Patents Assigned to DSM
  • MODIFIED TRANSKETOLASE AND USE THEREOF
    Publication number: 20130189731
    Abstract: The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic precursor like riboflavin (vitamin B2), FAD, FMN, pyridoxal phosphate (vitamin B6), guanosine, GMP, adenosine, AMP. The invention further pertains to the generation of the organism producing those compounds. It furthermore relates to the generation of mutated transketolases that allow normal growth on glucose but reduced growth on gluconate when introduced into the production strains and to polynucleotides encoding them.
    Type: Application
    Filed: July 26, 2012
    Publication date: July 25, 2013
    Applicant: DSM IP Assets B.V.
    Inventors: Michael Hans, Dietmar Laudert, Hans-Peter Hohmann, Martin Lehmann
  • PRODUCTION OF SECRETED PROTEINS BY FILAMENTOUS FUNGI
    Publication number: 20130189733
    Abstract: The present invention relates to a method to improve the secretion of a protein of interest by a filamentous fungal cell comprising inducing a phenotype in the cell selected from the group consisting of a lowered ERAD, an elevated UPR that does not induce an elevated ERAD, wherein ERAD preferably is lowered. The invention further relates to the filamentous fungal cell comprising the phenotype described above. The invention also relates to polynucleotides and polypeptides whose expression can be modulated in the filamentous fungal cell to obtain the above-described phenotype.
    Type: Application
    Filed: January 25, 2013
    Publication date: July 25, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: CORNELIS MARIA JACOBUS SAGT, CORNELIS THEODORUS VERRIPS, WALRAVEN HENRY MULLER, NOEL NICOLAAS MARIA ELISABETH VAN PEIJ
  • Process for extraction of glucosinolates from broccoli seeds
    Patent number: 8491944
    Abstract: A new process for extracting and purifying glucosinolates from plant material, preferably broccoli sprouts or seeds is described. An alcoholic extract is adsorbed onto a basic resin and eluted with ammonia. Optionally, the alcoholic extract is passed through an ion-exchange column containing acidic resin prior to the adsorption/elution step.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: July 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Christof Wehrli, Jan Schutz
  • Colour stable thermoplastic composition
    Patent number: 8492462
    Abstract: The present invention relates to a color stable thermoplastic composition comprising a copolyester elastomer; and a stabilizer comprising (i) an aromatic amine; and (ii) a di-substituted imidazoline, wherein the color lightness (L*) of the composition is greater than 50. The invention also relates to the molded articles produced from the color stable thermoplastic compositions and the use thereof in automotive applications.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: July 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventor: Franciscus J. M. Souren
  • Solvent borne polyurethane composition
    Patent number: 8492458
    Abstract: A solvent borne polyurethane composition with a polymodal molecular weight distribution comprising: i) 10 to 90 wt % of at least a polyurethane A with a Mw in the range of from 4,000 up to 25,000 g/mol, ii) 90 to 10 wt % of at least a polyurethane B with a Mw in the range of from 25,000 to 100,000 g/mol and iii) a liquid medium.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: July 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Ester Parra Pastor, Joan Tiana Ruiz, Urs Jürgen Frieden Hugel
  • Method for improving the color index of organopolysiloxanes
    Patent number: 8492575
    Abstract: The present invention relates to method for improving the color index of an organopolysiloxanes functionalized with a benzalmalonate said method comprising the step of contacting said organopolysiloxanes functionalized with a benzalmalonate with a hydroxy carboxylic acid or a cyclic ester thereof in an organic solvent.
    Type: Grant
    Filed: November 27, 2009
    Date of Patent: July 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Friedhelm Nickel, Peter Will
  • METHOD FOR ISOLATING A CYCLOHEXAPEPTIDE
    Publication number: 20130184433
    Abstract: The present invention relates to a method for isolating acyclohexapeptide and to a novel crystalline form of caspofungin diacetate thus obtained.
    Type: Application
    Filed: September 26, 2011
    Publication date: July 18, 2013
    Applicant: DSM Sinochem Pharmaceuticals
    Inventors: Robertus Mattheus De Pater, Dhiredj Chandre Jagesar
  • RADIATION CURABLE AQUEOUS COMPOSITION FOR LOW GLOSS COATINGS
    Publication number: 20130184396
    Abstract: A radiation curable aqueous coating composition having a 85° gloss of ?60 upon drying comprising (A) 10 to 99 wt % of a polyurethane, (B) 1 to 90 wt % of a radiation curable component; (C) 0.1 to 10 wt % of an associative thickener; wherein at least 80 wt % of (A)+(B)+(C) has a particle size greater than 500 nm and wherein the C?C bond concentration of the composition is 0.2 to 5.0 mmol per g of (A)+(B)+(C).
