Abstract: Disclosed are a device and a method for manufacturing a natural gas hydrate. Provided is the device for manufacturing a natural gas hydrate comprising: an ice slurry generation unit for preparing ice slurry having 13-20% of ice at normal pressure; a first pipe, having one end connected to the ice slurry generation unit for withdrawing the ice slurry from the ice slurry generation unit, and in which a high-pressure pump for increasing pressure on the ice slurry is interposed; a hydrate preparation reactor, which is connected to the other end of the first pipe so as to receive the pressurized ice slurry, and to which natural gas is supplied and mixed, for generating natural gas hydrate slurry; a second pipe, having one end connected to the hydrate preparation reactor, for withdrawing the natural gas hydrate slurry; and a dehydrating portion, which is connected to the other end of the second pipe, for dehydrating the natural gas hydrate slurry.

Abstract: Provided are a ramp signal calibration apparatus and method and image sensor including the apparatus. The apparatus includes: an analog-to-digital converter (ADC) including a trimmable transistor having a gain value that varies according to stored data , and configured to receive a ramp signal in a state where the gain value is a first gain value, and to output first and second output signals; a subtractor configured to calculate a difference between the first and second output signals; a digital comparator configured to compare the difference with a reference value and to determine whether a slope of the ramp signal has changed; and a counter configured to change the stored data based on whether the slope of the ramp signal has changed, wherein when the counter changes the data, the first gain value of the trimmable transistor is changed to a second gain value according to the changed data.

Abstract: The present invention relates to a novel biphenyl derivative or a pharmaceutically acceptable salt thereof, a pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising the same as an active ingredient, and methods for treating inflammatory disease or autoimmune diseases with the pharmaceutical composition. Novel biphenyl derivatives according to the present invention promote the phagocytosis of macrophages and inhibit the chemotaxis to exhibit excellent inflammation terminating and anti-inflammatory effects and thus can be effectively used as therapeutic agents for inflammatory diseases or autoimmune diseases.

Abstract: A method of preparing one-dimensional trimanganese tetroxide (Mn3O4) nanoparticles from an exfoliated two-dimensional manganese dioxide (MnO2) nanosheet using a solid-state decomposition method, and Mn3O4 nanoparticles prepared according to the method are provided. The Mn3O4 nanoparticles can be prepared at a very low temperature without using an organic solvent or a chemical additive, compared to conventional synthesis methods.

Abstract: The present invention relates to a system for providing food expiration date information using a TTI (time temperature integrator) and a method for providing food expiration date information using the same. The system for providing the food expiration date information and the method for providing the food expiration date information using the same of the present invention includes: an input unit for receiving TTI information, food information, and distribution history information; a calculation unit for producing a TTI indication value corresponding to an expiration date of the food; and an output unit which determines and outputs a color corresponding to the expiration date of the food among stages of colors which can be expressed through the TTI according to time and temperature conditions using the TTI indication value.

Abstract: Disclosed are an apparatus and method of cell-based path planning for a mobile body and a computer-readable recording medium storing the method therein. The method includes receiving a configuration space including a start point and a goal point of the mobile body and position information of obstacles, determining a search order of the obstacles located in the configuration space, performing cell decomposition by repeatedly connecting a vertex of one of the obstacles to a vertex of another obstacle according to the determined search order, and performing cell decomposition by making an extended line from each of non-connected vertices in a direction of dividing vertical angle of each of the non-connected vertices into two.

Abstract: A fluid simulation method and apparatus is provided. The fluid simulation method according to an embodiment of the present invention comprises setting initial conditions of level set and velocity field for a simulation object and setting FLIP particles according to the set initial condition of the level set and the set initial condition of the velocity field; updating the level set and the velocity field by advection of the level set and the velocity field; reconstructing the updated level set and the updated velocity field; redeploying the FLIP particles for the simulation object; projecting the updated velocity field to have incompressibility; and updating velocity of each of the deployed particles.

Abstract: A fluid simulation method and apparatus is provided. The fluid simulation method according to an embodiment of the present invention comprises setting initial conditions of level set and velocity field for a simulation object and setting FLIP particles according to the set initial condition of the level set and the set initial condition of the velocity field; updating the level set and the velocity field by advection of the level set and the velocity field; reconstructing the updated level set and the updated velocity field; redeploying the FLIP particles for the simulation object; projecting the updated velocity field to have incompressibility; and updating velocity of each of the deployed particles.

Abstract: The present invention relates to a method and kit of detecting a target material using an aptamer, and more particularly to a method and kit for detecting a target material, in which a sample and a second aptamer are added to a first aptamer immobilized on a solid phase so as to form a bond sandwiched between the first aptamer, the target material and the second aptamer, to an FET sensor-based method and kit for detecting a target material, and to an AAO sensor-based method and kit for detecting a target material. The inventive method for a target material using an aptamer can detect even low-molecular-weight materials which were difficult to detect in the prior art, thereby enabling detection of disease-related metabolites, environmental pollutants and food toxins in solutions. In addition, the detection method of the present invention is a direct and simple method and is highly cost-effective, because it uses the aptamer which can be consistently reproduced and can be produced at low costs.

