Patents Assigned to Foundation
  • SPONTANEOUSLY IMMORTALIZED PROSTATE CANCER CELL LINE
    Publication number: 20140017721
    Abstract: This disclosure provides prostate cancer cell lines established from spontaneously immortalized, extremely tumorigenic and clonogenic primary prostate tumor. These cell lines represent unique cancer cell and cancer stem cell (CSC) models for preclinical prostate cancer studies and CSC-targeted drug development, which is of high value for pharmaceutic companies producing anti-cancer agents, as well as for the broad range of basic and translational research focused on cancer cell and CSC biology, stem cell behavior, cancer development and metastasis.
    Type: Application
    Filed: July 15, 2013
    Publication date: January 16, 2014
    Applicant: The Research Foundation of State University of New York
    Inventor: Galina I. Botchkina
  • HANDOVER APPARATUS AND METHOD IN A HETEROGENEOUS WIRELESS COMMUNICATION SYSTEM
    Publication number: 20140016618
    Abstract: A method and apparatus are provided for handing over from a Long Term Evolution (LTE) network to a Circuit Switching (CS) network by a call manager in a wireless communication system. The method includes receiving, from an Enhanced Node B (ENB) of the LTE network, a handover required message for a Packet Switching (PS) to CS handover from the LTE network to the CS network, when the PS to CS handover is decided based on measurement reports of a User Equipment (UE); sending, to a Mobile Switching Center (MSC) of the CS network, a PS to CS handover request message including an International mobile subscriber identity (IMSI) for identifying the UE and a target IDentifier (ID) for a target cell of the CS network; receiving a PS to CS handover response message from the MSC; and sending, to the UE via the ENB, a handover command message.
    Type: Application
    Filed: September 16, 2013
    Publication date: January 16, 2014
    Applicants: Industry-Academic Cooperation Foundation, Yonsei University, Samsung Electronics Co., Ltd.
    Inventors: Eun-Hui BAE, Sung-Ho CHOI, Osok SONG, Tae-Sun YEOUM, Han-Na LIM, Jai-Yong LEE, Hyun-Duk JUNG, Kyung-Min KIM
  • UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION
    Publication number: 20140018541
    Abstract: Unsymmetrical bisazides containing chelating and non-chelating azido groups undergo chemoselective three-component copper(I)-catalyzed azide-alkyne conjugation reactions with two different alkyne molecules. In conjunction with the reactivity gap between aromatic and aliphatic alkynes, a bistriazole molecule can be generated with an excellent regioselectivity by mixing two alkynes and a bisazide in a single reaction container. This method is applicable in aqueous solutions at neutral pH, which may lend utilities in bioconjugation applications.
    Type: Application
    Filed: July 15, 2013
    Publication date: January 16, 2014
    Applicant: The Florida State University Research Foundation, Inc.
    Inventors: Lei Zhu, Zhao Yuan, Gui-Chao Kuang
  • METHODS FOR REGULATING GELATION OF POLYSACCHARIDE SOLUTIONS AND USES THEREOF
    Publication number: 20140017210
    Abstract: The present invention provides a method for preparing chitosan solutions to allow regulating the conditions in which the chitosan solution will gel. The present invention also provides methods for using chitosan solutions as compositions and for using chitosan solutions in vitro and in vivo.
    Type: Application
    Filed: September 16, 2013
    Publication date: January 16, 2014
    Applicant: University of Virginia Patent Foundation
    Inventors: Cato T. Laurencin, Lakshmi Sreedharan Nair
  • CELL DRIVEN BY ELECTRIC FIELD AND OPERATION METHOD THEREOF
    Publication number: 20140016174
    Abstract: There is provided a cell driven by an electric field including a first electrode and a second electrode spaced from each other and an actuator moving between the first electrode and the second electrode. The actuator does not have permanent electric charges and a DC voltage or a pulse voltage is applied to the first electrode and the second electrode.
    Type: Application
    Filed: November 7, 2011
    Publication date: January 16, 2014
    Applicant: Korea University Research and Business Foundation
    Inventors: Mun Pyo Hong, Hong Choi, Hyo Joo Park, Ho Won Yoon
  • Method for Determining Hepatocellular Carcinoma Subtype and Detecting Hepatic Cancer Stem Cells
    Publication number: 20140018409
    Abstract: Described herein are methods of determining an HCC subtype in a subject which includes a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. Also described are methods of detecting HCC stem cells in a sample, and methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells.
