Abstract: Aspects of the present appliction relate to pharmaceutical formulations comprising bendamustine or its pharmaceutically acceptable salts, isomers, racemates, enantiomers, hydrates, solvates, metabolites, polymorphs, and mixtures therof, suitable for phamaceutical use. Aspects further provide methods of producing stable bendamustine compositions.

Abstract: A drive train (1) of a motor vehicle has an internal combustion engine (2) with a crankshaft (6). A transmission (3) is connected downstream for driving at least one axle (5) of the motor vehicle. A starter generator (9) is attached to the crankshaft (6) of the internal combustion engine (2) via a spur gear mechanism (10). The spur gear mechanism (10) has a first drive train (11) with a switchable clutch (12) and a second drive train (13) with a switchable clutch or a freewheel (14) that is active during the starter mode of the starter generator (9). In a drive train of this type, the components for transmitting the torque of the starter generator (9) require only little space and, during starting, the crankshaft (6) of the internal combustion engine is decoupled from tensile forces and weights which would be observed when a belt drive is used.

Abstract: A pneumatic spring device with a housing (1) surrounding an air-filled annular chamber (2) and with a piston (3) sliding axially in the annular chamber (2), for the reduction or avoidance of flow noises, at least one cushion (K) made from metal wire netting being integrateable directly into the annular space (2) so as to be capable of throughflow.

Abstract: To avoid wind noises and to reduce soiling of mirror glass during travel in the rain, the exterior rear view mirror for a motor vehicle has a droplet channel in a first circumferential region of the mirror housing that includes the housing top and a separation edge in a second circumferential region on the housing bottom. The droplet channel and the separation edge overlap in a lateral region. Rain droplets that strike the mirror housing during travel flow both on the bottom housing side and on the top housing side toward the rear edge of the housing. Water droplets flowing on the bottom are collected by the separation edge and are blown away by the air flow which is directed down at the separation edge. On the housing top side, the droplets are collected by the droplet channel and conducted away laterally toward the housing bottom.

Abstract: A drive device for a hybrid vehicle, which has a first driven axle and a second driven axle, including: a first motor/generator unit, which is connected to the first driven axle; an internal combustion engine unit, which is connected in a rotationally fixed fashion to a differential/transmission unit which is connected to the rear axle; a second motor/generator unit, which is connected in a rotationally fixed fashion to the differential/transmission unit, parallel to the internal combustion engine unit; a clutch unit, which is designed to disconnect and connect a force flux between the differential/transmission unit and the second driven axle; and a control unit, which actuates the clutch unit, the internal combustion engine unit, the first motor/generator unit and the second motor/generator unit as a function of predefined operating states.

Abstract: A method is provided for operating a hybrid vehicle (1) having an internal combustion engine (2) and an electric machine (4) that can be used individually or jointly to drive at least one axle (9, 10) of the hybrid vehicle (1) by connecting a clutch (15), and having a regeneratable filter device that takes up fuel vapors from a fuel tank of the internal combustion engine (2). To improve the comfort in a purely electric driving mode and/or to improve the reproducible operation of a hybrid vehicle during a special exhaust gas test, in a purely electric driving mode in which the hybrid vehicle (1) is driven only by the electric machine (4), the internal combustion engine (2) is switched on with the clutch (15) open to regenerate the filter device.

Abstract: To hold loudspeakers of different sizes in an instrument panel of a motor vehicle, a holding plate with a cutout for inserting a first variant of a circular loudspeaker is arranged in the wall part of a defroster duct, and the holding plate can, by means of predetermined breaking points arranged at the edge in the direction of the wall part, be detached in order to obtain a further, larger cutout for inserting a second variant of a rectangular loudspeaker.

Abstract: A battery system with at least one cell having an adjacent temperature-equalizing structure that is provided alternately with the cells and is designed for a medium that carries heat and/or cold to pass through. The cells are individual cells (1, 1?, 1?), and the temperature-equalizing structures are conventional corrugated board (2a, 2b, 2c, 2d, 2e, 2?a, 2?b, 2?c, 2?d, 2?e) having two cover layers and at least one corrugation arranged between them for the air to pass through.

Abstract: A hybrid vehicle has a first drive apparatus for driving wheels on a first axle by an internal combustion engine and a second electrical drive apparatus with two electrical machines for driving wheels on a second axle. At least one electrical energy store can be discharged when the two electrical machines are operated as a motor and can be charged when the electrical machines are operated as a generator. The two electrical machines of the electrical drive apparatus are combined with a respectively associated gearbox in an electrical axle to drive the individually suspended wheels on the first axle via universally jointed shafts. Two electrical converters are associated respectively with the two electrical machines and are combined in one converter unit, such that a basic module has the mechanical link to a bodywork structure, the link to a cooling circuit and the electrical link to an electrical energy store.

Abstract: A drivetrain has at least one drive machine (2, 3) with a drive output shaft (6) that can be coupled via a transmission (10) to at least one drive wheel. The transmission (10) is mounted on the drive machine (2, 3) and has a planetary gear set (18). To reduce the expenditure for the development and/or manufacture of the drivetrain, the transmission (10) has different mounting positions rotated relative to the drive output shaft (6) of the drive machine (2, 3).

Abstract: The invention relates to pyrazole derivatives of formula I having pharmacological activity and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of pain.

Abstract: A method of matching medical images according to user-defined matches rules. In one embodiment, the matched medical images are displayed according user-defined display rules such that the matched medical images may be visually compared in manner that is suitable to the viewer's viewing preferences.

Abstract: A method for operating a tire pressure monitoring system of a motor vehicle, including a direct or indirect sensing device for sensing and outputting the pressure which is present in the motor vehicle tires. In order to assist the driver of a vehicle when inflating a tire, a loudspeaker, which is present on the motor vehicle, is used to transmit the current pressure value (pact) to the vehicle driver by a voice message. In this context, the voice message includes the current pressure values (pact) in increments of 0.1 bar. The loudspeakers, which are present, are the loudspeakers of the vehicle's own multimedia system or a loudspeaker of the vehicle's own alarm system.

Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.

Abstract: A device and method for cooling an axle differential of a motor vehicle includes an air-guiding plate for guiding the air stream under the motor vehicle. An air-guiding plate is provided for guiding the air stream under the motor vehicle.

Abstract: A device for separating solid particles from liquids includes a pressure vessel and one or more filter element registers having filter elements disposed in suspension on a horizontal filtrate discharge pipe. Each of the filter elements is formed from a substantially flat support mesh, a completely enclosed filter medium and spacers suspended therebetween. The support mesh is formed of rolled-flat mesh pipes that are smooth on an outside of the mesh pipes and, in an interior thereof, include longitudinal webs arranged to form channels that permit filtrate to flow to the horizontal discharge pipe.

Abstract: An internal combustion engine having a plurality of cylinders and an air intake system, with the air intake system formed from at least one distributor pipe, a plurality of intake pipes and at least one plenum, and with the plenum positioned between the distributor pipe and the intake pipes. Here, the combustion air is fed to the air intake system via an air guiding duct which opens out into the distributor pipe, with the charge pressure of the combustion air reduced between the outlet out of the compressor and the inlet into the combustion chamber. A distributor pipe length is dimensioned as a function of an equivalent distributor pipe diameter such that it is possible for a reduction in the charge pressure to be obtained within the air intake system by expansion taking place partially in the plenum in the respective intake pipe and/or within the distributor pipe.