Patents Assigned to Dongguk University
  • Publication number: 20170200898
    Abstract: The present invention relates to a carbon nanotube organic semiconductor, a manufacturing method thereof, and a thin film transistor for chemical sensor using the same. More specifically, the present invention provides a carbon nanotube organic semiconductor, a manufacturing method thereof, and a thin film transistor for chemical sensor using the same, where the carbon nanotube organic semiconductor is an organic semiconductor layer constituting an organic thin film transistor and comprising a conjugated polymer and a single-walled carbon nanotube, the single-walled carbon nanotube displaying semiconducting properties and being wrapped with the conjugated polymer.
    Type: Application
    Filed: June 26, 2015
    Publication date: July 13, 2017
    Applicant: DONGGUK UNIVERSITY INDUSTRAY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Yong Young NOH
  • Publication number: 20170200889
    Abstract: The present invention relates to a method for manufacturing a transistor according selective printing of a dopant. For the manufacture of a transistor, a semiconductor layer is formed on a substrate, and a dopant layer is formed on the semiconductor layer. In the formation of the dopant layer, an inkjet printing is used to selectively print an n type dopant or a p type dopant.
    Type: Application
    Filed: July 14, 2015
    Publication date: July 13, 2017
    Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Yong Young NOH
  • Publication number: 20170174645
    Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 22, 2017
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyeong LEE, Sei-Ryang OH, Kyung Seop AHN, Ok-Kyoung KWON, Doo-Young KIM, Hyung Won RYU, Jung Hee KIM, Xuezhen XU
  • Publication number: 20170152500
    Abstract: The present invention relates to a method of differentiating mesenchymal stem cells or adult stem cells into nerve cells by treating the mesenchymal stem cells or the adult stem cells with an electromagnetic field having a high intensity of 100 to 1,500 mT and a low frequency of 0.01 to 100 Hz. The present invention also relates to a medical device to which the method is applied. The method of differentiating nerve cells by using a magnetic field, and a composition according to the present invention induce the differentiation of adult stem cells into nerve cells by using a low-frequency, high-intensity electromagnetic field, so that nerve cells or neural stem cells can easily be differentiated through only electromagnetic field treatment in a short time.
    Type: Application
    Filed: April 2, 2015
    Publication date: June 1, 2017
    Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young Kwon SEO, Jung Keug PARK, Hee Hun YOON, Hyun Jin CHO, Hee Jung PARK, Yu Mi KIM, Bo-Young YOO, Sang Eun CHO, Sang Heon KIM
  • Publication number: 20170143714
    Abstract: Provided is a pharmaceutical composition for preventing or treating liver fibrosis, comprising a GPR119 ligand as an active ingredient. The composition comprising the GPR119 ligand as an active ingredient significantly inhibits the expression of collagen I, transforming growth factor ? (TGF?) and ?-smooth muscle actin (?-SMA), thereby inhibiting HSC activation, and also significantly inhibits HSC proliferation.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 25, 2017
    Applicants: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Keon Wook KANG, Kyeong LEE, Jin Won YANG
  • Publication number: 20170141319
    Abstract: The present invention relates to a carbon nanotube interlayer, a manufacturing method thereof, and a thin film transistor using the same. More specifically, the present invention provides a carbon nanotube interlayer, a manufacturing method thereof, and a thin film transistor using the same, where the carbon nanotube interlayer is a layer constituting an organic thin film transistor and comprising a conjugated polymer and a single-walled carbon nanotube between an organic semiconductor layer and a source/drain electrode. The conjugated polymer selectively wraps the single-walled carbon nanotube having semiconducting properties.
    Type: Application
    Filed: May 14, 2015
    Publication date: May 18, 2017
    Applicant: DONGGUK UNIVERSITY INDUSTRAY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Yong Young NOH
  • Publication number: 20170129879
    Abstract: Disclosed are 4-substituted-2-(5-substituted-1H-indol-2-yl)phenol derivatives for controlling the proliferation and migration of kinase-overexpressed cells. The phenol derivatives are represented by Formula 1: wherein X is selected from the group consisting of hydrogen, halogen, a cyano group, a trifluoromethyl (CF3) group, an amidine (C(?NH)NH2) group, and a 5-methyl-1,2,4-oxadiazole group, Y is selected from the group consisting of hydrogen, halogen, a phenyl group substituted with one or two substituents selected from the group consisting of halogen, methoxy, nitro, trifluoromethyl, and aminomethyl, CO—R?, COOR?, OH, O—R?, and NH—R?, each R? is independently selected from the group consisting of C1-C18 alkyl, alkenyl, alkynyl, and —Z-alkyl (wherein Z is a heteroatom selected from the group consisting of O, S, and N or is —(CH2)m—), and m is an integer from 0 to 5.
