Patents Assigned to DSM
  • Publication number: 20130125738
    Abstract: The invention concerns an improved yarn package and a method winding a package of high Young's modulus yarn. The package has a low normalized standard deviation in unwinding tension and hence is very suitable for converting into a range of yarn constructions and particularly medical products.
    Type: Application
    Filed: April 7, 2011
    Publication date: May 23, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Evert Florentinus Florimondus De Danschutter, Herbert Rabe, Carsten Goerke
  • Publication number: 20130123427
    Abstract: The invention relates to a process for the preparation of polymers and to an apparatus for performing this process. The apparatus comprises devices and reactors that are combined in the sequence of first a mixing device, second a flow microwave and optionally third one or more additional reactors.
    Type: Application
    Filed: April 1, 2011
    Publication date: May 16, 2013
    Applicants: DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG, DSM IP ASSETS B.V.
    Inventor: Karsten Luettgen
  • Patent number: 8440458
    Abstract: The invention relates to a process for the culturing of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: May 14, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Gerben Meile Zijlstra, Robert Patrick Hoff, Jacob Schilder
  • Publication number: 20130115182
    Abstract: The present invention relates to the use of steviol and/or isosteviol, or a salt, ester, a diester, or an ether thereof as depicted in formula (I), formula (I): R1 wherein R1 is hydrogen (H) or a saturated, straight or branched C1-C8 alkyl group non substituted or substituted with up to 3 hydroxyl-, alkoxy-, amino-, alkylamino- or dialkylamino-groups, R2 is independently a saturated, straight or branched C1-C8 alkyl group, —O—C1-C8 alkyl group, —OH group, a —O—C(O)—C1-C8 alkyl, or, —COO(C1-C8 alkyl) group, R3 is independently CH2, O, or CH—(C1-C7 alkyl), wherein the enhancement of the appearance of hair is selected from the group consisting of: restoring hair color and delaying the onset of greyness in hair, lessening hair loss, restoring hair growth after the onset of baldness has occurred, increasing the thickness of hair, counteracting age-associated hair thinning, preventing premature hair loss, or delaying the onset or severity of age-associated hair loss and thinning, maintaining of the natural hair col
    Type: Application
    Filed: July 20, 2011
    Publication date: May 9, 2013
    Applicant: DSM NUTRITIONAL PRODUCTS LTD.
    Inventors: Regina Goralczyk, Remo Graeub, Annis Olivia Mayne-Mechan, Hasan Mohajeri, Jenny Piussi, Henry Rieger
  • Publication number: 20130109822
    Abstract: The present invention relates to the polymeric reaction product of compounds according to Formula (I) and Formulae (II) or (III). Formula (I) has the following structure: where R1, R2, R3 and R4 are independently H, OH, optionally substituted C1-12alkyl, optionally substituted C1-12alkenyl, C1-12aldehyde, C3-12acetals, C2-12 ether, and/or C2-12 ester; where optionally at least one of R1, R2, R3 and R4 is H. Formulae (II) and (III) have the following structure: where X is H or C1-4alkyl; Y is OH or OR5 where R5 is C1-12alkyl, C3-12aryl, C4-12aralkyl or C3-12cycloalkyl; and Z is an electron-withdrawing group.
    Type: Application
    Filed: December 19, 2012
    Publication date: May 2, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Rudolfus Antonius Theodorus Maria VAN BENTHEM, Stijn WITTERS
  • Patent number: 8431727
    Abstract: The present invention relates to novel processes for the manufacture of chroman derivatives such as ?-tocopherol (TCP) and alkanoates thereof, especially ?-tocopheryl acetate (TCPA), whereby at least one step of the processes is carried out in the presence of a Lewis acid or a mixture of a Lewis acid with a Bronsted acid as the catalyst under pressure, preferably at an absolute pressure of at least 1.1 bar. As starting materials for the manufacture of TCP and its alkanoates either a mixture of 2,3,5-trimethylhydroquinone (TMHQ) or 2,3,6-trimethylhydroquinone-1-alkanoate (TMHQA) and a compound selected from the group consisting of phytol (PH), isophytol (IP) and (iso)phytol derivatives or 2-phytyl-3,5,6-trimethyl-hydroquinone (PTMHQ)/3-phytyl-2,5,6-trimethylhydroquinone-1-alkanoate (PTMHQA) and/or an isomer thereof are used. Suitable Lewis acids are indium(III) salts and scandium(III) salts. Suitable acid mixtures are iron/iron(II) chloride/hydrogen chloride and zinc(II) chloride/hydrogen chloride.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: April 30, 2013
    Assignee: DSM Assets B.V.
