Abstract: Routing method for computing routes over uncertain geo-spatial data whereby only upon visiting the geographic entities it can be determined whether the needed service or product is actually provided and is adequate. When dealing with uncertain data, the returned route may need to go via several entities of the same type. Another routing method consists of finding an efficient and effective route from a starting point to an ending point going trough a predetermined number of objects, wherein each object represents a geographical entity of a unique type, and each object is selected from a distinct set of similar objects.
Type:
Grant
Filed:
July 9, 2008
Date of Patent:
February 26, 2013
Assignees:
University of Toronto, Technion Research & Development Foundation Ltd., Yissum Research Devolpment Company of the Hebrew University of Jerusalem Ltd.
Abstract: A method of changing the volume of an intra-bilayer membrane space of at least one bilayer membranous structure of a target tissue. The method comprises providing at least one characteristic of a target tissue having at least one bilayer membranous structure, selecting an acoustic energy transmission pattern set to change a volume of an intra-bilayer membrane space of a bilayer membrane of the at least one bilayer membranous structure according to the at least one characteristic, and applying acoustic energy on the target tissue according to the selected acoustic energy transmission pattern.
Type:
Application
Filed:
May 5, 2011
Publication date:
February 21, 2013
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Eitan Kimmel, Shy Shoham, Boris Krasovitski
Abstract: A device, a computer readable medium and a method that may include performing a shortened read attempt of multiple data memory cells that store data to provide an estimate of the data; wherein the shortened read attempt has a duration that is shorter than a duration of a full read attempt; performing a shortened read attempt of redundant memory cells that store redundant information to provide an estimate of the redundant information; wherein the estimate of the redundant information is indicative of an expected number of data memory cells that store a certain logic value; determining, based on the estimate of the data, an estimated number of data memory cells that store the certain logic value; comparing the expected number to the estimated number; and providing the estimate of the data as a read result if the expected number and the estimated number equal each other.
Type:
Application
Filed:
July 12, 2012
Publication date:
February 21, 2013
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A method includes accepting an analog input signal including a sequence of pulses of a given pulse shape. The analog input signal is distributed to multiple processing channels (40) operating in parallel. The analog input signal is sampled by performing, in each of the multiple processing channels, the operations of: mixing the analog input signal with a different, respective modulating waveform to produce a mixed signal; filtering the mixed signal; and digitizing the filtered mixed signal to produce a respective digital channel output.
Type:
Application
Filed:
April 5, 2011
Publication date:
February 14, 2013
Applicant:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
Inventors:
Yonina Eldar, Kfir Gedalyahu, Ronen Tur
Abstract: A method of generating pancreatic progenitor cells is disclosed. The method comprises: (a) differentiating stem cells under conditions such that at least a portion of the cells express glucose transporter 2 (GLUT2) so as to generate GLUT2-expressing cells; and (b) enriching for the GLUT2-expressing cells so as to generate a population of GLUT2 enriched cells, wherein at least 80% of the population of GLUT2 enriched cells express GLUT2, thereby generating pancreatic progenitor cells. Isolated populations of cells generated according to the method, pharmaceutical compositions comprising same and uses thereof are also disclosed.
Type:
Application
Filed:
April 12, 2011
Publication date:
February 7, 2013
Applicant:
Technion Research & Development Foundation Ltd.
Inventors:
Joseph Itskovitz-Eldor, Bettina Fishman, Hanna Segev
Abstract: The present invention provides a system for measuring biomarker analytes indicative of various diseases comprising an array of sensors sensitive to volatile organic compounds. Particularly, the system is composed of a random network of single-walled carbon nanotubes (SWCNTs) coated with non-polar small organic molecules in conjunction with learning and pattern recognition algorithms. Methods of discriminating between breath samples of healthy individuals and of lung cancer patients are disclosed.
