Abstract: A silica precursor having a selective adsorptivity with respect to cobalt ions is disclosed. The silica precursor includes a cross-linked 2,6-diamino pyridine group obtained by using 2,6-diamino pyridine, phosgene and 3-aminopropyltriethoxysilane.
Type:
Grant
Filed:
September 5, 2012
Date of Patent:
March 3, 2015
Assignee:
Pusan National University Industry—University Cooperation Foundation
Inventors:
Chang-Sik Ha, Sang Hyun Lee, Sung Soo Park
Abstract: A method of processing frames obtained by multiple exposures may include categorizing, by at least one processor, a plurality of frames captured by multiple exposures into one of a reference frame and a target frame, compensating for global motion resulting from motion of a capturing apparatus capturing an object, and compensating for local motion resulting from motion of the object, based on a joint histogram between the reference frame and the target frame.
Type:
Grant
Filed:
May 31, 2011
Date of Patent:
March 3, 2015
Assignees:
Samsung Electronics Co., Ltd., SNU R&DB Foundation
Inventors:
Kyoung Mu Lee, Young Su Moon, Yong Seok Heo, Joon Hyuk Cha, Shi Hwa Lee
Abstract: A method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery. Controlled delivery of an anti-inflammatory, chemopreventive drug is achieved by an enzyme-triggered drug release mechanism via degradation of encapsulated hydrogels. The hydro- and organo-gelators are synthesized in high yields from renewable resources by using a regioselective enzyme catalysis and a known chemopreventive and anti-inflammatory drug, curcumin, is encapsulated in the gel matrix and released by enzyme triggered delivery. The release of the drug occurs at the physiological temperature and control of the drug release rate is achieved by manipulating the enzyme concentration and temperature. The by-products formed after the gel degradation clearly demonstrated the site specificity of degradation of the gelator by enzyme catalysis.
Type:
Grant
Filed:
November 24, 2008
Date of Patent:
March 3, 2015
Assignee:
Research Foundation of the City University of New York
Abstract: The present embodiments provide a stent graft having a tubular configuration defining a lumen therethrough, the stent graft having a proximal section and a distal section. A folded section is positioned between the proximal section and the distal section. The folded section includes a first fold directed toward the distal end and engaged with the proximal section and a second fold directed toward the proximal end and engaged with the distal section. A valve arrangement is positioned in at least one of the first and second folds providing access from an exterior of the graft to the interior of the stent graft for insertion of an additional device.
Type:
Grant
Filed:
December 20, 2012
Date of Patent:
March 3, 2015
Assignee:
The Cleveland Clinic Foundation
Inventors:
Roy K. Greenberg, Karl J. West, Stephen Benefit
Abstract: A pharmaceutical composition for treating tuberculotic diseases with no side effect/low side effect is provided by the present invention, which pharmaceutically effective amount of one or more compounds chosen from isoniazid, rifampin, pyrazinamide and ethambutol, and pharmaceutically effective amount of substances which can reduce the side effect of the antituberculosis agents.
Type:
Grant
Filed:
April 20, 2011
Date of Patent:
March 3, 2015
Assignee:
National Defense Education and Research Foundation
Inventors:
Oliver Yaopu Hu, Tonho Young, Chenghuei Hsiong, Wenliang Chang, Tungyuan Shih, Hsintien Ho
Abstract: Polymer compositions, methods of making polymer compositions, structures (e.g., textile articles) having the polymer composition covalently bonded to the structure, methods of attaching the polymer to the surface of the structure having —OH functionality (e.g., Calkyl—OH), methods of decreasing the amount of microorganisms formed on a structure, and the like, are provided herein.
Type:
Grant
Filed:
October 12, 2012
Date of Patent:
March 3, 2015
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: Messages are delivered in a mobile network by creating a communication route between a source node and a destination node comprised of virtual routers, each virtual router being fixed to a particular geographical area and including a plurality of mobile nodes, each of the mobile nodes being available to forward a data packet on behalf of a virtual router, and each mobile node upon receiving a data packet sent over the communication route monitoring for forwarding of the data packet by another mobile node and, if such forwarding is not detected, the mobile node forwarding the data packet.
Type:
Grant
Filed:
August 14, 2008
Date of Patent:
March 3, 2015
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Disclosed herein is a wearable robot with improved operability and mobility through improvement of the upper limb structure thereof. The wearable robot includes an upper limb muscular power assist device to perform an articulation motion with a predetermined degree of freedom, the upper limb muscular power assist device being wearable by a user, and a mobile platform connected to the upper limb muscular power assist device to move according to information regarding movement speed and movement direction of the user in a rolling fashion. Consequently, mobility of the wearable robot and operation efficiency of the user are improved.
Type:
Grant
Filed:
March 7, 2013
Date of Patent:
March 3, 2015
Assignee:
Foundation of Soongsil University-Industry Cooperation
Abstract: Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of the central nervous system that are of viral, bacterial or idiopathic origin, including neural dysfunction caused by spinal cord injury. Neuromodulatory agents are set forth that include and comprise a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, a hapten, active fragments thereof, agonists thereof, mimics thereof, monomers thereof and combinations thereof. Methods are described for treating demyelinating diseases, and diseases of the central nervous system of humans and domestic animals, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, active fragments thereof and the like.
Type:
Grant
Filed:
March 7, 2013
Date of Patent:
March 3, 2015
Assignees:
Mayo Foundation for Medical Education & Research, Acorda Therapeutics, Inc.
