Patents Assigned to Foundation
  • NOVEL PRODRUGS FOR SELECTIVE ANTICANCER THERAPY
    Publication number: 20150224208
    Abstract: The present invention provides a compound having the structure: wherein X is a therapeutic agent containing at least one amine nitogen and the amine nitrogen on the therapeutic agent covalently bonds directly to carbon ?; Z is CH3 or CF3; R1 is —H, —NR2R3, —NH—C(?O)—R4, —NH—C(?O)—OR4, —CH2—C(?O)—NR5R6, —OR7, —CO2R7, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, or heteroaryl, wherein R2, R3, R4, R5, R6 and R7 are each, independently, —H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, heteroalkyl, cycloalkyl, heterocyclyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, an amino acid or an oligopeptide; wherein an amine of the amino acid or oligopeptide is substituted or unsubstituted; and n is an integer from 0 to 6; or a diastereomer, enantiomer or pharmaceutically acceptable salt of the compound.
    Type: Application
    Filed: September 18, 2013
    Publication date: August 13, 2015
    Applicant: The Research Foundation for The State University of New York
    Inventors: Nobuhide Ueki, Michael J. Hayman
  • COMPOSITIONS AND METHODS FOR DELIVERING AN AGENT TO A WOUND
    Publication number: 20150224236
    Abstract: The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).
    Type: Application
    Filed: February 10, 2015
    Publication date: August 13, 2015
    Applicant: University of Memphis Research Foundation
    Inventors: Warren O. Haggard, Scott P. Noel, Joel D. Bumgardner
  • FIELD EFFECT TRANSISTOR USING GRAPHENE
    Publication number: 20150228804
    Abstract: According to example embodiments, a field effect transistor includes a graphene channel layer on a substrate. The graphene channel layer defines a slit. A source electrode and a drain electrode are spaced apart from each other and arranged to apply voltages to the graphene channel layer. A gate insulation layer is between the graphene channel layer and a gate electrode.
    Type: Application
    Filed: April 22, 2015
    Publication date: August 13, 2015
    Applicant: Seoul National University R&DB Foundation
    Inventors: Jae-ho LEE, Seong-jun PARK, Kyung-eun BYUN, David SEO, Hyun-jae SONG, Hyung-cheol SHIN, Jae-hong LEE, Hyun-jong CHUNG, Jin-seong HEO
  • NMOS-OFFSET CANCELING CURRENT-LATCHED SENSE AMPLIFIER
    Publication number: 20150228322
    Abstract: A resistive memory sensing method includes sensing outputs of an offset-cancelling dual stage sensing circuit (OCDS-SC) by an NMOS offset-cancelling current latched sense amplifier circuit (NOC-CLSA). The NOC-CLSA is configured with a reduced input capacitance and a reduced offset voltage. Input transistors of the NOC-CLSA are coupled between latch circuitry and ground. A first phase output of the OCDS-SC is stored by the NOC-CLSA during a pre-charge step of the NOC-CLSA operation. A second phase output of the OCDS-SC is stored by the NOC-CLSA during an offset-cancelling step of the NOC-CLSA operation. By pipelining the OCDS-SC and NOC-CLSA, a sensing delay penalty of the OCDS-SC is overcome.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 13, 2015
    Applicants: Industry-Academic Cooperation Foundation, Yonsei University, QUALCOMM Incorporated
    Inventors: Seong-Ook JUNG, Taehui NA, Ji-su KIM, Jung Pill KIM, Seung Hyuk KANG
  • CATALYST CARRIER FOR PURIFICATION OF EXHAUST GAS, METHOD FOR PREPARING THE SAME, AND CATALYST FOR PURIFICATION OF EXHAUST GAS
    Publication number: 20150224491
    Abstract: A catalyst carrier for purification of exhaust gas, may include a substrate having a plurality of cell paths partitioned by a cell barrier rib and a ceramic coating layer positioned on the inside surface of the cell path, where the ceramic coating layer has a porous lamellar structure arranged in an exhaust gas flow direction, and a method for preparing the same.
