Abstract: This invention discloses 2?-methyl-19-nor-vitamin D analogs, and specifically 2?-methyl-19-nor-1?-hydroxy-homopregnacalciferol and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Abstract: Apparatus, methods and systems for production of high efficiency refractive and diffractive elements by providing a photo-sensitizer free multicomponent glass, exposing the multi component glass to pulsed laser radiation to produce refractive indexed modulation, and heating the exposed multicomponent silicate glass to produce the high efficiency refractive and diffractive elements. The pulsed laser radiation is infrared femtosecond pulses to ultraviolet nanosecond pulses which provide ionization of glass matrix. The multicomponent glass is a photosensitive glass with high transparency in ultraviolet spectral region, e.g. silicate glass which includes silver, fluorine and bromine and does not contain photosensitizers such as cerium and antimony, PTR glass, cerium free PTR glass and cerium+antimony free PTR glass.

Abstract: Disclosed herein are an electromagnetic bandgap structure and a printed circuit board having the same. The bandgap structure includes a conductive layer including a plurality of conductive plates, a first metal layer disposed under the conductive layer and including a first stitching pattern electrically connected to a first conductive plate of the plurality of conductive plates, and a second metal layer disposed under the first metal layer and including a second stitching pattern electrically connected to both the first stitching pattern and a second conductive plate of the plurality of conductive plates. The bandgap to structure includes stitching patterns formed in two layers different from the conductive layer, thus offering a stop-band having a desired bandwidth in a compact structure.

Abstract: The present invention relates to a system for authentication management of a sensor node having a subscription processing function, and a method for operating the system. Upon receiving information about a sensor node allocated with an IP address, the system supports the access of only authorized user equipment to a corresponding sensor node, which blocking any direct access of unauthorized user equipment to the sensor node, thereby strengthening the security of the sensor node. According to the present invention, a relay server receives subscription information from user equipment. The relay server checks permission validity of corresponding user equipment. If the user equipment has a valid permission, the relay server transmits the subscription information to a sensor node, and transmits subscription acceptance information to the user equipment. Then the sensor node transmits the collected and stored information to the user equipment having a valid permission.

Abstract: A novel marker for diagnosis of liver cancer and use thereof are provided. To be specific, a marker for diagnosis of liver cancer using over-expression of NLK (neuro-like kinase) in liver cancer cell is provided, along with a composition for diagnosis of liver cancer, a kit, a microarray, and a method for diagnosing liver cancer using the marker. Additionally, a method for screening a substance to prevent or treat liver cancer by decreasing expression of the marker gene or protein, and a composition for preventing or treating liver cancer including such substance are provided. Accordingly, the NLK gene can be efficiently used as a target for diagnosis and treatment of liver cancer.

Abstract: A system and method for performing parallel magnetic resonance angiography includes controlling operation of a magnetic gradient system and an RF system to perform a calibration data pulse sequence to begin acquiring calibration data for use in a parallel imaging reconstruction process after receiving an indication that the subject has received a dose of a contrast agent. The acquisition of the calibration data is discontinued before the contrast agent reaches a peak concentration within a region of interest (ROI) of the subject and operation of the magnetic gradient system and RF system is controlled to perform an imaging pulse sequence in accordance with a parallel imaging acquisition to begin acquiring image data from the ROI. The image data is reconstructed into an image of the ROI using the calibration data.

Abstract: The present invention relates to the use of novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), for treating brain diseases and injuries that result in dopaminergic deficiencies and mitochodrial dysfunction, e.g., reduced complex I enzyme activity.

Abstract: An error compensation method for multi-axis controlled machines generates an error compensation model for compensating for geometric error of a multi-axis controlled machine by separating an error matrix of a tool tip from an error synthesis model of a multi-axis controlled machine and calculates an error compensation value using the error compensation model and an inverse kinematic model so that the error matrix becomes an identity matrix. The error compensation method can reduce calculation error and calculation time due to complicated numerical analysis and compensate for error in the multi-axis controlled machine, regardless of its configuration.

Abstract: There is provided a dihydroquinazoline compound of the formula or a pharmaceutically acceptable salt thereof, wherein the values of the radicals are defined herein, as well as a pharmaceutical composition containing the compound, and a method of using the compound for the treatment of Alzheimer's disease.

Abstract: A system and method of scheduling tasks, comprising receiving activity and performance data from registers or storage locations maintained by hardware and an operating system; storing calibration coefficients associated with the activity and performance data; computing an energy dissipation rate based on at least the activity and performance data; and scheduling tasks under the operating system based on the computed energy dissipation rate.