Inventors:
Elliot A. Gruskin, Eric Chojnicki, Arthur E. Warrington, Allan J. Bieber, Moses Rodriguez
Abstract: A stent comprises (a) a first segment that is radially compressible and expandable and (b) a second segment that is substantially rigid in a radial direction. The second segment is bendable to assume a curved configuration while remaining substantially rigid in the radial direction and thereby resisting radial compression and expansion.
Abstract: Disclosed herein are an apparatus and a method for driving a gyroscope sensor. The apparatus for driving a gyroscope sensor includes: a detection module; a phase conversion module; an inversion module; a switch module selecting and outputting any one of the driving voltage and the inversion voltage for each axis; a driving module supplying driving voltage of a driving axis at the time of the driving and supplying inversion voltage at the time of stopping the driving; and a control unit passing the driving voltage of the driving axis by controlling the switch module according to a switching control signal at the time of the driving and passing the inversion voltage of each axis by controlling the switch module according to the switching control signal at the time of stopping the driving.
Type:
Grant
Filed:
April 3, 2012
Date of Patent:
March 3, 2015
Assignees:
Samsung Electro-Mechanics Co., Ltd., Korea University of Technology and Education, Industry-University Cooperation Foundation
Abstract: A micro electro mechanical system device has a first subassembly having sensor element including a coupler, and a second subassembly including a comb drive. The comb drive having stator plates and rotor plates and the coupler configured to displace the rotor plates relative to the stator plates providing a variable capacitance dependent on the displacement of the rotor plate.
Abstract: The present invention relates to a technique of using monocytic blood cells to effectively culture and proliferate blood adult stem cells and progenitor cells that only exist in small quantities to effectively obtain large quantities of stem cells. According to the present invention, the limitation of being able to derive only small quantities of stem cells from blood can be overcome, and the pluripotency of stem cells can easily be obtained.
Type:
Grant
Filed:
August 8, 2011
Date of Patent:
March 3, 2015
Assignee:
Seoul National University R&DB Foundation
Inventors:
Young-Bae Park, Hyo-Soo Kim, Hyun-Jae Kang, Hyun-Jai Cho, Jin Hur, Jong-Han Park
Abstract: The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell. The assays are comprised of two particles linked via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected visually or using various sensors, and the diagnostic results can be correlated with cancer prognosis.
Type:
Grant
Filed:
March 3, 2009
Date of Patent:
March 3, 2015
Assignee:
Kansas State University Research Foundation
Inventors:
Stefan H. Bossmann, Deryl L. Troyer, Matthew T. Basel
Abstract: A system and method is provided for radiation system collimation and design. A plurality of channel waveguide assemblies are provided to be operatively associated with respective beam collimators having varying longitudinal bore diameters. The plurality of channel waveguide assemblies includes a plurality of guides and concentric spacers. The plurality of guides and concentric spacers include varying inner diameters that are configured to be securably nested together by decreasing inner diameters and secured within the longitudinal bores of the respective beam collimators.
Abstract: A method for processing an audio signal is disclosed. The method for processing an audio signal includes frequency-transforming an audio signal to generate a frequency-spectrum, deciding a weighting per band corresponding to energy per band using the frequency spectrum, receiving a masking threshold based on a psychoacoustic model, applying the weighting to the masking threshold to generate a modified masking threshold, and quantizing the audio signal using the modified masking threshold.
Type:
Grant
Filed:
May 25, 2009
Date of Patent:
March 3, 2015
Assignees:
LG Electronics Inc., Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Hyen-O Oh, Chang Heon Lee, Jeongook Song, Yang Won Jung, Hong Goo Kang
Abstract: Described herein are compounds, and pharmaceutically acceptable salts and prodrugs thereof, which are useful as inhibitors of IMPDH. In certain embodiments, a compound of the invention selectively inhibits a parasitic IMPDH versus a host IMPDH. Further, the invention provides pharmaceutical compositions comprising one or more compounds of the invention. The invention also relates to methods of treating various parasitic and bacterial infections in mammals. Moreover, the compounds may be used alone or in combination with other therapeutic or prophylactic agents, such as anti-virals, anti-inflammatory agents, antimicrobials and immunosuppressants.
Type:
Grant
Filed:
March 22, 2010
Date of Patent:
March 3, 2015
Assignees:
Brandeis University, University of Georgia Research Foundation, Inc., The Brigham and Women's Hospital, Inc.
Inventors:
Lizbeth K. Hedstrom, Gregory D. Cuny, Deviprasad R. Gollapalli, Boris Striepen, Suresh Kumar Gorla, Mandapati Kavitha
Abstract: An apparatus for examining membrane-bound proteins in a cell can include a chamber with an insulating partition dividing the chamber into an upper well and a lower well, and a pore penetrating the insulating partition. The pore can have a size and shape so as to snugly hold a cell in place therein. The apparatus can further include circuitry for delivering a radio frequency signal to the cell. A belt electrode for delivering electrical signals to the cell can be located within the insulation partition and substantially encircling the pore. A measuring circuit for measuring cell membrane impedance to the radio frequency signal is also provided, and changes in the impedance can signal a change in state of a protein in the cell membrane.
Abstract: An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a captured valve leaflet and draw the suture through the leaflet. Proper leaflet capture can be confirmed with a fiber optic imaging system.
Type:
Grant
Filed:
February 19, 2010
Date of Patent:
March 3, 2015
Assignee:
Mayo Foundation for Medical Education and Research