Patents Assigned to DSM
  • Cosmetic Composition Containing Protein Hydrolysates
    Publication number: 20080063674
    Abstract: The invention provides cosmetic compositions comprising a protein hydrolysate and a cosmetically acceptable excipient, wherein the protein hydrolysate has a high content of peptides with a terminal proline.
    Type: Application
    Filed: June 17, 2005
    Publication date: March 13, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Juergen Vollhardt, Philippe Maillan
  • Microbial production of vitamin C
    Patent number: 7341854
    Abstract: The present invention provides a process for the production of vitamin C from different substrates like D-sorbitol, L-sorbose, L-sorbosone or L-gulose using a microorganism selected from the group consisting of Gluconobacter oxydans DMS 4025 (FERM BP-3812), a microorganism belonging to the genus Gluconobacter and having identifying characteristics of G. oxydans DSM 4025 (FERM BP-3812) and mutants thereof.
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: March 11, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Tatsuo Hoshino, Teruhide Sugisawa
  • Continuous process for preparing caprolactam
    Patent number: 7339056
    Abstract: The invention relates to a continuous process for preparing caprolactam by Beckmann rearrangement of cyclohexanone oxime, said process comprising a) feeding (i) oleum and (ii) cyclohexanone oxime into a first reaction mixture comprising caprolactam, sulfuric acid and SO3, b) feeding (iii) a portion of the first reaction mixture and (iv) cyclohexanone oxime into a second reaction mixture comprising caprolactam, sulfuric acid and SO3, c) withdrawing a portion of the second reaction mixture, wherein the process further comprises obtaining the cyclohexanone oxime that is fed to the reaction mixtures by: 1) preparing an organic medium comprising cyclohexanone oxime dissolved in an organic solvent 2) separating, by distillation, cyclohexanone oxime from said organic medium.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: March 4, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Joannes Albertus Wilhelmus J. A. W. Lemmens, Frank F. Mostert, Theodorus Maria T. M. Smeets
  • Polyester oligomers
    Patent number: 7335718
    Abstract: The present invention provides oligomers having a backbone and one or more curable groups. The backbone comprises a polyester that is prepared from, inter alia, one or more polyalkylesters.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: February 26, 2008
    Assignee: DSM IP Assets B.V.
    Inventor: Matthew Terwillegar
  • Encapsulated Cosmetic Materials
    Publication number: 20080031909
    Abstract: Cosmetic materials, e.g., sunscreen agents are encapsulated by means of a compound of the formula (I) where X is O or NR5; EWG is an electron-withdrawing group; R1, R2, R3, R5 are equal to an H, alykl, cycloalkyl, aryl, or heterocyclic group; or R1, R2 and R5 or R1, R2 and R3 together form a heterocyclic group; and wherein at least one NH or NH2 group, attached to an electron-attracting atom or to an atom that is connected to electron-attracting atom or group such as oxygen, nitrogen and sulphur, is present.
    Type: Application
    Filed: November 30, 2005
    Publication date: February 7, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Rudolfus Van Benthem, Alexander Poschalko, Juergen Vollhardt
  • Manufacture of isoflavones
    Patent number: 7326797
    Abstract: A process for manufacturing a hydroxylated isoflavone of the formula (I) given in the description comprises re-acting an appropriately substituted 2-hydroxydeoxybenzoin of the formula (II), also given in the description, with a formic acid anhydride of the formula HCOOCOR3, wherein R3 signifies C2-20-alkyl or various other groups as given in the description, in presence of a base or in a solvent which acts as a base, and if necessary promoting the ensuing hydrolysis of the so-produced acylated form of the hydroxylated isoflavone of the formula I by acidification. Of particular interest as products of this process are the 5,7dihydroxyisoflavones, e.g. genistein (5,7,4?-trihydroxyisoflavone). Isoflavones display many useful biochemical effects.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: February 5, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Bruno Burdet, August Ruettimann
  • Method for Production of a Compound in a Eukaryotic Cell
    Publication number: 20080026421
    Abstract: The present invention relates to a eukaryotic cell containing peroxisomes that are capable to fuse with a membrane-structure of the cell involved in the secretory pathway of the cell. In this way, the eukaryotic cell is able to release the peroxisomal content outside the cell. The invention also relates to a method for production of a compound of interest in said eukaryotic cell wherein said compound of interest is present in the peroxisome of the cell. Said compound of interest will accumulate in the peroxisome by a signal promoting peroxisome localisation. Preferred host cells are filamentous fungal cells.
