Abstract: Materials and Methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.
Type:
Grant
Filed:
December 10, 2010
Date of Patent:
November 19, 2013
Assignees:
Regents of the University of Minnesota, Iowa State University Research Foundation, Inc.
Inventors:
Daniel F. Voytas, Adam Bogdanove, Feng Zhang, Michelle Christian, Tomas Cermak, Clarice Lauer Schmidt, Erin Doyle, Li Wang
Abstract: A method, system and machine-readable medium are provided for watermarking natural language digital text. A deep structure may be generated and a group of features may be extracted from natural language digital text input. The deep structure may be modified based, at least partly, on a watermark. Natural language digital text output may be generated based on the modified deep structure.
Type:
Grant
Filed:
April 14, 2006
Date of Patent:
November 19, 2013
Assignees:
AT&T Intellectual Property II, L.P., Perdue Research Foundation
Inventors:
Mikhail Mike Atallah, Srinivas Bangalore, Dilek Z. Hakkani-Tur, Giuseppe Riccardi, Mercan Topkara, Umut Topkara
Abstract: A method of modulating and/or demodulating a signal in a communication system and a terminal for demodulating a signal received from a base station are provided. A terminal includes a singular value extractor to extract at least one singular value of a channel matrix associated with a channel that is formed between a base station and the terminal, a modulation order determination unit to determine a modulation order based on the at least one singular value, and a received signal demodulator to demodulate a received signal according to the determined modulation order.
Type:
Grant
Filed:
September 1, 2008
Date of Patent:
November 19, 2013
Assignees:
Samsung Electronics Co., Ltd., Purdue Research Foundation
Inventors:
Jung Hoon Suh, Sung Jin Kim, David J. Love
Abstract: Disclosed herein is the use of terrestrial plant materials (e.g., leaves and bark) that contain biopolymer materials to produce hydrocarbon-rich crude oils that can be refined further into hydrocarbon-based biofuels, via the hydrous pyrolysis method, which involves heating to subcritical temperatures and pressures in an aqueous medium. One can also isolate the aliphatic biopolymers and utilize them as feedstocks for production of the hydrocarbon-rich crude via hydrous pyrolysis.
Type:
Grant
Filed:
May 14, 2012
Date of Patent:
November 19, 2013
Assignee:
Old Dominion University Research Foundation
Abstract: A scheduling method in a distributed antenna system is provided. Each of a plurality of Mobile Stations (MSs), respectively corresponding to each subchannel, are classified as a Single Transmission (ST) MS or a Cooperative Transmission (CT) MS according to a CT criterion. An MS with a maximum channel capacity is selected from among the classified MSs. Resources are allocated to a corresponding subchannel when the selected MS is the ST MS, and resources are allocated using a CT scheduling technique when the selected MS is the CT MS. The classifying, selecting and allocating steps are repeated until allocation of resources is completed.
Type:
Grant
Filed:
April 6, 2009
Date of Patent:
November 19, 2013
Assignees:
Samsung Electronics Co., Ltd, Industry-University Cooperation Foundation Sogang University
Abstract: Disclosed are fusion proteins comprising a biologically active molecule and an immunoglobulin (Ig) Fc domain which is linked to the biologically active molecule. The Fc domain is a hybrid human Fc domain of (i) IgG1, IgG2 or IgG4 or (ii) IgG4 and IgD. The hybrid Fc is useful as a carrier of biologically active molecules.
Type:
Grant
Filed:
November 19, 2010
Date of Patent:
November 19, 2013
Assignees:
Genexine, Inc., Postech Academy-Industry Foundation of Phohang University of Science and Technology (Postech)
Abstract: Systems, methods and devices to measure and potentially promote thermogenesis, preferably non-exercise activity thermogenesis are disclosed. In the various embodiments, the present invention may rely on one or more sensors that detect a subject's body posture and/or activity. Feedback regarding the subject's posture and/or activity (relative to preferred postures and/or activity levels) may preferably be provided after the data is retrieved and analyzed. A power interlock may also be used to control delivery of electrical energy based on a subject's posture and/or activity level.
Type:
Grant
Filed:
May 4, 2006
Date of Patent:
November 19, 2013
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
James A. Levine, Paul H. Kane, Chinmay U. Manohar
Abstract: The invention relates to early flowering Chia (Salvia hispanica L.) strains that are suitable for culturing in a temperate area for seed production. Mutations are introduced to wild type chia seeds. Desired mutant progeny having normal appearance and an altered flora organ development is subsequently identified.
Type:
Grant
Filed:
October 30, 2009
Date of Patent:
November 19, 2013
Assignee:
University of Kentucky Research Foundation
Inventors:
David Hildebrand, Watchareewan Jamboonsri, Timothy Phillips
Abstract: This document provides live non-pathogenic M. bovis bacteria and compositions containing live non-pathogenic M. bovis bacteria. This document also provides methods of using live non-pathogenic M. bovis bacteria to immunize cattle against infectious diseases (e.g., diseases caused by M. bovis bacteria). In addition, methods and materials that can be used to generate live non-pathogenic M. bovis bacteria are provided.
Type:
Grant
Filed:
June 3, 2009
Date of Patent:
November 19, 2013
Assignees:
Iowa State University Research Foundation, Inc., Biotechnology Research and Development Corporation
Abstract: Disclosed is a method and apparatus for linearizing a power amplifier using a digital signal process (DSP), and particularly, is a method and apparatus for effectively linearizing an amplifier which has a plurality of distortion generating sources. To this end, there is a plurality of compensation methods and compensation units which can generate inverse distortion signals corresponding to the distortion components outputted by the plurality of distortion generating sources, thereby making it possible to provide superior linearity.
