Patents Assigned to DSM IP ASSETS
  • Patent number: 10144939
    Abstract: The invention relates to a process for the preparation of a fermentation product from lignocellulosic material, comprising the following steps: a) optionally, pre-treatment of the lignocellulosic material, b) optionally, washing of the optionally pretreated lignocellulosic material, c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material using an enzyme composition comprising at least two cellulases and whereby the enzyme composition at least comprises LPMO, and optionally purifying the hydrolyzed lignocellulosic material, d) fermentation of the hydrolyzed lignocellulosic material to produce a fermentation product, and e) optionally, recovery of a fermentation product, wherein oxygen is consumed in amounts corresponding to between 20 and 5000 mmol molecular oxygen per kg glucan present in the lignocellulosic material, the oxygen is added after the pretreatment and before and/or during the enzymatic hydrolysis of the lignocellulosic material, preferably in an a
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: December 4, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
  • Patent number: 10131923
    Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolyzed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: November 20, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
  • Patent number: 10125345
    Abstract: A centrifuge device is provided for the sizing and separation of constituents of a biologic mixture, e.g., adipose tissue. The device provides for the mechanical breaking down of the fibrous structure in the tissue by centrifugation causing the tissue to pass through a mesh element, or a sizing helix, or an extrusion element, whereupon the material is reduced to a slurry. This processed material may then be separated by centrifugation into its constituents, in order to harvest the fraction containing the multipotent cells. These multipotent cells may be utilized for various medical procedures to stimulate healing and tissue regeneration.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: November 13, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John E. Nash, William T. Fisher, Gino Bradica
  • Patent number: 10123972
    Abstract: The present disclosure relates to fibers implantable in the body of a human or animal and processes for manufacturing such a fiber. The fiber undergoes a reduction in surface area to volume ratio of a factor of 1.05-10 upon injection in the human or animal body. In an embodiment, a process for manufacturing a fiber comprises extruding a biodegradable polymer into a fiber capable of fitting in a syringe needle of at least 25 Gauge, and cooling the fiber below its dry glass transition temperature while the fiber is under tension.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: November 13, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: Astrid Franken, George Mihov, Jens Christoph Thies
  • Patent number: 10117449
    Abstract: The present invention relates to a process for the production of extruded formulations (=extrudates) comprising dispersion droplets, to such formulations as well as to the use of such formulations in food, feed, personal care applications.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 6, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Petrus Henricus Maria Elemans, Adrian Willem Meesen, Alexandra Teleki, Bruno Leuenberger
  • Patent number: 10118998
    Abstract: Processes for producing an (ultra) high molecular weight polyethylene (HMWPE) article include incorporating into the HMWPE resin a Hindered Amine Light Stabilizer (HALS) and cross-linking the (U)HMWPE during or after molding the (U)HMWPE resin.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: November 6, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Harold Jan Smelt, Pieter Gijsman, Martin Van Duin
  • Patent number: 10112356
    Abstract: The invention relates to a curved product, and in particular an armor product. The armor product is produced by a filament winding process in which a plurality of reinforcing elements in the form of fibers and/or tapes are impregnated with a polymer matrix and wound onto a mandrel. The polymer matrix comprises a solution and/or dispersion of a polymer in a carrier fluid, which carrier fluid is at least partly evaporated during and/or after winding. The armor product comprises a high amount of reinforcing elements with respect to the total mass of the product.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: October 30, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Roelof Marissen, Lucas Van Den Akker, Sotiris Koussios, Hen Hoefnagels
  • Patent number: 10113039
    Abstract: The invention relates to a process for producing shaped articles comprising the steps of: —compounding a polymer composition (A) containing a polyamide, a halogen-free melamine based flame retardant and at most 15 wt. % of glass fibers into pellets, compounding a polymer composition (B) containing a polyamide, more than 15 wt. % of glass fibers, and not containing halogen-free melamine based flame retardant into pellets, —producing a mixture comprising the pellets of polymer composition (A) and (B), —molding the mixture comprising the pellets of polymer composition (A) and (B) into shaped articles.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: October 30, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Hoekstra, Rui Zhang
  • Patent number: 10100461
