Patents Assigned to E
  • Patent number: 4734424
    Abstract: Bicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CH.dbd.CH-- or --CH.sub.2 --CH.sub.2 --; n is 1 to 5; Q is --CH.dbd.CH--, --CH.sub.2 --, ##STR2## or a single bond; R is CO.sub.2 H, CO.sub.2 alkyl, CO.sub.2 alkali metal, CO.sub.2 polyhydroxyamine salt, --CH.sub.2 OH, ##STR3## wherein R.sup.4 and R.sup.5 are the same or different and are H, lower alkyl, hydroxy, lower alkoxy or aryl, at least one of R.sup.4 and R.sup.5 being other than hydroxy and lower alkoxy; p is 1 to 4; R.sup.1 is H or lower alkyl; q is 1 to 12; R.sup.2 is H or lower alkyl; and R.sup.3 is H, lower alkyl, lower alkenyl, lower alkynyl, aryl, arylalkyl, lower alkoxy, aryloxy, arylalkyloxy, amino, alkylamino arylamino, arylalkylamino, lower alkyl-S-, aryl-S-, arylalkyl-S-, ##STR4## (wherein n' is 0, 1 or 2), alkylaminoalkyl, arylaminoalkyl, arylalkylaminoalkyl, alkoxyalkyl, aryloxyalkyl or arylalkoxyalkyl.
    Type: Grant
    Filed: September 24, 1986
    Date of Patent: March 29, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Steven E. Hall, Joyce Reid
  • Patent number: 4734352
    Abstract: Electrostatic liquid developer having improved charging characteristics consisting essentially of(A) nonpolar liquid having a Kauri-butanol value of less than 30, present in a major amount,(B) thermoplastic resin particles having an average by area particle size of less than 10 .mu.m.(C) nonpolar liquid soluble ionic or zwitterionic compound, and(D) a polyhydroxy compound, preferably soluble in the developer in an amount of at least 2% by weight.The electrostatic liquid developers are useful in copying making proofs including digital color proofs, lithographic printing plates, and resists.
    Type: Grant
    Filed: April 22, 1986
    Date of Patent: March 29, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Robert D. Mitchell
  • Patent number: 4734426
    Abstract: 5,6-Epoxy-7-oxabicycloheptane substituted diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CH.dbd.CH-- or --CH.sub.2 --CH.sub.2 --; n is 1 to 5; R is CO.sub.2 H, CO.sub.2 alkyl, CO.sub.2 alkali metal, CO.sub.2 polyhydroxyamine salt or ##STR2## q is 1 to 12; and R.sup.1 is H, lower alkyl, lower alkenyl, lower alkynyl, aryl, arylalkyl, lower alkoxy, aryloxy, arylalkyloxy, amino, alkylamino arylamino, arylalkylamino, ##STR3## (wherein n' is 0, 1 or 2), alkylaminoalkyl, arylaminoalkyl, arylalkylaminoalkyl, alkoxyalkyl, aryloxyalkyl or arylalkoxyalkyl.The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.
    Type: Grant
    Filed: September 24, 1986
    Date of Patent: March 29, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Jagabandhu Das
  • Patent number: 4734496
    Abstract: .beta.-Lactams having a sulfonic acid salt substituent in the 1-position, an acylamino substituent in the 3-position and an --NR.sub.2 R.sub.3 substituent in the 4-position wherein R.sub.2 and R.sub.3 are the same or different and each is ##STR1## or R.sub.2 and R.sub.3 together with the nitrogen atom to which they are attached are ##STR2## R.sub.4 is alkyl, aryl or arylalkyl; and R.sub.5 and R.sub.6 are the same or different and each is hydrogen, halogen, alkyl, alkoxy, alkylthio, alkoxycarbonyl, carboxyl or a carboxyl salt; have antibacterial activity.
    Type: Grant
    Filed: May 29, 1981
    Date of Patent: March 29, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Uwe D. Treuner, Theodor Denzel, Hermann Breuer
  • Patent number: 4734463
    Abstract: A hydroxy functional urethane modified polyester resin and solvent-based thermosetting coating composition comprising said resin and blocked polyisocyanate crosslinking agent. The coating composition may be formulated as a hot sprayable, high solids coating composition suitable for use as chip resistant automotive vehicle primer suitable for use on body panel areas subject to chipping by stones, gravel and other road debris. Alternatively, the composition may be formulated as a high solids composition sprayable with conventional spraying equipment. The hydroxy functional urethane modified polyester resin is the product of polymerization of lactone monomers in the presence of hydroxy-containing urethane modified polyester precursor. The polymerization reaction mixture comprises between about 10 and about 80 weight percent the hydroxy-containing urethane modified polyester precursor and between about 90 and about 20 weight percent lactone monomers.
