Abstract: A method for managing communication among a plurality of social network members. The method comprises defining a multi participant task, setting at least one forward rule limiting the distribution an invitation message for participating in the multi participant task, forwarding the invitation message to at least one addressee from a plurality of social network members, allowing the at least one addressee to forward the invitation message to at least one additional addressee from the plurality of social network members under the at least one forward rule, monitoring a plurality of feedbacks to the invitation message to determine whether the multi participant task is achieved, and updating a status of the multi participant task according to the determination.
Type:
Application
Filed:
May 19, 2011
Publication date:
November 24, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: The present invention concerns methods of reducing the antigenicity of a proteinaceous compound while maintaining the compounds biological activity, as well as proteinaceous compositions with biological activity but reduced antigenicity. These methods and compositions have significant benefits to a subject in need of such compounds and compositions. Also included are modified toxin compounds that are truncated and/or possess reduce antigenicity. Such designer toxins have therapeutic, diagnostic, and preventative benefits, particularly as immunotoxins. Methods of treating cancer using these immunotoxins are provided.
Abstract: The present invention relates to nucleic acids and antibodies against Olfml-3 and Olfml-3 protein function in angiogenesis. Angiogenesis-related conditions, such as cancer or wound healing, can be treated by the composition comprising the Olfml-3 antagonists or agonists, respectively.
Type:
Application
Filed:
November 30, 2009
Publication date:
November 24, 2011
Applicant:
RESEARCH DEVELOPMENT FOUNDATION
Inventors:
Beat A. Imhof, Marijana Miljkovic-Licina, Philippe Hammel
Abstract: A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di(1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.
Type:
Application
Filed:
January 10, 2010
Publication date:
November 17, 2011
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A method of embedding the edit distance metric into the Hamming distance metric with low distortion. In other words, two input character strings are mapped to two corresponding output bit strings such that the Hamming distance between the output strings is approximately proportional to the edit distance between the two corresponding input strings.
Type:
Grant
Filed:
February 28, 2006
Date of Patent:
November 15, 2011
Assignees:
The Regents of the University of California, The TRDF Research & Development Foundation Ltd
Abstract: Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload and oxidative stress, eg. a neurodegenerative or cerebrovascular disease or disorder, a neoplastic disease, hemochromatosis, thalassemia, a cardiovascular disease, diabetes, a inflammatory disorder, anthracycline cardiotoxicity, a viral infection, a protozoal infection, a yeast infection, retarding ageing, and prevention and/or treatment of skin ageing and skin protection against sunlight and/or UV light. The iron chelator function is provided by a 8-hydroxyquinoline, a hydroxypyridinone or a hydroxamate moiety, the neuroprotective function is imparted to the compound e.g. by a neuroprotective peptide, and a combined antiapoptotic and neuroprotective function by a propargyl group.
Type:
Grant
Filed:
November 7, 2003
Date of Patent:
November 15, 2011
Assignees:
Technion Research and Development Foundation Ltd., Yeda Research and Development Co., Ltd.
Abstract: Geometric-waveform oscillator for processing light, the geometric waveform oscillator including a plurality of masses, at least one force producing element, and a plurality of elastic elements, each of the force producing elements being coupled with a respective one of the masses, at least one of the masses including a light processing module, each of the force producing elements applying a force to the masses, the elastic elements coupling the masses together, the elastic elements coupling the masses with a respective support, wherein the mass values of the masses, the force values of the forces, and the stiffness coefficients of the elastic elements, are selected such that the light processing module oscillates according to the geometric-waveform.
Type:
Grant
Filed:
April 20, 2004
Date of Patent:
November 8, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: The subject matter discloses a method of determining whether a point in a computerized image is visible from a viewpoint; said image is represented as a point cloud, the method comprising: performing inversion on a the vicinity of the point thus creating a computerized inversed objects each point in the vicinity of the point is related to a parallel point in the computerized inversed object and obtaining a convex hull of the inversed object; the point is likely to be visible from the viewpoint in case it belongs to the point set composing the convex hull.
Type:
Application
Filed:
May 24, 2009
Publication date:
November 3, 2011
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD
Abstract: Sensor array for detecting biomarkers for cancer in breath samples. The sensor array is based on 2D films or 3D assemblies of conductive nanoparticles capped with an organic coating wherein the nanoparticles are characterized by a narrow size distribution. Methods of use of the sensor array for discriminating between patterns of volatile organic compounds from healthy individuals and patients with various types of cancer are disclosed.
Type:
Application
Filed:
January 10, 2010
Publication date:
November 3, 2011
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A memory cell includes a pair of sub-cells, each including an access transistor, a storage transistor, and an isolation transistor that are serially coupled in sequence with their source/drain connected. The isolation transistor is shared with a sub-cell of an adjacent memory cell and always turned off, wherein the storage transistor is always turned on. A wordline is coupled to a gate of the access transistor of each sub-cell, and complementary bit lines are respectively coupled to sources/drains of the access transistors of the pair of sub-cells, such that data bit may be accessed between the bit line and the corresponding storage transistor through the corresponding access transistor.
Type:
Application
Filed:
April 22, 2010
Publication date:
October 27, 2011
Applicants:
NCKU RESEARCH AND DEVELOPMENT FOUNDATION, HIMAX TECHNOLOGIES LIMITED
Abstract: A wave-guiding system and method for mode-selective transmission of a spatially coherent light beam is disclosed. The system comprises a wave-guide with an inlet and an outlet for transmitting one or more modes; a first mode-shaping optical element for shaping the spatially coherent light beam before it enters through the inlet of the wave-guide to a desired mode of the wave-guide; and a second mode-shaping optical element for shaping light beam after it exits from the outlet of the wave-guide for obtaining a desired vectorial field.
