Patents Assigned to ETH Zurich
  • Patent number: 11257276
    Abstract: Techniques are disclosed for generating digital faces. In some examples, a style-based generator receives as inputs initial tensor(s) and style vector(s) corresponding to user-selected semantic attribute styles, such as the desired expression, gender, age, identity, and/or ethnicity of a digital face. The style-based generator is trained to process such inputs and output low-resolution appearance map(s) for the digital face, such as a texture map, a normal map, and/or a specular roughness map. The low-resolution appearance map(s) are further processed using a super-resolution generator that is trained to take the low-resolution appearance map(s) and low-resolution 3D geometry of the digital face as inputs and output high-resolution appearance map(s) that align with high-resolution 3D geometry of the digital face. Such high-resolution appearance map(s) and high-resolution 3D geometry can then be used to render standalone images or the frames of a video that include the digital face.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: February 22, 2022
    Assignees: DISNEY ENTERPRISES, INC., ETH ZURICH, (EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH)
    Inventors: Prashanth Chandran, Dominik Thabo Beeler, Derek Edward Bradley
  • Publication number: 20220049232
    Abstract: The present invention relates to a method for recording a transcriptome of a cell, the method comprising the steps of: providing a test cell comprising: a first transgene nucleic acid sequence encoding a fusion protein comprising a reverse transcriptase polypeptide and a Cas1 polypeptide and a second transgene nucleic acid sequence encoding a Cas2 polypeptide, wherein said first transgene nucleic acid sequence and said second transgene nucleic acid sequence are under transcriptional control of an inducible promoter sequence, and a third transgene nucleic acid sequence comprising a CRISPR direct repeat (DR) sequence; wherein said CRISPR direct repeat sequence is specifically recognizable by a RT-Cas1-Cas2 complex formed by the expression products of said first transgene nucleic acid sequence and said second transgene nucleic acid sequence, exposing said test cell to conditions under which expression of said first transgene nucleic acid sequence and said second transgene nucleic acid sequence is induced, wherei
    Type: Application
    Filed: September 11, 2019
    Publication date: February 17, 2022
    Applicant: ETH ZÜRICH
    Inventors: Randall Jeffrey PLATT, Florian SCHMIDT
  • Patent number: 11244723
    Abstract: The invention is directed to a device for high-dimensional encoding of a plurality of sequences of quantitative data signals. The device comprises a plurality of input channels for receiving the plurality of sequences of quantitative data signals and an encoding unit. The encoding unit is configured to perform a temporal high-dimensional encoding of n-grams of the plurality of sequences of quantitative data signals; thereby creating a plurality of temporally encoded hypervectors for the plurality of input channels. The encoding unit is further configured to perform a spatial high-dimensional encoding of the plurality of temporally encoded hypervectors, thereby creating a temporally and spatially encoded hypervector. The device further comprises a configuration controller. The configuration controller is adapted to configure the high-dimensional encoding in dependence on one or more hyperparameter values.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: February 8, 2022
    Assignees: International Business Machines Corporation, ETH ZURICH
    Inventors: Kumudu Geethan Karunaratne, Manuel Le Gallo-Bourdeau, Giovanni Cherubini, Abu Sebastian, Abbas Rahimi, Luca Benini
  • Publication number: 20220024761
    Abstract: A process for the production of syngas, comprising the steps of generating hydrogen and/or carbon monoxide from a hydrocarbon gas by contacting said hydrocarbon gas with a metal oxide in a first non-stoichiometric state MxOy-? such as to reduce said metal oxide in a first non-stoichiometric state MxOy-? towards a second non-stoichiometric state MxOy-?; generating hydrogen and/or carbon monoxide from a regenerating gas by contacting the metal oxide in the second non-stoichiometric state MxOy-? with said regenerating gas such as to oxidize the metal oxide in the second non-stoichiometric state MxOy-? towards the first non-stoichiometric state MxOy-?; characterized in that the ?>? and ?>0 and ?<y.
