Patents Assigned to Foundation
  • Controlled flow of a thin liquid film by electrowetting
    Patent number: 8632670
    Abstract: Apparatus and methods for controllably wetting a microstructured surface.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: January 21, 2014
    Assignee: Purdue Research Foundation
    Inventors: Suresh V. Garimella, Hemanth Kumar Dhavaleswarapu, Niru Kumari
  • Two photon tracer, method for the preparation thereof and the use thereof in screening anticancer agents
    Patent number: 8632749
    Abstract: Disclosed herein are compounds useful as two-photon tracers. Also, methods are provided for visualizing intracellular glucose uptake, screening anticancer agents, and diagnosing cancer using the compounds. They exhibit preferential uptake by cancer cells, penetrability sufficient to allow bright section images, high water solubility, high pH resistance and low toxicity in addition to applicability to living cells in deep tissues over a long period of time.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: January 21, 2014
    Assignee: SNU R&DB Foundation
    Inventors: Seung Bum Park, Bong Rae Cho, Hyang Yeon Lee, Jong Min Park
  • Therapeutic agents for the treatment of leukemia
    Patent number: 8633161
    Abstract: The invention provides for methods of treating a mammal who has a BCR/ABL-mediated leukemia, including chronic myelogenous leukemia (CML), particularly the blast crisis stage of CML, Philadelphia-positive acute lymphoblastic leukemia (Ph?-ALL), and refractory leukemias. The invention also provides for compounds for the treatment of these leukemias and methods of identifying anti-leukemic agents.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: January 21, 2014
    Assignee: The Ohio State University Research Foundation
    Inventors: Danilo Perrotti, Paolo Neviani, Ramasamy Santhanam, John C. Byrd, Guido Marcucci, Natarajan Muthusamy, Ching-Shih Chen
  • Human facilitating cells
    Patent number: 8632768
    Abstract: The present disclosure relates to human facilitating cells (hFC), and methods of isolating, characterizing, and using such hFCs.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: January 21, 2014
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Suzanne T. Ildstad, Mary Jane Elliott
  • Stem cells treated by in vitro fucosylation and methods of use
    Patent number: 8633021
    Abstract: A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method, an effective amount of an ?1,3-fucosyltransferase, e.g., ?1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic stem cells to convert non-functional PSGL-1 or other ligands on the cell surface into functional forms that bind selectins, especially P-selectin or E-selectin. The treated cells have enhanced effectiveness in reconstituting bone marrow in patients in need of such therapy.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: January 21, 2014
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Lijun Xia, Rodger P. McEver
  • Compositions and uses thereof
    Patent number: 8633192
    Abstract: Compositions and their use in the treatment or prevention of hyperglycemia and related diseases or disorders are disclosed.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: January 21, 2014
    Assignee: TIMA Foundation
    Inventors: Markus Matuschka-Greiffenclau, Haruhiko Inufusa
  • Vein closure and injection kits and methods
    Patent number: 8632520
    Abstract: Kits, apparatus, devices and methods for treating varicose veins caused by an incompetent venous junction (e.g., the saphenofemoral and/or saphenopopliteal junctions) are disclosed. The kits may include a sheath, a vein closure device, and an injection device. Alternatively, a vein closure device may include an integral injection channel and injection device. Methods may include injecting a vein with a sclerosing agent through a needle that extends in a direction that is not aligned with a longitudinal axis of a sheath or shaft.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: January 21, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Clark C. Otley
  • Cell repair and regeneration by suramin and related polysulfonated napthylureas
    Patent number: 8633250
    Abstract: Disclosed herein are compositions and methods for promoting the repair and regeneration of injured tissues, such as injuries resulting from ischemic damage.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: January 21, 2014
    Assignee: MUSC Foundation for Research Development
    Inventors: Rick G. Schnellmann, Shougang Zhuang
  • Method and system of restoring flow of traffic through networks