    Abstract: Treated HPPE yarns include elemental metal which forms a layer that adheres to the surface of the HPPE yarn and covers at least partly the surface of the HPPE yarn. The elemental metal is deposited onto the outer surface of a HPPE yarn via sputtering, preferably plasma sputtering. Articles comprising the treated HPPE yarn, a device comprising the treated HPPE yarn or the article as well as processes for preparing the treated HPPE yarn or treated HPPE yarn structure or treated HPPE yarn configuration and use of the treated HPPE yarn or an article or a device comprising the treated HPPE yarn for automotive applications, marine applications, aerospace applications, medical applications, defense applications, sports/recreational applications, architectural applications, clothing applications, bottling applications, machinery applications are also disclosed.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: October 16, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Claudia Maria Vaz, Gerardus Aben, Edith Elisabeth Van Den Bosch, Christiaan Henri Peter Dirks, Paulus Johannes Hyacinthus Marie Smeets
  • Patent number: 10099193
    Abstract: The invention relates to a method of making hybrid organic-inorganic core-shell nano-particles, comprising the steps of a) providing colloidal organic particles comprising a synthetic polyampholyte as a template; b) adding at least one inorganic oxide precursor; and c) forming a shell layer from the precursor on the template to result in core-shell nano-particles. With this method it is possible to make colloidal organic template particles having an average particle size in the range of 10 to 300 nm; which size can be controlled by the comonomer composition of the polyampholyte, and/or by selecting dispersion conditions. The invention also relates to organic-inorganic or hollow-inorganic core-shell nano-particles obtained with this method, to compositions comprising such nano-particles, to different uses of said nano-particles and compositions, and to products comprising or made from said nano-particles and compositions, including anti-reflective coatings and composite materials.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: October 16, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Nanning Joerg Arfsten, Roberto Arnoldus Dominicus Maria Habets, Michael Alphonsus Cornelis Johannes Van Dijck
  • Patent number: 10100320
    Abstract: The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least 75% sequence identity to the amino acid sequence set out in SEQ ID NO: 2 and wherein the nucleotide sequence is heterologous to the host. A cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: October 16, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Rene Marcel De Jong
  • Patent number: 10100344
    Abstract: The present invention relates to a mutant microbial host cell which is deficient in the production of the AgsE protein or in the production of an homologous thereof if compared with a parent microbial host cell which has not been modified and measured under the same conditions. It has been surprisingly found that when the mutant microbial host cell according to the invention is used in a method to produce a compound of interest, for example an enzyme, an improved yield of said compound is obtained if compared to a method in which a parent host cell which has not been modified is used when measured under the same conditions.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: October 16, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Noël Nicolaas Maria Elisabeth Van Peij, Martina Beishuizen, Peter Jozef Ida Van De Vondervoort
  • Patent number: 10093914
    Abstract: The present invention relates to eukaryotic cells which have the ability to isomerize xylose directly into xylulose. The cells have acquired this ability by transformation with nucleotide sequences coding for a xylose isomerase that has one or more specific sequence elements typical for isomerases having the ability of functional expression in yeasts, such as e.g. xylose isomerases obtainable from a bacterium of the genera Clostridium and Fusobacterium or a tunicate form the genus Ciona. The cell preferably is a yeast or a filamentous fungus, more preferably a yeast is capable of anaerobic alcoholic fermentation.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: October 9, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Johannes Adrianus Maria De Bont
  • Patent number: 10087475
    Abstract: The disclosure relates to a process for the preparation of a sugar product from lignocellulosic material, comprising the following steps: a) optionally, pretreatment of the lignocellulosic material; b) optionally, washing of the optionally pretreated lignocellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material in a hydrolysis reactor using an enzyme composition comprising at least two cellulase; and d) optionally, recovery of a sugar product; wherein during the enzymatic hydrolysis oxygen-containing gas is added to the lignocellulosic material in the hydrolysis reactor and wherein part of the oxygen-containing gas, added to the lignocellulosic material, is gas originating from the headspace of the reactor, preferably during part of the time of the enzymatic hydrolysis less oxygen is added to the lignocellulosic material compared to the other part of the time of the enzymatic hydrolysis, or preferably during part of the time of the enzymatic
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: October 2, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout, Joseph Johannes Maria Hofmeester
  • Publication number: 20180273929
    Abstract: The present invention relates to a polypeptide having asparaginase activity selected from the group consisting of: (i) a polypeptide having an amino acid sequence comprising the mature polypeptide sequence of SEQ ID NO: 1; (ii) a polypeptide comprising an amino acid sequence that has at least 50% sequence identity with the mature polypeptide sequence of SEQ ID NO: 1; (iii) a polypeptide encoded by a nucleic acid comprising a sequence that hybridizes under medium stringency conditions to the complementary strand of the mature polypeptide encoding sequence of SEQ ID NO: 2; and (iv) a polypeptide comprising an amino acid sequence encoded by a nucleic acid that has at least 50% sequence identity to the mature polypeptide coding sequence of SEQ ID NO: 2. The polypeptide may be used in the preparation of a food product.