    Type: Application
    Filed: October 13, 2005
    Publication date: January 31, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Cornelis Sagt, Petrus Johannes Fredrik Haaft, Johannes Hendrik Winde, Panagiotis Sarantinopoulos
  • Fixing Device For Clamping The Ends Of A Surgical Cable Used For Fixing Bone Parts
    Publication number: 20080027440
    Abstract: Fixing device comprising (I) a surgical cable (16) having a first and a second end and (II) at least a first (2) and a second (4) fixing plate having a first (6) resp. second (8) central hole and a first (10) resp. second (12) ring surrounding said first resp.
    Type: Application
    Filed: January 27, 2005
    Publication date: January 31, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Roelof Marissen, Karel J. Wetzels
  • Genes encoding novel proteolytic enzymes
    Patent number: 7323327
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: January 29, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Luppo Edens, Albertus Van Dijk, Philipp Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang
  • Process for the manufacture of tocyl and tocopheryl acylates
    Patent number: 7321053
    Abstract: A process for the manufacture of a tocyl acylate or a tocopheryl acylate comprises reacting tocol or a tocopherol with an acylating agent in the presence of a solid heterogeneous Brönsted acid catalyst, said catalyst being an inorganic Brönsted acid on a solid carrier material which comprises silicon dioxide, titanium dioxide or both silicon dioxide and titanium dioxide, or being an organofunctional polysilonaxe featuring sulpho groups, the solid heterogeneous Brönsted acid catalyst further featuring a BET surface area from about 10 m2/g to about 800 m2/g and a pore volume from about 0.1 ml/g to about 2.0 ml/g. The main commercial form of vitamin E, being (all-rac)-?-tocopheryl acetate, can be manufactured by acylation of (all-rac)-?-tocopherol according to this process.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: January 22, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Werner Bonrath, Lisa Giraudi
  • Process for the preparation of methylheptenone
    Patent number: 7319172
    Abstract: Methylheptenone (2-methyl-2-hepten-6-one) is prepared by reacting 2-methyl-3-buten-2-ol with isopropenyl methyl ether in the presence of hydrogen tris(oxalato)phosphate or hydrogen bis(oxalato)borate.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: January 15, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Fabrice Aquino, Werner Bonrath, Aljosa Crevatin
  • Use Of Plants, Plant Extracts And Nature-Identical Components From Plants To Affect The Rumen Fermentation And To Improve The Energy And Protein Retention Of Ruminants
    Publication number: 20080008774
    Abstract: Use of an plant materials, plant extracts or nature-identical components selected from Lonicera japonica, Gentiana asclepidea, Gentiana lutea, Eugenia caryophyllata, Bellis perennis, Olea europaea, Symphytum officinale, Carduus pycnocephalus, Paeoniae alba radix, Populus tremula, Prunus avium, Salix caprea, Rheum nobile, Helianthemum canum, Arctostaphylos uva-ursi, Peltiphyllum peltatum, Epilobium montanum, Knautia arvensis, Latuca sativa and Urtica dioica and extracts thereof, and &bgr;-myrcene to affect the rumen fermentation and to increase the availability of energy and nitrogen source for a ruminant.
    Type: Application
    Filed: April 15, 2005
    Publication date: January 10, 2008
    Applicants: DSM IP ASSETS B.V., ALL-TECHNOLOGY IRELAND LTD.
    Inventors: Klaus Becker, Cepta Duffy, Ellen Hoffmann, Riccardo Losa, Fergus Mould, Stefan Muetzel, Lopez Secundino, Natascha Selje, Robert Wallace
  • Expression cloning in filamentous fungi
    Publication number: 20080009006
    Abstract: Methods are provided for isolation of DNA sequences encoding proteins with properties of interest by means of expression cloning in filamentous fungal host cells. The isolated DNA sequences are useful in processes for producing the proteins of interest.
    Type: Application
    Filed: February 20, 2007
    Publication date: January 10, 2008
    Applicant: DSM N.V.
