Patents Assigned to Debiotech S.A.
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Publication number: 20120172820Abstract: A micro-needle (4) comprising a sharp tip (31), an elongated body (32) and a head (36) containing at least two parallel independent lumens (5,6), each of said lumens (5,6) communicating with a distal side opening (7,8) of the head (36); said openings (7,8) being essentially oriented in a direction which is perpendicular with respect to its lumen (5,6) main direction and wherein the distal top end (33,34) of said lumen (5,6) is in the head (36) of the micro-needle (4).Type: ApplicationFiled: May 19, 2010Publication date: July 5, 2012Applicant: DEBIOTECH S.A.Inventors: Francois Cannehan, Astrid Cachemaille
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Publication number: 20120143124Abstract: The invention relates to a method for prescribing a dialysis treatment comprising the following steps: collecting patient specific data, determining at least one target, defining a series of values of the type [V;t] which allow to achieve said target wherein V represents the volume of dialysate used and t the duration of treatment, based on said patient specific data, displaying said series of values on a map. The invention also relates to a system using this method.Type: ApplicationFiled: November 2, 2011Publication date: June 7, 2012Applicant: DEBIOTECH S.A.Inventors: Diego MASTALLI, Alfio Quarteroni, Paolo Zunino
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Publication number: 20120048403Abstract: The regulator comprises at least a cylinder (2) with a fluid inlet connector (1) for receiving fluid at an inlet pressure and a fluid outlet connector (4) for delivering fluid, at least one chamber (3), a rod (5) in said cylinder with one side submitted to the inlet pressure and the other side submitted to the outlet pressure generating a net force counter-balanced by at least one spring means (7) acting on one side of said rod (5) against said inlet pressure, wherein a fluidic pathway is formed between said rod (5) and said cylinder (2) as the major fluidic resistance of the device, wherein a change of the inlet pressure induces a move of the rod along the axis of the cylinder thereby modifying the fluidic resistance of said fluidic pathway, wherein the fluidic resistance of said pathway varies with the applied pressure at the inlet in a predefined range of pressure, inducing a regulated flow rate in the considered range of pressure.Type: ApplicationFiled: May 20, 2010Publication date: March 1, 2012Applicant: DEBIOTECH S.A.Inventors: Eric Chappel, Frédéric Neftel
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Publication number: 20120029937Abstract: A dialysis device comprising a prescriber interface and a programming means configured to allow, via the prescriber interface, input of a set of therapeutic objectives and a treatment plan and a re-evaluation means configured to, as a function of the therapeutic objectives and the treatment plan, suggest at least one treatment option comprising a set of settings of a treatment session to achieve said set of therapeutic objectives.Type: ApplicationFiled: March 24, 2010Publication date: February 2, 2012Applicant: DEBIOTECH S.A.Inventors: Frédéric Neftel, Pascal Bernard, Thomas Hertz
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Publication number: 20120029325Abstract: Device for determining the characteristics of peritoneal membrane comprising means for measuring glucose in the fluid drainage and a processing unit comprising means for determining the characteristics of the membrane as a function of that rate of glucose measured at different times. The invention also relates to a method for determining the characteristics of peritoneal membrane including the consideration of glucose measured at different moments in the liquid drainage.Type: ApplicationFiled: July 12, 2011Publication date: February 2, 2012Applicant: DEBIOTECH S.A.Inventor: Frédéric Neftel
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Patent number: 8104352Abstract: The present invention relates to a pressure measurement unit to determine positive and negative fluid pressure within a disposable for medical devices. As part of the disposable, the invention consists of a rigid measurement chamber, which is covered by an elastic form part. This measurement chamber can be connected to a medical device, which is equipped with a pressure transducer. Specific shapes of the elastic form part and specific instrument interfaces ensure the connection between this elastic form part, the measurement chamber and the pressure transducer to exclude the influence of atmospheric pressure during measurements. The coupling and the sealing ability against atmospheric pressure is controllable. Such pressure measurement units can be used to measure fluid pressure in disposable to control for example fluid pumps.Type: GrantFiled: January 20, 2007Date of Patent: January 31, 2012Assignee: Debiotech S.A.Inventors: Hans-Gerd Evering, Didier Vecten, Florent Junod
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Patent number: 7901727Abstract: The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: —providing a support having a surface, —depositing on said surface one mono-layer of temporary particles, —depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, —eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment, —applying a coating fixation step, characterized by the fact that said temporary particles are deposited on said surface in such a way that, after particle deposition, more than 50% of the temporary particles are in contact with a maximum of two adjacent particles and otherwise are separated by an empty space.Type: GrantFiled: September 15, 2006Date of Patent: March 8, 2011Assignee: Debiotech S.A.Inventors: Heinrich Hofmann, Frederic Neftel, Laurent-Dominique Piveteau
