Abstract: The invention relates to nanomaterials and assemblies including, a micrometer-scale spherical aggregate comprising: a plurality of one-dimensional nanostructures comprising titanium and oxygen, wherein the one-dimensional nanostructures radiate from a hollow central core thereby forming a spherical aggregate.
Type:
Application
Filed:
April 29, 2013
Publication date:
August 27, 2015
Applicant:
The Research Foundation for The State University of New York
Abstract: The present invention relates to monoclonal antibodies which specifically recognize human liver-carboxylesterase 1, hybridoma cell lines which produce monoclonal antibodies, and uses thereof. The invention can be used for the objective analysis of the expression amount of human liver-carboxylesterase 1 in tissues and blood, and the like, by being specifically bound to the human liver-carboxylesterase 1. Therefore, liver cancer can be conveniently and quickly diagnosed from urine or blood.
Type:
Grant
Filed:
April 17, 2012
Date of Patent:
August 25, 2015
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University
Abstract: An image processing method and an image processing apparatus for removing noise from an image are disclosed. A provided image processing method includes: dividing an input image into a luminance signal and a chrominance signal; removing noise from the luminance signal; restoring luminance signal present in the noise removed from the luminance signal; removing noise from the chrominance signal; and combining the luminance signal and the chrominance signal from which the noises are removed. Accordingly, an image of which an edge component is well preserved and a degree of color noise is low is generated not only in a general environment but also in a low light level and high sensitivity environment having a large amount of noise.
Type:
Grant
Filed:
August 22, 2012
Date of Patent:
August 25, 2015
Assignees:
Samsung Electronics Co., Ltd., Industry-University Cooperation Foundation Sogang University
Inventors:
Soon-geun Jang, Rae-hong Park, Young-il Pyo
Abstract: Devices and processes for performing magnetic resonance imaging of the anatomy of a patient during radiation therapy to measure and control the radiation dose delivered to the patient.
Type:
Grant
Filed:
March 1, 2013
Date of Patent:
August 25, 2015
Assignee:
University of Florida Research Foundation, Inc.
Abstract: An apparatus and a method for tracing a parking-lot is provided that includes a controller configured to recognize at least one parking-lot from a previous image frame which photographed a surrounding of a vehicle and extract a template according to a type of a parking-lot line of the recognized parking-lot. In addition, the controller is configured to generate a template transformed based on a position information of the parking-lot and calculate similarity by comparing a template generated from a previous image frame with a parking-lot line recognized from a current image frame. A position of a parking-lot is determined according to the calculated similarity and the controller is configured to correct the template based on an information of a parking-lot line extracted from the determined position.
Type:
Grant
Filed:
October 1, 2013
Date of Patent:
August 25, 2015
Assignees:
Hyundai Motor Company, Kia Motors Corporation, Industry-University Cooperation Foundation Hanyang University
Inventors:
Jae Seob Choi, Seong Sook Ryu, Dae Joong Yoon, Eu Gene Chang, Ho Gi Jung, Jae Kyu Suhr
Abstract: A mechanochemical oxidation process that allows relatively benign oxidizers to be used for the production of at least partially oxidized graphite, and a method of preparing a carbon fiber using oxidized graphite and a fiber component. Partially oxidized graphite is fully dispersible in water and can be used to prepare thin films with conductivities rivaling pure graphite. This offers the potential for improved electronic displays, solar cells, and lithium ion batteries. A carbon nanotube and a method of making the same is also provided.
Type:
Grant
Filed:
October 28, 2011
Date of Patent:
August 25, 2015
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A composite light source includes a substrate having a top surface, and a first vertical light source formed in the substrate. The first light source includes least a lower mirror, a first active region above the lower mirror, wherein the first active region has a thickness sufficient when electrically pumped to emit predominantly a spontaneous vertical emission from the first active region towards the top surface having an angular range of at least (?) 30°. A second light source is formed in the substrate above the first active region including a second active region. The spontaneous vertical emission is at a first wavelength ?1 that optically drives said second active region to provide an emission at a second wavelength ?2, wherein ?2>?1.
Type:
Grant
Filed:
May 20, 2014
Date of Patent:
August 25, 2015
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: An apparatus for reconstructing 3D images by using magnetic resonance imaging (MRI) includes an image acquiring unit configured to acquire a plurality of MR images about a region of interest of an object at different angles, respectively; and an image reconstructing unit configured to reconstruct the 3D image by using the plurality of MR images, wherein the plurality of MR images include information of a slice direction about the region of interest, which is changed depending on the different angles. According to the invention, since the 3D image is reconstructed by using the MR images acquired at different angles, the 3D image may have a better SNR than the method for reconstructing 3D images of the related art.
Type:
Grant
Filed:
April 27, 2012
Date of Patent:
August 25, 2015
Assignee:
Industry Academic Cooperation Foundation, Yonsei University
Inventors:
Dong-Hyun Kim, Min-Oh Kim, Sang-Young Zho
Abstract: Disclosed herein are point mutations in the LMNA gene that cause HGPS. These mutations activate a cryptic splice site within the LMNA gene, which leads to deletion of part of exon 11 and generation of a mutant Lamin A protein product that is 50 amino acids shorter than the normal protein. In addition to the novel Lamin A variant protein and nucleic acids encoding this variant, methods of using these molecules in detecting biological conditions associated with a LMNA mutation in a subject (e.g., HGPS, arteriosclerosis, and other age-related diseases), methods of treating such conditions, methods of selecting treatments, methods of screening for compounds that influence Lamin A activity, and methods of influencing the expression of LMNA or LMNA variants are also described.
Type:
Grant
Filed:
September 12, 2013
Date of Patent:
August 25, 2015
Assignees:
The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services, Research Foundation for Mental Hygiene, Inc., The Progeria Research Foundation, Inc.
