Abstract: A method for manufacturing a nitride-based semiconductor device includes: preparing a substrate; forming a buffer layer on the substrate, the buffer layer preventing dislocation with the substrate; forming a spacer on the buffer layer; forming a barrier layer on the spacer, the barrier layer forming a hetero-structure with the spacer; forming a protecting layer on the barrier layer; and forming an HfO2 layer the protecting layer through RF sputtering.
Type:
Grant
Filed:
September 16, 2013
Date of Patent:
January 12, 2016
Assignee:
Seoul National University R&DB Foundation
Abstract: A composition of graphene-based nanomaterials and a method of preparing the composition are provided. A carbon-based precursor is dissolved in water to form a precursor suspension. The precursor suspension is placed onto a substrate, thereby forming a precursor assembly. The precursor assembly is annealed, thereby forming the graphene-based nanomaterials. The graphene-based nanomaterials are crystallographically ordered at least in part and configured to form a plurality of diffraction rings when probed by an incident electron beam. In one aspect, the graphene-based nanomaterials are semiconducting. In one aspect, a method of engineering an energy bandgap of graphene monoxide generally includes providing at least one atomic layer of graphene monoxide having a first energy bandgap, and applying a substantially planar strain is applied to the graphene monoxide, thereby tuning the first energy band gap to a second energy bandgap.
Type:
Grant
Filed:
June 12, 2013
Date of Patent:
January 12, 2016
Assignee:
UWM Research Foundation, Inc.
Inventors:
Junhong Chen, Marija Gajdardziska-Josifovska, Carol Hirschmugl, Eric Mattson, Haihui Pu, Michael Weinert
Abstract: Hardening of an integrated circuit such as a GPU processor to soft errors caused by particle strikes is applied selectively to the set of devices according to the magnitude of error resulting from this soft error for the particular device. This approach differs from approaches that protect all devices, all devices likely to produce an output error, or all devices that are vulnerable.
Type:
Grant
Filed:
February 14, 2014
Date of Patent:
January 12, 2016
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
David John Palframan, Nam Sung Kim, Mikko Lipasti
Abstract: The disclosure relates to a method for manufacturing a photoaligning integrated large area metallic stamp, which includes the following steps: making a unit device PLC mold pattern, and molding a unit PLC device pattern through a multistep imprinting method using the PLC mold pattern; heat treating the unit PLC device pattern to minimize scattering loss due to surface roughness; making a groove pattern for supporting an optical fiber; making an integrated PDMS mold for a unit device by aligning the unit PLC device pattern and the groove pattern; and repeatedly replicating the integrated PDMS mold for a unit device to make a large area PDMS pattern, and making a large area stamp through electroforming using the large area PDMS pattern.
Type:
Grant
Filed:
February 22, 2011
Date of Patent:
January 12, 2016
Assignee:
Pusan National University Industry-University Cooperation Foundation
Inventors:
Myung Yung Jeong, Seung Hun Oh, Jin Hwa Ryu, Sang Uk Cho, Tae Ho Lee
Abstract: High electron mobility transistors (HEMTs) having improved I-V characteristics and reliability are provided. According to one embodiment, a selective implantation is performed to form a damage region in a gate-to-drain region of, for example, an I?A?N/GaN HEMT. The selective implantation can be performed by irradiating some or all of a gate-to-drain region of an InAlN/GaN HEMT on a substrate with protons or other ions such as Ge ions, He ions, N ions, or O ions. The damage region can extend in a region below a 2DEG interface of the HEMT.
Type:
Grant
Filed:
September 11, 2013
Date of Patent:
January 12, 2016
Assignee:
University of Florida Research Foundation, Incorporated
Inventors:
Fan Ren, Stephen John Pearton, Jihyun Kim
Abstract: This document provides methods and materials for treating cancers including renal cancer (e.g., renal cell carcinoma) as well as ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancers and melanoma. For example, methods and material for using one or more inhibitors of an SCD1 polypeptide to treat renal cell carcinoma (e.g., clear cell renal cell carcinoma (ccRCC)) or to increase the efficacy of a renal cell carcinoma treatment are provided. In addition, this document provides methods and materials for using elevated SCD1 expression levels in diseased tissues as an indication that an SCD1 inhibitor can be used as an appropriate therapeutic to ameliorate the disease.
Type:
Grant
Filed:
March 7, 2013
Date of Patent:
January 12, 2016
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
John A. Copland, III, Laura Ann Marlow, Christina Von Roemeling
Abstract: Systems, apparatus and methods for collecting, storing, processing, reconstructing, and interpreting raw scan data from a medical diagnostic imaging scan. Raw data after a scan such as a Computed Tomography (CT) scan is sent to a raw scan database system and image reconstruction system, where image volumes are reconstructed using software from the software bank and sent to a data management system. Raw scan data generated once by a scanner is continuously used at later times to reconstruct images of the patient without having to perform additional patient scans.
