Abstract: The present invention relates to new substituted pyrazolo[1,5-a]pyridine having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.

Abstract: A method for treatment of raw brines from desalination plants (6) having a total salt content greater than 60 g/l, wherein, inter alia, a magnesium ion-containing solution having a magnesium ion content greater than 1 g/l at a temperature between 75° C. and 100° C. is passed through a first vertical column (42) containing a bed packing of zeolite A (84) with a flow direction from top to bottom and the raw brine that is to be treated is passed at a temperature of 30° C. to 45° C. through this packed first column (42) in the direction of flow from top to bottom until the calcium ion concentration of the eluate leaving the first column (42) indicates a breakthrough of calcium ions through the bed of zeolite A (44).

Abstract: An optical position-measuring device includes a measuring standard as well as a scanning unit movable relative to it along at least one measuring direction, a scanning beam path being formed between the measuring standard and scanning unit and being used to generate displacement-dependent signals. A protective cap is disposed in a manner allowing movement along an axis perpendicular to the measuring-standard plane such that in at least one operating mode, the protective cap for the most part surrounds the scanning beam path between the scanning unit and measuring standard.

Abstract: A metal casting has a metal casting base body into which at least one metal insert body (1) is cast. The metal insert body has anti-twisting part-contours and is connected to the metal casting base body in a positively locking manner by the casting-in. To simplify the production of a stable metal casting, the metal insert body (1) has an elongate shape with a longitudinal axis and an outer mold contour with an unround cross section interrupted in the longitudinal direction by annular grooves (11-13) that fix the cast-in metal insert body (1) in the axial direction.

Abstract: An electric connecting module (12) for an electric component (10) of a motor vehicle (40) has a connecting section (22) with at least two electrical contacts (36). A connecting housing (24) has a connecting opening that can be connected to the connecting section (22). The connecting housing (24) has at least one cable opening (18) that opens laterally on the connecting housing (24) in relation to the connecting opening for routing electric connecting lines (14) through the connecting opening (18) and to connect them to the contacts (36). The connecting housing (24) can be connected to the connecting section (22) in different rotational positions to route the connecting lines (14) in different directions in relation to the electric component (10).

Abstract: A motor vehicle (1) has a body (4) and a sill (3) arranged between the wheel houses (5) on a longitudinal side of the vehicle. The sill (3) has a sill element (6) that is adjustable in the lateral direction between a first end position and a second end position. At least one protruding air guiding element (7,8) is arranged on the sill element (6).

Abstract: A filter device for the exchange of gas between the fuel tank for liquid fuel and an environment has a chamber sealed in a fluid-tight manner. A first port leads into the chamber for fluid connection to the fuel tank. A second port into leads the chamber for fluid connection to the environment. A granular filter material is in the chamber. The chamber is designed for optionally accommodating a monolithic filter element in addition to the granular filter material.

Abstract: The floor of a vehicle has two planar extruded profiles, located one on top of the other and having opposing T-shaped ribs rotated through 90 degrees with respect to one another. T-shaped recesses are introduced into ribs of one profile, and crosspieces on T-shaped ribs of the opposite extruded profile engaging in an interlocking manner. The extruded profiles are pushed into one another for connection, and a foam is introduced beforehand into the cavities between the ribs. The foam is foamed up so that the two extruded profiles are connected in an adhesively bonded manner.

Abstract: An evaluation unit is provided for processing images and/or image sequences of measurement areas (8, 10, 12, 14, 16, 18) that are detectable on a crash test vehicle (4). Transmitted images and/or image sequences from at least one measurement sensor are utilizable. Additionally, image fusion apparatus is provided to produce digital image fusion of images and/or image sequences as image data (38, 40) of the same measurement area (8, 10, 12, 14, 16, 18). An evaluation method, a measurement system for a crash test vehicle measurement and a method for performing a crash test vehicle measurement also are provided.

Abstract: A method for transmitting electrical power and first and second signals between a wall and a leaf pivotable relative to the wall. The method includes providing a leaf comprising an electric consumer and an electrical signal transmitter, providing a control and evaluation unit on a wall, providing a single power transmitting device, providing a first optocoupler, and providing a second optocoupler. The electrical actuating power and the electrical operating power are transmitted from the wall to the leaf in a galvanically isolated manner via the single power transmitting device. The first signals are transmitted from the leaf to the wall via the first optocoupler so as to regulate the electrical power supplied on the wall according to an actuating and operating power demand. The second signals are transmitted bidirectionally between the control and evaluation unit on the wall and the electric signal transmitter on the leaf via the second optocoupler.

