Patents Assigned to DSM
  • Patent number: 7371547
    Abstract: Disclosed is a mutant of a recombinant microorganism of the genus Sinorhizobium capable of producing vitamin B6 having a recombinant plasmid with pdxJ gene that acquired histidine requirement of glycine resistance, or its combination thereof.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: May 13, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Tatsuo Hoshino, Yoichiro Nagatani, Keiko Ichikawa, Masaaki Tazoe
  • Patent number: 7371581
    Abstract: We describe a process for the monitoring of contaminant removal during the purification process of a pharmaceutical product produced by a host cell, wherein at least two different samples taken during the purification process of the pharmaceutical product are incubated with at least one protein biochip array and contaminants in the samples bound to the protein biochip array are subsequently detected. Preferably samples are taken before the first purification step and after each subsequent purification step.
    Type: Grant
    Filed: May 1, 2003
    Date of Patent: May 13, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Maria Gerarda Wilhelmina Gunnewijk, Jose Manuel Coco Martin
  • Publication number: 20080103226
    Abstract: The invention relates to a radiation curable composition comprising from about 50 wt % to about 70 wt % of a cycloaliphatic diepoxide, from about 5 wt % to about 15 wt % of a polyol, from about 5 wt % to about 15 wt % of an oxetane, from about 10 wt % to about 20 wt % of an aromatic diacrylate, a radical photoinitiator and a cationic photoinitiator. The invention further relates to a process for making a three dimensional article from the resin composition of the invention, to the three-dimensional article itself and to the use of the composition of the invention.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 1, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventor: Jigeng Xu
  • Patent number: 7364678
    Abstract: The invention relates to a process for making a multi-filament polyethylene yarn via a gel-spinning process, Wherein a spin finish is applied at least once in an amount of 0.1-10 mass % based on the filament, to a filament that contains less than 50 mass % of solvent; the spin finish comprising at least 95 mass % of at least one volatile compound having a boiling point at 0.1 MPa pressure of from 30 to 250° C.; and the spin finish is subsequently removed by exposing the filament to a temperature of below the melting temperature of the filament. With this process a yarn is made that has a very low amount of residues on the surface of the fibres, without the need for a washing or extraction step, showing good mechanical properties, and very suited for e.g. biomedical applications. The invention further relates to a process for converting polyolefin fibres into a semi-finished or end-use product.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: April 29, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Leo Smit, Joseph Arnold Paul Maria Simmelink, Leonard Josef Arnold Nielaba
  • Patent number: 7365195
    Abstract: The invention relates to a process for purifying caprolactam, said process comprising (a) subjecting the caprolactam to a hydrogenation by treating the caprolactam with hydrogen in the presence of a heterogeneous nickel containing hydrogenation catalyst, (b) distilling at least a portion of the hydrogenated caprolactam in a distillation column containing nickel in an amount sufficiently low such that ?PANNi?3, wherein ?PANNi=?PAN??PANNi=0, ?PAN=increase of the PAN number of caprolactam during distilling, ?PANNi=0 increase of the PAN number of caprolactam during distilling under the same conditions in a distillation column free of nickel. Nickel is removed from the caprolactam solution prior to the distillation step.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: April 29, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Joannes Albertus Wilhelmus J. A. W. Lemmens, Theodorus Maria T. M. Smeets, Paul Maria P. M. Brandts, Koen Harry Maria K. H. M. Ceyssens
  • Patent number: 7361775
    Abstract: The invention relates to a process for the preparation of (S)-glyceraldehyde acetonide in aqueous solution from 3,4-O-isopropylidene-L-threonic acid or a salt thereof in aqueous solution, and hypochlorite in aqueous solution wherein the aqueous hypochlorite solution has a pH>7.5 and wherein during addition of at least 0.1 molar equivalents of hypochlorite based on the amount of 3,4-O-isopropylidene-L-threonic acid, an acid solution is not simultaneously added. The invention also relates to a process according to the invention, wherein 3,4-O-isopropylidene-L-threonic acid or a salt thereof is prepared from 5,6-O-isopropylidene-L-ascorbic acid or a salt thereof in the presence of H2O2 and a base in a manner known per se, wherein excess H2O2 is optionally removed by catalase.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: April 22, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Peter Jan Leonard Mario Quaedflieg, Franciscus Alphons Marie Lommen, Robert Jan Vijn, Danniël Adrianus Franciscus Jacobus Boxtel Van
  • Patent number: 7361781
    Abstract: 2,3,5-Trimethyl-1,4-hydroquinone diacylates are obtained by reacting 3,5,5-trimethyl-1,4-benzoquinone with an acylating agent in the presence of methane trisulfonic acid as a catalyst.