Abstract: A method of tracking a position of an eye is provided. The method of tracking a position of an eye includes converting an obtained image into a binary number image, classifying the corner of the eye, maximum and minimum values of a pupil of the eye, and extracting a feature point from the binary number image on which the binarization step is completed, calculating a distance and inclination between the corner and the pupil of the eye using the feature point extracted through the feature point extraction step, and determining a gaze direction of the eye based on the distance and inclination calculated through the distance and inclination calculation step.

Abstract: Provided is a method of preparing a red clay processed material using red clay and sodium hydroxide and a red clay processed material having anti-corrosive and virus disinfecting activity. Also, a method of preparing alkali ionized water having excellent anti-bacterial, virus disinfecting and anti-corrosive activity using the red clay processed material, alkali ionized water using the same, and a functional product including the same are provided. The red clay processed material and the method of preparing alkali ionized water using the same can reduce the reaction temperature and reaction time compared to a conventional process, thereby significantly reducing the production cost.

Abstract: Provided are a method of producing a polymer dispersed liquid crystal device with a cooling plate and a polymer dispersed liquid crystal device using the same. According to the producing method of the invention using the cooling plate capable of effectively removing heat with a simple method, it is possible to improve driving voltage characteristics and decrease a production cost of the polymer dispersed liquid crystal device.

Abstract: Disclosed is a silicon-carbon composite for a negative active material of a lithium secondary battery, including carbon nanofibers and silicon particles, wherein the silicon particles are coated with amorphous silica. In the silicon-carbon composite of the invention, silicon is provided in the form of a composite with carbon fibers and the surface of silicon particles is coated with amorphous silica, thereby reducing volume expansion upon lithium ion insertion and exhibiting superior ionic conductivity and electrical conductivity to thus maintain high capacity, and also, amorphous silica-coated silicon is positioned inside the carbon fibers having a one-dimensional structure, thus ensuring a large specific surface area and a stable composite structure.

Abstract: Disclosed is a method for selecting a source transmit antenna in a cooperative multiple-input and multiple-output (MIMO) communication system including a source node, a relay node and a destination node. The method includes determining a source transmit antenna selection metric such that a source-destination channel, a source-relay channel and a relay-destination channel are related to one another, and selecting a positive integer number of antennas such that the source transmit antenna selection metric is maximized.

Abstract: The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis. Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.

Abstract: Provided is an apparatus for analyzing an electroluminescence sample, which comprises: a pulse generator for applying a pulse driving signal to the electroluminescence sample; an electroluminescence (EL) detector for receiving electroluminescence which is emitted from the electroluminescence sample according to the application of the pulse driving signal, thereby acquiring a light-receiving signal; a temperature controller for varying the temperature of the electroluminescence sample; and an electroluminescence transient spectroscopy (ELTS) analysis unit for analyzing a change in a time division section of the light-receiving signal delayed depending on a change of the temperature of the electroluminescence sample, and acquiring information on a defect-type charge trap which exists in the electroluminescence sample.

Abstract: The present invention relates to specific markers capable of detecting the development of colorectal cancer and the colorectal cancer inhibitory effect of SeMet (selenomethionine) having a chemopreventive effect against colorectal cancer. When the expressions of the biomarkers according to the present invention are measured and the expression levels thereof are analyzed in combination, whether SeMet (selenomethionine) is to be administered to prevent colorectal cancer can be determined and the development of colorectal cancer and the inhibitory effect of SeMet (selenomethionine) against the development of colorectal cancer can be monitored. Thus, these markers can be effectively used to observe the colorectal cancer inhibitory effect of SeMet (selenomethionine) and the prognosis of colorectal cancer resulting from the intake of SeMet (selenomethionine).

Abstract: The present invention relates to a thermoelectric conversion device using a solvating material, the device comprising: a cell with a closed structure, comprising a metal ammonia or metal amine compound as a solvating material; a polarization or porous separation membrane; and a heating unit, which prevents the outflow of the solvating material and thus maintains the solvating material in a reversible state.

Abstract: Provided are a laser diode using zinc oxide nanorods and a manufacturing method thereof. The laser diode using zinc oxide nanorods according to one embodiment of the present disclosure includes: a wafer; an electrode layer formed on the wafer; a nanorod layer including a plurality of n-doped zinc oxide nanorods grown on the electrode layer; and a p-doped single crystal semiconductor layer that is physically in contact with the ends of the zinc oxide nanorods.