Abstract: A method for producing a hyperpolarized sample for use in a magnetic resonance investigation has the following steps: a) providing a solid sample (50), containing long T1 nuclei and short T1 nuclei in the same molecules (51); b) hyperpolarizing the short T1 nuclei in the solid sample (50); c) transforming the solid sample (50) into a liquid sample (52); and d) transferring the polarization of the short T1 nuclei to the long T1 nuclei within the molecules in the liquid sample (52) by Cross Polarization. The method can provide samples with hyperpolarized long T1 nuclei, in particular 13C or 15N, in a simple and efficient way.

Abstract: A method for producing hyperpolarized sample material for use in magnetic resonance investigations involves preparing a target material containing high ? nuclei with a short T1, a polarizing agent with a broad EPR line, and low ? nuclei with a long T1. The polarizing agent in the target material is irradiated with microwave radiation, wherein the target material is at a cryogenic temperature and exposed to a static magnetic field B0?4.0 T, thus polarizing the high ? nuclei by DNP, and the polarization is transferred from the high ? nuclei to the low ? nuclei by Cross Polarization. A dissolved sample material is prepared containing the hyperpolarized low ? nuclei from the target material. Nuclei with a long longitudinal relaxation time T1 can thereby be quickly hyperpolarized to a high polarization level.

Abstract: The invention relates to substituted ullazine and analogs of ullazine as sensitizers for dye-sensitized solar cells (DSSCs) and other photoelectrochemical and/or optoelectronic devices. The sensitizers may comprise donor substituents and/or acceptor substituents, besides an anchoring group suitable for attaching the sensitizer on a semiconductor surface. DSSCs based on this type of sensitizers exhibit high power conversion efficiencies.

Abstract: The invention relates to a system and a method for assessment of walking and miming gait in human. The method is preferably based on the fusion of a portable device featuring inertial sensors and several new dedicated signal processing algorithms: the detection of specific temporal events and parameters, 5 optimized fusion and de-drifted integration of inertial signals, automatic and online virtual alignment of sensors module, 3D foot kinematics estimation, a kinematic model for automatic online heel and toe position estimation, and finally the extraction of relevant and clinically meaning-full outcome parameters. Advantageously including at least one wireless inertial module attached to foot, the system provides common spatio-temporal parameters (gait cycle time, stride length, and stride velocity), with the 10 advantage of being able to work in unconstrained condition such as during turning or running.

Abstract: The present invention relates to a method, such as a surgical method for assisting a surgeon for placing screws in the spine using a robot attached to a passive structure. The present invention also related to a method, such as a surgical method for assisting a surgeon for removing volumes in the body of a patient using a robot attached to a passive structure and to a device to carry out said methods. The present invention further concerns a device suitable to carry out the methods according to the present invention.

Abstract: A database system maintains a feature set of a modern database system while operating directly on raw data files. Systems may use an adaptive indexing mechanism that maintains positional information to provide efficient access to raw data files, a flexible caching structure, and techniques for selective parsing and selective tokenizing. In doing so, possible performance bottlenecks associated with repeated parsing, tokenizing, and expensive data type conversion costs can be overcome.

Abstract: A device is provided for managing heat in an optical element, including: the optical element; a material at a reference temperature; and an intermediate gas layer located directly between the reference-temperature material and the optical element, the intermediate gas layer being located on at least a portion of the thickness thereof in a temporary diffusion state defined by a thickness of the intermediate gas layer, such that the ratio of the mean free path of the gas molecules in the intermediate gas layer over said thickness is between 0.1 and 10. The thickness of the intermediate gas layer is between 10 ?m and 5 mm. A corresponding heat-management method is implemented in the device for managing the temperature of an optical element.

Abstract: An encoding/decoding apparatus and method using a low-density parity-check code (LDPC code) is disclosed. Basic column group information, serving as a set of information regarding positions of rows with weight 1, is extracted from a reference column in each column group of a predetermined parity-check matrix. Column group information transforms the positions of rows with weight 1 into positions whose lengths are within a required parity length. A parity-check matrix is generated according to the generated column group information. Data is encoded or decoded based on the generated parity-check matrix.

Abstract: In this invention, we propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients' genomic data. Assuming the whole genome sequencing is done by a certified institution, we propose to store patients' genomic data encrypted by a patient's public keys at a Storage and Processing Unit (SPU). A part of the corresponding private key is also stored on the SPU. At the time of the test by a Medical Unit (MU), the patient provides the second part of the private key to the MU. A test with its associated markers is determined by the MU and sent to the SPU. The test is carried out on the encrypted values thanks to homomorphic operation and returned back to the MU. The latter uses the second part of the private key to access the result.