    Type: Application
    Filed: September 12, 2014
    Publication date: August 13, 2015
    Applicants: Hyundai Motor Company, Kia Motors Corporation, Chung-Ang University Industry Academic Cooperation Foundation
    Inventors: Hyokyung LEE, Jin Woo CHOUNG, Jonghwi LEE, Byoung Soo KIM
  • Chimeric aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 9102757
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: August 11, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Method and device for controlled laminar flow patterning within a channel
    Patent number: 9103502
    Abstract: A device and method of laminar flow patterning of at least one sample fluid in a main channel in a microfluidic device are provided. A first input channel is provided in the microfluidic device. The first input channel has an output end communicating with the first end of the main channel and an input end communicating with a first input port. A buffer fluid is deposited in the main channel and the first input channel and a first sample fluid is deposited in the first input port. A first pressure is generated in response to the depositing of the first sample fluid in the first input port so as to cause laminar flow of the first sample fluid in the main channel.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: August 11, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Jay Warrick, Erwin Barthler
  • Wireless SAW sensors having integrated antennas
    Patent number: 9106205
    Abstract: A wireless surface acoustic wave sensor includes a piezoelectric substrate, a surface acoustic wave device formed on the substrate, and an antenna formed on the substrate. In some embodiments, the antenna is formed on the surface of the substrate using one or more of photolithography, thin film processing, thick film processing, plating, and printing.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: August 11, 2015
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Mark Gallagher, Donald C. Malocha
  • Methods and compositions for treating mammalian nerve tissue injuries
    Patent number: 9101655
    Abstract: To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury. Alternatively, the biomembrane fusion agent is delivered to the site of the injury through the blood supply after administration of the biomembrane fusion agent to the patient. The administration is preferably by parenteral administration including intravascular, intramuscular, subcutaneous, or intraperitoneal injection of an effective quantity of the biomembrane fusion agent so that an effective amount is delivered to the site of the nerve tissue injury.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: August 11, 2015
    Assignee: Purdue Research Foundation
    Inventors: Riyi Shi, Richard B. Borgens
  • System and method for managing sensor node in RFID/USN infrastructure and gateway system used therefor
    Patent number: 9107033
    Abstract: A sensor node management system in a Radio Frequency Identification/Ubiquitous Sensing Network (RFID/USN) infrastructure is provided, in which a sensor node has a local ID in a sensor network, a gateway receives, from the sensor node, node information including the local ID and an ID of a home gateway to which the sensor node initially belongs and registers the node information about the sensor node to a location information server, and the location information server registers and manages node information about sensor nodes within an area of the gateway. The location information server generates a global ID using the local ID and the ID of the home gateway, the global ID being recognized as an address of the sensor node by an Internet Protocol (IP) network.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: August 11, 2015
    Assignee: Korea University Research and Business Foundation
    Inventors: Sun-Shin An, Sang-Bin Lee, Sung-Jun Kim
  • GMR nanowire sensors
    Patent number: 9103654
    Abstract: A magnetic position sensor having at least one magnetic field sensor including a solidified layer of GMR nanowire carrier fluid formed on a substrate material. The solidified layer of carrier fluid has (i) discrete GMR nanowires each having a diameter of less than about 0.5 um and a length less than about 250 um; and (ii) a concentration of GMR nanowires in the dried layer between about 0.001 and about 10 percent by weight of the solution. The position sensor further includes a detection circuit capable of detecting a change in resistance of the magnetic field sensor.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 11, 2015
    Assignee: Louisiana Tech University Research Foundation, a division of Louisiana Tech University Foundation, Inc.
    Inventor: Bryan Cox
  • Microscopy visualization
    Patent number: 9104903
    Abstract: A method is described for correlating microscopy images from a number of modalities in a sub diffraction resolution environment. The method may include receiving a number of datasets that may represent microscopy captures from a number of different modalities. The microscopy captures may contain feature markers that may be used to register a number of data points contained in a dataset with data points from another dataset. Upon registering the data points of the datasets, a combined dataset may be produced and a visual image of the combined dataset may be provided.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: August 11, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Steven P. Callahan, Bryan W. Jones, Greg M. Jones, Erik Jorgensen, John Schreiner, Tolga Tasdizen, Shigeki Watanabe, Stan Kanarowski, Josh Cates
  • Single nucleotide polymorphisms associated with bull fertility
    Patent number: 9102985
    Abstract: Single nucleotide polymorphic sites of the bovine MAP1B, PPP1R11, and DDX4 genes are associated with improved bull fertility as measured by e.g. sire conception rates. Nucleic acid molecules, arrays, kits, methods of genotyping and marker-assisted bovine breeding methods based on these SNPs are disclosed.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 11, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Hasan Khatib
