Patents Assigned to DSM IP ASSETS
  • Patent number: 10337040
    Abstract: The invention relates to a process for the preparation of a fermentation product from lignocellulosic material, comprising the following steps: a) optionally, pretreatment of the lignocellulosic material, b) optionally, washing of the optionally pretreated lignocellulosic material, c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material using an enzyme composition comprising at least two cellulases and whereby the enzyme composition at least comprises LPMO, and optionally purifying the hydrolysed lignocellulosic material, d) fermentation of the hydrolysed lignocellulosic material to produce a fermentation product, and e) optionally, recovery of a fermentation product, wherein the amounts of formed hydrolysed oxidation products at the end of the enzymatic hydrolysis by the oxidation by LPMO of the lignocellulosic material containing cellulose and/or cello-oligosaccharides is kept between 3 to 80 g/kg glucan present in the lignocellulosic material by adding a s
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: July 2, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Loes Elizabeth Bevers, Rudy Francois Maria Jozef Parton, Michael Petrus Jozef Berkhout
  • Patent number: 10336675
    Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: July 2, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Igor Bendik, Piero Geotti-Bianchini, Marc Heidl, Eileen Jackson, Alexander Schlifke-Poschalko
  • Patent number: 10336853
    Abstract: There is described a low number average molecular weight (MN<10 kD) and high glass transition temperature (>75° C.) copolymer (optionally a solid grade oligomer (SGO)) that comprises (a) at least 20 wt-% of itaconate functional monomer(s), (b) not more than 40% of a hydrophilic monomer, preferably an acid functional monomer(s) in an amount sufficient to achieve an acid value from 65 to 325 mg KOH per g of solid polymer; (c) optionally not more than 70% of other monomers not being either (a) or (b), having a max content of vinyl aromatic monomer(s) of 40 wt-% and/or max content of methacrylate(s) of 40 wt-%; where the weight percentages of monomers (a), (b) and (c) are calculated as a proportion of the total amount of monomers in the copolymer being 100%.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: July 2, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Tijs Nabuurs, Yvonne Wilhelmina Smak, Gerardus Cornelis Overbeek
  • Patent number: 10327449
    Abstract: A variant polypeptide having alpha-amylase activity, wherein the variant has an amino acid sequence which, when aligned with the alpha-amylase comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue. Such a variant polypeptide may be used in the preparation of a baked product.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: June 25, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Rene Marcel De Jong, Hanna Elsabet Abbas, Evert Tjeerd Van Rij
  • Patent number: 10328011
    Abstract: Proline containing dipeptides are disclosed for up-regulating of genes involved in collagen fiber maturation and thus for revitalizing, strengthening and increasing the integrity of collagen fibers. These proline containing dipeptides are furthermore particularly suitable for improving the skin firmness, texture and elasticity as well as reducing the pore size and increasing skin moisturization.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: June 25, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Remo Campiche, Dominik Imfeld, Alexandre Rio
  • Patent number: 10328455
    Abstract: The invention relates to a one component heat-curable powder coating composition comprising a resin containing reactive unsaturations and wherein all said reactive unsaturations are carbon carbon double bonds connected directly to an electron withdrawing group, a thermal initiation system comprising a transition metal catalyst and a peroxide, wherein the peroxide is chosen from the group of peroxyesters, mono-peroxycarbonates and mixtures thereof and a co-crosslinker chosen from the group of vinylethers, vinylesters, vinylamides, itaconates, enamines and mixtures thereof.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: June 25, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johan F. G. A. Jansen, Jan Pieter Drijfhout
  • Patent number: 10329431
    Abstract: The invention relates to a one component heat curable powder coating composition comprising a resin containing reactive unsaturations and wherein all said reactive unsaturations are carbon carbon double bonds connected directly to an electron withdrawing group, a thermal initiation system comprising a peroxide chosen from the group of compounds represented by formula (1) wherein R1 and R2 each independently stand for an optionally substituted alkyl of 1 to 30 C-atoms, wherein the 1 to 30 C-atoms do not include the C-atoms of the substituents or for an optionally substituted aryl of 6 to 18 C-atoms, wherein the 6 to 18 C-atoms do not include the C-atoms of the substituents, and a co-crosslinker chosen from the group of vinylethers, vinyletherurethanes, vinylesters, vinylamides, itaconates, enamines, vinylureas and mixtures thereof.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 25, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johan F.G.A. Jansen, Jan Pieter Drijfhout
  • Patent number: 10316306
    Abstract: The present invention relates to an alpha amylase enzyme and to its use in the food, feed and non-food industry.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: June 11, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Hanna Elisabet Abbas, Jan Metske Van Der Laan, Johannes Gustaaf Ernst Van Leeuwen
  • Patent number: 10316305
    Abstract: The invention relates to a polypeptide having hemicellulase activity. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional protein and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: June 11, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Alrik Pieter Los, Rene Marcel De Jong, Maaike Appeldoorn
  • Patent number: 10316055
    Abstract: The present invention relates to a method of purification of compound of formula (I) which comprises the step of crystallization of compound of formula (I) from a composition comprising the compound of formula (I) and the compound of formula (II) and a specific solvent system containing ethanol, 1-propanol, 2-propanol, 2-methyl-1-propanol, 1-butanol or 2-butanol.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: June 11, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jan Schuetz, Ralph Waechter
  • Patent number: 10315380
    Abstract: The invention relates to a process for the manufacture of a multilayer material sheet comprising unidirectional high performance fibers, the process comprising the steps of positioning the fibers in a parallel fashion, consolidation of the fibers to obtain a monolayer, stacking at least two monolayers such that the fiber direction in one monolayer is at an angle ? to the direction of the fibers in an adjacent monolayer and fixation whereby the stack of at least two monolayers is subjected to a pressure and temperature treatment for a duration of a least 2 seconds, followed by cooling the stack under pressure to a temperature of 120° C. or lower. The invention furthermore relates to the multilayer material sheet obtainable with the process according to the invention. This multilayer material sheet has a reduced uptake of liquids.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: June 11, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Koen van Putten, Johannes Maria Mathias Wilms, Ernst Jan van Klinken, Harm van der Werff, Leonard Josef Arnold Nielaba, Roelof Marissen
  • Patent number: 10308920
    Abstract: The invention provides hydrolases, polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides, e.g., enzymes, having a hydrolase activity, e.g., an esterase, acylase, lipase, phospholipase (e.g., phospholipase A, B, C and D activity, patatin activity, lipid acyl hydrolase (LAH) activity) or protease activity, including thermostable and thermotolerant hydrolase activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The hydrolase activities of the polypeptides and peptides of the invention include esterase activity, lipase activity (hydrolysis of lipids), acidolysis reactions (to replace an esterified fatty acid with a free fatty acid), transesterification reactions (exchange of fatty acids between triglycerides), ester synthesis, ester interchange reactions, phospholipase activity and protease activity (hydrolysis of peptide bonds).
