Abstract: The present invention relates to methods for producing an oligonucleotide on a solid substrate surface and methods for using the same. Some aspects of the invention provide methods for selecting a single DNA molecule reproducibily with an atomic force microscope (AFM).
Type:
Grant
Filed:
November 16, 2009
Date of Patent:
March 10, 2015
Assignees:
Postech Foundation, Posco
Inventors:
Joon Won Park, Bong Jin Hong, Duk Hoe Kim
Abstract: Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an antigen. The invention also provides relate methods for amplifying vaccine immunity by administering to an individual an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an vaccine. The invention also provides related methods of inhibiting tumor growth and metastasis by administering to an individual with cancer an angiotensin II receptor blocker or a compound of Formula (I) in conjunction with an anti-tumor preparation. In addition, related compositions comprising an ARB or a compound of Formula (I) and an antigen, vaccine, or anti-tumor preparation are provided.
Type:
Grant
Filed:
March 3, 2014
Date of Patent:
March 10, 2015
Assignee:
Colorado State University Research Foundation
Inventors:
Steven W. Dow, Daniel P. Regan, Amanda M. Guth, Leah Mitchell
Abstract: An improved self-adjusting automatic slack adjuster for reducing slack in the brake of a vehicle is provided, in which an easily accessible external operating feature permits the automatic slack adjuster's one-way clutch assembly to be readily disengaged to allow smooth release and retraction of the brake shoes of a vehicle brake without damage to the one-way teeth of the clutch assembly. When the external feature is operated in a brake release direction, the motion of the feature is translated into a motion which axially displaces an output part of the one-way clutch away from an input part of the clutch a distance sufficient to disengage the parts' one-way teeth, thereby disengaging the one-way clutch to permit brake shoe retraction without resistance from the one-way clutch.
Type:
Grant
Filed:
January 30, 2014
Date of Patent:
March 10, 2015
Assignee:
Bendix Spicer Foundation Brake LLC
Inventors:
Mark Kromer, John Louis, Zoltan Tormasi
Abstract: In a mobile communication system and a broadcasting system, an Advanced Base Station (ABS) periodically broadcasts a buffering data packet of broadcast buffering content in providing a Mobile Internet Protocol TeleVision (Mobile IPTV) service. The broadcast buffering content represents content in which a buffering data packet corresponding to a predetermined buffering capacity is periodically broadcasted, and the buffering data packet represents a data packet that is transmitted to be buffered in advance before the broadcast buffering content is actually provided to Advanced Mobile Stations (AMSs).
Type:
Grant
Filed:
May 10, 2011
Date of Patent:
March 10, 2015
Assignee:
Industry-University Cooperation Foundation Korea Aerospace University
Abstract: Embodiments of the present disclosure include structures, photocatalytic structures, and photoelectrochemical structures, methods of making these structures, methods of making photocatalysis, methods of splitting H2O, methods of splitting CO2, and the like.
Type:
Grant
Filed:
November 10, 2009
Date of Patent:
March 10, 2015
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: A compound or its pharmaceutically acceptable salt, as well as a pharmaceutical, composition containing that compound or salt dissolved or dispersed in a pharmaceutically acceptable carrier, and a method of using that compound or salt in an antibacterial treatment. A contemplated compound corresponds in structure to structural Formula I or a pharmaceutically acceptable salt of that compound, wherein V is O or NR9, Y is halogen, OR10, C1-C4 hydrocarbyl or NHR10, Z is NR2—X—R1 or CH2—R8, n is 1-6, X is H, S(O)2, C(O), C(O)NR7, C(NH)NR7 or C(O)O, and R1, R2, R7, R8, R9 and R10 are defined within.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
March 10, 2015
Assignee:
The Penn State Research Foundation
Inventors:
Kenneth Charles Keiler, John Nandwa Alumasa
Abstract: Provided is a human antibody having a neutralization activity against a human influenza virus. More specifically, provided is a human antibody which recognizes a highly conserved region in a human influenza A virus subtype H3N2 or a human influenza B virus and has a neutralization activity against the virus. The human antibody is a human anti-human influenza virus antibody, which has a neutralization activity against a human influenza A virus subtype H3N2 and binds to a hemagglutinin HA1 region of the human influenza A virus subtype H3N2, or which has a neutralization activity against a human influenza B virus, and includes, as a base sequence of a DNA encoding a variable region of the antibody, a sequence set forth in any one of SEQ ID NOS: 5 to 12.