    Patent number: 8634301
    Abstract: An algorithm is presented, which may be used to generate LSPs for path-oriented virtual circuit networks. The algorithm maximizes throughput of traffic-flow through the network according to certain constraints which may selected to suit various scenarios and recovery schemes. The algorithm may be used by network operators to maximize financial profit from existing networks which has a predetermined bandwidth capacity.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: January 21, 2014
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Reuven Cohen, Gabi Nakibly
  • Nanocomposite materials comprising metal-organic-framework units and methods of using same
    Patent number: 8633331
    Abstract: The present invention relates to nanocomposite materials comprising: graphite-based material dispersed among transition metal-organic framework (MOF) units, wherein the graphite-based material is chemically linked to MOF units; wherein the graphite-based material is present in the range of about 5 wt. % to about 60 wt. % of the composite material.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: January 21, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Teresa J. Bandosz, Camille Petit
  • RECOMBINANT ADENOVIRUS EXPRESSING ALPHA-A-CRYSTALLIN GENE AND GENE THERAPY FOR RETINALVASCULAR DISEASE USING THE SAME
    Publication number: 20140017203
    Abstract: The present invention relates to a recombinant adenovirus expressing an ?A-crystallin gene, and gene therapy for retinal vascular disease using the recombinant adenovirus. Gene therapy using the recombinant adenovirus comprising an ?A-crystallin gene of the present invention increases the expression level of the ?A-crystallin gene in the damaged retinal pericytes to suppress pericyte loss and death, retinal vascular leakage, and leukocyte adhesion surrounding retinal vessels, thereby protecting the pericytes. Therefore, it can be used for the prevention and treatment of various retinal vascular diseases including diabetic retinopathy.
    Type: Application
    Filed: January 20, 2012
    Publication date: January 16, 2014
    Applicant: Industry-Academic Cooperation Foundation Gyeongsang National University
    Inventors: Wan Sung Choi, Eun Mi Hwang, Jae Yong Park, Gyeong Jae Cho, Young Hee Kim, So Yun Park
  • WHITE-EMITTING MONOMOLECULAR COMPOUND USING EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER, ORGANIC ELECTROLUMINESCENT ELEMENT AND LASER DEVICE USING THE SAME
    Publication number: 20140018543
    Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
    Type: Application
    Filed: September 12, 2013
    Publication date: January 16, 2014
    Applicants: SNU R&DB Foundation, Dongwoo Fine-Chem Co., Ltd.
    Inventors: Soo Young Park, Sang Hyuk Park, Ji Eon Kwon
  • METHODS AND COMPOSITIONS RELATED TO NEUROACTIVE THIAZOLINE COMPOUNDS
    Publication number: 20140018400
    Abstract: In one aspect, the invention relates to compounds having a general structure: and methods of using same to modulate calcium release. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: October 14, 2011
    Publication date: January 16, 2014
    Applicant: University of Utah Research Foundation
    Inventors: Eric W. Schmidt, Zhenjian Lin, Rowena R. Antemano, Alan Light, Baldomero M. Olivera, Gisela P. Concepcion
  • METHOD FOR ENGINEERING PROTEASES AND PROTEIN KINASES
    Publication number: 20140017764
    Abstract: Provided are methods for protein engineering, such as engineering proteases or kinases. The methods may utilize yeast display and/or ER sequestration of proteins or substrates. In some aspects, TEV proteases with altered substrate specificity, potency, and/or efficiency are provided.
    Type: Application
    Filed: June 25, 2013
    Publication date: January 16, 2014
    Applicant: Research Development Foundation
    Inventors: Brent L. IVERSON, George GEORGIOU, Joseph M. TAFT, Li YI
  • METHOD AND AN APPARATUS FOR PROCESSING AN AUDIO SIGNAL
    Publication number: 20140019143
    Abstract: An apparatus for processing an audio signal and method thereof are disclosed. The present invention includes receiving, by an audio processing apparatus, an audio signal including a first data of a first block encoded with rectangular coding scheme and a second data of a second block encoded with non-rectangular coding scheme; receiving a compensation signal corresponding to the second block; estimating a prediction of an aliasing part using the first data; and, obtaining a reconstructed signal for the second block based on the second data, the compensation signal and the prediction of aliasing part.