Type:
Grant
Filed:
August 28, 2007
Date of Patent:
October 25, 2011
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A human urocortin-related peptide with significant sequence homology to the CRF neuropeptide family was identified. A mouse cDNA was isolated from whole brain poly (A+) RNA that encodes a predicted 38 amino acid peptide protein designated herein as urocortin II. Both human URP and mouse Ucn II are structurally related to the other known mammalian family members, CRF and urocortin (Ucn). These peptides are involved in the regulation of the hypothalamic-pituitary-adrenal axis under basal and stress conditions, suggesting a similar role for URP and Ucn IL Synthesized Ucn-II and URP peptide binds with higher affinity to CRF-R2 than to CRF-R1 Ucn II and human URP appear to be involved in the regulation of body temperature and appetite and may play a role in other stress related phenomenon. These findings identify Ucn II and human URP as a new members of the CRF family of neuropeptides, which are expressed centrally and bind to CRF-R2.
Type:
Grant
Filed:
December 7, 2009
Date of Patent:
October 25, 2011
Assignee:
Research Development Foundation
Inventors:
Wylie W. Vale, Jr., Teresa M. Reyes, Paul E. Sawchenko, Jean E. Rivier, Kathy A. Lewis, John B. Hogenesch, Joan M. Vaughan, Marilyn H. Perrin
Abstract: The present invention relates to targeted killing of a cell utilizing a chimeric polypeptide comprising a cell-specific targeting moiety and a signal transduction pathway factor. In a preferred embodiment, the signal transduction pathway factor is an apoptosis-inducing factor, such as granzyme B, granzyme A, or Bax.
Abstract: A light emitting system is disclosed. The system comprises an active region having a stack of bilayer quantum well structures separated from each other by barrier layers. Each bilayer quantum well structure is formed of a first layer made of a first semiconductor alloy for electron confinement and a second layer made of a second semiconductor alloy for hole confinement, wherein a thickness and composition of each layer is such that a characteristic hole confinement energy of the bilayer quantum well structure is at least 200 meV.
Type:
Application
Filed:
February 21, 2011
Publication date:
October 20, 2011
Applicant:
Technion Research & Development Foundation Ltd.
Abstract: The present invention provides a system comprising an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
Type:
Application
Filed:
December 2, 2009
Publication date:
October 6, 2011
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A method is provided for producing semiconductor nanoparticles comprising: (i) dissolving a semiconductor compound or mixture of semiconductor compounds in a solution; (ii) generating spray droplets of the resulting solution of semiconductor compound(s); (iii) vaporizing the solvent of said spray droplets, consequently producing a stream of unsupported semiconductor nanoparticles; and (iv) collecting said unsupported semiconductor nanoparticles on a support.
Type:
Grant
Filed:
September 22, 2005
Date of Patent:
October 4, 2011
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A signal processing method includes sampling an analog signal, which has a spectral density defining one or more bands, to produce a digitized signal. A spectral transform of the digitized signal is expressed as a matrix multiplied by a vector, wherein the vector includes multiple elements that represent the spectral density of the analog signal as a function of frequency within respective spectral slices. Indices of a subset of the elements of the vector, in which the spectral density is concentrated, is determined. The analog signal is reconstructed from the digitized signal using the subset of the elements of the vector and a corresponding subset of columns of the matrix having the indices.
Type:
Grant
Filed:
January 23, 2008
Date of Patent:
October 4, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A hydrogel system comprising polymer-conjugated albumin molecules is provided for controlled release delivery of therapeutic agents. The polymer is a functionalized synthetic polymer, preferably PEG-diacrylate. The polymer-conjugated albumin is preferably mono-PEGylated albumin. The hydrogel system may comprise a matrix to which the polymer-conjugated albumin molecules are linked via a functional group of the polymer. The matrix may be formed from the same polymer of the polymer-albumin conjugate.
Type:
Application
Filed:
December 7, 2009
Publication date:
September 29, 2011
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function.
Type:
Grant
Filed:
June 2, 2005
Date of Patent:
September 27, 2011
Assignee:
Technion Research & Development Foundation Ltd.
Inventors:
Igor Sukhotnik, Naim Shehadeh, Raanan Shamir
Abstract: System and method for visually tracking a target object silhouette in a plurality of video frames under very general conditions. The tracker does not make any assumption about the object or the scene. The tracker works by approximating, in each frame, a PDF (probability distribution function) of the target's bitmap and then estimating the maximum a posteriori bitmap. The PDF is marginalized over all possible motions per pixel, thus avoiding the stage in which optical flow is determined. This is an advantage over other general-context trackers that do not use the motion cue at all or rely on the error-prone calculation of optical flow. Using a Gibbs distribution with a first order neighborhood system yields a bitmap PDF whose maximization may be transformed into that of a quadratic pseudo-Boolean function, the maximum of which is approximated via a reduction to a maximum-flow problem.
Type:
Grant
Filed:
March 23, 2007
Date of Patent:
September 27, 2011
Assignee:
Technion Research and Development Foundation Ltd.
Inventors:
Ido Leichter, Michael Lindenbaum, Ehud Rivlin