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Patent number: 7887509Abstract: Medical device for the delivery and/or the extraction of fluid to and/or from a patient, said medical device comprising a pumping unit (1) for pumping a fluid, a warming chamber (2) with an inlet (3) and an outlet (4) and containing a heating element (5) for warming said fluid, fluid volume measuring means (13-18) and a fluid line crossing said pumping and warming units (1, 2), characterized by the fact that said heating element (5) is adapted to be fully immersed in the fluid which is crossing said warming chamber (2) and by the fact that said fluid measuring means comprise temperature sensing means adapted to measure the fluid temperature on at least two separate points and electrical parameter measuring means for determining at least one electrical parameter such as current, power or frequency applied to said heating element (5). The invention also includes a method for using this device.Type: GrantFiled: December 29, 2006Date of Patent: February 15, 2011Assignee: Debiotech S.A.Inventors: Pierre Thiebaud, Didier Vecten, Yvan Favre, Hans-Gerd Evering
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Publication number: 20100256569Abstract: The present invention relates to a medical injection device for delivering medium to a patient comprising at least two microneedles, wherein microneedle tips are arranged with a distance.Type: ApplicationFiled: October 23, 2008Publication date: October 7, 2010Applicant: DEBIOTECH S.A.Inventors: Astrid Cachemaille, Francois Cannehan
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Patent number: 7782467Abstract: A method of measuring a volume in a fluid flow micromechanical device includes: a) providing and positioning an optical apparatus for measuring the profile of a surface; b) providing a device for acquiring and processing the images coming from the optical apparatus for measuring a profile; c) placing the moving member in a first position and then in a second position, and activating the optical apparatus for measuring the profile of the surface to direct a light beam on the reference face, and activating the image acquisition and processor device to obtain a first image in the first position of the moving member and a second image in the second position; and d) comparing the second image with the first image of the reference face to determine the variation in the volume of the cavity generated by the deformation of the moving member.Type: GrantFiled: January 24, 2006Date of Patent: August 24, 2010Assignee: Debiotech S.A.Inventor: Eric Chappel
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Publication number: 20090199917Abstract: The invention relates to a microfluidic device comprising a first plate forming the substrate and including at least one perforation and, on either side of said first plate, at several locations, a material for defining passage portions consisting, in at least one of said locations, of an activatable material varying in volume on activation, said material being disposed at said locations in an arrangement that, during a first phase and upon activation of at least one location consisting of said activatable material, transforms it from a first configuration to a second configuration, modifying a three-dimensional network corresponding, in the second configuration and depending on the selected location(s) that are activated in said first phase, to different liquid paths including passage portions in offset planes parallel to the plane of the first plate, at least on either side of said first plate, and between which at least one of said perforations is located.Type: ApplicationFiled: May 29, 2007Publication date: August 13, 2009Applicant: DEBIOTECH S.A.Inventors: Veronique Vallet, Frederic Neftel, Laurent-Dominique Piveteau, Niklaus Schneeberger
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Publication number: 20090187139Abstract: Peritoneal dialysis system comprising pumping means, therapy data receiving means and processing means, said processing means being designed to process said therapy data and to impart a switching sequence to said pumping means characterized by the fact that said processing means are furthermore designed to impart a specific exchange profile for each exchange cycle.Type: ApplicationFiled: February 7, 2007Publication date: July 23, 2009Applicant: DEBIOTECH S.A.Inventors: Diego Mastalli, Alfio Quarteroni, Paolo Zunino
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Publication number: 20090097037Abstract: The invention relates to a method of measuring a volume in a fluid flow micromechanical device (100) by optically measuring the profile of a surface therein, the method comprising the following steps: a) providing and positioning an optical apparatus (10; 50; 30; 70) for measuring the profile of a surface; b) providing means (24; 44; 64; 84) for acquiring and processing the images coming from the optical apparatus for measuring a profile; c) placing said moving member (133) in a first position and then in a second position, and activating said optical apparatus for measuring the profile of the surface to direct a light beam on said reference face, and activating the image acquisition and processor means to obtain a first image in said first position of the moving member (133) and a second image in said second position; and d) comparing said second image with said first image of said reference face to determine the variation in the volume of the cavity (138) generated by the deformation of the moving memberType: ApplicationFiled: January 24, 2006Publication date: April 16, 2009Applicant: DEBIOTECH S.A.Inventor: Eric Chappel