    Inventors: Johannes Maarten Van Den Brink, Gerardus Cornelis Maria Selten, Johannes Petrus Theodorus Wilhelmus Van Den Hombergh
  • Process for the production of a shaped article
    Patent number: 7311963
    Abstract: The invention relates to a process for the production of a shaped article comprising the compression of one or more fiber layers containing polyolefin fibers. The invention also relates to shaped articles obtainable with the process according to the invention and their use in anti-ballistic applications. In the process according to the invention the fiber layers contain 0.02 to 25 wt. % of a solvent for the polyolefin. The shaped articles obtained have an improved anti-ballistic quality.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: December 25, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Floribertus C. H. Mokveld, Jean H. M. Beugels
  • Process for the production of (?)-epigallocatechin gallate
    Patent number: 7312199
    Abstract: A process is provided for making (?)-epigallocatechin gallate (EGCG) by subjecting a green tea extract to chromatography on a macroporous polar resin, eluting EGCG from the resin with a polar elution solvent, optionally concentrating the eluate, optionally regenerating the resin by desorbing the remaining catechins, and optionally concentrating the desorbed catechins.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: December 25, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: David Carl Burdick, Heinz Egger, Andrew George Gum, Ingo Koschinski, Elena Muelchi, Isabelle Prevot-Halter
  • Aerobic fermentation method
    Patent number: 7309599
    Abstract: A method and apparatus for effectively aerating large-scale cultures of microorganisms is disclosed.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: December 18, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Pieter Marinus Van Den Broecke, Deodorus Jacobus Groen, Hendrik Jan Noorman
  • Protein hydrolysates enriched in peptides having a carboxy terminal proline residue
    Patent number: 7309595
    Abstract: The present invention provides An isolated polypeptide which has proline specific endoprotease activity, selected from the group consisting of:(a) a polypeptide which has an amino acid sequence which has at least 40% amino acid sequence identity with amino acids 1 to 526 of SEQ ID NO:2 or a fragment thereof;(b) a polypeptide which is encoded by a polynucleotide which hybridizes under low stringency conditions with (i) the nucleic acid sequence of SEQ ID NO:1 or a fragment thereof which is at least 80% or 90% identical over 60, preferably over 100 nucleotides, more preferably at least 90% identical over 200 nucleotides, or (ii) a nucleic acid sequence complementary to the nucleic acid sequence of SEQ ID NO:1.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: December 18, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Petrus Jacobus Theodorus Dekker, Luppo Edens, Robertus Antonius Mijndert Van Der Hoeven, Linda De Lange
  • Process for treating an aqueous medium containing phosphate, cyclohexanone and cyclohexanone oxime
    Patent number: 7309801
    Abstract: The invention relates to a process for treating an aqueous medium containing (i) phosphate and (ii) cyclohexanone and/or cyclohexanone oxime, said process comprising: feeding the aqueous medium to a stripping zone; passing steam through the aqueous medium in the stripping zone; and discharging a vapor stream from said stripping zone; wherein the joint content cyclohexanone and cyclohexanone oxime in the aqueous medium entering the stripping zone is less than 0.08 wt. %.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: December 18, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Arno Benneker, Henk Oevering, Johannes Antonius Leonardus Brouwers
  • Apparatus and method to locate an object
    Patent number: 7308141
    Abstract: Method and arrangement to locate an object with a predetermined number of marks, the arrangement comprising a light source, a sensor and a processor, by means of the following steps:—illuminating the object with the light source;—receiving an image of the object and generate image pixel data including image pixel locations and image pixel intensities for each image pixel location with said sensor;—receiving the image pixel data and storing them in a memory;—comparing said image pixel intensities with a predetermined threshold;—determining object position based on said comparing;—using a digital match mask that corresponds with said object with said marks;—finding a best match between said digital match mask and said object on said object position;—determining mark positions within said object position from said best match.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: December 11, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Pieter Cornelis Langeveld, Karl Heinrich Van Hemert, Johannes Hendrik Pieter Machiel Kerkhof, Jacobus Stark
  • Method for Screening and Selecting Enzymes
    Publication number: 20070264670
    Abstract: The present invention relates to a method for identifying an enzyme of interest comprising screening a set of candidate enzymes on an application matrix, preferably on at least a medium throughput level, and selecting enzymes for their ability to produce a functionality change in the application matrix. In the application matrix screening method of the invention it is not necessary to define the enzyme activity to be screened prior to applying the screening method.
    Type: Application
    Filed: June 30, 2005
    Publication date: November 15, 2007
    Applicant: DSM IP Assets B.V.
    Inventors: Albertus Van Dijk, Marcellis Wilhelmus Van Tilborg, Jort Gerritsma, Maurien Olsthoorn, Baukje Folkertsma, Ilja Westerlaken