    Type: Grant
    Filed: December 24, 1985
    Date of Patent: March 29, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Panagiotis I. Kordomenos, Andrew H. Dervan, Tab Semanision
  • Patent number: 4734508
    Abstract: A process is provided for preparing 4-hydroxy-4-phenyl-proline derivatives of the structure ##STR1## wherein R.sub.1 is a nitrogen protecting group such as benzoyl, benzyloxycarbonyl, t-butoxycarbonyl, benzyl, benzhydryl, trityl, acetyl, trifluoromethylacetyl, sulfonamides, and the like and wherein X is OR.sub.2 and R.sub.2 is hydrogen or an acid protecting group such as lower alkyl, aryl-lower alkyl or a metal ion, such as Na or K, or X is NR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 may be the same or different and are hydrogen, lower alkyl, aryl or arylalkyl, or R.sub.3 and R.sub.4 together with the nitrogen to which they are attached form a 5-, 6- or 7-membered ring. The process includes the steps of forming triphenylcerium [(C.sub.6 H.sub.5).sub.3 Ce], for example, by reacting cerium trichloride (CeCl.sub.3) with phenyllithium, and reacting the triphenylcerium with the keto acid ##STR2## in the presence of an inert organic solvent such as tetrahydrofuran.
    Type: Grant
    Filed: May 1, 1987
    Date of Patent: March 29, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: John K. Thottathil
  • Patent number: 4732515
    Abstract: For chip-removing machining of the contact surfaces of rails 1, a stationary system is used which to attain high machining output as well as good surface quality uses a rotating, internally toothed milling ring 2, the flight circle of which generates the normally elliptical contact surface profile of the rail 1, in a position inclined with respect to the longitudinal axis of the rail. To avoid reproducing the ridged defects 18 of the contact surface, at least one conical supporting roller 17 is used in the machining region, its elliptical contact arc being designed with a substantially longer radius of curvature than the amplitude length of the ridges.
    Type: Grant
    Filed: October 29, 1986
    Date of Patent: March 22, 1988
    Assignee: Dr. Techn. E. Linsinger & Co Gesellschaft m.b.H.
    Inventor: Josef Pomikacsek
  • Patent number: 4732726
    Abstract: A plastic injection mold having means therein for holding an insert to be secured in the formed product. A pair of complimentary sized mold sections are movable together, one mold section having a pin fixedly mounted thereto and extending toward a second pin slidably mounted in the second mold section and aligned with the first pin. In the preferred embodiment, a helical spring contacting the slidable pin urges the pin outwardly to initially hold an insert. As the mold closes, the pins are contacted together with the spring being yieldable to allow retraction of one pin and the transfer of the insert mounted thereon onto the second pin. In an alternate embodiment, the retractable pin is fixedly mounted to a movable plate having a spring loaded leg depending therefrom with the leg being contactable by the mold sections as the mold is closed for the retraction of the slidable pin and the transfer of the insert.
    Type: Grant
    Filed: September 18, 1986
    Date of Patent: March 22, 1988
    Assignee: E. W. Mold & Tool Co., Inc.
    Inventor: Walter A. Grannen, III
  • Patent number: 4732259
    Abstract: A continuous apron type sortation conveyor having carton pushers which travel with and crosswise of the apron is provided with branch lines arranged in pairs directly opposite each other along the main line to which oppositely angled guide tracks for the pushers lead from positions adjacent the center of the conveyor. The successive carton pushers enter the upstream end of the conveyor on the opposite side of the apron from the side to which they will deliver the carton assigned thereto, and immediately thereafter, they are caused to travel approximately half-way across the apron to a centered position thereon, while at the same time pushing the carton assigned thereto to a position close to the side edge of the apron from which they are to be delivered to a branch line.
    Type: Grant
    Filed: July 9, 1986
    Date of Patent: March 22, 1988
    Assignee: The E. W. Buschman Company
    Inventors: Thomas C. Yu, Robert K. Vogt
  • Patent number: 4733111
    Abstract: The basic element provided by the invention carries out the basic logic functions of storage and/or transfer of the data applied at the input, typical of a latch. Two ways of embodiment of the basic element having active phase at the high and low level of the clock signal are described. The basic element presents a transfer-gate transistor at the input controlled by the clock signal, followed by an inverter at whose signal leads two positive feedback networks are connected, one of which controlled by the clock signal, to stabilize the logic levels (FIG. 1).
    Type: Grant
    Filed: May 30, 1986
    Date of Patent: March 22, 1988
    Assignee: Cselt--Centro Studi e Laboratori Telecomunicazioni S.p.A.
    Inventors: Mario Fassino, Guido Ghisio
  • Patent number: 4732213
    Abstract: A process for selectively plugging permeable zones in subterranean formations or for plugging subterranean leaks which comprises injecting into the permeable zone or the site of the subterranean leak an aqueous solution containing 1 to 70 weight percent of a non-aggregated colloidal silica sol having a particle size in the range between 4 and 100 nm and a pH in the range between about 1 and 10, and causing said solution to gel in said zone or at said site.
