Patents Assigned to Forschungszentrum Jülich GmbH
  • Publication number: 20190013512
    Abstract: A method for producing a ceramic cathode layer on an electrically conductive substrate includes applying a coating to the electrically conductive substrate, the coating being in a form of a suspension including at least one suspending agent and at least one ceramic material. The method further includes heating the coating in a reducing atmosphere such that the ceramic material is completely or in part reduced to a fusible reaction product, heating the coating in a reducing atmosphere to temperatures above the melting point of the reaction product so as to form a melt, densifying or sintering the coating in a reducing atmosphere at temperatures that are 100° C. greater than a melting temperature of the reaction product, and reoxidizing the densified or sintered coating in an oxidizing atmosphere in a temperature range of between 400° C. and 1,200° C.
    Type: Application
    Filed: December 9, 2016
    Publication date: January 10, 2019
    Applicant: Forschungszentrum Juelich GmbH
    Inventors: Juergen Dornseiffer, Hans-Gregor Gehrke, Manuel Krott, Olivier Guillon, Sven Uhlenbruck
  • Patent number: 10174097
    Abstract: The invention relates to peptides binding specifically to Abeta species for treating and/or diagnosing Alzheimer's disease.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: January 8, 2019
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Dieter Willbold, Janine Kutzsche, Antonia Klein
  • Patent number: 10170775
    Abstract: A method for producing a glass solder green seal, wherein a paste comprising a glass solder powder is applied to the surface of a screen, which on the bottom side and in the screen mesh comprises regions having a coating impermeable to the paste, and the paste is pushed through the screen onto a substrate and subsequently dried, wherein printing is carried out onto an intermediate carrier serving as the substrate, from which the dried glass solder green seal can be completely detached.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: January 1, 2019
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Dirk Federmann, Hans-Rainer Zerfass, Sonja-Michaela Gross-Barsnick
  • Patent number: 10167318
    Abstract: The present invention relates to novel D-enantiomeric A-beta-oligomer-binding peptides, homologs, fragments, parts and polymers thereof and use thereof.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: January 1, 2019
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Dieter Willbold, Susanne Aileen Funke, Oleksander Brener, Luitgard Nagel-Steger, Dirk Bartnik, Antonia Nicole Klein
  • Patent number: 10153343
    Abstract: A method for producing a tunnel field-effect transistor (TFET) having a source region, a channel region, and a drain region includes arranging an epitaxial layer on a silicon substrate; applying a gate arrangement having a gate electrode to the epitaxial layer, a gate dielectric being arranged between the gate electrode and the silicon substrate; forming a doped pocket region below the gate dielectric adjacent to the source region; forming a selectively silicidated region in the source region, the selectively silicidated region extending as far as to below a gate; and forming a counter-doped region doped in an opposite way to the pocket region adjacent to the pocket region in the source region by diffusion of dopants out of the silicidated region, as a result of which a tunnel junction parallel to the electric field lines of the gate electrode is achieved.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: December 11, 2018
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Qing-Tai Zhao, Siegfried Mantl, Sebastian Blaeser
  • Patent number: 10123530
    Abstract: The invention relates to the treatment of blood, blood products and organs for the removal and/or detoxification of amyloid-beta oligomers.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: November 13, 2018
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventor: Dieter Willbold
  • Patent number: 10096824
    Abstract: Storage material, for storing electrical energy by reduction or oxidation of an active component, comprises the active component in at least a reduced and/or oxidized form and a reactive framework structure that is capable of chemically integrating at least one form of the active component in the form of a mixed oxide or an alloy into the reactive framework structure during the charging or discharging process. In the case of an oxidic framework structure, said integration can occur by formation of at least one stable mixed oxide of the active component and an oxide from the framework structure. In the case of the metallic framework structure, said integration can occur by forming an alloy of active component and at least one metal of the framework structure.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: October 9, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Andreas Hospach, Norbert H. Menzler, Martin Bram, Hans Peter Buchkremer, Leszek Niewolak, Willem J. Quadakkers, Joanna Zurek
  • Patent number: 10088487
    Abstract: A method for the quantitative characterization of amyloid and/or aggregated peptides and/or proteins in a sample, comprising:—providing a sample, wherein the sample includes an amyloid and/or aggregated peptide and/or protein having at least one aggregate size and shape;—adding an active ingredient to be analyzed to the sample solution;—separating the amyloid and/or aggregated peptides and/or proteins are from one another according to their aggregate size and shape;—optionally completely denaturing the amyloid and/or aggregated peptides and/or proteins of a particular fraction into monomer building blocks;—determining the change in concentration of the peptide and/or protein building blocks in at least one fraction by comparison against control values without the active ingredient.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 2, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Luitgard Nagel-Steger, Oleksandr Brener, Lothar Gremer, Dieter Willbold
  • Patent number: 10074771