  • Pharmaceutical composition for inhibiting abnormal proliferation of cells
    Patent number: 9102942
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diseases related to abnormal proliferation of cells, comprising a cytoplasmic heat shock protein (Hsp)60 kDa inhibitor as an active ingredient, and to a screening method and a kit using the composition. According to the present invention, substances which inhibit expression of cytoplasmic Hsp 60 genes or inhibit activity of cytoplasmic Hsp 60 or inhibit binding between cytoplasmic Hsp 60 and IKK protein prevent interaction between cytoplasmic Hsp 60 and IKK complexes to make NF-?B path inactive, and thus induce apoptosis. Therefore, the substances can be valuably used in preventing or treating diseases related to abnormal proliferation of cells, such as cancer, inflammatory diseases or hyperproliferative vascular diseases.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: August 11, 2015
    Assignee: Ewha University—Industry Collaboration Foundation
    Inventors: Sang Won Kang, Soo Young Lee
  • Ferroelectric memory device and method for manufacturing same
    Patent number: 9105345
    Abstract: The present invention relates to a ferroelectric memory device having a multilevel polarization (MLP) state generated due to adjustment of a displacement current and to a method for manufacturing the ferroelectric memory device.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: August 11, 2015
    Assignee: Seoul National University R&DB Foundation
    Inventors: Tae Won Noh, Daesu Lee, Jong-Gul Yoon
  • Viscoelastic silicone rubber compositions
    Patent number: 9102799
    Abstract: This invention relates to viscoelastic silicone rubber compositions that are the products of the reaction of: (a) a silanol-terminated polyorganosiloxane base; (b) a boron-containing crosslinking agent; and (c) a siloxane bond-forming crosslinking agent. In a viscoelastic silicone rubber composition of the invention some of the crosslinks, the siloxane crosslinks, are permanent and others of the crosslinks, the boron-containing crosslinks, are temporary. Because a fraction of its crosslinks can come apart and then reform, a viscoelastic silicone rubber composition of the invention can relax stress in response to strain and thus adapt to new shapes. The composition has sufficient permanent crosslinks, however, to establish a permanent equilibrium shape to which the composition will eventually return when not subject to any imposed stress.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: August 11, 2015
    Assignee: University of Virginia Patent Foundation
    Inventor: Louis A. Bloomfield
  • Gas filled hollow fiber laser
    Patent number: 9106055
    Abstract: Apparatus, systems, and methods using an optically pumped gas filled hollow fiber laser can be implemented in a variety of applications. In various embodiments, operation of an optically pumped gas filled hollow fiber laser is based on population inversion in the gas. Additional apparatus, systems, and methods are disclosed.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: August 11, 2015
    Assignees: STC.UNM, Kansas State University Research Foundation
    Inventors: Wolfgang G. Rudolph, Amarin Ratanavis, Vasudevan Nampoothiri, Kristan L. Corwin, Andrew M. Jones, Brian R. Washburn, Rajesh Kadel, John M. Zavada
  • Method and apparatus for transmitting signaling information in digital broadcasting system
    Patent number: 9106261
    Abstract: A method and an apparatus for puncturing bits in parity bit groups in a digital broadcasting system are provided. In a method for transmitting signaling information in a digital broadcasting system, a received information bit stream is encoded and a parity bit is added. The parity bit is punctured such that parity bits of different patterns are formed between adjacent frames.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: August 11, 2015
    Assignees: Samsung Electronics Co., Ltd, Postech Academy-Industry Foundation
    Inventors: Hong-Sil Jeong, Kyung-Joong Kim, Seok-Ki Ahn, Kyeongcheol Yang, Hyun-Koo Yang, Sung-Ryul Yun
  • Image processing device, image processing method, recording medium, and program
    Patent number: 9105239
    Abstract: There is provided an image processing device including a movement section which scrolls a medical image on a screen, and a display control section which, in a case where the medical image is scrolled on the screen, controls a display section to display the medical image in a manner that an observation reference position of a diagnosis region of the medical image passes through a display reference position of a display region of the screen.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: August 11, 2015
    Assignees: Sony Corporation, Japanese Foundation For Cancer Research
    Inventors: Takeshi Ohashi, Jun Yokono, Takuya Narihira
  • Tunable plasmonic crystal
    Patent number: 9105791
    Abstract: A tunable plasmonic crystal comprises several periods in a two-dimensional electron or hole gas plasmonic medium that is both extremely subwavelength (˜?/100) and tunable through the application of voltages to metal electrodes. Tuning of the plasmonic crystal band edges can be realized in materials such as semiconductors and graphene to actively control the plasmonic crystal dispersion in the terahertz and infrared spectral regions. The tunable plasmonic crystal provides a useful degree of freedom for applications in slow light devices, voltage-tunable waveguides, filters, ultra-sensitive direct and heterodyne THz detectors, and THz oscillators.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: August 11, 2015
    Assignees: Sandia Corporation, The Research Foundation of the City University of New York
    Inventors: Gregory Conrad Dyer, Eric A. Shaner, John L. Reno, Gregory Aizin