Patents Assigned to DSM
  • Patent number: 8420835
    Abstract: Novel catalytic processes for the production of carnosol from carnosic acid are presented. The carnosic acid may be in pure form, in an impure form, part of a plant extract, or may be present in rosemary needles. The catalyst may be iron, iron salts, a minor amount of water, rosemary needles, or a mixture thereof.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventor: Christof Wehrli
  • Patent number: 8420778
    Abstract: The invention relates to compounds and to the cosmetically acceptable salts thereof, which correspond to general formula (I), wherein: R1 represents H, —C(O)—R6, —SO2—R6 or —C(O)—XR6; R2 and R4, independent of one another, represent (CH2)n—NH2 or (CH2)3—NHC(NH)NH2; n equals 1 4; R3 represents linear or branched C1-C4 alkyl that is optionally substituted by hydroxy; R5 and R6, independent of one another, represent hydrogen, optionally substituted (C1-C24)alkyl, optionally substituted C2-C24 alkenyl, optionally substituted phenyl, optionally substituted phenyl-C1-C4 alkyl or 9-fluorenyl-methyl; X represents oxygen (—O—) or NH—; or XR5 with X?O also represents the esters of a-tocopherol, tocotrienol or retinol, with the provision that R1 and R5 do not represent hydrogen and X does not represent oxygen at the same time. The invention also relates to the production of the compounds of general formula (I) and to a cosmetically active composition that contains at least one compound of formula (I).
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Hugo Ziegler, Marc Heidl, Dominik Imfeld
  • Patent number: 8420838
    Abstract: According to the invention, a process for the rectification of mixtures of high-boiling air- and/or temperature-sensitive substances which require a high separation efficiency is proposed, in particular a process for the working-up of a VE- or VEA-containing product stream. The process is characterized in particular in that, in a first purification stage, low-boiling products and unspecified isomers of the useful product are separated from the product stream virtually without loss of useful product and that, in a second purification stage, the useful product is removed in a stream having a purity of >97% by weight and a further stream having a purity of >92% by weight. A preferred embodiment of the process serves for working up VEA, in which the loss of useful product in the first purification stage is less than 5%, based on that amount of VEA in the feed which is added to the purification stage per unit time.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Juan Herguijuela, Werner Pietzonka, Angela Wildermann, Thomas Wolf
  • Patent number: 8420677
    Abstract: Use of DIM and/or its derivatives for prevention, treatment and/or delay of age-related hearing loss in mammals.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Hubert Hug, Bernd Mussler, Daniel Raederstorff, Ying Wang-Schmidt
  • Patent number: 8420806
    Abstract: The present invention relates to a process for the preparation of cefadroxil in crystal form, comprising a) adding an aqueous solution of cefadroxil to a crystallization vessel and a titrant to keep a pH in the crystallization vessel of between 7 to 9; and b) lowering the pH in the crystallization vessel to a value of between 5 and 6.5 to obtain a suspension of the ?-lactam compound in crystal form. The invention further relates to cefadroxil in crystal form obtainable by the process according to the present invention. The invention also relates to cefadroxil in crystal form with a CIE b value of below 12 when stored at a temperature of 25° C. for at least 1 month.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: April 16, 2013
    Assignee: DSM Sinochem Pharmaceuticals Netherlands B.V.
    Inventors: Carlos Enrique Lenhard, Harold Monro Moody, Theodorus Johannes Godfried Maria Van Dooren
  • Patent number: 8420609
    Abstract: The present invention describes natamycin comprising needle shaped crystals.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: April 16, 2013
    Assignee: DSM IP Assets, B.V.
    Inventors: Ben Rudolf de Haan, Ferdinand Theodorus Jozef van Rijn
  • Patent number: 8420683
    Abstract: The present invention relates to 5-substituted hydantoins, a process for the preparation of 5-substituted hydantoins and the use of 5-substituted hydantoins in the preparation of enantiomerically enriched ?-amino acids. Furthermore, the present invention relates to the preparation of pharmaceutically active products such as perindopril and ramipril using the novel 5-substituted hydantoins.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: April 16, 2013
    Assignee: DSM Sinochem Pharmaceuticals Netherlands B.V.
    Inventors: Georgios Sarakinos, Wilhelmus Hubertus Joseph Boesten, Dennis Heemskerk, Ben De Lange
  • Patent number: 8414850
    Abstract: A rectification column and system for the working-up of a vitamin E (VE)- and/or vitamin E acetate (VEA)-containing product stream includes purification of a vitamin E-containing product stream, acetylation of at least a part of the purified vitamin E and purification of at least a part of the acetylated vitamin E, the purification of vitamin E and vitamin E acetate preferably being effected by distillation, for example rectification.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: April 9, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Werner Pietzonka, Peter Ruckstuhl, Angela Wildermann
  • Publication number: 20130084461
    Abstract: The invention provides a process for preparing organic nanoparticles comprising the steps of: (a) preparing a solution comprising an unsaturated polyester and/or a vinyl ester resin, an initiator and a hydrophobic monomer; (b) emulsifying the solution obtained in step (a) in an aqueous phase; and thereafter (c) curing the emulsified solution. The invention further provides organic nanoparticles obtainable by the process according to the invention; various uses of said nanoparticles; and paper, dye compositions and toner compositions comprising said nanoparticles.