Type:
Grant
Filed:
May 27, 2009
Date of Patent:
February 5, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: An output buffer and a source driver for a display panel are provided. The output buffer includes a differential input stage, a bias current source, a feedback module, and an output stage. The differential input stage has a first input terminal and a second input terminal receiving a first input signal and a second input signal respectively, and a first output terminal. The bias module provides a bias current to the differential input stage. The output stage has a second output terminal coupled to the first input terminal for providing an output current to the second output terminal based on a signal of the first output terminal. The feedback module adjusts the bias current and the output current based on the first input signal and the second input signal. The output buffer has ability of switching the output voltage to be low level and high level in high-speed.
Type:
Grant
Filed:
September 30, 2008
Date of Patent:
February 5, 2013
Assignees:
Himax Technologies Limited, NCKU Research & Development Foundation
Inventors:
Chien-Hung Tsai, Jia-Hui Wang, Ching-Chung Lee
Abstract: A light emitting system is disclosed. The system comprises an active region having a stack of bilayer quantum well structures separated from each other by barrier layers. Each bilayer quantum well structure is formed of a first layer made of a first semiconductor alloy for electron confinement and a second layer made of a second semiconductor alloy for hole confinement, wherein a thickness and composition of each layer is such that a characteristic hole confinement energy of the bilayer quantum well structure is at least 200 meV.
Type:
Grant
Filed:
February 21, 2011
Date of Patent:
February 5, 2013
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: Provided is a device comprising at least two layers, said at least two layers being at least partially overlapping (e.g., superposed) and contacting one another, wherein a first layer of said at least two layers comprises a non-biodegradable mesh, and wherein a second layer of the at least two layers comprises an electrospun element, and wherein the device is devoid of an extracellular matrix generated by mesenchymal progenitor cells, which are characterized by a reduced differentiation potential into an adipogenic lineage by at least about 50% as compared to differentiation potential of mesenchymal stem cells from an adult adipose source under identical assay conditions, and by an increased osteogenic differentiation potential by at least about 20% as compared to the osteogenic differentiation potential of adipose-derived MSCs under identical assays conditions.
Type:
Application
Filed:
July 26, 2012
Publication date:
January 31, 2013
Applicants:
Health Corporation - Rambam, Technion Research & Development Foundation Ltd.
Abstract: A method for protecting a communication network against failure, comprising the steps of: a) obtaining a primary network, represented by a graph of nodes and links, wherein each link has an associated capacity; b) computing a backup network, that includes nodes of the primary network and links that are not in the primary network; c) when a link of the primary network fails, rerouting communication traffic, through one or more links of the backup network, in order to bypass the failed link. Methods are suggested to determine the backup network, one method relates to expressing the objective and constraints on the backup network as linear or integer expressions, and a linear or integer programming tool is used to solve the equation system and provide optimal backup network.
Type:
Application
Filed:
July 31, 2012
Publication date:
January 31, 2013
Applicant:
TECHNION- RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: Anti CMV antibodies are provided. Thus an antibody of the present invention comprises an antigen recognition domain capable of binding an MHC molecule being complexed with a cytomegalovirus (CMV) pp65 or pp64 peptide, wherein the antibody does not bind said MHC molecule in an absence of said complexed peptide, and wherein the antibody does not bind said peptide in an absence of said MHC molecule. Also provided are methods of using the antibodies.
Type:
Grant
Filed:
March 27, 2008
Date of Patent:
January 29, 2013
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A method for forming a plurality of semiconductor light emitting devices includes forming an epitaxial layer having a first type doped layer, a light emitting layer, and a second type doped layer on a first temporary substrate. A second temporary substrate is coupled to an upper surface of the epitaxial layer with a first adhesive layer. The first temporary substrate is removed from the epitaxial layer to expose a bottom surface of the epitaxial layer. A permanent semiconductor substrate is coupled to the bottom surface of the epitaxial layer with a second adhesive layer. The second temporary substrate and the first adhesive layer are removed from the upper surface of the epitaxial layer. A plurality of semiconductor light emitting devices are formed from the epitaxial layer on the permanent semiconductor substrate.