Type:
Grant
Filed:
March 12, 2013
Date of Patent:
January 12, 2016
Assignees:
University of Central Florida Research Foundation, Inc., iTomography Corporation
Inventors:
Michael Frenkel, Alexander Katsevich, Igor Frenkel
Abstract: Disclosed is an apparatus and a method for controlling a user interface having a touch screen which includes an input and output unit having a touch screen, a camera which is installed to be separated from the input and output unit, and obtains at least one of an image data corresponding to a space within a critical distance from a front of the touch screen, and a controller which verifies an expected touch position of an object when a movement of the object is detected in the space as a result of an analysis of the image data, and controls the input and output unit to enlarge and output an area corresponding to the expected touch position.
Type:
Grant
Filed:
October 22, 2013
Date of Patent:
January 12, 2016
Assignees:
Hyundai Motor Company, SNU R&DB Foundation
Inventors:
Sang Eun Jin, Hyun-Woo Bang, Kee Hong Youn, Sung Min Cho, Jun Bong Song, Kyung Won Yun, Dong Youb Baek, Byung Joo Lee, Jae Hyuck Bae, Jung Man Chung
Abstract: In one embodiment, a system and a method involve receiving a raw signal collected by a sensor that pertains to a temporal trend, creating a reference signal of a known amplitude and frequency, adding the reference signal to the raw signal to form a modulated signal, decomposing the modulated signal to obtain a decomposed signal, and conducting time-frequency analysis on the decomposed signal to detect abnormal patterns.
Type:
Grant
Filed:
May 23, 2012
Date of Patent:
January 12, 2016
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: The present invention provides for enhancing engraftment by co-infusing at least two partially HLA matched umbilical cord blood (“UCB”) units. The invention further provides for positive C3a mediated priming on responsiveness to doses of SDF-1 and C3a induced incorporation of CXCR4 in membranes in HSC and progenitors. The invention further provides for enhancing the homing of UCB HSC and progenitors via the SDF-1/CXCR4 pathway and that C3a and LL-37 are useful for this method. It is also disclosed herein that fragments of C3a (e.g., des-Arg) are effective in the methods of the invention, including enhancing homing of HSPCs to BM. The invention further encompasses the disclosure herein of NFAT1 regulation post-transcriptionally by both mir-184 and IFN-?. The present invention further provides for measuring and using differences between UCB and adult CD4+/45RA+ T-cells as a means of defining strategies to enhance optimal allogeneic stem cell transplantation outcomes.
Type:
Grant
Filed:
February 27, 2013
Date of Patent:
January 12, 2016
Assignee:
University of Virginia Patent Foundation
Inventors:
Mary J. Laughlin, Mariusz Z. Ratajczak, Claudio Brunstein
Abstract: Composite materials are provided that include one or more CNT yarns embedded in a matrix material. The composite materials may be transparent. Methods for making the composite materials are also provided. The composite materials may be made by arranging at least one CNT yarn into a desired pattern and embedding the at least one CNT yarn into a matrix material.
Type:
Grant
Filed:
October 12, 2011
Date of Patent:
January 12, 2016
Assignee:
Florida State University Research Foundation, Inc.
Inventors:
Mei Zhang, Hang Zhang, Ben Wang, Richard Liang, Chuck Zhang
Abstract: A loaded wheel tester for testing asphalt mixtures comprises a loaded wheel tester having additional means for attachment to specimens under test to provide a measurement of tensile strain and for attachment between a frame of the loaded wheel tester and the loaded wheel to determine position of the loaded wheel over time. Output results demonstrate that viscoelastic and fatigue properties of asphalt mixtures are obtained in equivalent or improved format using a modified loaded wheel tester when compared with known pavement test apparatus and methods.
Type:
Grant
Filed:
March 29, 2012
Date of Patent:
January 12, 2016
Assignee:
University of Tennessee Research Foundation
Abstract: Cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex are disclosed. Also disclosed is the 3-D structure of the hRI.RNase 1 complex and methods for designing and using the RNase 1 variants.
Type:
Grant
Filed:
October 4, 2013
Date of Patent:
January 12, 2016
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Ronald T. Raines, George N. Phillips, Jr., R. Jeremy Johnson, Jason G. McCoy
Abstract: The present invention includes a composition for sterilizing a bioscaffold, comprising slightly acidic electrolyzed water (SAEW) as an active ingredient, and a method for sterilizing a bioscaffold using the same. The slightly acidic electrolyzed water according to the present invention has excellent effects on the sterilization of bioscaffolds and the removal of immunogenic antigens and a little effect on extracellular matrix, such as glycosaminoglycans or collagen. Moreover, the scaffold sterilized with the slightly acidic electrolyzed water has excellent cell attachment and has no toxicity, and thus the slightly acidic electrolyzed water can be effectively used for the sterilization of bioscaffolds.