    Abstract: A single-photon source was developed and the source comprises at least one active solid body, which upon excitation with light haying photons which each have excitation energy, emits a single photon having lower emission energy within a predefined time period. The active solid body is disposed on a surface or an interface of an electrically operated light source for photons having the excitation energy, so that the solid body can be excited through this surface or interface. It was found that the ease of handling and the ability to miniaturize electrical primary light sources can thus advantageously be combined with the ability of the active solid body to emit exactly one photon. Since the active solid body emits only a single photon within a predefined time period, it is no longer a disadvantage if the light source that is used for excitation emits a large number of photons per unit of time. This opens a way to mass-produce single-photon sources, among other things.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: September 11, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Hilde Hardtdegen, Martin Mikulics
  • Patent number: 10053599
    Abstract: A method for polymerizing a composition including hydridosilanes and subsequently using the polymers to produce silicon containing layers, comprising the following steps: a) providing a substrate; b) providing a composition including at least one hydridosilane that is dissolved in at least one organic and/or inorganic solvent, or including at least one hydridosilane that is already present in liquid form without solvent, wherein the hydridosilanes comprise at least one linear and/or one branched hydridosilane of the general formula SinH2n+2, where n?3, and/or a cyclic hydridosilane of the general formula SinH2n, where n?3; c) polymerizing the composition from step b) by way of acoustic cavitation; and d) coating the surface of the substrate with reaction products from step c).
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: August 21, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventor: Andrew Paolo Cadiz Bedini
  • Patent number: 10030056
    Abstract: An agent for preventing and/or treating HIV and other viral infections. The agent in particular comprises at least one peptide, including an amino acid sequence, which is suitable for preventing fibrils associated with Alzheimer's disease, and/or homologs, fractions and parts thereof, so as to treat and/or prevent HIV and/or other viral infections.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: July 24, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Susanne Aileen Funke, Dieter Willbold, Heiner Schaal, Marek Widera
  • Patent number: 10024986
    Abstract: The invention relates to a neutron detector unit for neutrons, in particular thermal and cold neutrons, comprising a detector housing (7, 17, 27), cathode elements and a plurality of anode elements (5, 15, 25), wherein in order to form a volume detector unit the anode elements (5, 15, 25) and the cathode elements enable a three-dimensional spatial resolution for conversion events, characterized by a converter gas in the detector housing (7, 17, 27). According to the invention, in a neutron detector arrangement which includes at least one neutron detector unit the neutron detector unit (3, 13, 23) or at least one of the neutron detector units (3, 13, 23) is oriented in such a way that at least some of the anode elements (5, 15, 25) of the at least one neutron detector unit (3, 13, 23) extend at least predominantly in a longitudinal orientation parallel or almost parallel to the direction of travel of the neutrons (4) to be detected.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: July 17, 2018
    Assignees: Forschungszentrum Juelich GmbH, CDT Cascade Detector Technologies GmbH, Ruprecht-Karls-Universitaet Heidelberg
    Inventors: Peter Lennert, Martin Klein, Christian J. Schmidt, Werner Schweika
  • Patent number: 10006061
    Abstract: The invention relates to a lyase and a lyase-encoding DNA, to vectors containing the DNA and to a method for the asymmetric synthesis of (S)-phenylacetylcarbinol. According to the invention, a lyase is provided, in which tryptophan is replaced with an amino acid at position 543 in protein ApPDC-E469G, said protein being modified with respect to the wild type of Aceobacter pasteurianus, or in which it is less space-filling than tryptophan. According to the invention, deoxyribonucleic acids are furthermore provided, which encode the lyase. (S)-phenylacetylcarbinol can be produced with the lyase according to the invention from the educts benzaldehyde and pyruvate or acetaldehyde with an enantiomeric excess of at least 94%.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: June 26, 2018
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Doerte Rother, Martina Pohl, Torsten Sehl, Lisa Marx, Robert Westphal
  • Patent number: 9987191
    Abstract: A device and method for desynchronizing a patient's neuronal brain activity in which the neuron population is firing in a pathologically synchronized manner. The device includes a stimulation unit that generates an acoustic stimulation signal that includes both a first tone and a second tone. The first tone is provided to shift the phase of the neuronal brain activity of a first subpopulation of the neuron population relative to the phase of the neuronal brain activity of a second subpopulation of the neuron population when the first tone is acoustically received by the patient. Further, the second tone is provided to shift the phase of the neuronal brain activity of the second subpopulation relative to the phase of the neuronal brain activity of the first subpopulation when the second tone is acoustically received by the patient. As a result, the acoustic stimulation signal desynchronizes the stimulated neuron population.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: June 5, 2018
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventors: Peter A. Tass, Urban Schnell, Jean-Christophe Roulet, Oleksandr Popovych, Joel Niederhauser, Hans-Joachim Freund, Birgit U. Barnikol
  • Patent number: 9983160
    Abstract: An electrode array for the cyclic reduction and oxidation of a redox species in an electrolyte, wherein both electrodes are disposed on an insulating substrate and connected to a counter electrode for the application of a voltage, comprising: 1) a control electrode for reacting the redox species for cyclic electron transport between the electrodes: and b) a collector electrode disposed opposite the control electrode, wherein a layer structure composed of a second insulator and a charge transfer mediator disposed thereon is additionally disposed on the side of the collector electrode located opposite the insulating substrate for reacting the redox species. Two methods for operating the electrode array are disclosed.
