Abstract: A device for examining a pathological interaction between different brain areas, including a stimulation unit, which administers identical stimuli to a patient in a sequential manner, wherein the stimuli stimulate neurons of the patient in the brain areas to be examined, a measuring unit for recording measurement signals that represent a neural activity of the stimulated neurons, and a control and analysis unit for controlling the stimulation unit and for analyzing the measurement signals. The control and analysis unit transforms the measurement signals into the complex plane, examines the distribution of the phases of stimuli of the measurement signals absorbed by the measuring unit in response to the stimuli delivered to the patient, and determines the probability, with which the phase distribution differs from a uniform distribution, in order to ascertain whether a pathological interaction between the brain areas exists.

Abstract: The invention relates to a metallic bipolar plate for use in an electrochemical cell, wherein the bipolar plate comprises an electrically conductive graphene-like coating. The graphene-like coating has a layer thickness between 10 nm and 1 ?m. Chemical synthesis is initially carried out to produce the graphene-like coating according to the invention comprising one or more at least partially reduced graphene oxide layers. Proceeding from graphite powder, a graphite oxide powder is initially produced, which is subsequently converted into a stable graphene oxide (GO) suspension by way of ultrasonic dispersion. By depositing this suspension on a metallic carrier substrate (bipolar plate), thin graphene oxide layers can then be applied and subsequently be reduced to obtain at least partially reduced graphene oxide (rGO), which is referred to as graphene-like. This coating advantageously has sufficient stability and the necessary electrical conductivity for use in an electrochemical cell.

Abstract: A method for optical transmission of a structure into a recording medium which can be transformed locally from a first undefined state into a second defined state by irradiating with photons from a photon source. The two states of the recording medium are manifested in different physical and/or chemical properties of the recording medium. At least one photon source having a photon flux of less than 104 photons per second is selected for the irradiation with the photons. It was recognized that with such a low photon flux especially fine structures can advantageously be transmitted into the recording medium without the irradiation having to be partially blocked by a mask. In this manner, for a given wavelength (energy) of the photons, structures can be transmitted that are considerably smaller than the width, defined by the diffraction limit, of the probability distribution for the locations at which the emitted photons are incident.

Abstract: Methods for determining the transfer function of a signal-processing system that do not require a known input signal. The methods are based on two representations 1(x) and I2(x) of an object, which the system has produced from differently scaled input signals originating from the object, or from a representation I1(x) of a first object and from a representation I2(x) of an object that is geometrically similar thereto but has been scaled differently. The representations are either given or are produced at the start of the method. According to the invention, the representations are transformed into a working space, and sections that relate to the same region of the object are selected in each case. The quotient of the functions corresponding to these two sections in the working space from which the unknown input signal comes makes it possible to clearly determine the transfer function sought. Various methods are indicated for this determination.

Abstract: A lyase has an amino acid sequence selected from SEQ ID NOs: 1, 2 and 3, wherein the amino acid isoleucine in position no. 468 in the protein ApPDC-E469G, which is modified with respect to the wild type from Acetobacter pasteurianus, is replaced by an amino acid which occupies less space than isoleucine.

Abstract: A high-frequency conductor having improved conductivity comprises at least one electrically conductive base material. The ratio of the outer and inner surfaces of the base material permeable by a current to the total volume of the base material is increased by a) dividing the base material perpendicularly to the direction of current into at least two segments, which are spaced from each other by an electrically conductive intermediate piece and connected both electrically and mechanically to each other, and/or b) topographical structures in or on the surface of the base material and/or c) inner porosity of at least a portion of the base material compared to a design of the base material in which the respective feature was omitted.

Abstract: A gyrator for AC signals was developed. This gyrator comprises a Hall effect material, means for permeating this Hall effect material with a magnetic field that is perpendicular to the plane or surface of the material, at least one input port for coupling an alternating current (I1; I2) into the Hall effect material, and at least one output port for outcoupling an output voltage (U2; U1) which is a measure of the Hall voltage generated by the incoupled alternating current. Each of these ports has at least two terminals, which are connected to the outside. At least one terminal of each port is connected to a connecting electrode, which is electrically insulated from the Hall effect material and forms a capacitor together with the Hall effect material. The alternating current is thus capacitively coupled into the Hall effect material, and the output voltage is capacitively coupled out of the Hall effect material.

Abstract: An electronic component comprising a Josephson junction and a method for producing the same are proposed. The component comprises a substrate having at least one step edge in the surface thereof and a layer made of a high-temperature superconducting material disposed thereon, wherein this layer, at the step edge, has a grain boundary that forms the one or two weak links of the Josephson junction. On both sides of the step edge, the a and/or b crystal axes in the plane of the high-temperature superconducting layer are oriented perpendicularly to the grain boundary to within a deviation of no more than 10°, as a result of a texturing of the substrate and/or at least one buffer layer disposed between the substrate and the high-temperature superconducting layer. This can be technologically implemented, for example, by growing on the HTS layer by way of graphoepitaxy.