    Type: Application
    Filed: March 7, 2013
    Publication date: July 18, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Ilse VAN CASTEREN, Roland TENNEBROEK, Mario Cornelis SCHOONDERMARK, Paul DE KOK
  • Unsaturated polyester
    Patent number: 8487041
    Abstract: The present invention relates to a resin composition comprising (a) an unsaturated polyester resin having a molecular weight Mn of at least 750 Dalton and at most 5000 Dalton and (b) a reactive diluent, wherein the unsaturated polyester resin comprises C5-C10 unsaturated diacid building blocks and isosorbide building blocks. Preferably, at least part of the isosorbide is derived from a non-fossil source. Preferably, itaconic acid or anhydride is used as the C5 unsaturated dicarboxylic acid.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: July 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Stefanus Jacobus Duyvestijn
  • ESTERS OF HEXANOIC ACIDS AS INTERMEDIATES FOR THE PREPARATION OF ATORVASTATIN
    Publication number: 20130178636
    Abstract: The invention relates to compounds of general formula (3) wherein R4 is allyl, 2-butyl, cyclohexyl, 3-methyl-2-butyl or 4-methyl-2-pentyl, a method for the preparation of compounds of general formula (3) and their use in the preparation of atorvastatin.
    Type: Application
    Filed: September 12, 2011
    Publication date: July 11, 2013
    Applicant: DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V.
    Inventors: Ben De Lange, Henricus Leonardus Marie Elsenberg, Henricus Wilhelmus Leonardus Marie Vaessen
  • VITAMIN POWDER COMPOSITION AND METHOD OF MAKING
    Publication number: 20130177619
    Abstract: A powder composition containing at least one fat-soluble vitamin dispersed in a matrix of a natural polysaccharide gum or a mixture of gums having an emulsifying capacity and/or a protein or a mixture of proteins having an emulsifying capacity. The fat-soluble vitamin in the powder compositions is in the form of droplets having an average diameter in the range of about 70 to about 200 nm. Tablets, beverages and beverage concentrates, foods, cosmetics and pharmaceuticals containing the powder composition can be made.
    Type: Application
    Filed: March 4, 2013
    Publication date: July 11, 2013
    Applicant: DSM NUTRITIONAL PRODUCTS, INC.
    Inventors: CHYI-CHENG CHEN, BRUNO LEUENBERGER
  • Extraction and winterization of lipids from oilseed and microbial sources
    Patent number: 8480904
    Abstract: A process for purifying a lipid composition having predominantly neutral lipid components having at least one long chain polyunsaturated fatty acid is disclosed. The process employs contacting the lipid composition with a polar solvent, such as acetone, wherein the solvent is selected such that contaminants are less soluble in the solvent than is the long chain polyunsaturated fatty acid. The process is typically conducted at cooler temperatures, including about 0° C. Upon precipitation of the contaminants from the lipid composition, a separation is conducted to remove the precipitated material from the lipid composition. The long chain polyunsaturated fatty acids can include ARA, DPA, EPA, and/or DHA. The process of the present invention effectively winterizes lipid compositions, thereby reducing the tendency of such compositions to become hazy.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: July 9, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Daniel G. Dueppen, Samuel G. Zeller, Sandra I. Diltz, Robert H. Driver
  • Method for improving the color index of organopolysiloxanes
    Patent number: 8481775
    Abstract: The present invention relates to method for improving the color index of organopolysiloxanes functionalized with at least one UV-light absorbing group said method comprising the step of contacting said group carrying organopolysiloxanes with a hydroxy carboxylic acid or a cyclic ester thereof in an organic solvent.
    Type: Grant
    Filed: November 27, 2009
    Date of Patent: July 9, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Friedhelm Nickel, Peter Will
  • DICARBOXYLIC ACID PRODUCTION PROCESS
    Publication number: 20130171704
    Abstract: Process for producing a dicarboxylic acid comprising fermenting a microorganism in a suitable fermentation medium wherein a gas flow comprising 30% to 100% v/v oxygen as measured under atmospheric pressure is added to the fermentation medium and producing the dicarboxylic acid.