Type:
Grant
Filed:
December 24, 2009
Date of Patent:
March 10, 2015
Assignees:
Osaka University, The Research Foundation for Microbial Diseases of Osaka University
Abstract: Disclosed is a portable terminal, a battery pack and an apparatus for controlling a battery unit. The battery pack includes k battery units, wherein k is an integer of 2 or more; a power supply control unit that conducts control operation such that at least one of the k battery units supplies a power to a load by a time period, and other battery units except for the at least one are in an idle state in a whole or part of the time period.
Type:
Grant
Filed:
December 8, 2011
Date of Patent:
March 10, 2015
Assignee:
Foundation of Soongsil University-Industry Cooperation
Inventors:
Seongsoo Lee, Yongju Jang, Sangho Kim, JaeHo Lim
Abstract: A contact type tactile feedback apparatus and operational method of the contact type tactile feedback apparatus is provided. The contact type tactile feedback apparatus may enable an object to be in close contact with a power feedback portion to transfer a power sensed by a sensor, using a fixing portion, thereby enabling the object to recognize the power, intuitively.
Type:
Grant
Filed:
February 19, 2013
Date of Patent:
March 10, 2015
Assignees:
Samsung Electronics Co., Ltd., Industry-University Cooperation Foundation Sogang University
Abstract: The invention provides isolated fungal endophytes and synthetic combinations thereof with host grass plants. Methods for inoculating grass plant with the endophytes, for propagating the grass-endophyte combinations, and for producing feeds and biofuels from grass-endophyte combinations are also provided.
Abstract: Disclosed is an adsorptive ball for recovering precious metals and resources, a method for manufacturing the adsorptive bale, a flow through-continuous deionization (FT-CDI) module capable of recovering precious metals by using the adsorptive ball, and a flow through-continuous deionization (FT-CDI) apparatus having the flow through-continuous deionization (FT-CDI) installed thereat.
Type:
Grant
Filed:
October 15, 2012
Date of Patent:
March 10, 2015
Assignees:
The Industry & Academic Cooperation in Chungnam National University, Pusan National University Industry-University Cooperation Foundation
Inventors:
Teak Sung Hwang, Won Ho Jung, Noh-Seok Kwak, Sung-gyu Park, Jin Sun Koo, Hui-Man Park, Chi Won Hwang, Chang-Sik Ha
Abstract: Provided is a channel state information (CSI) sharing method and apparatus in a Multiple User Multiple Input Multiple Output (MU-MIMO) environment. Each node may use network-coding to reduce overhead necessary for sharing CSI between all nodes in the MU-MIMO environment. A transmitter may dynamically select, based on the CSI between receivers, a path used for transmitting data to each receiver and a receiver to be used as a relay based on the global CSI. A decoding performance may be improved based on the CSI between the transmitter and the receivers.
Type:
Grant
Filed:
December 30, 2010
Date of Patent:
March 10, 2015
Assignees:
Samsung Electronics Co., Ltd., Purdue Research Foundation
Inventors:
Bruno Clerckx, Jun Il Choi, Taejoon Kim, Obadamilola Aluko, David J. Love
Abstract: A system and method are provided for mounting, removing and retaining brake pads in disc brakes, such as air-operated disc brakes utilized on commercial vehicles, in a manner which does not require the use of separate brake pad retaining devices while providing positive retention of the brake pad. A preferred embodiment includes a brake caliper mount having brake pad abutment surfaces having radially-oriented and lateral grooves which permit a brake pad with corresponding projections on is lateral sides to be inserted through an opening of the brake caliper into the radially-oriented grooves until the backing plate projections are aligned with the lateral groove, and advancing the brake actuator behind the brake pad to place the brake pad in an operating position in which the actuator prevents the brake pad from realigning with the radially-oriented grooves until the actuator is retracted to permit brake pad extraction.
Type:
Grant
Filed:
August 17, 2012
Date of Patent:
March 10, 2015
Assignee:
Bendix Spicer Foundation Brake LLC
Inventors:
Ronald S. Plantan, Harish Radhakrishnan, Dennis A. Wolf, Richard L. Lantz, Will E. Roberts, Steven C. Bell
Abstract: A roller bearing having a tolerance compensation function, which is capable of being properly deformed and absorbing a processing tolerance within a range of an elastic region even when a distance between MEMS structures is changed due to the processing tolerance of the MEMS structures, being deformed to a minimum and rolled while maintaining a smooth contact with the MEMS structures by uniformly dispersing vertical loads applied from the MEMS structures through a plurality of the bearings, and thus minimizing the occurrence of abrasion and preventing damage to the bearing, and a method of manufacturing the same are provided. The roller bearing includes a roller bearing having a C-shaped section structure in which a gap having a specific interval is formed on one side of the roller bearing.