    Type: Application
    Filed: September 17, 2019
    Publication date: January 27, 2022
    Applicant: ETH ZURICH
    Inventors: Simon ACKERMANN, Paul DIERINGER, Philipp FURLER, Aldo STEINFELD, Brendan BULFIN
  • Publication number: 20220018921
    Abstract: A magnetic resonance (MR) apparatus comprises magnet means for generating a main magnetic field in a sample region, encoding means for generating encoding magnetic fields superimposed to the main magnetic field, RF transmitter means for generating MR radiofrequency fields, driver means for operating said encoding means and RF transmitter means to generate superimposed time dependent encoding fields and radiofrequency fields according to an MR sequence for forming images or spectra; and acquisition means for acquiring an MR signal from said object. The magnet means comprise a primary magnetic field source providing a static magnetic field B0 and at least one secondary magnetic field source providing an adjustable magnetic field B?.
    Type: Application
    Filed: August 1, 2021
    Publication date: January 20, 2022
    Applicants: UNIVERSITAET ZUERICH, ETH Zurich
    Inventors: David Brunner, Simon Gross, Klaas Pruessmann
  • Patent number: 11226763
    Abstract: The invention is notably directed at a device for high-dimensional computing comprising an associative memory module. The associative memory module comprises one or more planar crossbar arrays. The one or more planar crossbar arrays comprise a plurality of resistive memory elements. The device is configured to program profile vector elements of profile hypervectors as conductance states of the resistive memory elements and to apply query vector elements of query hypervectors as read voltages to the one or more crossbar arrays. The device is further configured to perform a distance computation between the profile hypervectors and the query hypervectors by measuring output current signals of the one or more crossbar arrays. The invention further concerns a related method and a related computer program product.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: January 18, 2022
    Assignees: International Business Machines Corporation, ETH ZURICH (EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH)
    Inventors: Manuel Le Gallo-Bourdeau, Kumudu Geethan Karunaratne, Giovanni Cherubini, Abu Sebastian, Abbas Rahimi, Luca Benini
  • Publication number: 20220009875
    Abstract: A process for preparing a nitrated compound, including the step of reacting a compound (A) including at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein the heteroaromatic ring includes at least one heteroatom selected from the group consisting of oxygen, sulfur, phosphor, selenium and nitrogen, with a compound of formula (I) wherein Y is selected from the group consisting of hydrogen and nitro.
    Type: Application
    Filed: October 24, 2019
    Publication date: January 13, 2022
    Applicant: ETH ZURICH
    Inventors: Dmitry KATAYEV, Kun ZHANG, Roxan CALVO
  • Publication number: 20220009895
    Abstract: N-nitrosaccharin of the general formula (I), wherein R is either a hydrogen (H) or a nitro group (NO2), its preparation and its use as nitrating agent.
    Type: Application
    Filed: October 24, 2019
    Publication date: January 13, 2022
    Applicant: ETH ZURICH
    Inventors: Dmitry KATAYEV, Kun ZHANG, Roxan CALVO
  • Publication number: 20220008870
    Abstract: The invention relates to a method for a fabrication of a pore comprising membrane and a pore comprising membrane. The pore comprising membrane (1) comprises at least a porous metallic layer (3) on a porous substrate (6), wherein the porous metallic layer (3) is connected to the porous substrate (6) and the pores (4) of the metallic layer (3) overlap at least partially with the pores (7) of the porous substrate (6). The method comprises at least the following steps: i) deposition of the metallic layer (3) onto a support material (2), wherein the deposited metallic layer (3) forms a plurality of feedthroughs, in particular a percolation network on the support material (2), ii) removal of the support material (2), iii) connecting of the metallic layer (3) with the porous substrate (6) such that pores (4) of the metallic layer (3) overlap at least partially with the pores (7) of the porous substrate (6).
