include Schizochytrium sp. In some embodiments, the compositions of the present disclosure are completely free of fish oil and fishmeal. Additional embodiments of the present disclosure pertain to methods of cultivating aquatic species by applying the compositions of the present disclosure to a water source that contains the aquatic species. The methods of the present disclosure may be utilized to cultivate numerous aquatic species (e.g., freshwater tilapia) and improve various metabolic parameters in the aquatic species.

Abstract: Embodiments include a device, comprising: a column line; a plurality of pixels; each pixel coupled to the column line; a comparator having an input coupled to the column line and configured to compare a signal from the column line to a threshold; and control logic coupled to the pixels and configured to selectively couple each pixel to the column line after a sampling period for each pixel.

Abstract: Systems and methods for monitoring a range of motion of a joint are described. For example, in one embodiment, a first set of sensors may sense accelerations of a first body portion located on a first side of the joint and a second set of sensors may sense accelerations of the second body portion located on a second opposing side of the joint. The acceleration data may then be used to compute the relative motion of the first and second body portions to determine movement of the joint. This joint movement may then be used to determine one or more range of motion movement metrics which are output for viewing by a subject or medical practitioner.

Abstract: The present invention is a method for enhancing the quality and survival of red blood cells during storage by depleting the red blood cells of both carbon dioxide and oxygen and maintaining 2,3-diphosphoglycerate acid levels.