    Type: Application
    Filed: June 12, 2013
    Publication date: January 16, 2014
    Applicants: The Government of the United States of America, as represented by the Secretary of the Department of, The Ohio State University Research Foundation
    Inventors: Xin Wei Wang, Junfang Ji, Taro Yamashita, Carlo M. Croce
  • Method for isolating hepatitis A virus or spring viremia of carp virus
    Patent number: 8628916
    Abstract: A method for isolating Hepatitis A virus or Spring viremia of Carp virus. A virus probe is prepared by linking a magnetic bead-conjugated Protein G with an anti-HAV (Hepatitis A Virus) antibody or an anti-rhabdovirus antibody. The virus probe is contacted with a sample to be analyzed to form a virus probe-virus complex. The virus probe-virus complex is then isolated. It may specifically isolate Hepatitis A virus or Spring viremia of Carp virus from a sample mixed viruses.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: January 14, 2014
    Assignee: Industry Foundation of Chonnam National University
    Inventors: Du Woon Kim, Hee Min Lee, Se Young Cho, Sang Mu Ko, Kyung Seo Oh, Joseph Kwon, Jong Soon Choi
  • System and method for quantifying fragile X mental retardation 1 protein in tissue and blood samples
    Patent number: 8628934
    Abstract: A system and method for the detection and quantification of fragile X mental retardation protein (FMRP) in human tissue and blood samples. The system includes several high avidity monoclonal antibodies that may be provided on Xmap microspheres to capture FMRP from a tissue or blood specimen. The resulting complex is reacted with a polyclonal anti-FMRP rabbit antibody and then mixed with an anti-rabbit IgG antibody conjugated to phycoerythrin. Fluorescence emitted from the resulting complex is a function of the amount of FMRP present in the specimen.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: January 14, 2014
    Assignee: The Research Foundation For Mental Hygiene, Inc.
    Inventors: Giuseppe LaFauci, William T. Brown, Richard Kascsak
  • Nanofilaments of catalytic materials for chemical process improvements
    Patent number: 8629189
    Abstract: A Fischer-Tropsch process including the steps of providing a reactor having a substrate element with a surface and a plurality of elongated micro-structures of catalyst material attached to the substrate surface The catalyst material includes at least one of cobalt, iron, or ruthenium and the micro-structures have a width of less than about 1 um and a length at least five times the width. A carbon compound and hydrogen are injected into the reactor such that at least a portion of the carbon compound and hydrogen contact the catalyst material. The carbon compound and hydrogen are reacted with the catalyst at a temperature between about 150° F. and about 400° F.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 14, 2014
    Assignee: Louisiana Tech University Research Foundation, a Division of Louisiana Tech University Foundation, Inc.
    Inventors: Chester Wilson, John McDonald, Joshua Brown
  • adhesion molecule
    Patent number: 8629249
    Abstract: A polypeptide, designated as “Streptococcus uberis Adhesion Molecule” (SUAM), and fragments of SUAM, prevent internalization and adherence of Streptococcus uberis and other streptococcal pathogens to cells. The SUAM polypeptide and fragments may be used diagnostically and therapeutically. Nucleic acid sequences encoding the SUAM polypeptide and fragments are included in the invention.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: January 14, 2014
    Assignee: University of Tennessee Research Foundation
    Inventors: Stephen P. Oliver, Raul A. Almeida, Douglas A. Luther, Hee-Myung Park
  • Back-projection of a projection image data set with depth-dependent filtering
    Patent number: 8630474
    Abstract: For filtered back-projection of a projection image data set, the projection image data set is cosine-weighted. The cosine-weighted projection image data set within the image plane of the projection image data set is subjected to a two-dimensional Radon transformation. The Radon transform of the cosine-weighted projection image data set differentiated with respect to the distance from an image origin of an image coordinate system. The derivative of the Radon transform is redundancy-weighted. The redundancy-weighted derivative is subjected to a two-dimensional Radon back-transformation. The Radon back-transform is differentiated and back-projected with respect to an image column coordinate. A differentiation step width entering into the differentiation is varied depending on depth.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: January 14, 2014
    Assignees: Siemens Aktiengesellschaft, University of Utah Research Foundation
    Inventors: Frank Dennerlein, Frederic Noo
  • Expression vector containing the major envelope protein P9 of cystovirus PHI6 as a fusion partner, and process for producing a membrane protein using the same
    Patent number: 8628939
    Abstract: The present invention relates to a membrane protein expression vector containing the major envelope protein P9 of Cystovirus phi6 as a fusion partner, to cells transformed by the expression vector, and to a process for producing membrane proteins using the cells. Target proteins can be effectively expressed by the expression vector of the present invention.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: January 14, 2014
    Assignee: Foundation of Soongsil University—Industry Cooperation
    Inventors: Dong-bin Lim, Yuna Jung
  • Use of megalin in urine as marker for detecting renal disorder
    Patent number: 8628930
    Abstract: This invention provides a simple means for detecting a renal disorder, a diagnostic marker for a renal disorder that enables prognostic prediction of a renal disorder (e.g., diabetic nephropathy and IgA nephropathy) and evaluation of the degree of nephropathy at the phase of stage-II diabetic nephropathy by measuring the megalin level in urine associated with a renal disorder used for the detection means, and use of such marker. The invention also provides the use of human megalin obtained from the urine sample of a subject as a marker for detecting a renal disorder.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: January 14, 2014
    Assignees: Niigata University, Juntendo Education Foundation, Denka Seiken Co., Ltd.