    Type: Application
    Filed: November 14, 2019
    Publication date: January 13, 2022
    Applicant: ETH ZURICH
    Inventors: Hyung Gyu PARK, Roman WYSS
  • Patent number: 11219649
    Abstract: The present invention relates to novel compositions comprising specific consortia of living bacteria strains; to the manufacturing of such compositions, particularly by co-cultivation; and to the use of such compositions in pharmaceutical applications, such as the treatment of diseases associated with intestinal microbiota dysbiosis, particularly intestinal infections such as CDI (Clostridium difficile infection) and IBD (Inflammatory bowel diseases). When compared to the traditional FMT therapy () the inventive compositions () are more efficient and safer as demonstrated on an acute colitis model and therefore more appropriate for therapeutic use.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: January 11, 2022
    Assignees: ETH Zurich, UNIVERSITÄT ZÜRICH
    Inventors: Christophe Lacroix, Tomas De Wouters, Gerhard Rogler, Christophe Chassard, Laura Berchtold, Fabienne Kurt, Michael Martin Scharl, Marianne Rebecca Spalinger, Markus Reichlin, Florian Nils Rosenthal, Marco Meola
  • Patent number: 11222466
    Abstract: Techniques are disclosed for changing the identities of faces in video frames and images. In embodiments, three-dimensional (3D) geometry of a face is used to inform the facial identity change produced by an image-to-image translation model, such as a comb network model. In some embodiments, the model can take a two-dimensional (2D) texture map and/or a 3D displacement map associated with one facial identity as inputs and output another 2D texture map and/or 3D displacement map associated with a different facial identity. The other 2D texture map and/or 3D displacement map can then be used to render an image that includes the different facial identity.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: January 11, 2022
    Assignees: Disney Enterprises, Inc., ETH Zürich (Eidgenössische Technische Hochschule Zürich)
    Inventors: Jacek Krzysztof Naruniec, Derek Edward Bradley, Thomas Etterlin, Paulo Fabiano Urnau Gotardo, Leonhard Markus Helminger, Christopher Richard Schroers, Romann Matthew Weber
  • Patent number: 11215687
    Abstract: A method for generating an image data set of an image area located in a measurement volume of a magnetic resonance system comprising a gradient system and an RF transmission/reception system, comprises the following method steps: —reading out k-space corresponding to the imaging area, by: (a) activating a frequency encoding gradient in a predetermined spatial direction and with a predetermined strength G0 by means of said gradient system, (b) after the activated frequency encoding gradient achieves its strength G0, radiating a non-slice-selective RF excitation pulse by means of said RF transmission/reception system, (c) after a transmit-receive switch time ?tTR following the radiated excitation pulse, acquiring FID signals with said RF transmission/reception system and storing said FID signals as raw data points in k-space along a radial k-space trajectory that is predetermined by the direction and strength G0 of the frequency encoding gradient, (d) repeating (a) through (c) with respectively different freque
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: January 4, 2022
    Assignees: ETH Zurich, UNIVERSITAET ZUERICH
    Inventors: Romain Froidevaux, Markus Weiger
  • Patent number: 11207342
    Abstract: The invention relates to double stranded ribonucleic acid (dsRNA) agents and compositions targeting a High Density Lipoprotein Binding Protein (Hdlbp/Vigilin) gene, as well as methods of inhibiting expression of Hdlbp/Vigilin and methods of treating subjects having a disorder of lipid metabolism, such as mixed hyperlipidemia, hypertriglyceridemia or hypercholesterolemia, using such dsRNA agents and compositions.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: December 28, 2021
    Assignees: Alnylam Pharmaceuticals, Inc., ETH Zurich
    Inventors: Muthiah Manoharan, Markus Stoffel, Mehrpouya Balaghy Mobin
  • Patent number: 11207831
    Abstract: A 3D printed core-shell filament comprises an elongated core radially surrounded by an outer shell with a barrier layer in between, where the elongated core comprises a ductile polymer and the outer shell comprises a stiff polymer having a Young's modulus higher than that of the ductile polymer. A lightweight lattice structure may comprise a plurality of the 3D printed core-shell filaments deposited in layers.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: December 28, 2021
    Assignees: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, ETH ZURICH (SWISS FEDERAL INSTITUTE OF TECHNOLOGY)
    Inventors: Jennifer A. Lewis, Jochen Mueller, Jordan R. Raney, Kristina Shea
  • Patent number: 11210774
    Abstract: According to one implementation, a pixel error detection system includes a hardware processor and a system memory storing a software code. The hardware processor is configured to execute the software code to receive an input image, to mask, using an inpainting neural network (NN), one or more patch(es) of the input image, and to inpaint, using the inpainting NN, the masked patch(es) based an input image pixels neighboring each of the masked patch(es). The hardware processor is configured to further execute the software code to generate, using the inpainting NN, a residual image based on differences between the inpainted masked patch(es) and the patch(es) in the input image and to identify one or more anomalous pixel(s) in the input image using the residual image.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: December 28, 2021