Type:
Grant
Filed:
October 2, 2013
Date of Patent:
January 12, 2016
Assignee:
KNU University-Industry Cooperation Foundation
Inventors:
Heung Myong Woo, Kyung Mee Park, Kamal El Din Hany Hussein
Abstract: The present invention relates to a biodegradable suture-type cell delivery system, a preparation method thereof and a biodegradable suture comprising the same. The biodegradable suture-type cell delivery system has improved cell compatibility as a result of depositing a hydrophilic functional group-containing compound on the surface of a biodegradable suture yarn made of a biodegradable polymer, a portion of which has partially a bulky structure beneficial for the proliferation of cells or living tissue, so as to hydrophilically modify the surface, and then bonding a cell compatible material to the surface, and also functions as a cell culture scaffold, because the bulky structure is beneficial for the proliferation of cells. Accordingly, the biodegradable suture-type cell delivery system can improve the rate of engraftment of stem cells in vivo.
Type:
Grant
Filed:
November 18, 2009
Date of Patent:
January 12, 2016
Assignee:
Catholic University Industry Academic Cooperation Foundation
Inventors:
Heung Jae Chun, Su Jung You, Ki Dong Yoo, Kyu Nam Park, Gue Tae Chae, Seok Whan Moon, Han Joon Kim, Jung Hee Wee
Abstract: The invention provides methods of producing vaccines directed against microorganisms, with the methods comprising culturing, harvesting and/or suspending the microorganism in the presence of a radiation-protective composition and irradiating the bacteria or viruses with a dose of radiation sufficient to render the microorganism replication-deficient and/or non-infective. The radiation-protective compositions used in the methods of the present invention comprise at least one nucleoside, at least one antioxidant and at least one small peptide. The invention also provides methods of rendering bacteria in culture resistant to ionizing radiation (IR), with these methods comprising culturing the bacteria in the presence of a radiation-protective composition.
Type:
Grant
Filed:
April 29, 2011
Date of Patent:
January 12, 2016
Assignee:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
Abstract: Disclosed herein are methods of diagnosing, preventing and treating Alzheimer's disease based on the use of an inhibitor for the binding of amyloid-? (A?) to Fc?RIIb, and a method of screening the inhibitor. The inhibitor is selected from the group consisting of an Fc?RIIb protein or a variant thereof, an Fc?RIIb extracellular domain, an anti-Fc?RIIb antibody, an Fc?RIIb-specific peptide and an Fc?RIIb-specific siRNA. The inhibitor reduces the toxic signaling and intracellular translocation of A? and the neurotoxicity, neuronal cell death and memory impairment mediated by A? by inhibiting the binding between A? and Fc?RIIb. Thus, the inhibitor is useful in the diagnosis, prevention and treatment of Alzheimer's disease.
Type:
Grant
Filed:
January 19, 2012
Date of Patent:
January 12, 2016
Assignee:
Seoul National University Industry Foundation
Abstract: A method of operating an electronic device for image interpolation is provided. The method includes estimating a direction of pixels using a plurality of filters respectively corresponding to a plurality of angles, correcting the direction of the pixels using a direction of neighboring pixels, determining whether the direction estimation has an error according to a direction distribution of the neighboring pixels, and when the direction estimation is determined to have error, correcting the error in the direction estimation.
Type:
Grant
Filed:
June 28, 2013
Date of Patent:
January 12, 2016
Assignees:
Samsung Electronics Co., Ltd., Chung-Ang University Industry-Academy Cooperation Foundation
Inventors:
Min-Kyu Park, Joon-Ki Paik, Won-Seok Kang, Han-Sae Song, Young-Sam Yu, Jae-Hwan Jeon, Young-Kwon Yoon, Yong-Gu Lee
Abstract: This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, a target volume of activation (VOA) can be received, a test VOA can be simulated, and at least one of a target electrode location or parameter can be provide using a relationship between the target VOA and the test VOA.
Type:
Grant
Filed:
October 9, 2008
Date of Patent:
January 12, 2016
Assignee:
The Cleveland Clinic Foundation
Inventors:
Cameron C. McIntyre, Christopher R. Butson, John D. Hall, Jaimie M. Henderson
Abstract: The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detection phase. The ligation phase utilizes a ligation detection reaction between one oligonucleotide probe, which has a target sequence-specific portion and an addressable array-specific portion, and a second oligonucleotide probe, having a target sequence-specific portion and a detectable label. After the ligation phase, the capture phase is carried out by hybridizing the ligated oligonucleotide probes to a solid support with an array of immobilized capture oligonucleotides at least some of which are complementary to the addressable array-specific portion. Following completion of the capture phase, a detection phase is carried out to detect the labels of ligated oligonucleotide probes hybridized to the solid support.
Type:
Grant
Filed:
December 9, 2013
Date of Patent:
January 12, 2016
Assignee:
Cornell Research Foundation, Inc.
Inventors:
Francis Barany, George Barany, Robert P. Hammer, Maria Kempe, Herman Blok, Monib Zirvi