Type:
Application
Filed:
July 19, 2011
Publication date:
January 24, 2013
Applicants:
PHOSTEK, INC., NCKU RESEARCH AND DEVELOPMENT FOUNDATION
Abstract: A method for forming a plurality of semiconductor light emitting devices includes forming an epitaxial layer having a first type doped layer, a light emitting layer, and a second type doped layer on a first temporary substrate. The epitaxial layer is separated into a plurality of epitaxial structures on the first temporary substrate. A second temporary substrate is coupled to the epitaxial layer with a first adhesive layer and the first temporary substrate is removed from the epitaxial layer. A permanent semiconductor substrate is coupled to the epitaxial layer with a second adhesive layer. The second temporary substrate and the first adhesive layer are removed from the epitaxial layer. The permanent semiconductor substrate is separated into a plurality of portions with each portion corresponding to at least one of the plurality of epitaxial structures to form a plurality of semiconductor light emitting devices.
Type:
Application
Filed:
July 19, 2011
Publication date:
January 24, 2013
Applicants:
PHOSTEK, INC., NCKU RESEARCH AND DEVELOPMENT FOUNDATION
Abstract: A semiconductor light emitting device and a method for making the semiconductor light emitting device are described. The semiconductor light emitting device includes an epitaxial structure having a first type doped layer, a light emitting layer, and a second type doped layer. The epitaxial structure may further include an undoped layer. A substrate is bonded to at least one surface of the epitaxial structure with an adhesive layer. One or more posts are located in the adhesive layer. The posts may have different widths depending on the location of the posts and/or the posts may only be located under certain portions of the epitaxial structure.
Type:
Application
Filed:
July 19, 2011
Publication date:
January 24, 2013
Applicants:
PHOSTEK, INC., NCKU RESEARCH AND DEVELOPMENT FOUNDATION
Abstract: The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.
Type:
Application
Filed:
September 14, 2012
Publication date:
January 24, 2013
Applicant:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
Abstract: Disclosed are recombinant polypeptides that include (a) a filaggrin amino acid sequence and (b) a cell importation signal sequence that includes a motif of two to fifteen amino acids, wherein the motif includes at least one arginine residue and at least one methionine residue. Also disclosed are nucleic acids encoding the recombinant polypeptides of the present invention, and compositions that include the recombinant polypeptides and nucleic acids of the present invention. Methods of treating or preventing a skin disease or skin disorder using the compositions of the present invention are also included, as well as kits that include a sealed containing that includes a recombinant polypeptide of the present invention.
Abstract: Antibodies are provided. For as example, an antibody capable of binding an artificial receptor which comprises a hydroquinone monolayer and is incapable of binding the artificial receptor when comprising a benzoquinone monolayer. Also provided are methods and systems using same for control delivery of a molecule-of-interest into a tissue.
Type:
Grant
Filed:
September 20, 2007
Date of Patent:
January 15, 2013
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Uri Sivan, Yoram Reiter, Arbel Artzy-Schnirman
Abstract: A method and pharmaceutical compositions useful for inhibiting the growth of solid tumors are provided. Specifically, the method is effected by administering to a subject in need thereof an agent capable of upregulating the expression level and/or activity of at least a functional portion of Sef, wherein the functional portion being capable of inhibiting RTK-mediated cell proliferation. Also provided are methods and kits for diagnosing and staging of cancer by detecting the expression level of hSef in a tissue sample, wherein a decrease in hSef expression level is indicative of cancer.
Type:
Grant
Filed:
December 7, 2009
Date of Patent:
January 15, 2013
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: An isolated primate embryonic cell is provided as well as cell cultures and cell lines derived therefrom. Also provided are methods of generating and using such cells.
Type:
Grant
Filed:
October 11, 2005
Date of Patent:
January 15, 2013
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A sorbent polymer is provided that interacts or reacts with aqueous urea to aid the regeneration of a dialysate liquid. The sorbent polymer may include one or more specific functional groups bonded thereto. Such specific functional groups are selected from carboxylic acids, carboxylic acid esters, carboxylates, amides, dicarboxylic acids, dicarboxylic acid esters, and dicer boxylates to produce the desired urea sorbent.
Type:
Application
Filed:
July 3, 2012
Publication date:
January 10, 2013
Applicants:
The Technion Research and Development Foundation, Ltd., Fresenius Medical Care Holdings, Inc.