    Type: Application
    Filed: October 17, 2016
    Publication date: May 11, 2017
    Applicants: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, Dongguk University Industry-Academic Cooperation Foundation
    Inventors: Youngjoo BYUN, Chang Hoon LEE
  • Patent number: 9642870
    Abstract: The present invention relates to a composition for preventing, treating or alleviating atopic dermatitis comprising an immunosuppressant and a transglutaminase 2 inhibitor as active ingredients. Conjoint administration of an immunosuppressant and a transglutaminase 2 inhibitor according to the present invention makes it possible to achieve far better therapeutic effects than with administration of either an immunosuppressant or a transglutaminase 2 inhibitor alone, since there is a reduction in the dose of an immunosuppressant which is difficult to administer for a long time because of side effects and with which, when discontinued, lesions are liable to become exacerbated to the original state, and since an immunosuppressant is mixed with a transglutaminase 2 inhibitor which in some patients has a lackluster effect in treating atopic dermatitis.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: May 9, 2017
    Assignee: Dongguk University Industry-Academic Cooperation Foundation
    Inventor: Ai-Young Lee
  • Patent number: 9596663
    Abstract: A method and apparatus for transmitting a training sequence code of a transmitting apparatus with a plurality of transmitting antennas in a communication system are provided. A transmitting apparatus allocates a plurality of time slots for the plurality of transmitting antennas to be divided into at least one frame, and sends a training sequence code with reference power for any one of the transmitting antennas, and sends remaining training sequence codes for remainders of the transmitting antennas with transmission power from zero to the reference power, in any one of the time slots. A receiving apparatus receives a plurality of training sequence codes for a plurality of transmitting antennas through any one of the plurality of receiving antennas from a transmitting apparatus, and selects one of the training sequence codes having the greatest reception power to estimate a channel. This may improve a channel estimation performance in a communication system.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: March 14, 2017
    Assignees: Samsung Electronics Co., Ltd, Dongguk University Industry Academic Cooperation Foundation
    Inventors: Jong Soo Choi, Byoung Jo Choi, Seung Hoon Hwang, Young Bum Kim, Ho Yong Lim
  • Publication number: 20170049773
    Abstract: The present invention relates to a pharmaceutical composition containing a G protein coupled receptor 119 (GPR119) ligand as an active ingredient for preventing or treating non-alcoholic fatty liver disease. More particularly, it was confirmed that the GPR119 ligand, which has been developed as only an anti-diabetic drug, exhibits superior effects on the treatment of non-alcoholic fatty liver and the signal pathways in hepatocytes therefor differ from the signal pathways in the small intestine and the pancreas exhibiting anti-diabetic effects, whereby the GPR119 ligand can be useful to treat non-alcoholic fatty liver.
    Type: Application
    Filed: January 23, 2015
    Publication date: February 23, 2017
    Applicants: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, SNU R&DB FOUNDATION
    Inventors: Keon Wook KANG, Kyeong LEE, Jin Won YANG
  • Patent number: 9578268
    Abstract: Provided are a ramp signal calibration apparatus and method and image sensor including the apparatus. The apparatus includes: an analog-to-digital converter (ADC) including a trimmable transistor having a gain value that varies according to stored data, and configured to receive a ramp signal in a state where the gain value is a first gain value, and to output first and second output signals; a subtractor configured to calculate a difference between the first and second output signals; a digital comparator configured to compare the difference with a reference value and to determine whether a slope of the ramp signal has changed; and a counter configured to change the stored data based on whether the slope of the ramp signal has changed, wherein when the counter changes the data, the first gain value of the trimmable transistor is changed to a second gain value according to the changed data.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: February 21, 2017
    Assignees: SAMSUNG ELECTRONICS CO., LTD., Dongguk University Industry-Academic Cooperation Foundation
    Inventors: Dae-Yun Kim, Min-Kyu Song, Yeon-Seong Hwang, Jae-Jung Park
  • Publication number: 20170016003
    Abstract: The present invention relates to a Krueppel-like factor 10 (KLF10) gene expression inhibitor promoting cartilage differentiation, and more specifically, to: a composition for promoting chondrocyte differentiation or treating cartilage diseases, containing a KLF10 gene expression inhibitor promoting cartilage differentiation and inhibiting the hypertrophy and dedifferentiation of chondrocytes; a cell therapeutic agent containing the composition; a method for promoting cartilage differentiation in bone marrow stem cells, comprising a step of expressing the composition in bone marrow stem cells; and a method for screening a chondrocyte differentiation promoter or a chondrocyte therapeutic agent.
