Abstract: A buck converter that is efficient in power consumption is disclosed. A buck converter in accordance with an embodiment of the present invention includes an error amplifier and a comparator, at least one of which is powered and operated while a PWM signal is a high signal.

Abstract: The present invention relates to kartogenin-conjugated chitosan particles with an improved sustained release property and biocompatibility. Effects of increases in biocompatibility, chondrogenic differentiation efficiency and retention time in the joints were confirmed by using kartogenin-chitosan microparticles or kartogenin-chitosan nanoparticles of the present invention, and thus targeted treatment, in the prevention or treatment of bone diseases, is enabled through a more fundamental approach.

Abstract: The present invention relates to a novel 4-(aryl)-N-(2-alkoxythieno[3,2-b]pyrazin-3-yl)-piperazin-1-carboxamide derivative compound useful in the prevention or treatment of cancer; a preparation method thereof; and a pharmaceutical composition comprising the same. The novel 4-(aryl)-N-(2-alkoxythieno[3,2-b]pyrazin-3-yl)-piperazin-1-carboxamide derivative compound of the present invention can effectively inhibit the growth of proliferating cells, and thus can be useful in the prevention or treatment of cancer.

Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.

Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

Abstract: The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, having same as an active ingredient. The inventors identified a novel compound containing BTL2 inhibitory activity, and experimentally confirmed that the present novel compound had an excellent effect on the enhancement of the cancer cell death, on the inhibition of the metastasis and chemotactic mobility, and on the anti-asthma activity. Therefore, the present novel compound can be used as a very effective pharmaceutical component for treating the inflammatory-related diseases.

Abstract: The present invention relates to a method for manufacturing a transistor according selective printing of a dopant. For the manufacture of a transistor, a semiconductor layer is formed on a substrate, and a dopant layer is formed on the semiconductor layer. In the formation of the dopant layer, an inkjet printing is used to selectively print an n type dopant or a p type dopant.

Abstract: The present invention relates to a Krueppel-like factor 10 (KLF10) gene expression inhibitor promoting cartilage differentiation, and more specifically, to: a composition for promoting chondrocyte differentiation or treating cartilage diseases, containing a KLF10 gene expression inhibitor promoting cartilage differentiation and inhibiting the hypertrophy and dedifferentiation of chondrocytes; a cell therapeutic agent containing the composition; a method for promoting cartilage differentiation in bone marrow stem cells, comprising a step of expressing the composition in bone marrow stem cells; and a method for screening a chondrocyte differentiation promoter or a chondrocyte therapeutic agent.

Abstract: Disclosed is a pullback system, which has a simplified and miniaturized structure and an advanced function. The pullback system includes a central unit, which includes a rotation transducer part that rotates, and a stretchable part that is connected to a side of the rotation transducer part to rotate together with the rotation transducer part and that has a stretchable property, and a first unit rotatably coupled to a portion of the central unit. As the first unit moves in a first direction oriented from the rotation transducer part to the stretchable part or in a second direction opposite to the first direction, the stretchable part contacts or stretches.

Abstract: The present invention relates to a lithium metal oxide having a nickel oxide layer formed on a surface thereof, and represented by Formula 1; and the lithium metal oxide can be prepared by a method of preparing a lithium metal oxide having a nickel oxide layer formed on a surface thereof, the method comprising steps of: (1) complexing a nickel precursor onto a surface of a lithium metal oxide; and (2) calcining, through a heat treatment, the lithium metal oxide—the surface of which is complexed with the nickel precursor—obtained in Step (1).

Abstract: Disclosed is a method of adjusting a data transmission rate between a vehicle and an access point (AP) as an embodiment of the present invention. The method according to an embodiment of the present invention may include receiving a signal broadcast from at least one AP near a vehicle, transmitting and/or receiving data to and/or from a predetermined AP at a first data transmission rate R0 on the basis of the received signal, receiving and storing signals broadcast from a plurality of APs near the vehicle in every predetermined period while the vehicle is moving, determining the number NT of APs having broadcast signals with strength greater than or equal to a threshold value among the signals received from the plurality of APs, comparing the number NT of APs to the number NT-1 of APs having broadcast signals with strength greater than or equal to the threshold value in a previous period, and determining a data transmission rate between the vehicle and the AP on the basis of a result of the comparison.