Abstract: Disclosed herein is an apparatus for the separation of proteins, comprising a capillary isoelectric focusing unit (2) for primarily separating protein samples on the basis of pI; and a hollow fiber flow field flow fractionation unit (4), connected to one side of the capillary isoelectric focusing unit (2), for secondarily separating the protein samples. The apparatus allows proteins to be separated on the basis of pI and molecular weight without denaturation and can further be applied for the identification of proteins in conjunction with nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry after enzymatic digestion of the protein fractions.
Type:
Grant
Filed:
January 17, 2007
Date of Patent:
November 19, 2013
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University
Abstract: A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
Type:
Grant
Filed:
August 26, 2010
Date of Patent:
November 19, 2013
Assignee:
The Cleveland Clinic Foundation
Inventors:
J. Luis Lujan, Ashu Chaturvedi, Cameron C. McIntyre
Abstract: A method for analysis of cardiac rhythm and RR interval time series based on entropy related data and entropy based measures. The information is related to but distinct from entropy, and is derived from histograms of interval match counts in which the y-axis is the frequency of intervals of length in that have the match count given on the x-axis. The phenotype of the histogram informs on the presence of atrial fibrillation or, in the presence of sinus rhythm, the degree of congestive heart failure.
Type:
Grant
Filed:
February 4, 2009
Date of Patent:
November 19, 2013
Assignee:
University of Virginia Patent Foundation
Abstract: In accordance with the invention there are devices and processes for making ceramic nanofiber mats and ceramic filters for use in high temperature and in corrosive environments. The process for forming a ceramic filter can include electrospinning a preceramic polymer solution into a preceramic polymer fiber having a diameter from about 10 nm to about 1 micron and forming a preceramic polymer fiber web from the preceramic polymer fiber onto a collector. The process can also include pyrolyzing the preceramic polymer fiber web to form a ceramic nanofiber mat having a diameter less than the diameter of the preceramic polymer fiber, the ceramic nanofiber mat comprising one or more of an oxide ceramic and a non-oxide ceramic such that the ceramic fiber mat can withstand temperature greater than about 1000 ° C.
Type:
Grant
Filed:
March 12, 2008
Date of Patent:
November 19, 2013
Assignee:
Univesity of Florida Research Foundation, Inc.
Inventors:
Wolfgang M. Sigmund, Vasana Maneeratana, Paolo Colombo, Chang-Yu Wu, Hyoungjun Park, Qi Zhang
Abstract: A transmitter system for transmitting parallel data by compensating a crosstalk includes: first and second transmission lines parallel to each other; a first inverted crosstalk pulse generation unit configured to receive first transmission data and inverted first transmission data and output a first inverted crosstalk pulse according to a data mode; a second inverted crosstalk pulse generation unit configured to receive second transmission data transmitted in parallel to the first transmission data and inverted second transmission data and output a second inverted crosstalk pulse according to the data mode; a first addition unit configured to combine the first transmission data and the second inverted crosstalk pulse and output first compensation data to be transmitted to the first transmission line; and a second addition unit configured to combine the second transmission data and the first inverted crosstalk pulse and output second compensation data to be transmitted to the second transmission line.
Abstract: A method and system of accelerating the acquisition and reconstruction of magnetic resonance images. Magnetic resonance imaging (“MRI”) data is acquired from a plurality of coils using parallel MRI (“pMRI”). The MRI data represents a reduced field-of-view (“FOV”) image for each of a plurality of coils. The MRI data is further undersampled by sequentially applying a compressed sensing (“CS”) technique, such as SparseMRI. The undersampled, reduced FOV images are then reconstructed into a final magnetic resonance image using a pMRI reconstruction technique, such as SENSitivity encoding (“SENSE”). This combination of MR image acquisition, sampling, and reconstruction is referred to as CS-SENSE.
Abstract: The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C disorders, including diseases and disorders mediated by GPCRs.
Type:
Grant
Filed:
June 13, 2008
Date of Patent:
November 19, 2013
Assignee:
University of Florida Research Foundation, Inc.
Abstract: A peripheral device comprises a first entity and a second entity. In operation, the first/second entities are configured to respectively: receive a first/second entity-related message from at least one other device to indicate the availability of the at least one other device for attachment, send, to the at least one other device, a first/second entity-related message indicating the availability for communication with the at least one other device, receive, from the at least one other device, a first/second entity-related signal including a first/second entity-related peripheral device identifier, send a first/second entity-related response to the at least one other device, receive, from the at least one other device, a first/second entity-related device response, and send, to the at least one other device, a first/second entity-related second peripheral response including the first/second entity-related peripheral device identifier.
Abstract: Methods and systems for a differential compressed sensor to form a smart optical imager that uses both active (laser) and passive (ambient light) to sample the direct image information within a three-dimensional spatial frame. The lens-based distance sensor is produces smart sampling of target by adjusting the size of the laser beam spot on the target sampling grid to produce a boundary outline by a light flooding. This target dependent direct sampling of the target results in direct compressed sensing. A passive light acquisition pin-hole sampling optical sensor design is proposed that produces the pixel-basis Laplacian to determine the compressed sensed pixels in the incident image.
Type:
Grant
Filed:
March 16, 2011
Date of Patent:
November 19, 2013
Assignee:
University of Central Florida Research Foundation, Inc.