    Type: Grant
    Filed: October 26, 2004
    Date of Patent: April 22, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Aquino Fabrice, Bonrath Werner, Pace Francesco
  • Patent number: 7361217
    Abstract: Method for crystallizing a melamine melt to form melamine particles with a D90 of at most 2 mm by cooling a melamine melt to below the crystallization temperature of the melamine, comprising the formation of a suspension of melamine particles in the cooling medium by spraying the melamine melt with at most 10 wt % of CO2 relative to the sprayed quantity of melamine melt in a space in which a layer of a liquid cooling medium is present that has a temperature below the crystallization temperature of the melamine and under cooling conditions at which at least 50 wt % of the sprayed melamine melt directly turns into suspended melamine particles. Method for the production of melamine from urea in a preferably continuous, high-pressure process, with application of the present method for the crystallization.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: April 22, 2008
    Assignee: DSM IP Assets B.V.
    Inventor: Tjay Tjien M. Tjioe
  • Publication number: 20080089852
    Abstract: The invention relates to the use of polymeric particles for boosting the UV absorption of an UV filter in an UV-sunscreen composition, wherein the polymeric particles comprise at least one polymeric particle comprising at least one chromophore having an UV absorption maximum at ?max?275 nm covalently bound thereto.
    Type: Application
    Filed: October 26, 2005
    Publication date: April 17, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jutta Hotz, Ulrich Huber, Volker Schehlmann, Daniel Sprenger
  • Patent number: 7358092
    Abstract: A method for quantitative determination of 25-hydroxycholecalciferol in feed is described. The method includes the steps of adding a defined amount of an internal standard which has a mass different from 25-hydroxycholecalciferol and a polarity similar to that compound, e.g., 26,27-hexadeutero-25-hydroxycholecalciferol, to an aqueous dispersion of the feed, extracting the aqueous dispersion with tert.butyl methyl ether and further processing the extract by HPLC and mass spectrometry as described in the specification.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: April 15, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Laurent Denu, Richard Goessl, Peter Hofmann
  • Patent number: 7358294
    Abstract: An aqueous coating composition comprising a crosslinkable water-dispersible polyurethane oligomer wherein said composition when drying to form a coating has an open time of at least 20 minutes, a wet-edge time of at least 10 minutes, a tack free time of <20 hours and an equilibrium viscosity of <5,000 Pa·s at a solids content when drying in the range of from 20 to 55 wt % using a shear rate in the range of from 9±0.5 to 90±5 s?1 and at 23+2° C.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: April 15, 2008
    Assignee: DSM IP Assets BV
    Inventors: Alfred Jean Paul Buckmann, Emilio Martin, Gerardus Cornelis Overbeek, Johannes Ludovicus Martinus Van Hilst, John Christopher Padget, Pablo Steenwinkel, Tom Annable, Ronald Tennebroek
  • Patent number: 7358357
    Abstract: The invention relates to a process for preparing caprolactam by admixture of cyclohexanone oxime to a reaction mixture comprising caprolactam and sulfuric acid using a mixing device, said mixing device comprising (i) a tube through which the reaction mixture can flow, and (ii) channels disposed around the tube, said channels opening into the tube, said process comprising: passing the reaction mixture through the tube, and feeding the cyclohexanone oxime into the reaction mixture through one or more of said channels, wherein Re>5000, Re being the Reynolds number as defined by ?·V·D/?, wherein ?=density (in kg/m3) of the reaction mixture that is fed to the tube V=velocity of the reaction mixture, V being defined as W/A, wherein W is the flow rate (in m3/s) of the reaction mixture that is fed into the tube and A is the cross section area of the tube (in m2) at the level where said channels open into the tube D=diameter of the tube at the level where said channels open into the tube (in m) ?=viscosity of th
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: April 15, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Theodorus Maria T. M. Smeets, Joannes Albertus Wihelmus J. A. W. Lemmens, Frank F. Mostert, Peter Wei-Hae P. W-H. Cheng
  • Patent number: 7358285
    Abstract: The present invention relates to a flame retardant polyamide compound comprising a polyamide polymer having a weight-average molecular weight of at least 10,000 g/mol, a polyamide oligomer having a weight-average molecular weight of at most 7500 and a halogen-free phosphorous containing flame retardant. The invention also relates to a process for preparing said flame retardant polyamide compound and to the use of said compound.