Abstract: Semiconductor emitting devices that offset stresses applied to a quantum well region and reduce internal fields due to spontaneous and piezoelectric polarizations are disclosed. In one embodiment, a semiconductor emitting device includes a quantum well region comprising an active layer that emits light and at least one barrier layer disposed adjacent the active layer, a means for impressing an electric field across the quantum well region to inject carriers into the quantum well region, and a means for impressing an offset electric field across the quantum well region to offset the polarization field formed in the quantum well region.

Abstract: Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods.

Abstract: An interactive, multi-user media delivery system having a number of media storage mediums, each of containing a particular media selection, and a number of media players structured to selectively deliver the media selection to users. Each of the media players includes a control assembly structured to selectively control and regulate delivery of the media selection to the user, and at least one of the media players is selectively designatable as a slave unit. A master control assembly is further provided and is operatively associated with the media players, a connectivity assembly being included to establish a communicative link at least between the slave unit(s) and the master control assembly. The master control assembly is further structured to receive synchronization data from each of the media players, and to simultaneously and uniformly control the delivery of the media selection by the media players.

Abstract: An apparatus and method for suppressing color rolling are provided. The apparatus includes a digital signal processor which detects first motion information on a current frame and second motion information on at least one of a plurality of neighboring frames, calculates a gain based on the first and second motion information, and applies the gain to at least one channel of the current frame.

Abstract: The present invention provides metal silicide nanowires, including metallic, semiconducting, and ferromagnetic semiconducting transition metal silicide nanowires. The nanowires are grown using either chemical vapor deposition (CVD) or chemical vapor transport (CVT) on silicon substrates covered with a thin silicon oxide film, the oxide film desirably having a thickness of no greater than about 5 nm and, desirably, no more than about 2 nm (e.g., about 1-2 nm). The metal silicide nanowires and heterostructures made from the nanowires are well-suited for use in CMOS compatible wire-like electronic, photonic, and spintronic devices.

Abstract: A metrology probe capable of measurements of a broad range of physical properties of individual samples of nano- or sub-nanometer dimensions is provided. The probe comprises a probe body, a substrate connected to the probe body, and a tip proximate the substrate. The probe further comprises a coarse piezoelectric actuator having an electrical input. The coarse piezo is configured to cause the tip and/or the substrate to move relative to each other when a first electrical signal is provided to the electrical input. The probe further comprises a low-pass filter in electrical communication with the electrical input of the coarse piezo. The probe further comprises a fine piezoelectric actuator having an electrical input configured to cause the tip and/or the substrate to move relative to each other when a second electrical signal is provided to the electrical input.

Abstract: A method of determining the point-spread function (PSF) of an imaging system includes the steps of capturing image data, establishing an idealized source spot, establishing a functional form model, subtracting the captured image from the estimated image equation and determining a metric that measures the fit of the estimated image to the captured image. The functional form model may include both diffraction and aberration and stray light. The functional form model may be optimized to reduce the metric to an acceptable level.

Abstract: A NAND flash memory array, an operating method and a fabricating method of the same are provided. The NAND flash memory array has a cut-off gate line under a control gate in order to operate two cells having vertical channels independently with one control gate (i.e., a shared word line). The memory cell area is reduced considerably compared to the conventional vertical channel structure, and is better for high integration. A shared cut-off gate turn off is made during a programming operation and prevents programming the opposite cell by a self-boosting effect. It is possible to shield electrically with a shared word line (a control gate) during a reading operation, and minimizes the effect of storage condition of the opposite cell. Also, the NAND flash memory array can be fabricated by using the conventional CMOS process.

Abstract: A drug delivery vehicle for targeted delivery of a drug mimics viral properties of size, capsid-like protein capsule, cell-specific entry, toxin release, destruction of infected cells, and migration to neighboring cells. This vehicle, termed a virogel, contains a hydrophobic polymeric core, a hydrophilic inner shell, a hydrophilic outer shell, and a ligand. An illustrative drug-loaded virogel includes poly(L-histidine-co-phenylalanine) as the core, doxorubicin loaded in the core, polyethylene glycol as the inner shell, bovine serum albumin as the outer shell, and folic acid as the ligand.

Abstract: In a display device equipped with a light source device, a second light-guide member is provided to the back surface of a first light-guide member that has an emitted light control sheet provided to the front surface thereof. The emitted light control sheet is composed of a flat plate portion and protrusions. A first light source mounted to a side surface of the first light-guide member, and a second light source mounted to a side surface of a second light-guide member are switched and turned on. The emitted light control sheet has light-condensing effects when the first light source is on, and has diffusing effects when the second light source is turned on. The angle range of illuminating light can thereby be switched.