    Inventors: Werner Bonrath, Yann Foricher, Thomas Netscher, Angela Wildermann
  • Publication number: 20130101837
    Abstract: Radiation-curable coating compositions for a surface such as a concrete floor, which include at least one multi-functional monomer or oligomer, a polymer, at least one photoinitiator, and one or more tertiary amine compounds containing zero or one crosslinkable double bonds are described and claimed. These coating compositions allow for application of at least about 0.15 mm (6 mil) thickness of the coating composition over an area larger than a UV radiation source, without the formation of wrinkles or buckles following each pass of the UV radiation source in the areas where light leakage from a side light shielding of the UV radiation source results in a very weak radiation intensity.
    Type: Application
    Filed: June 30, 2011
    Publication date: April 25, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Huimin Cao, Wenguang Li, Tai Yeon Lee
  • Publication number: 20130101861
    Abstract: Radiation-curable coating compositions for a surface such as a concrete floor, which include at least one multi-functional monomer or oligomer, at least one photoinitiator, at least one glossy band matting agent, and at least one matte band matting agent are described and claimed. These low gloss coating compositions allow for application of the coating composition over an area larger than a UV radiation source, while minimizing the formation of gloss bands or gloss lines that exhibit a different level of gloss in the areas where light leakage from a side light shielding of the UV radiation source results in a very weak radiation intensity, as compared to the areas subjected to high radiation intensity. These low gloss coating compositions are optionally clear topcoat compositions.
    Type: Application
    Filed: June 30, 2011
    Publication date: April 25, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Huimin Cao, Wenguang Li, Tai Yeon Lee
  • Publication number: 20130104264
    Abstract: The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 25, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Margot Elisabeth Francoise Schoonneveld-Bergmans, Wilbert Herman Marie Heijne, Rene Marcel De Jong, Robbertus Antonius Damveld
  • Patent number: 8426182
    Abstract: This invention relates to an alpha-amylase, a process for its preparation and the use of the amylase. The invention relates to a newly identified polynucleotide sequence from Alicyclobacillus pohliae comprising a gene that encodes the alpha-amylase enzyme. The invention features the full-length coding sequence of the gene as well as the amino acid sequence of the full-length functional protein of the gene. The invention also relates to methods of using these proteins in industrial processes, for example in food industry, such as the baking industry. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins and cells.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventor: Lucie Parenicova
  • Patent number: 8426020
    Abstract: The invention provides an optical fiber coated with a Supercoating, wherein the Supercoating comprises at least two layers, wherein the first layer is a Primary Coating that is in contact with the outer surface of the optical fiber and the second layer is a Secondary Coating in contact with the outer surface of the Primary Coating, wherein the cured Primary Coating on the optical fiber has the following properties after initial cure and after one month aging at 85° C. and 85% relative humidity: A) a % RAU of from about 84% to about 99%; B) an in-situ modulus of between about 0.15 MPa and about 0.60 MPa; and C) a Tube Tg, of from about ?25° C. to about ?55° C.; wherein the cured Secondary Coating on the optical fiber has the following properties after initial cure and after one month aging at 85° C. and 85% relative humidity: A) a % RAU of from about 80% to about 98%; B) an in-situ modulus of between about 0.60 GPa and about 1.90 GPa; and C) a Tube Tg, of from about 50° C. to about 80° C.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Steven R. Schmid, Petrus Jacobus Hubertus Niels, Paulus Antonius Maria Steeman, Xiaosong Wu, Wendell Wayne Cattron, Tyson Dean Norlin, Edward J. Murphy, John M. Zimmerman, Anthony Joseph Tortorello
  • Patent number: 8426686
    Abstract: Disclosed are novel acyl-CoA synthetases and novel acyltransferases, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified organisms (microorganisms and plants) comprising the same, and methods of making and using the same. Also disclosed are genetically modified organisms (e.g., plants, microorganisms) that have been genetically modified to express a PKS-like system for the production of PUFAs (a PUFA PKS system or PUFA synthase), wherein the organisms have been modified to express an acyl-CoA synthetase, to express an acyl transferase, to delete or inactivate a fatty acid synthase (FAS) expressed by the organism, to reduce competition for malonyl CoA with the PUFA synthase or to increase the level of malonyl CoA in the organism, and in one aspect, to inhibit KASII or KASIII.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: James G. Metz, Jerry M. Kuner, James Casey Lippmeier
  • Patent number: 8425930
    Abstract: The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: April 23, 2013
    Assignees: The Regents of the University of California, DSM Food Specialties USA Inc.