    Type: Grant
    Filed: December 10, 2003
    Date of Patent: April 15, 2008
    Assignee: DSM IP Assets B.V.
    Inventor: Johannes H. G. Ottenheijm
  • Patent number: 7354987
    Abstract: The invention relates to a compound of formula I: where: X is equal to NR5; R4 is equal to a C1-C12 alkyl group, aryl group, aralkyl group or cycloalkyl group. R1, R2, R3, R5 are equal to an H, alkyl, cycloalkyl, aryl of heterocyclic group; where R1, R2, and R5 or R1, R2, and R3 may together form a heterocyclic group. The invention also relates to a method for the preparation of this compound by reaction of an amino compound with an alkanol hemiacetal. The invention also relates to amino-aldehyde resins containing this compound and the application of these resins in adhesive compositions, laminates, shaped articles and transparent coatings.
    Type: Grant
    Filed: February 20, 2007
    Date of Patent: April 8, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Rudolfus Antonius Theodorus Maria Van Benthem, Renier Henricus Maria Kierkels, Jacobus Adriaan Antonius Vermeulen
  • Publication number: 20080081025
    Abstract: The invention provides a conjugate comprising a hyperbranched polymer covalently bonded to at least three UV absorbing chromophores having an UV absorption maximum ?max>270 nm. The conjugate is an effective and safe sunscreen which can advantageously be used in cosmetic compositions.
    Type: Application
    Filed: March 23, 2005
    Publication date: April 3, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Alexander Poschalko, Ulrich Huber, Volker Schehlmann
  • Patent number: 7351564
    Abstract: The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as animals, algae and microorganisms. It has a strong antioxidation property against reactive oxygen species. Astaxanthin is used as a coloring reagent, especially in the industry of farmed fish, such as salmon, because astaxanthin imparts distinctive orange-red coloration to the animals and contributes to consumer appeal in the marketplace.
    Type: Grant
    Filed: September 23, 2003
    Date of Patent: April 1, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Tatsuo Hoshino, Kazuyuki Ojima, Yutaka Setoguchi
  • Patent number: 7351820
    Abstract: The invention relates to a process for preparing caprolactam by Beckmann rearrangement of cyclohexanone oxime by feeding cyclohexanone oxime to a reaction mixture comprising (i) sulfuric acid (ii) SO3 and (iii) caprolactam , wherein the SO3 content of the reaction mixture is between 9 and 20 wt. % and the molar ratio M of the reaction mixture defined as (nso3+nH2SO4)/ncap is between 1 and 1.4, wherein nso3=quantity of SO3 in reaction mixture, in mol nso3=quantity of H2SO4 in reaction mixture, in mol ncap=quantity of caprolactam in reaction mixture, in mol.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: April 1, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Petrus Jozef Hubertus Thomissen, Joannes Albertus Wilhelmus Lemmens, Theodorus Maria Smeets
  • Publication number: 20080075933
    Abstract: The invention relates to a ballistic-resistant assembly comprising a stack of a plurality of flexible elements comprising at least one layer containing a network of high-strength fibres, wherein from 5 to 50 mass % of the elements in the rear side part of the assembly contain connecting means that interconnect adjacent elements at multiple spots distributed over their surface. The flexible assembly combines high bullet stopping power with a low trauma effect. The invention further relates to a ballistic-resistant article comprising said assembly and to a method of making said assembly.
    Type: Application
    Filed: July 1, 2005
    Publication date: March 27, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventor: Johannes Rovers
  • Patent number: 7344855
    Abstract: A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the respiratory chain is increased, transformed and novel nucleotide sequences.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: March 18, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Hans-Peter Hohmann, Nigel John Mouncey, Uwe Sauer, Nicola Zamboni
  • Publication number: 20080063674
    Abstract: The invention provides cosmetic compositions comprising a protein hydrolysate and a cosmetically acceptable excipient, wherein the protein hydrolysate has a high content of peptides with a terminal proline.
    Type: Application
    Filed: June 17, 2005
    Publication date: March 13, 2008
    Applicant: DSM IP ASSETS B.V.
    Inventors: Juergen Vollhardt, Philippe Maillan