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: June 4, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Uwe T. Bornscheuer, David Weiner, Tim Hitchman, Jonathan Lyon, Sirirung Wongsakul
  • Patent number: 10302819
    Abstract: The invention relates to a process of making an anti-reflective coating composition comprising the steps of 1) preparing an oil-in-water emulsion by mixing an apolar organic compound A; a cationic addition copolymer C as emulsion stabilizer; and aqueous medium of pH 2-6; at a mass ratio C/A of 0.1 to 2, to result in 1-50 mass % (based on emulsion) of emulsified droplets of average particle size 30-300 nm; and 2) providing an inorganic oxide shell layer to the emulsified droplets by adding to the emulsion obtained in step 1) at least one inorganic oxide precursor, to result in organic-inorganic core-shell nano-particles with mass ratio core/shell of from 0.2 to 25. An advantage of this process is that the dispersion of nano-particles obtained is stable under different conditions, and allows altering its concentration and solvent system, and addition of different binders and auxiliary components.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: May 28, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Michael Alphonsus Cornelis Johannes Van Dijck, Hermanus Adrianus Langermans, Jacobus Adriaan Antonius Vermeulen
  • Patent number: 10294467
    Abstract: The present invention relates to a polypeptide having proline-specific endoprotease activity, wherein the polypeptide has less than 70% residual activity when the polypeptide has been kept at a temperature of 65° C. for 15 min. The invention further relates to a polypeptide having proline-specific endoprotease activity comprising an amino acid sequence according to SEQ ID NO: 1, wherein SEQ ID NO: 1 comprises at least one amino acid substitution selected from the group consisting of P469A, P469C, P469D, P469E, P469F, P469G, P469H, P469I, P469K, P469L, P469M, P469N, P469Q, P469R, P469S, P469T, P469V, P469W, P469Y, a nucleic acid encoding a polypeptide having proline-specific endoprotease activity, a method of making a variant polypeptide having proline-specific endoprotease activity, a recombinant host cell and a method of producing the polypeptide and a process for the preparation of a food or feed product wherein the polypeptide is used.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: May 21, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jan Metske Van Der Laan, Peter Jozef Ida Van De Vondervoort, Chantal Christis, Martine Spaans, Angela De Bruine-Paulus
  • Patent number: 10287610
    Abstract: The invention relates to an integrated process for alcohol production and organic acid production from lignocellulosic material.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: May 14, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventor: Johannes Petrus Smits
  • Patent number: 10280532
    Abstract: Suture containing filaments of ultra-high molecular weight polyethylene (UHMwPE), characterized in that the suture contains a multi-filament yarn that is obtained by a process comprising the steps of: a) Providing a mixture containing UHMwPE, a spinning solvent and a pigment b) Spinning a multi-filament yarn from the mixture by the gel spinning process.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: May 7, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Joseph Arnold Paul Maria Simmelink, Claudia C. Vaz
  • Patent number: 10273507
    Abstract: The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: April 30, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Maria Bernedina Elizabeth Jonkers, Paul Klaassen, Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Rene Marcel De Jong
  • Patent number: 10273519
    Abstract: The present invention relates to a method for the production of a diterpene or a glycosylated diterpene, which method comprises: a. fermenting a recombinant microorganism of the genus Yarrowia in a suitable fermentation medium at a temperature of about 29° C. or higher, wherein the microorganism comprises one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity and whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol; and b. recovering the diterpene or glycosylated diterpene.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: April 30, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Nicolette Jasmijn Broers, Viktor Marius Boer, Adam G. Lawrence
  • Patent number: 10266676
    Abstract: The invention relates to a plastic engine cover, as well as to a process for making the plastic engine cover and to an engine comprising the plastic engine cover. The plastic engine cover is made of a glass fiber reinforced thermoplastic polymeric material comprising a polyamide with units derived from terephthalic acid and from diamino butane.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: April 23, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: James Beam Conkey, Peter Clinton Schmieg
  • Patent number: 10266365
    Abstract: The invention concerns an improved yarn package and a method winding a package of high Young's modulus yarn. The package has a low normalized standard deviation in unwinding tension and hence is very suitable for converting into a range of yarn constructions and particularly medical products.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: April 23, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Evert Florentinus Florimondus De Danschutter, Herbert Rabe, Carsten Goerke