    Type: Grant
    Filed: June 12, 2012
    Date of Patent: May 29, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Dirk Mayer, Yaqing Liu, Andreas Offenhaeusser
  • Patent number: 9890406
    Abstract: A method for producing cathine ((1S,2S)-norpseudoephedrine), in which, in a first reaction step, benzaldehyde is reacted with an acetyl donor according to formula (1), where R?H or COOH, by way of an (S)-selective lease to yield an enantiomer mixture according to formulas (2) and (3) and, in a second step, the compound according to formula (3) is reacted with an amine donor by way of an (S)-selective transaminase to yield (1S,2S)-norpseudoephedrine.
    Type: Grant
    Filed: May 17, 2014
    Date of Patent: February 13, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Doerte Rother, Martina Pohl, Torsten Sehl, Alvaro Gomez Baraibar
  • Patent number: 9884164
    Abstract: A device with a non-invasive first stimulation unit configured to generate first stimuli which, when administered to a patient, suppress a pathologically synchronous activity of neurons in at least one of the brain and the spinal cord of the patient, with a non-invasive second stimulation unit configured to generate at least one of optical, acoustic, tactile, vibratory, and thermal second stimuli, and with a control unit configured to control the first and second stimulation units, wherein the generation of the first and second stimuli takes place optionally in a first or a second operating mode, and the control unit is configured to control the first and second stimulation units in such a way that, in the first operating mode, the generation of at least 60% of the second stimuli is coupled in time to the generation of the first stimuli and, in the second operating mode, the generation of at least 60% of the second stimuli takes place without the generation of the first stimuli.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: February 6, 2018
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventor: Peter Alexander Tass
  • Patent number: 9872648
    Abstract: A method and a device for collecting data for posturography comprising a magnetizable body and an acceleration sensor are located on the platform, which magnetizable body and acceleration sensor are connected to a computer by means of an A/D converter. An electromagnet is located under the platform and is attached so as to be displaceable in two axes parallel to the plane of the platform, wherein the electromagnet is connected to an A/D converter and a power supply by means of a circuit, and a time-variable display, which is connected to the A/D converter, and a digital camera which are connected to the computer. By means of the method and the device it is now possible to standardize posturographic measurements, simultaneously detect the acceleration and the position of the platform, and more variably carry out provocations.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: January 23, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Mehmet Eylem Kirlangic, Martina Minnerop, Christian Spross, Boris Boeckem, Markus Paulzen, Manfred Bednarek, Silke Lux, Katrin Amunts
  • Patent number: 9865343
    Abstract: A method for reading out a resistive memory cell comprising two electrodes that are spaced from each other by an ion-conducting resistive material was developed, the memory cells being transferrable from a stable state having a higher resistance value (high resistive state, HRS) to a stable state having a lower resistance value (low resistive state, LRS) when a write voltage is applied.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: January 9, 2018
    Assignees: Forschungszentrum Juelich GmbH, Rheinisch-Westfaelische Technische Hochschule
    Inventors: Jan Van Den Hurk, Elke Linn, Rainer Waser, Ilia Valov
  • Publication number: 20170362281
    Abstract: The invention relates to mutant NQ-Rhodopsin having potassium pumping properties, nucleic acid constructs encoding same, expression vectors carrying the nucleic acid construct, cells comprising said nucleic acid construct or expression vector, and their respective uses.
    Type: Application
    Filed: December 23, 2015
    Publication date: December 21, 2017
    Applicants: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V., FORSCHUNGSZENTRUM JUELICH GMBH, CEA COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES
    Inventors: Ernst BAMBERG, Christian BAMANN, Vitaly POLOVINKIN, Valentin GORDELIY, Vitaly SHEVCHENKO, Ivan GUSHCHIN