    Inventors: Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Shinya Ogasawara, Hiroyuki Kurosawa, Yoshiaki Hirayama
  • Method for producing olefins
    Patent number: 8629312
    Abstract: The present invention provides a method to produce olefins by the decarboxylation of organic carboxylic acids in the presence of an organopalladium catalyst.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: January 14, 2014
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: George A. Kraus
  • Systems and methods for treating disorders by selectively activating and/or blocking muscles through intrafasicular stimulation of the pudendal nerve
    Patent number: 8630711
    Abstract: Methods and related systems for treating patients suffering from several disorders including bladder dysfunction, erectile dysfunction, and bowel elimination disorders are disclosed and described. The method can include identification of the disorder followed by the step of accessing a pudendal nerve of the patient. A microelectrode array having a plurality of electrodes thereon is inserted into the pudendal nerve of the patient. A controller is electronically associated with the microelectrode array which is programmed to provide selective activation and/or blocking of various muscles using the microelectrodes of the array. The selective stimulation can be tuned to selectively activate or block at least one muscle selected from the group consisting of the external urethral sphincter, the detrusor muscle, the anal sphincter, and the cavernous smooth musculature of the penis.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: January 14, 2014
    Assignee: University of Utah Research Foundation
    Inventors: Heather A. C. Wark, Patrick C. Cartwright, Richard A. Normann
  • Micro-fluidic device for drug delivery
    Patent number: 8628517
    Abstract: A microfluidic device is provided for delivering a drug to an individual. The microfluidic device includes a body that defines a reservoir for receiving the drug therein. A valve interconnects the reservoir to an output needle that is insertable into the skin of an individual. A pressure source urges the drug from the reservoir toward the needle. The valve is movable between a closed position preventing the flow of the drug from the reservoir to the output needle and an open position allowing for the flow of the drug from the reservoir to the output needle in response to a predetermined condition in the physiological fluids of the individual.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: January 14, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David J. Beebe, Michael J. MacDonald, David T. Eddington, Glennys A. Mensing
  • Offending frequency suppression in hearing aids
    Patent number: 8630437
    Abstract: Adaptive notch filters can be used to estimate offending frequencies caused by feedback within a hearing aid system. The offending frequencies can be suppressed by filtering. Offending frequencies can be identified based on variability of the adaptive notch filter parameters.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: January 14, 2014
    Assignee: University of Utah Research Foundation
    Inventors: Ashutosh Pandey, V. John Mathews
  • Scalable video encoding/decoding method and apparatus thereof with overriding weight value in base layer skip mode
    Patent number: 8630352
    Abstract: Provided is a scalable video encoding method and apparatus, in which in adaptive reference fine grain scalability (AR-FGS) of scalable video coding, a weight value that is greater than a previous weight value provided for each slice overrides the previous weight value in order to generate a reference block for a enhancement layer when a macroblock mode of a base layer is a skip mode.
    Type: Grant
    Filed: July 4, 2007
    Date of Patent: January 14, 2014
    Assignees: Electronics and Telecommunications Research Institute, Industry Academic Cooperation Foundation Kyunghee University
    Inventors: Se-Yoon Jeong, Gwang-Hoon Park, Min-Woo Park, Seung-Pyo Shin, Doug-Young Suh, Kyung-Ae Moon, Jin-Woo Hong
  • Method for producing ethanol from xylose
    Patent number: 8628944
    Abstract: Disclosed is a method for producing ethanol from xylose using a recombinant Saccharomyces cerevisiae strain transformed to express a xylose reductase that uses NADH as a cofactor and a xylitol dehydrogenase that uses NAD+ as a cofactor, which are coupled with each other. The method provides an increase in ethanol yield and production efficiency, as compared to a control group, and enables production of ethanol at higher yield and high production efficiency by further eliminating acetaldehyde dehydrogenase which mediates production of acetic acid (by-product).
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: January 14, 2014
    Assignee: SNU R&DB Foundation
    Inventors: Jin-Ho Seo, Yong-Cheol Park
  • Purine nucleoside phosphorylase as enzymatic activator of nucleoside prodrugs
    Patent number: 8628767
    Abstract: A process for inhibiting a mammalian cancerous cell or virally infected cell includes providing a Trichomonas vaginalis purine nucleoside phosphorylase enzyme or a tail mutant purine nucleoside phosphorylase enzyme in proximity to the mammalian cancerous cell or the virally infected cell and exposing the enzyme to a purine nucleoside phosphorylase enzyme cleavable substrate to yield a cytotoxic purine analog. The process includes introducing to the cell a vector containing the phosphorylase enzyme, or a DNA sequence coding for the same and delivering to the cell an effective amount of the substrate such as 9-(?-D-arabinofuranosyl)-2-fluoroadenine (F-araA).
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: January 14, 2014
    Assignees: The UAB Research Foundation, Southern Research Institute
    Inventors: William B. Parker, Eric J. Sorscher