    Type: Application
    Filed: September 20, 2011
    Publication date: July 4, 2013
    Applicants: ROQUETTE FRERES SA, DSM IP ASSETS B.V.
    Inventors: Mickel Leonardus August Jansen, Laurent Segueilha, Rene Verwaal, Melanie Louchart
  • Methods for Improving Cognitive Function and Decreasing Heart Rate
    Publication number: 20130172412
    Abstract: The present invention is directed to methods of improving cognitive function in subjects having age related cognitive decline or mild cognitive impairment and to methods of decreasing heart rate in a subject by administering dosage forms comprising docosahexaenoic acid (DHA) substantially free of eicosapentaenoic acid (EPA).
    Type: Application
    Filed: December 13, 2012
    Publication date: July 4, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Laminate and composite layer comprising a substrate and a coating, and a process and apparatus for preparation thereof
    Patent number: 8475897
    Abstract: The invention relates to a laminate comprising two plastic films and in between a metal or metaloxide layer and a crystalline triazine layer, the laminate having a lamination strength of about 2 N/inch or more as measured in a 90 degree tensile testing at 30 mm/min. The invention further relates to a composite layer, comprising a metal or metal oxide, and a triazine layer comprising a triazine compound suitable for said laminate. The invention further relates to a process for the preparation of a composite layer, comprising the step of applying a triazine layer on a substrate with a metal or metal oxide layer by vapor deposition of the triazine compound, wherein the process comprises (a) applying to the metal or metal oxide layer a compound other than a triazine compound, (b) vapor depositing the triazine compound on the metal or metal oxide layer while the compound is at least in part in a liquid state.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: July 2, 2013
    Assignees: DSM IP Assets B.V., Biofilm S.A., Applied Materials GmbH & Co. KG
    Inventors: Shahab Jahromi, Gerardus Johannes Paulus Krosshof, Alexandra Lorena Quiceno Gomez, Gerd Hoffmann
  • Chain comprising links
    Patent number: 8468793
    Abstract: The present invention relates to a chain comprising a plurality of first links (100) interconnected with a plurality of adjacent links, the first links comprising polymeric multifilament yarns (110) and having a thickness (Formula (I)), at least at the portion where they interconnect with the adjacent links wherein said adjacent links have a thickness (Formula (II)) at least at the portion where they interconnect with the first links and wherein the ratio (Formula (II)/Formula (I)) is at least 1.2. The invention further relates to the use of the chain for storing, securing, and handling cargo, e.g. in lifting, hauling and rigging.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: June 25, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Dietrich D. Wienke, Roelof R. Marissen, Martinus Johannes Nicolaas M. J. N. Jacobs, Christiaan Henri Peter Dirks
  • Unsaturated polyester resin
    Patent number: 8470926
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate ester units as reactive unsaturation, wherein the resin comprises itaconate, citraconate and mesaconate ester units. Preferably, the resin comprises itaconate, citraconate and mesaconate ester units in an amount of from 40 to 90 mol % itaconate, from 2 to 30 mol % citraconate and from 5 to 40 mol % mesaconate in which 100 mol % is the total amount of itaconate, citraconate and mesaconate esters units.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: June 25, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Stefanus Jacobus Duyvestijn, Silvana Rensina Antonnietta Di Silvestre
  • PROCESS TO PRODUCE ALKENOIC ACID ESTERS FROM LACTONES
    Publication number: 20130158286
    Abstract: This invention relates to a process for the preparation of alkenoic acid esters comprising contacting a lactone with an alcohol and an acidic heterogeneous catalyst, characterised in that the process is carried out in the presence of at least 20 ppm of an acid having a pKa of 5 or less, relative to the amount of the lactone. The presence of at least 20 ppm of an acid having a pKa of 5 or less may stabilise the catalyst during the reaction and may also be used for reactivating an acidic heterogeneous catalyst. The improved yield advantageously allows energy conservation.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 20, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Production of High Levels of DHA in Microalgae Using Modified Amounts of Chloride and Potassium
    Publication number: 20130158280
    Abstract: Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.
    Type: Application
    Filed: February 7, 2013
    Publication date: June 20, 2013
    Applicant: DSM IP Assets B.V.
    Inventor: DSM IP Assets B.V.