Abstract: The present invention relates to the serine threonine kinase 32C (STK32C) gene relevant to breast cancer and a use thereof, and particularly, to a composition for the diagnosis, prevention, or treatment of breast cancer using the STK32C gene. In the present invention, changes in breast cancer cells according to STK32C gene expression differences were identified, and a breast cancer inhibitory effect according to the inhibition of expression of the STK32C gene and YB-1, which is a substrate protein, were newly verified, and thus target therapies are expected in treatment of breast cancer through more fundamental approaches.

Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

Abstract: Provided is a method of treating ovotoxicity of an individual, including administering an Ulmi cortex extract to an individual in need of treatment. The present disclosure may exhibit an effect of preventing, alleviating, or treating ovarian aging or premature ovarian failure by inhibiting oxidative stress or ovotoxicity of the ovaries.

Abstract: A stroke diagnosis and prognosis prediction system includes: an image acquisition unit configured so as to receive a plurality of images including at least a part of a human brain; an image alignment unit for aligning the plurality of images on the basis of a standard brain image; a lesion area detection and mapping unit for respectively detecting lesion areas from the plurality of images, and mapping the detected lesion areas so as to generate one mapping image; a matching and correction unit, which scales a mapping image so as to match the same to the standard brain image and performs image correction on the mapping image; a three-dimensional image generation unit storing the mapping image in a three-dimensional data space, thereby generating a three-dimensional lesion image; and a stroke diagnosis unit for diagnosing a stroke on the basis of the three-dimensional lesion image.

Abstract: There is provided a sol-gel chip using a porous substrate for entrapping small molecules and a method for screening a small molecule-specific material using the same, and more particularly, a porous substrate sol-gel chip characterized in that a sol-gel composition for entrapping small molecules is spotted on a surface of the porous substrate, a method for manufacturing the porous substrate sol-gel chip for entrapping small molecules, and a method for screening a material specifically binding to the small molecules using the porous substrate sol-gel chip for entrapping small molecules. According to the present invention, the small molecules can be effectively entrapped in the chip and the inflow of aptamers can be maintained as compared with the existing methods and thus aptamers specific to an extensive range of small molecules can be more easily selected.

Abstract: The present invention provides an apparatus for molding gas hydrate pellets that includes: a pulverizer in which dehydrated gas hydrates are pulverized; a cooler having a rotating shaft provided therein, comprising a plurality of agitation blades installed along a height direction of the rotating shaft and configured to cool the gas hydrates to a predetermined temperature; a decompressor configured to decompress the cooled gas hydrates to a predetermined pressure; and a pellet molder configured to mold the decompressed gas hydrates to pellets.

Abstract: The present invention relates to a method for manufacturing a porous filter for fine spraying and a porous filter manufactured by the method. A nickel-palladium alloy material porous filter manufactured according to the present invention exhibits excellent corrosion resistance and metal ion elution mitigating effects and can adjust the size of drug particles, thereby allowing a drug to arrive at the desired site. In addition, a plating liquid having a particular composition in the present invention allows the manufacture of a porous filter with a desired thickness by effectively lowering the stress of palladium (Pd), and thus, in a fine sprayer for treating a respiratory disease, a microporous filter, which is capable of delivering a drug to the vicinity of alveoli while effectively preventing the elution of metal elements due to a drug, apparatus vibration, and the like, and a fine sprayer, which uses the microporous filter, can be manufactured.

Abstract: Disclosed is a method of adjusting a data transmission rate between a vehicle and an access point (AP) as an embodiment of the present invention. The method according to an embodiment of the present invention may include receiving a signal broadcast from at least one AP near a vehicle, transmitting and/or receiving data to and/or from a predetermined AP at a first data transmission rate R0 on the basis of the received signal, receiving and storing signals broadcast from a plurality of APs near the vehicle in every predetermined period while the vehicle is moving, determining the number NT of APs having broadcast signals with strength greater than or equal to a threshold value among the signals received from the plurality of APs, comparing the number NT of APs to the number NT-1 of APs having broadcast signals with strength greater than or equal to the threshold value in a previous period, and determining a data transmission rate between the vehicle and the AP on the basis of a result of the comparison.

Abstract: A method and apparatus for receiving feedback information of a transmitter in a mobile communication system are provided. The method includes determining a parameter related to a first user signal; transmitting the first user signal based on the parameter related to the first user signal to a receiver; and receiving feedback information associated with the first user signal and an interference signal based on the first user signal.

Abstract: Provided is a method for preventing or treating hepatitis C by administrating a composition including, as an active ingredient, a Vitidis Vinferae Radix extract or a fraction thereof and, more specifically, to a Vitidis Vinferae Radix extract which is extracted with water and alcohol or a mixed solvent thereof, or a fraction thereof, which have remarkably low hepatotoxicity and exhibit an excellent effect of selectively inhibiting genome replication of a hepatitis C virus, and thus can be useful for preventing or treating hepatitis C.

Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

Abstract: The present invention relates to a multiplex microfluidic device for selection of nucleic acid aptamers and a method for high-throughput selection of nucleic acid aptamers using the same, and more particularly to a multiplex microfluidic device (SELEX lap-on-a-chip) that uses an improved multiplex platform in place of the development of an aptamer for a single target and to a method for high throughput selection of aptamers using the same together with high-throughput sequencing. A multiplex microfluidic device according to the present invention can simultaneously detect aptamers for a plurality of targets, and it can greatly increase the screening throughput and greatly shorten the process time compared to conventional multiplex techniques.

Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

Abstract: Disclosed are a device and a method for manufacturing a natural gas hydrate. Provided is the device for manufacturing a natural gas hydrate comprising: an ice slurry generation unit for preparing ice slurry having 13-20% of ice at normal pressure; a first pipe, having one end connected to the ice slurry generation unit for withdrawing the ice slurry from the ice slurry generation unit, and in which a high-pressure pump for increasing pressure on the ice slurry is interposed; a hydrate preparation reactor, which is connected to the other end of the first pipe so as to receive the pressurized ice slurry, and to which natural gas is supplied and mixed, for generating natural gas hydrate slurry; a second pipe, having one end connected to the hydrate preparation reactor, for withdrawing the natural gas hydrate slurry; and a dehydrating portion, which is connected to the other end of the second pipe, for dehydrating the natural gas hydrate slurry.

Abstract: The present invention relates to a biological tissue biopsy device including a body extending in a longitudinal direction, an outer needle installed to be connected to one side of the body and be extended in a longitudinal direction and including a first tube having a hollow portion formed therein and a second tube disposed in a direction parallel to the first tube to guide a hemostatic substance, an inner needle provided inside the first tube and extending in a longitudinal direction, and a sliding means provided in the body and installed to be connected to one end of the inner needle so as to enable the inner needle to move forward and backward. Here, the sliding means causes the inner needle to move a predetermined distance from the hollow portion of the first tube and be inserted into a target site.

Abstract: The present invention provides methods of differentiating mesenchymal stem cells or adult stem cells into nerve cells by treating the mesenchymal stem cells or the adult stem cells with an electromagnetic field having a high intensity of 100 to 1,500 mT and a low frequency of 0.01 to 100 Hz. These methods also provide injecting the mesenchymal stem cells or adult stem cells into a subject prior to treating the mesenchymal stem cells or adult stem cells with an electromagnetic field having a high intensity of 100 to 1,500 mT and a low frequency of 0.01 to 100 Hz.

Abstract: Disclosed are 4-substituted-2-(5-substituted-1H-indol-2-yl)phenol derivatives for controlling the proliferation and migration of kinase-overexpressed cells. The phenol derivatives are represented by Formula 1: wherein X is selected from the group consisting of hydrogen, halogen, a cyano group, a trifluoromethyl (CF3) group, an amidine (C(?NH)NH2) group, and a 5-methyl-1,2,4-oxadiazole group, Y is selected from the group consisting of hydrogen, halogen, a phenyl group substituted with one or two substituents selected from the group consisting of halogen, methoxy, nitro, trifluoromethyl, and aminomethyl, CO—R?, COOR?, OH, O—R?, and NH—R?, each R? is independently selected from the group consisting of C1-C18 alkyl, alkenyl, alkynyl, and —Z-alkyl (wherein Z is a heteroatom selected from the group consisting of O, S, and N or is —(CH2)m—), and m is an integer from 0 to 5.

Abstract: The present invention relates to a method for screening a substance inhibiting protein-protein interactions, and more particularly to a method for screening a substance inhibiting protein-protein interactions, the method comprising using a protein chip having immobilized thereon spots comprising a mixture of a sol-gel material and a protein. According to the invention, a protein chip can be easily manufactured in a 96-well plate using a sol-gel material, whereby an inhibitor that inhibits protein-protein interactions can be easily screened from a library of natural substances.

Abstract: Provided is a method for eliminating an interference operating on a receiver of a transmitter in a communications system, which includes transmitting at least one user signal; changing user phase information to be separated from interference phase information by a preset difference, when receiving the user phase information of the user signal and the interference phase information of an interference signal from at least one receiver; and transmitting at least one other user signal according to the changed user phase information.

Abstract: A wind speed measurement apparatus includes a rotating shaft, at least one blades provided radially around the rotating shaft and rotated by force of wind exerted on the at least one blade, and a frame provided at one side of the at least one blade and having a space therein such that the rotating shaft penetrates through the space.