    Type: Application
    Filed: September 16, 2016
    Publication date: September 27, 2018
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jan Metske VAN DER LAAN, Siew-loon OOI, Aloysius Wilhelmus Rudolphus Hubertus TEUNISSEN, Maarten Hotse WILBRINK
  • Patent number: 10081797
    Abstract: The present invention relates to novel hydroxylases, nucleic acid sequences coding therefore, expression constructs and vectors comprising these sequences, microorganisms transformed therewith, processes for the microbiological hydroxylation of isoprenoids, for example processes for converting beta-carotene into beta-cryptoxanthin and zeaxanthin, or canthaxanthin into astaxanthin.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: September 25, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Christopher Farrell, Maria Mayorga, Bastien Chevreux
  • Patent number: 10076485
    Abstract: The invention relates to hair care compositions comprising an effective amount of a condensation polymer having at least one, optionally quaternized or protonated, dialkylamide end-group connected through the polymer backbone to a unit derived from an alkylamide, the connection comprising at least one ester linkage.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: September 18, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Raphael Beumer, Franciscus Derks, Christine Mendrok-Edinger
  • Patent number: 10076588
    Abstract: The invention relates to an elongate surgical repair product comprising a cable of which bending stiffness can be lowered, which fibrous member is a heat-set cable comprising at least 50 mass % of high-performance polyethylene yarn. The product shows very high tenacity, combined with a relatively high initial bending stiffness that is significantly reduced upon bending or flexing the member, without significant dimensional change; and allows both easy and well-controlled handling and good knot tying characteristics. The invention also relates to a method of making said elongate product.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: September 18, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Carina S Snijder, Rogier Oosterom, Christiaan H. P. Dirks
  • Patent number: 10077435
    Abstract: The invention relates to a host cell comprising at least four different heterologous polynucleotides chosen from the group of polynucleotides encoding cellulases, hemicellulases and pectinases, wherein the host cell is capable of producing the at least four different enzymes chosen from the group of cellulases, hemicellulases and pectinases, wherein the host cell is a filamentous fungus and is capable of secretion of the at least four different enzymes. This host cell can suitably be used for the production of an enzyme composition that can be used in a process for the saccharification of cellulosic material.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: September 18, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Alrik Pieter Los, Cornelis Maria Jacobus Sagt, Margot Elisabeth Francoise Schooneveld-Bergmans, Robbertus Antonius Damveld
  • Patent number: 10072179
    Abstract: The invention relates to a vinyl functionalized urethane resin (VFUR) useful as a curing agent in thermosetting powder coating compositions, a process for making said vinyl functionalized urethane resin, a vinyl functionalized urethane resin composition (VFURC) useful as a curing agent in thermosetting powder coating compositions, a process for making vinyl functionalized urethane resin composition, a thermosetting powder coating composition (TPCC), a process for the preparation thereof, a cured thermosetting powder coating composition, processes for coating an article with said thermosetting powder coating composition and an article coated with said thermosetting powder coating composition as well as uses of the vinyl functionalized urethane resin or of the vinyl functionalized urethane resin composition or of the thermosetting powder coating composition or of the articles having coated and cured thereon said thermosetting powder coating composition.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: September 11, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventor: Jan Pieter Drijfhout