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Patent number: 7497840Abstract: The invention concerns a system and a method of use of said system for performing fluid administration on a patient, the system comprising: a liquid pump (1), a liquid distribution system (2) connected to said pump (1) in such a way that liquid can flow from the liquid distribution system (2) to the pump (1) and vice versa, liquid supply means (3) for supplying liquid to a patient (4) via said liquid distribution system (2) and said pump (1), a patient conduit (5) adapted for connecting said liquid distribution system (2) to a patient (4), the system being characterized by the fact that said liquid pump (1) is unidirectional and that said liquid distribution system (2) comprises switching means designed to alternatively connect the pump enter line (56) with the supply means (3) or with the patient conduit (5).Type: GrantFiled: August 2, 2004Date of Patent: March 3, 2009Assignee: Debiotech S.A.Inventors: Frederic Neftel, Florent Junod, Didier Vecten
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Patent number: 7311503Abstract: The fluid-flow device (100) of the invention comprises a stack (30) covered by a closure wafer (20), said stack (30) comprising a support wafer (36), a layer of insulating material (34), and a silicon layer (32). The closure wafer (20) and/or said silicon layer (32) are machined so as to define a cavity (38) between said closure wafer (20) and said silicon layer (32), said support wafer (36) has at least one duct (102) passing right through it, said layer of insulating material (34) presenting at least one zone (35) that is entirely free of material placed at least in line with said duct (102) so as to co-operate with said cavity (38) to define a moving member (40) in said silicon layer (32), the moving member being suitable under the pressure of liquid in said cavity (38) for reversibly moving towards said support wafer (36) until contact is made between said moving member (40) and said support wafer (36).Type: GrantFiled: September 26, 2005Date of Patent: December 25, 2007Assignee: Debiotech S.A.Inventors: Harald T. Van Lintel, Didier Maillefer, Stephan Gamper
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Publication number: 20040167495Abstract: The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system (4) is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.Type: ApplicationFiled: February 12, 2004Publication date: August 26, 2004Applicant: DEBIOTECH S.A.Inventor: Frederic Neftel
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Patent number: 6716193Abstract: The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system (4) is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.Type: GrantFiled: June 17, 1999Date of Patent: April 6, 2004Assignee: Debiotech S.A.Inventor: Frédéric Neftel
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Patent number: 6558343Abstract: The present invention relates to the treatment of kidney insufficiency and more particularly to a peritoneal dialysis device. The device is adapted to function in tidal peritoneal dialysis (TPD) mode, the device being characterized by the fact that it is provided with a variation system for varying the parameters of dialysate exchange over time. The system is designed in such a manner as to vary the duration between two cycles for exchanging fractions of dialysate.Type: GrantFiled: September 29, 2000Date of Patent: May 6, 2003Assignee: Debiotech S.A.Inventor: Frédéric Neftel
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Patent number: 6364279Abstract: The invention relates to a closure device for closing a hose by pinching, and in particular for closing a flexible tube or hose used in the medical field. Essentially, the device comprises a closure piece (62) provided with a circularly arcuate slot (70) which is extended by a circular orifice (76). The closure piece (62) can be rotated about a point O on a circle of radius (R) equal to the radius of the slot (70).Type: GrantFiled: October 5, 2000Date of Patent: April 2, 2002Assignee: Debiotech S.A.Inventors: Frédéric Neftel, Bernard Bouvier
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Patent number: 6280430Abstract: An assembly comprising a flanged flask and a syringe device fixable thereto is provided. The syringe device includes a guide member for cooperating with the body of the flask. The guide member includes a first end with an internal guide surface at its terminal portion and a fastening mechanism set back from the internal guide surface. The internal guide surface cooperates with the cylindrical body of the flask and the fastening mechanism attached to the flange of the flask. A second end of the guide member provides translational guidance to a syringe.Type: GrantFiled: May 1, 1997Date of Patent: August 28, 2001Assignee: Debiotech S.A.Inventors: Frédéric Neftel, Bernard Bouvier