Abstract: Device for fastening at least one PV module (1) to a roof which comprises a trapezoidal metal sheet (2) with a trapezoidal bead (3) with two oblique sides (4, 5) and an upper side (6), wherein the device comprises: exactly one holding plate (10) for fastening to one of the two oblique sides (4, 5), a supporting face (11), a holding-down element (12) for clamping the at least one PV module (1) against the supporting face (11), a threaded shaft (13) which is assigned a central shaft axis (S) and which is provided for actuating the holding-down element (12) in the direction of the supporting face (11), exactly one hinge joint (R, 14, 15) which is assigned a central axis of rotation (R) and by means of which the exactly one holding plate (10) and the threaded shaft (13) are rotatably coupled to one another and which has a joint pin (14) and a pin receptacle (15), wherein the threaded shaft (13) and the joint pin (14) are arranged perpendicular to one another in such a way that a common plane (E) results in which

Abstract: A protective arrangement for safety-relevant parts of a motor vehicle that are arranged in a supporting structure. The protective arrangement is provided between the safety-relevant part and the closest bumper. The protective arrangement has at least one protective element that is arched in the longitudinal direction of the motor vehicle toward the outside of the motor vehicle. The protective element is mounted directly or indirectly on the supporting structure via bearings that are configured such that a bearing action acts only in the longitudinal direction of the motor vehicle.

Abstract: The invention relates to a device and method for generating noise for a motor vehicle, having at least one sensing unit (101), which is designed to measure at least one operating signal (11) of the motor vehicle and to forward a basic signal (12) on the basis thereof to a tuning unit (102), wherein the tuning unit (102) is designed to convert the basic signal (12) by means of filtering and acoustic shaping to form a noise signal (13) and to forward the noise signal (13) to an amplifier unit (103), wherein the amplifier unit (103) is designed to amplify the noise signal (13) and to forward an amplified noise signal (14) to a converter unit (104), and wherein the converter unit (104) is designed to convert the amplified noise signal (14) into corresponding acoustic signals in order to generate noise.

Abstract: The present invention is directed to compositions and processes for their use that allow for the delivery of physiologically active agents, using a unique composition containing glycerin and triglycerides in the proper ratio. The composition functions by acting both as a humectant and occlusive agent attracting water, returning the skin surface to a smooth state and holding water and physiologically active agents in place. The presence of both hydrophobic and hydrophilic components of the current invention solubilize the physiologically actives into the complex matrix, keeping the actives on the skin and allowing them to penetrate the skin over time, thus delivering the actives to the blood stream.

Abstract: A mounting frame (20) for an electrically driven motor vehicle (10) has two frame beams (34, 36) oriented in a longitudinal direction (18) of the motor vehicle (10). An electric drive unit (22) for driving the motor vehicle (10) is mounted on the frame beams (34, 36), and has an electrical component (28) formed separately from the electric drive unit (22). The electrical component (28) is accommodated in a flexurally stiff housing (40) that is mounted on the mounting frame (34, 36). The frame beams (34, 36) form a frame arrangement which is open outwardly in the longitudinal direction (18), and the housing (40) of the electrical component (28) is mechanically fixedly connected to the two frame beams (34, 36) to form a closed frame section together with the frame beams (34, 36).

Abstract: A rear region of a motor vehicle has an underbody with at least one air-guiding element that is adjustable from a rest position into various operative positions. One operative position increases negative lift and another operative position reduces aerodynamic drag. The air-guiding element is adjustable into the individual operative positions via a central, transversely arranged pivot axis.

Abstract: An aqueous topical serum having stabilized bioactive L-ascorbic acid has a pH of from 3.4 to 3.8 and comprises from 10% to 18% by weight of L(+)-ascorbic acid, 0.2% by weight retinyl propionate, and from 0.005% to 0.5% by weight of a mixture selected from the group consisting of glabridin, silibinin and thyme.