Abstract: A method for displaying an image viewable by an eye, the image being projected from a portable head worn display, comprises steps of: emitting a plurality of light beams of wavelengths that differ amongst the light beams; directing the plurality of light beams to a scanning mirror; modulating in intensity each one of the plurality of light beams in accordance with intensity information provided from the image, whereby the intensity is representative of a pixel value within the image; scanning the plurality of light beams in two distinct axes with the scanning mirror to form the image; and redirecting the plurality of light beams to the eye using a holographic optical element acting as a reflector of the light beams, whereby the redirecting is dependent on the wavelength of the light beam, to create for each light beam an exit pupil at the eye that is spatially separated from the exit pupils of the other light beams.

Abstract: The present invention relates to an underwater propelling device (10) i a stator (20) comprising circumferential arrayed coils (35) and being adapted to generate a controlled electromagnetic field along an axial direction, a shaftless propellant rotor (30) comprising: at least two magnetized ring-shaped plates, respectively an upper magnetized plate (31) and a lower magnetized plate (32), coaxially spaced-apart along said axial direction and perpendicular thereto such that said circumferential arrayed coils (35) are positioned therebetween, each plate (31, 32) defining a central aperture (31a, 32a) and having a circumferential array of radially extended magnetized poles (34) embedded therein, said magnetized poles (34) generating a magnetic field which interacts with the electromagnetic field of the stator (20) so as to cause the rotation of said plates (31, 32) about a central axis (ZZ?) parallel to said axial direction, at least one ring-shaped propeller (33) defined by its outer periphery and its inner

Abstract: The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formula (I) and pharmaceutically acceptable salts, solvates, hydrates, regioisomeric and polymorphic forms thereof, processes for manufacturing of them, the use of them, as well as pharmaceutical compositions containing at least one of them as pharmaceutically active agent(s) together with pharmaceutically acceptable carrier, excipient and/or diluents, especially for the inhibition of polo-like kinases (PLKs) and the treatment of cancer. Said 4-pyrimidinylamino-benzenesulfonamide compounds have been also identified as new drug candidates for the prevention and/or treatment of infectious diseases like bacterial diseases e.g. tuberculosis, including the currently multidrug-resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) as well as for preventing tuberculosis.

Abstract: Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an supportive backing layer. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as along a region of a cortex of a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.

Abstract: A simple method to denoise ratio images in magnetic resonance imaging, includes generating a MRI sequence provided for acquiring data from an object to be imaged, wherein the MRI sequence is configured for generating at least two different standard images, respectively a first standard image and a second standard image, acquiring the two different standard images, and combining the two different standard images in a ratio image. The ratio image is obtained by calculating a ratio of the first standard image and the second standard image that is tunable by a parameter ? wherein the parameter ? is automatically chosen for maximizing the negentropy of the ratio image.

Abstract: An indoor localization method for estimating the location of nodes (n1, n2), at least one node (n1) being connected to at least another node (n2) by at least two different channels (ch1, ch1?), comprising the following steps: measuring a distance between the connected nodes, for each channel, building a Euclidean Distance Matrix (EDM) based on the measured distances, estimating the location of the nodes (n1, n2) based on the built Euclidean Distance Matrices.

Abstract: Method for measuring a distribution of a physical variable in a region, comprising the step of: measuring an average value of the physical variable along each of a plurality of lines in said region; estimating the distribution of the physical variable in said region on the basis of the plurality of average values of the physical variable along the plurality of lines.

Abstract: A computer implemented method for encrypting one or more files and wrapping them in an HTML document. The HTML document contains the encrypted files, the necessary code to decrypt the files, as well as user interface code to receive a passphrase input from a user. The HTML document can be opened using any modern web browser, to obtain the original files using the same passphrase with which the encryption was performed. This offers a convenient way of sharing encrypted files via email or cloud file sharing services using a platform independent file format (without having to install any additional software).

Abstract: A determination is made regarding whether to merge two symbolic analysis states. A first state corresponds to a first path through a program to a program location and a second state corresponds to a second path through the program to the program location. A set of variables of the program at the program location is determined. For each variable in the set: a) a first value of the variable in the first state is determined; b) a second value of the variable in the second state is determined; and c) a determination is made, based on the first and second values, regarding whether merging the first and second states would be advantageous. A determination is made, responsive to determining that merging the first state and the second state would not be advantageous for at least one variable in the set, not to merge the first state and the second state.

Abstract: In this invention, we propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients' genomic data. Assuming the whole genome sequencing is done by a certified institution, we propose to store patients' genomic data encrypted by a patient's public keys at a Storage and Processing Unit (SPU). A part of the corresponding private key is also stored on the SPU. At the time of the test by a Medical Unit (MU), the patient provides the second part of the private key to the MU. A test with its associated markers is determined by the MU and sent to the SPU. The test is carried out on the encrypted values thanks to homomorphic operation and returned back to the MU. The latter uses the second part of the private key to access the result.

Abstract: A recommender system comprising at least one computing device which comprises one or more processors and one or more computer-readable storage media operatively coupled to at least one of the processors, wherein said computing device performs a method of assigning a user to one group of a set of groups, said set of groups comprising at least two distinct groups, and a method of providing said user with at least one recommendation.