Abstract: A gyrator for AC signals comprises a Hall effect material, means for coupling an alternating current (I1; I4) into the Hall effect material, means for permeating a Hall effect material with a magnetic field that is perpendicular to the plane or surface of the material, and means far converting a current (I3; I2), which was generated by the current I1 perpendicularly to the electric field generated by I1 in the Hall effect material, into an output voltage (U4; U1). A transformer is provided between at least one conductor loop (1a; 2a) made of a normal-conducting or semi-conducting material and at least one conductor loop (1; 2) made of the Hall effect material for coupling the current (I1; I4) into the Hall effect material and/or for converting the current (I3; I2) in the Hall effect material into the output voltage (U4; U1).

Abstract: A method for producing vectors containing a gene coding for an enzyme having reduced or deactivated feedback inhibition and to the use thereof for producing amino acids and nucleotide. Genes coding for feedback-inhibited enzymes are mutagenized in vitro, —ligated into vectors in a further step—the vectors are each transformed in a microorganism containing a metabolite sensor in a further step, which brings about the synthesis of a fluorescent protein at an increased metabolite concentration, —whereupon microorganisms exhibiting increased or maximum fluorescence are selected; and —the vectors that contain a gene coding for an enzyme having reduced or deactivated feedback inhibition are isolated from microorganisms having increased or maximum fluorescence.

Abstract: The invention relates to a method for producing a nanoporous layer on a substrate.

Abstract: Magnetoelectronic components comprise at least one oblong working structure made of a ferromagnetic material, along which magnetic domain walls can migrate, means for applying an electric current to this working structure, and at least one magnetic field sensor for the magnetic field generated by the working structure. The working structure is designed so that it is able to form domain walls, the transverse magnetization direction of which in the center has no preferred direction in the plane perpendicular to the migration direction thereof along the working structure, and/or can form massless domain walls. It was found that the kinetic energy of such moving domain walls vanishes. These walls are thus not subject to the Walker limit nor to intrinsic pinning. As a result, the components can read, store or process and finally output information more quickly. The invention also relates to a method for measuring the non-adiabatic spin transfer parameter ? of a ferromagnetic material.

Abstract: A molecule mixture comprising an amphipathic molecule of type A, which has an overall positive charge in the hydrophilic region, an amphipathic molecule of type B and a polyphenol C, the method for producing the molecule mixture, and the use thereof. The molecules of types A and B are present at a molecular ratio of A:B of 1(±0.2):1(±0.2) mol/mol. A method for producing the mixture and the use is also disclosed.

Abstract: Peptides that bind to amino-terminal truncated pEA?3-42, the free glutamic acid residue of which lies in position 3 or 11 in the form of cyclized pyroglutamate. Four oligopeptides were identified using mirror image phage display technology.

Abstract: The invention relates to the treatment of blood, blood products and organs for the removal and/or detoxification of amyloid-beta oligomers.

Abstract: A method is disclosed for desynchronizing neuronal brain activity of a patient in which the brain activity involves a neuron population firing in a synchronized manner. The method includes measuring a pathological frequency g of the neuronal brain activity of the patient, where the pathological frequency g relates to a pathological disorder of the patient. The method further includes calculating a stimuli frequency f based on the measured pathological frequency g, where the stimuli frequency f is calculated as being equal to the measured pathological frequency g×n/m, where n is 1, 2 or 3 and m is 1, 2 or 3, and controlling an electrode to generate stimuli in sequence with the stimuli succeeding each other at the stimuli frequency f, where the stimuli stimulate the neuron population of the patient.

Abstract: A device for applying a constant magnetic field to a volume of interest (VOI) has been developed. At least one magnetic field source and a permeable yoke, which guides the magnetic flux generated by this magnetic field source into the volume of interest (VOI). The yoke is guided through at least one closed conductor loop, which can be switched to the superconducting state so that, in the superconducting state of the conductor loop, a change in the flux through the yoke effects a current counteracting this change along the conductor loop. It has been identified that, in this way, the stabilizer for the magnetic field can be spaced so far apart from the volume of interest (VOI) that the field distribution in this volume is virtually no longer influenced. At the same time, the quality of the stabilization is also improved, since the conductor loop is no longer exposed to the entire magnetic field prevailing in the volume of interest (VOI).

Abstract: A hot wire device and method for depositing semiconductor material onto a substrate in a deposition chamber in which the ends of at least two filaments are clamped into a filament holder and heated by supplying current, wherein a voltage for generating an electrical current is applied in temporal succession to filaments made of differing materials so that a number of differing semiconductors corresponding to the number of consecutively heated filament materials can be consecutively deposited onto the substrate without opening the chamber.

Abstract: The present invention relates to novel tau protein aggregate-binding peptides, homologs, fragments, parts and polymers thereof and to the use thereof.

Abstract: The invention relates to a device for the stimulation of thermal receptors in the skin of a patient by means of thermal stimuli. The device comprises a plurality of noninvasive stimulation units for irradiating the skin of the patient with electromagnetic radiation, wherein thermal stimuli are produced by absorption of the electromagnetic radiation in the skin of the patient and the wavelength range of the electromagnetic radiation emitted by the stimulation units can be adjusted. The device also comprises a control unit for controlling the stimulation units.