    Inventors: Mariana Barboza, J. Bruce German, Carlito Lebrilla, David Mills, Samara Freeman, William Robert King
  • Patent number: 8426617
    Abstract: The invention relates to the (stereoselective) hydrogenation of carbon-carbon double bonds in compounds having at least one such bond, e.g., isoprenoids, non-cyclic sesquiterpenes, tocomonoenols, tocodienols, tocotrienols or derivatives thereof, as well as to the (stereoselective) hydrogenation of parts/extracts of plant oils containing such tocotrienols or derivatives thereof, in the presence of a chiral Ir complex as the catalyst, whereby preferably one stereoisomer is manufactured in an excess.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Werner Bonrath, Frederik Menges, Thomas Netscher, Andreas Pfaltz, Bettina Wustenberg
  • Patent number: 8426619
    Abstract: A process for continuously producing furfural and levulinic acid from biomass, said process comprising steps including pre-treatment of the biomass; hydrolysis and dehydration of the biomass; removing a vapor mixture by flashing the slurried biomass and a heat integration step comprising the water used being heated through a heat exchange system with the flashed vapor mixture.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Rudy Francois Maria Jozef Parton, Marinus Petrus Wihelmus Maria Rijkers, Johannes Augustinus Kroon
  • Patent number: 8426021
    Abstract: The invention relates to a Radiation Curable Secondary Coating composition for use on an Optical Fiber. The Radiation Curable Secondary Coating composition is a urethane-free Alpha Oligomer prepared by reaction of the following: (a) an acrylate compound selected from an alcohol-containing acrylate or alcohol-containing methacrylate compound, (b) an anhydride compound, (c) an epoxy-containing compound, (d) optionally an extender compound, and (e) optionally a catalyst. The invention also relates to a coated wire and to a coated optical fiber.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: April 23, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Wendell Wayne Cattron, Steven R. Schmid, Edward J. Murphy, John M. Zimmerman, Anthony Joseph Tortorello
  • Publication number: 20130095532
    Abstract: The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 82% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 82% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 18, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Margot Elisabeth Francoise Schoonneveld-Bergmans, Wilbert Herman Marie Heijne, Alrik Pieter Los
  • Publication number: 20130095553
    Abstract: The invention relates to a polypeptide which comprises the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 76% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 76% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 18, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Margot Elisabeth Francoise Schooneveld-Bergmans, Wilbert Herman Marie Heijne, Alrik Pieter Los
  • Publication number: 20130095531
    Abstract: The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 70% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 70% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 18, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Margot Elisabeth Francoise Schooneveld-Bergmans, Wilbert Herman Marie Heijne, Rene Marcel De Jong, Robbertus Antonius Damveld
  • Publication number: 20130095527
    Abstract: The invention relates to a process for the coloring of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture.
    Type: Application
    Filed: December 6, 2012
    Publication date: April 18, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP Assets B.V.