Inventors:
B. Maria H. Eriksson, Francis S. Collins, Leslie B. Gordon, William Ted Brown
Abstract: Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER/neu oncogene, GP2, with the effect of inducing and maintaining protective or therapeutic immunity against breast cancer in a patient in clinical remission, including patients having low to intermediate levels of HER2/neu expression. The methods comprise administering to the patient an effective amount of a vaccine composition comprising a pharmaceutically acceptable carrier, an adjuvant such as GM-CSF, and the GP2 peptide. The methods may further comprise administering a periodic booster vaccine dose as needed due to declining GP2-specific T cell immunity. Also provided are vaccine compositions for use in the methods.
Type:
Grant
Filed:
December 9, 2009
Date of Patent:
August 25, 2015
Assignee:
The Henry M. Jackson Foundation for the Advancement of Miltary Medicine, Inc.
Abstract: The present invention provides peptides (including analogs and derivatives thereof) corresponding to residues 96-110 and 35-47 of ras-p21, which peptides have attached thereto a membrane-penetrating leader sequence. The subject peptides, analogs and derivatives thereof are useful in treatment of cancers and have been shown to induce phenotypic reversion of pancreatic cancer cells to non-cancerous cells. Pharmaceutical compositions comprising one or more subject peptides are also provided by the present invention. The present invention further provides replication incompetent Adenovirus (AdV) vectors comprising a promoter sequence and a nucleotide sequence encoding a subject peptide. Methods of treating cancer by administering one or more subject peptides, pharmaceutical compositions, and/or AdV vectors are also provided.
Type:
Grant
Filed:
November 15, 2012
Date of Patent:
August 25, 2015
Assignee:
The Research Foundation of State University of New York
Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.
Type:
Grant
Filed:
April 21, 2014
Date of Patent:
August 25, 2015
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
John C. Burnett, Jr., Candace Y. W. Lee
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one porous material connected to a high voltage source, in which the porous material is discrete from a flow of solvent.
Type:
Grant
Filed:
December 5, 2014
Date of Patent:
August 25, 2015
Assignee:
Purdue Research Foundation
Inventors:
Zheng Ouyang, He Wang, Nicholas E. Manicke, Robert Graham Cooks, Qian Yang, Jiangjiang Liu
Abstract: A method of processing an audio signal is disclosed. The present invention includes a method for processing an audio signal, comprising: receiving, by an audio processing apparatus, the spectral data including a current block, and substitution type information indicating whether to apply a shape prediction scheme to a current block; when the substitution type information indicates that the shape prediction scheme is applied to the current block, receiving lag information indicating an interval between spectral coefficients of the current block and the predictive shape vector of a current frame or a previous frame; obtaining spectral coefficients by substituting for spectral hole included in the current block using the predictive shape vector.
Type:
Grant
Filed:
November 2, 2010
Date of Patent:
August 25, 2015
Assignees:
LG Electronics Inc., Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Hyen-O Oh, Chang Heon Lee, Hong Goo Kang
Abstract: An apparatus for treating cardiovascular diseases includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between the end portions for positioning in a blood vessel. The proximal end portion of the expandable support member includes a plurality of wing members that extend from the main body portion. Each of the wing members is for engaging at least a portion of an antrum of a cardiac chamber surrounding the blood vessel. At least a portion of the expandable support member is treated with at least one therapeutic agent for eluting into the blood vessel, the cardiac chamber, and/or cardiac tissue. The expandable support member is made of wire-mesh, and at least a portion of the expandable support member may be made of a bioabsorbable material.
Abstract: A device and a method are provided for measuring the yield stress of a fluid. The device includes a container for receiving the fluid therein and an auger having a shaft extending along an axis and a helical flange extending radially about the shaft. The auger is movable in the fluid between a first position and a second position. A sensor is operatively connected to the auger. The sensor measures a force on the auger as the auger moves from the first position to the second position. A linkage is interconnected to the sensor. The linkage translates motion to the auger.
Type:
Grant
Filed:
October 7, 2011
Date of Patent:
August 25, 2015
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Joseph R. Samaniuk, Daniel J. Klingenberg, Charles T. Scott, Thatcher W. Root
Abstract: Disclosed are a gene carrier in which polyethyleneglycol is conjugated with polyethyleneimine and a method for the synthesis thereof. The gene carrier is useful in transferring DNA, siRNA and negatively charged peptides.
Abstract: Surface-modifying layers, including neutral layers for vertical domain-forming block copolymers of styrene and methyl methacrylate are provided. Also provided are self-assembled block copolymer structures incorporating the surface modifying layers, methods of fabricating such structures and methods of using the structures in BCP lithography applications. The surface-modifying layers comprise a crosslinked copolymer film, wherein the crosslinked copolymers are random copolymers polymerized from styrene monomers and/or (meth)acrylate monomers and crosslinkable epoxy group-functionalized monomers. The crosslinked copolymer films are characterized by a high content of the crosslinkable epoxy group-functionalized monomer.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
August 25, 2015
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Padma Gopalan, Eungnak Han, Myungwoong Kim
Abstract: A device and method for marking a treatment isocenter on a patient's body. One embodiment includes a base including alignment indicia, a marker disposed over the base and positioned relative to the indicia for marking the isocenter on the patient's body and an actuator for actuating the marker and causing a mark indicating the isocenter to be made on the patient's body. The actuator can include a button and a spring coupled to the marker. Compressing the actuator causes the marker to travel through an ink well prior to piercing the patient's skin.
Type:
Grant
Filed:
February 24, 2012
Date of Patent:
August 25, 2015
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Robert D. Ahmann, James A. Starr, Broc T. Giffey