Type:
Grant
Filed:
December 26, 2012
Date of Patent:
March 10, 2015
Assignee:
Industry-Academic Cooperation Foundation Yonsei University
Abstract: A rope-conveyor structure for supporting plates of a wind or water power generator, in which plates are coupled to a rope at positions spaced apart from each other so that the force of flowing water or wind applied to the plates rotates the rope. The rope-conveyor structure includes couplings which are coupled to the rope between the plates, and connection wires each of which has a predetermined length. Each connection wire is connected at a first end thereof to the corresponding coupling and at a second end thereof to the corresponding plate. The positions of the connection wires can be selectively changed so that each connection wire can support the corresponding plate in either directions. Therefore, the plates can be prevented from being displaced from the correct positions or from twisting, regardless of the direction of flow of the water.
Type:
Grant
Filed:
November 9, 2011
Date of Patent:
March 10, 2015
Assignee:
Inje Univ. Industry-Academic Cooperation Foundation
Abstract: The present invention relates to a chitosan capsule in which a soluble active ingredient is encapsulated in a matrix containing chitosan and phytic acid; a cross-linking method and materials capable of being used in preparing the capsule; and pharmaceutical, food and cosmetic compositions comprising the capsule. The chitosan capsule according to the present invention is prepared via ionic gelation of chitosan as a biodegradable polymer with phytic acid capable of rapidly and effectively forming a cross-linking reaction with the chitosan polymer. The capsule of the present invention shows high encapsulation efficiency for a soluble active ingredient and protects the soluble active ingredient from being damaged in a digestive tract, resulting in improving an in vivo delivery efficiency of a physiologically active material.
Type:
Grant
Filed:
October 19, 2012
Date of Patent:
March 10, 2015
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Ji Yong Park, Chan Min Jeong, Min Kyung Lee, Sung Won Choi, Young Hee Cho, Hoon Ok Jeong
Abstract: An electrode stimulation delivery system is described having a unit and a network of wireless remote electrodes configured for implantation within a plurality of spaced apart locations in the tissue, e.g. myocardium, of a patient. The control unit is configured to be positioned at or subcutaneous to the patient's skin, and includes a processor, an antenna configured for delivering RF energy in proximity to the plurality of wireless remote electrodes, and programming executable on the processor for wirelessly communicating to the network of wireless remote electrodes via the delivered RF energy to individually control pacing of the plurality of wireless remote electrodes. Each of the plurality of wireless remote electrodes comprises a metamaterial-based biomimetic harvesting antenna comprising a Van Atta array zero-phase transmission lines to receive the RF energy to power activation of the plurality of wireless remote electrodes.
Type:
Grant
Filed:
October 29, 2013
Date of Patent:
March 10, 2015
Assignees:
NDSU Research Foundation, University of North Dakota
Inventors:
Daniel Ewert, Benjamin Braaten, Cody Satterlee, Brian Schwandt, Sheyann Harrison, Christopher Yost, Joshua Wynne
Abstract: A method of preparing a cyclohexasilane compound from trichlorosilane is provided. The method includes contacting trichlorosilane with a reagent composition to produce a compound containing a tetradecahalocyclohexasilane dianion, such as a tetradecachlorocyclohexasilane dianion. The reagent composition typically includes (a) tertiary polyamine ligand; and (b) a deprotonating reagent, such as a tertiary amine having a pKa of at least about 10.5. Methods of converting the tetradecahalocyclohexasilane dianion-containing compound to cyclohexasilane or a dodecaorganocyclohexasilane are also provided.
Type:
Grant
Filed:
January 25, 2011
Date of Patent:
March 10, 2015
Assignee:
NDSU Research Foundation
Inventors:
Arumugasamy Elangovan, Kenneth Anderson, Philip R. Boudjouk, Douglas L. Schulz
Abstract: A jig includes a wafer including an accommodation groove configured to accommodate a capacitive micromachined ultrasonic transducer (cMUT) when flip chip bonding is performed, and a separation groove formed in a bottom surface of the accommodation groove, the separation groove having a bottom surface that is spaced apart from thin films of the cMUT that face the bottom surface of the separation groove when the cMUT is seated on portions of the bottom surface of the accommodation groove.
Type:
Grant
Filed:
June 25, 2013
Date of Patent:
March 10, 2015
Assignees:
Samsung Electronics Co., Ltd., Kyungpook National University Industry-Academic Cooperation Foundation
Inventors:
Young Il Kim, Bae Hyung Kim, Jong Keun Song, Seung Heun Lee, Kyung Il Cho, Yong Rae Roh, Won Seok Lee