    Type: Application
    Filed: November 29, 2012
    Publication date: April 4, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Patent number: 8408219
    Abstract: Dental floss products are provided which include a unitary tape of ultra-high molar mass polyethylene having an intrinsic viscosity of at least 5 dl/g, as measured in decalin at 135° C., the tape having a thickness of about 0.02-0.1 mm and a width of about 0.25-6 mm, and a tensile strength of at least 1.8 GPa. The dental floss products have very high mechanical, especially tensile strength, and show high resistance to tearing and has a low coefficient of friction. The tape can be inserted between teeth tightly together without breaking. A further advantage of the dental tape products is that most of the initial strength during flossing is retained, even if the tape separates into filaments. Processes for making a unitary tape suitable for use in a dental floss product are also provided.
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: April 2, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Carina S. Snijder, Christiaan H. P. Dirks, Leonard J. A. Nielaba
  • Patent number: 8409617
    Abstract: A powder composition containing at least one fat-soluble vitamin dispersed in a matrix of a natural polysaccharide gum or a mixture of gums having an emulsifying capacity and/or a protein or a mixture of proteins having an emulsifying capacity. The fat-soluble vitamin in the powder compositions is in the form of droplets having an average diameter in the range of about 70 to about 200 nm. Tablets, beverages and beverage concentrates, foods, cosmetics and pharmaceuticals containing the powder composition can be made.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: April 2, 2013
    Assignee: DSM Nutritional Products Inc.
    Inventors: Chyi-Cheng Chen, Bruno Leuenberger
  • Publication number: 20130079548
    Abstract: This invention relates to a process for the preparation of alkenoic acid esters comprising contacting a lactone with an alcohol and an acidic catalyst in the gas phase, characterised in that the process is carried out in the presence of at least 0.26 wt. % water, relative to the amount of the lactone. The process may result in a good production yield and selectivity with respect to the production of alkenoic acid esters and may also result in less formation of dialkylethers. The improved yield advantageously allows energy conservation.
    Type: Application
    Filed: September 21, 2012
    Publication date: March 28, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: DSM IP ASSETS B.V.
  • Patent number: 8404148
    Abstract: The present invention relates to a polymer composition with an increased rate of oxygen-uptake by the presence of an oxidation catalyst. The invention further relates to a process to increase the rate of oxygen-uptake by a polymer composition. The invention also relates to a process to increase the oxo-biodegradability of a polymer composition and to the use of such a composition for the preparation of a product having a controlled lifetime. The invention further relates to a process to increase the rate of oxygen-scavenging in a composition containing a carbon-containing polymer, the composition obtained by this method and its use in the preparation of an oxygen-scavenging product. The present invention further relates to objects containing an oxygen scavenging layer containing such a composition.
    Type: Grant
    Filed: July 4, 2007
    Date of Patent: March 26, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Pieter Gijsman, Johan Franz Gradus Antonius Jansen, Dirk Armand Wim Stanssens
  • Publication number: 20130071887
    Abstract: This invention is directed to a process for cleaving glycoside residues from stevioside to produce steviol using a commercially available enzyme mixture containing pectinase, CYTOLASE PCL5®. In preferred methods, the reaction takes place in the presence of a yeast culture. Also described are combinations of Helix pomatia enzymes and CYTOLASE PCL5®.
    Type: Application
    Filed: January 6, 2011
    Publication date: March 21, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventor: Christof Wehrli
  • Patent number: 8399215
    Abstract: The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least about 70% sequence identity to the amino acid sequence set out in SEQ ID NO: 3 and wherein the nucleotide sequence is heterologous to the host. The cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: March 19, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Paul Klaassen, Jan Metske Van Der Laan, Bianca Elisabeth Maria Gielesen, Gijsberdina Pieternella Van Suylekom
  • Patent number: 8399768
    Abstract: The invention relates to an insulated wire for use in electronic equipment, comprising an electrically conductive core and an insulating layer and/or an insulating jacket consisting of a flame retardant elastomeric composition surrounding the electrically conductive core, wherein the flame retardant elastomeric composition comprises a elastomeric polymer selected from the group consisting of styrenic block copolymers, olefinic thermoplastic elastomers and combinations thereof; and a metal salt of a phosphinic acid of the formula [R1R2P(O)O]?mMm+ (formula I) and/or a diphosphinic acid of the formula [O(O)PR1—R3—PR2(O)O]2?nMxm+ (formula II), and/or a polymer thereof, wherein R1 and R2 are equal or different substituents chosen from the group consisting of hydrogen, linear, branched and cyclic C1-C6 aliphatic groups, and aromatic groups, R3 is chosen from the group consisting of linear, branched and cyclic C1-C10 aliphatic groups and C6-C10 aromatic and aliphatic-aromatic groups, M is a metal chosen from the gro
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: March 19, 2013
    Assignee: DSM IP Assets B.V.
    Inventor: Angelika Schmidt
  • Patent number: D678200
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: March 19, 2013
    Assignee: DSM&T Company, Inc.
    Inventor: Sergio Corona
  • Patent number: D678201
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: March 19, 2013
    Assignee: DSM&T Company, Inc.
    Inventor: Sergio Corona
  • Patent number: D678203
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: March 19, 2013
    Assignee: DSM&T Company, Inc.
    Inventor: Sergio Corona
  • Patent number: D678204
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: March 19, 2013
    Assignee: DSM&T Company, Inc.
    Inventor: Sergio Corona