    Assignees: Disney Enterprises, Inc., ETH Zürich (EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH)
    Inventors: Christopher Richard Schroers, Abdelaziz Djelouah, Sutao Wang, Erika Varis Doggett
  • Patent number: 11184089
    Abstract: According to the present invention there is provided a receiver device comprising, a first electrode (3) which can capacitive couple to an electrode of a transmitter device; a second electrode (5) which can capacitive couple to said electrode of said transmitter device; an energy harvesting circuit (7), which comprises a first capacitor (9), wherein said first electrode (3) is electrically connected to the energy harvesting circuit (7) so that energy from a signal which was transmitted from the electrode of the transmitter device and received at the first electrode (3), can be used to increase voltage across the first capacitor (9); and a comparator (15), wherein the first capacitor (9) is electrically connected to a positive supply input terminal (15c) of the comparator (15) so that voltage across the first capacitor (9) can be used to power the comparator (15); a demodulator circuit (11) wherein said second electrode (5) is electrically connected to the demodulator circuit (11); a first filter circuit (17),
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: November 23, 2021
    Assignee: ETH Zürich
    Inventor: Michele Magno
  • Patent number: 11179427
    Abstract: The present invention relates to compositions, particularly baby food compositions, including living propionic acid-producing bacteria, preferably lactate-utilizing propionic acid-producing bacteria, their manufacture and use in the treatment of digestive diseases, particularly for treatment of infantile colic.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: November 23, 2021
    Assignee: ETH ZURICH
    Inventors: Christophe Chassard, Christophe Lacroix, Christian Braegger, Vanesa Natalin Rocha Martin
  • Patent number: 11180738
    Abstract: The present invention is directed to all aspects of novel methyl transferase enzymes that methylate backbone amides of (poly)peptides. The present invention also relates to nucleic acids encoding these enzymes as well as corresponding vectors and host cells comprising these. Moreover, the present invention encompasses the use of said enzymes for modifying (poly)peptides as well as corresponding methods. Also, the present invention pertains to further novel enzymes for modifying (poly)peptides derived from the omphalotin gene cluster of O. olearius and the homologous gene clusters from D. bispora, L. edodes and F. mediterranea as well as related aspects.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: November 23, 2021
    Assignee: ETH ZURICH
    Inventors: Markus Aebi, Markus Kunzler, Jorn Piel, Michael Freeman, Niels Van Der Velden, Noemi Kalin
  • Publication number: 20210356396
    Abstract: The present invention refers to Biodegradable, biocompatible, water-suspensable nanoparticle (1), for generating a second- or third-harmonic light signal upon illumination, as well as a method for preparing an aqueous suspension comprising said nanoparticle, a method for second-harmonic generation imaging of the nanoparticle (1) as and a use of the nanoparticle (1) for second-harmonic generation imaging. The nanoparticle (1) according to the invention comprises —a shell layer (2) comprising a biodegradable polymer (3), wherein the shell layer (2) encloses —a plurality (40) of oligopeptides (4), wherein the plurality (40) of oligopeptides (4) is structured such that a second-harmonic light signal is generated upon illumination of the nanoparticle (1) with light.
    Type: Application
    Filed: September 28, 2017
    Publication date: November 18, 2021
    Applicants: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V., ETH ZÜRICH
    Inventors: Periklis PANTAZIS, Ali Yasin SONAY, Daniel CRESPY, Katharina LANDFESTER
  • Publication number: 20210340526
    Abstract: The present invention relates to a cell comprising a first nucleic acid sequence encoding a first polypeptide fused to the N-terminus of a first variant of a histidine kinase comprising a DHp domain and a CA domain, wherein said first variant does not comprise a transmembrane domain, a second nucleic acid sequence encoding a second polypeptide fused to the N-terminus of a second variant of said histidine kinase comprising a DHp domain and a CA domain, wherein said second variant does not comprise a transmembrane domain, and a third nucleic acid sequence encoding a response regulatory protein specifically phosphorylatable by said DHp domain of said first or said second variant. The present invention further relates to uses of the cell of the invention.
    Type: Application
    Filed: October 15, 2019
    Publication date: November 4, 2021
    Applicant: ETH ZÜRICH
    Inventors: Alain MAZÉ, Yaakov BENENSON