Abstract: Disclosed are a data concealment apparatus and a data concealment method using an Error Correction Code. According to exemplary embodiments of the present invention, it is possible to prevent important information from being easily exposed to a third person by generating encoding data through convolution encoding of input data and thereafter, concealing the encoding data on an image through adjustment of a pixel value on the image and minimize an error which can occur at the time of recovering the input data by extracting the encoding data from the image in a soft decision scheme and performing Viterbi-decoding on the extracted encoding data in order to recover the input data concealed in the image.

Abstract: A multi-grid method using a V cycle includes: obtaining a first intermediate solution and a first residual by smoothing a cell of a fine level; obtaining a cell of a coarse level by down-sampling the cell of the fine level and setting the first residual as a second residual of the cell of the coarse level; obtaining a high-frequency component solution of the cell of the fine level and obtaining a smoothed high-frequency component solution by smoothing the high-frequency component solution; obtaining a coarse solution in the cell of the coarse level; up-sampling and transferring the coarse solution to the cell of the fine level and obtaining a corrected intermediate solution by adding the first intermediate solution, the smoothed high-frequency component solution and the coarse solution; and obtaining a second intermediate solution by smoothing the corrected intermediate solution.

Abstract: The present relates to a filter needle coupled between a fixation member having a needle for injecting a medical fluid after filtering foreign substances contained in the medical fluid and a disposable syringe, the filter needle includes an outer housing having a front end portion to which the fixation member is coupled and a rear end portion to which the disposable syringe is coupled and a filtering unit which is disposed inside the outer housing, and in which a medical fluid supplied from the fixation member to the disposable syringe is passed through as is, while a medical fluid supplied from the disposable syringe to the fixation member is filtered.

Abstract: The present invention relates to novel compounds as HIF-1? inhibitors, manufacturing process thereof, and a pharmaceutical compositions. The compounds according to the present invention having inhibition activity against HIF-1?, can be used as a therapeutic prevention and/or treatment for various solid cancers such as colon cancer, liver cancer, stomach cancer and breast cancer. Also, the compounds according to the present invention are useful in the treatment of diabetic retinopathy and rheumatoid arthritis, which are aggravated by HIF-1?-mediated VEGFA expression.

Abstract: Disclosed is a wire knot delivery device, and more particularly, a wire knot delivery device for delivering and maintaining a knot of a medical wire in a medical procedure. The wire knot delivery device includes a first body, a second body parallel to the first body and moving relative to the first body, a first catching part connected to a side of the first body and caught by a side of the knot during the delivery of the knot, and a second catching part connected to a side of the second body and caught by another side of the knot during the delivery of the knot. As the second body moves, a distance between the first catching part and the second catching part is adjusted.

Abstract: The present invention provides a radio frequency identification (RFID)-integrated self-powered time-temperature integrator (TTI), which comprises an RFID and a self-powered TTI which is attached to the exterior of a package of food to output an electric signal indicating a storage state of the food and supplies the electric signal as an operating power of the RFID, in which the electric signal output from the self-powered TTI is a voltage corresponding to a rate of a change in quality of the food accompanied, the quality is calculated by an integration value of time-voltage, and an integration algorithm uses an integrated value, obtained by adding the voltage measured every hour, as a quality variable of the food.

Abstract: The present invention relates to a compound inhibiting HF-1 activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention demonstrates anticancer activity not by non-selective cytotoxicity but by inhibiting the activity of HIF-1, the transcription factor playing an important role in cancer cell growth and metastasis. Accordingly, the compound or the pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumors such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.

Abstract: The present invention relates to a method and system for reliable 3D shape extraction of a metal surface. In this method, images are acquired at the same time by simultaneously irradiating interference-free polarized lights to a metal object. A photometric stereo method is then applied based on the images except for images which make the extraction of a 3D shape of the metal object inaccurate.

Abstract: The present invention relates to a CT contrast agent for detecting a thrombus, comprising fibrin-targeted peptide sequence-conjugated glycol chitosan-gold nanoparticles. The CT contrast agent for detecting a thrombus according to an embodiment of the present invention may allow rapid and repeated acquisition of CT image information related to the size and location of a thrombus in cardio-cerebral vascular thrombosis, and also enables the imaging monitoring of cerebral thrombus.