    Type: Grant
    Filed: September 15, 1986
    Date of Patent: March 22, 1988
    Assignees: Conoco Inc., E. I. Du Pont de Nemours and Company
    Inventors: Karl E. Bennett, John L. Fitzjohn, Richard A. Harmon, Paul C. Yates, Jr.
  • Patent number: 4732864
    Abstract: Conjugates of target-seeking biologically active molecules and metallothionein in which all or part of the metal in the metallothionein is suitable for diagnostic or therapeutic applications.
    Type: Grant
    Filed: October 6, 1983
    Date of Patent: March 22, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Glen L. Tolman
  • Patent number: 4732558
    Abstract: An injection mold assembly for formation of thin walled multi-partitioned plastic containers. An array of cantileveredly mounted and spaced apart cores are extendable into a female mold assembly which includes a pair of side cavity cams and end cavity cams closeable upon the array, but spaced therefrom to form the plastic container therebetween. A plurality of side locking wedge shaped fingers are extendable into the slots spacing the cores apart. The fingers are arranged to extend into the opposite sides of the array of cores in a direction perpendicular to the longitudinal axis of the array spacing the cores apart while plastic is injected into the assembly by injectors mounted to the female mold. A pair of end pushers contact the two outermost cores in the array limiting outward movement of the cores during the injection step. The end pushers likewise extend in a direction perpendicular to the longitudinal axis of the array.
    Type: Grant
    Filed: September 8, 1986
    Date of Patent: March 22, 1988
    Assignee: E-W Mold & Tool Co., Inc.
    Inventor: Walter A. Grannen, III
  • Patent number: 4733169
    Abstract: A frequency detector completely implemented with digital logic circuitry is disclosed. The frequency detector hereof employs a unique phase locked loop digitally implemented with asynchronous ripple counters, and a digitally implemented amplitude comparator and signal integrator. The detector is especially adapted for implementation in CMOS hardware, or similar hardware having low current drain characteristics. The selectivity of the detector can be set to a narrow bandwidth for excellent noise discrimination characteristics.
    Type: Grant
    Filed: April 15, 1986
    Date of Patent: March 22, 1988
    Assignee: E. F. Johnson Company
    Inventor: Mervin L. Grindahl
  • Patent number: 4732504
    Abstract: A flat flexible ballpoint pen is formed from two foil strips which are bonded together along their peripheries except for one end through which the writing cartridge is inserted. A case also formed from flexible strips in a similar manner can accommodate the body carrying the cartridge.
    Type: Grant
    Filed: September 12, 1986
    Date of Patent: March 22, 1988
    Assignee: Design Machine S.N.C. di Adalberto Brunetti e Danilo Telli
    Inventor: Rolando D. Telli
  • Patent number: 4732850
    Abstract: A biological indicator is made of a vial which contains a "spore dot", a nutrient solution in a frangible ampoule, and means for positioning the spore dot and for breaking the ampoule to release the nutrient solution when the cap of the vial is fully pressed on. The nutrient solution typically contains a pH indicator to determine whether all active spores on the strip were killed by a sterilization process which takes place prior to breaking the ampoule.
    Type: Grant
    Filed: July 5, 1985
    Date of Patent: March 22, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: James R. Brown, Steven T. Buglino
  • Patent number: 4732955
    Abstract: Mercury compounds which are useful as co-catalysts in group transfer polymerization are disclosed.
    Type: Grant
    Filed: September 29, 1986
    Date of Patent: March 22, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Ira B. Dicker
  • Patent number: 4732696
    Abstract: Monoglycosides have been found to increase the viscosity of aqueous-based detergent compositions containing anionic surfactants.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: March 22, 1988
    Assignee: A. E. Staley Manufacturing Company
    Inventor: Allen D. Urfer
  • Patent number: 4732604
    Abstract: This invention relates to certain sulfonylurea compounds having substituents ortho to the sulfonylurea linkage that includes a 3- or 4- membered carbocyclic ring, a saturated 5- or 6- membered carbocyclic ring or a heterocyclic ring which contains 1 heteroatom selected from O, S and NR.sub.3, agriculturally suitable compositions thereof and a method of their use as herbicides or plant growth regulants.
    Type: Grant
    Filed: February 24, 1987
    Date of Patent: March 22, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: James V. Hay, Barry A. Wexler, Donna F. Zimmerman
  • Patent number: 4732831
    Abstract: Xeroprinting process involving imagewise exposing a photopolymer master, charging on a conductive support, toning with dry or liquid electrostatic toner, and transferring to another surface. Photopolymer systems comprising preferred combinations of polymeric binders, ethylenically unsaturated monomers. HABI initiators and chain transfer agents.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: March 22, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: James Riesenfeld, William Bindloss, Graciella Blanchet, Rolf Dessauer, Alan S. Dubin