    Type: Application
    Filed: August 6, 2013
    Publication date: January 16, 2014
    Applicant: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Hyen-O Oh, Chang Heon Lee, Hong Goo Kang, Jung Wook Song
  • CONCURRENT EXECUTION OF CRITICAL SECTIONS BY ELIDING OWNERSHIP OF LOCKS
    Publication number: 20140019692
    Abstract: Critical sections of multi-threaded programs, normally protected by locks providing access by only one thread, are speculatively executed concurrently by multiple threads with elision of the lock acquisition and release. Upon a completion of the speculative execution without actual conflict as may be identified using standard cache protocols, the speculative execution is committed, otherwise the speculative execution is squashed. Speculative execution with elision of the lock acquisition, allows a greater degree of parallel execution in multi-threaded programs with aggressive lock usage.
    Type: Application
    Filed: September 17, 2013
    Publication date: January 16, 2014
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Ravi Rajwar, James R. Goodman
  • APPARATUS AND METHOD FOR INTERPOLATING IMAGE, AND APPARATUS FOR PROCESSING IMAGE USING THE SAME
    Publication number: 20140016870
    Abstract: An image interpolation apparatus is provided which includes an edge area distinguishing part configured to distinguish an edge area including an edge from an image; an edge area classifying part configured to classify the edge area into a plurality of regions; and an interpolation part configured to perform interpolation the regions in different manners.
    Type: Application
    Filed: November 20, 2012
    Publication date: January 16, 2014
    Applicant: Industry-Academic Cooperation Foundation, Yonsei Univesity
    Inventor: Industry-Academic Cooperation Foundation, Yonsei University
  • TRANSGENIC ALGAE FOR DELIVERING ANTIGENS TO AN ANIMAL
    Publication number: 20140017272
    Abstract: Delivery systems and methods are provided for delivering a biologically active protein to a host animal. The systems and methods provided include obtaining an algal cell transformed by an expression vector, the expression vector comprising a nucleotide sequence coding for the biologically active protein, operably linked to a promoter. In one illustrated embodiment, the biologically active protein is an antigenic epitope and upon administration to the animal the algal cell induces an immune response in the host animal.
    Type: Application
    Filed: January 2, 2013
    Publication date: January 16, 2014
    Applicants: The Ohio State University Research Foundation, ALGAEOMICS LLC
    Inventor: Richard T. Sayre
  • MODE-SYNTHESIZING ATOMIC FORCE MICROSCOPY AND MODE-SYNTHESIZING SENSING
    Publication number: 20140020141
    Abstract: A method of analyzing a sample that includes applying a first set of energies at a first set of frequencies to a sample and applying, simultaneously with the applying the first set of energies, a second set of energies at a second set of frequencies, wherein the first set of energies and the second set of energies form a multi-mode coupling. The method further includes detecting an effect of the multi-mode coupling.
    Type: Application
    Filed: May 20, 2013
    Publication date: January 16, 2014
    Applicants: University of Tennessee Research Foundation, UT-Battelle, LLC
    Inventors: Ali Passian, Thomas George Thundat, Laurene Tetard
  • METHODS OF USE TO ORALLY AND TOPICALLY TREAT ACNE AND OTHER SKIN CONDITIONS BY ADMINISTERING A 19-NOR CONTAINING VITAMIN D ANALOG WITH OR WITHOUT A RETINOID
    Publication number: 20140018332
    Abstract: Oral and topical pharmaceutical compositions, kits and methods of treatment thereof for treating various skin disorder including acne, psoriasis, ichthyosis, photoaging, photodamaged skin, and, skin cancer.
    Type: Application
    Filed: September 23, 2013
    Publication date: January 16, 2014
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Margaret Clagett-Dame, Hector F. DeLuca, Nircaq J. Nieves, Lori A. Plum, Mary E. Kaiser