    Type: Application
    Filed: December 30, 2014
    Publication date: January 19, 2017
    Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION F OUNDATION
    Inventors: Gun-Il IM, Jong-Min LEE
  • Patent number: 9522873
    Abstract: The present invention relates to a novel biphenyl derivative or a pharmaceutically acceptable salt thereof, a pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising the same as an active ingredient, and methods for treating inflammatory disease or autoimmune diseases with the pharmaceutical composition. Novel biphenyl derivatives according to the present invention promote the phagocytosis of macrophages and inhibit the chemotaxis to exhibit excellent inflammation terminating and anti-inflammatory effects and thus can be effectively used as therapeutic agents for inflammatory diseases or autoimmune diseases.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: December 20, 2016
    Assignee: Dongguk University Industry-Academic Cooperation Foundation
    Inventors: Chang Hoon Lee, Kyeong Lee
  • Patent number: 9516296
    Abstract: A system for extracting a 3D shape of a hot metal surface, includes: a light source unit emitting four types of light, i.e. two types of light each having different wave bandwidths that are different from a wave bandwidth emitted by a hot target object, and two other types of light having the same wave bandwidths as the above-described two types of light, respectively, so that the types of light having the same bandwidths are polarized in different directions so as not to interfere with one another; an image acquisition unit simultaneously emitting the four types of light, polarized from the light source, onto the target object so as to acquire 2D images of the target object; and an image processing unit using a photometric stereo technique so as to combine the 2D images acquired by the image acquisition unit and extract a 3D shape of the surface of the target object.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: December 6, 2016
    Assignee: Dongguk University Gyeongju Campus Industry-Academy Cooperation Foundation
    Inventor: Yu Jin Jang
  • Patent number: 9509932
    Abstract: An image sensor may include a comparator including a first input terminal configured to receive a reset signal, a second input terminal configured to receive an image signal, a third input terminal configured to receive a ramp signal configured to ramp in one direction, and an output terminal. The comparator may further include a switch circuit including a plurality of switches. The comparator may be configured to compare the reset signal with the ramp signal and output a first comparison signal through the output terminal according to a first arrangement of the switches in a reset phase and the comparator may be configured to compare the image signal with the ramp signal and output a second comparison signal through the output terminal according to a second arrangement of the switches in an image phase.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: November 29, 2016
    Assignees: Samsung Electronics Co., Ltd., Dongguk University Industry-Academic Cooperation Foundation
    Inventors: Jae Jung Park, Dae Yun Kim, Jae Young Bae, Min Kyu Song
  • Patent number: 9499787
    Abstract: The present invention relates to a method for differentiating stem cells into neurons, and is characterized in that stem cells are treated with a culture additive comprising lipoic acid, albumin, hydrocortisone, and insulin after culturing for differentiation into neurons. Since the neurons produced according to the method for producing neurons of the present invention express nestin, neuroD1, neuron-specific enolase (NSE), neurofilament (NF), tau, microtubule-associated protein 2 (MAP2), and doublecortin (DCX), just as normal mature neurons do, the neurons of the present invention can be effectively used in various therapeutic agents for neurons and as cell origins for an in vitro study system.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: November 22, 2016
    Assignee: Dongguk University Industry—Academic Cooperation Foundation
    Inventors: Jung Keug Park, Hee Hoon Yoon, Soo Yeon Kim, Young Kwon Seo
  • Publication number: 20160332980
    Abstract: The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
    Type: Application
    Filed: July 27, 2016
    Publication date: November 17, 2016
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kyeong LEE, Sei-Ryang OH, Kyung Seop AHN, Ok-Kyoung KWON, Doo-Young KIM, Hyung Won RYU, Jung Hee KIM, Xuezhen XU
  • Patent number: 9476083
    Abstract: The present invention relates to a two-dimensional code-type time-temperature indicator the color or shape of which changes in accordance with time and temperature conditions, and to a method for manufacturing the time-temperature indicator, to a quality guarantee system using the time-temperature indicator, and to a quality guarantee method using the quality guarantee system. The time-temperature indicator comprises: nanobeads containing a microorganism for generating lactic acids using nutrient components, an indicating agent for indicating the change in color by means of the generated lactic acids, an immobilization material for immobilizing the microorganism, the indicating agent, and the nutrient components; a base having a bonding layer; and a cover film.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: October 25, 2016
    Assignee: Dongguk University Industry-Academic Cooperation Foundation
    Inventors: Seung Ju Lee, Seung Won Jung
  • Patent number: 9447063
    Abstract: The present invention relates to a novel disubstituted adamantyl derivative or the pharmaceutically acceptable salts thereof, a method for preparing the same, and a pharmaceutical anticancer or antimetastasis composition comprising the same as an active ingredient. The disubstituted adamantyl derivative of the present invention suppressed accumulation of HIF-1?, inhibiting the expression of the metastasis related protein Twist dose-dependently. Thus, the disubstituted adamantyl derivative of the invention is effective in inhibiting the expressions of the metastasis related proteins, ?-catenin and RohA, and the EMT related genes such as MMP2 and MMP9, without cytotoxicity. Therefore, the disubstituted adamantyl derivative or the pharmaceutically acceptable salts thereof of the invention can be efficiently used as a pharmaceutical anticancer or antimetastasis composition.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: September 20, 2016
    Assignees: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Mi Sun Won, Kyeong Lee, Bo Kyung Kim, Hyun Seung Ban, Seohyun Son, Kyung-Sook Chung
  • Patent number: D790704
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 27, 2017
    Assignee: DONGGUK UNIVERSITY GYEONGJU CAMPUS INDUSTRY-ACADEMY COOPERATION FOUNDATION
    Inventor: Jae Jun Yang