Abstract: The present disclosure relates to a laser diode system. The system may have at least one laser diode emitter having a substrate, at least one laser diode supported on the substrate, and a facet which a laser beam generated by the laser diode is emitted. A cooling subsystem is included which is disposed in contact with the substrate of the laser diode emitter. The cooling subsystem includes a plurality of cooling fins forming a plurality of elongated channels for circulating a cooling fluid therethrough to cool the laser diode emitter. The cooling fluid also flows over the facet of the laser diode emitter.
Type:
Grant
Filed:
April 9, 2021
Date of Patent:
April 16, 2024
Assignees:
Lawrence Livermore National Security, LLC, Colorado State University Research Foundation
Inventors:
Jack Kotovsky, Salmaan H. Baxamusa, Clint D. Frye, Ian Seth Ladner, Thomas M. Spinka, Devin Joseph Funaro, David Ryan Hobby, Caleb Del Anderson, Todd Bandhauer
Abstract: The present invention relates to a scanner having a flexible probe which is an apparatus capable of being utilized for an inspection on a weld zone of a general ferrite material and a stainless material and allowing an inspection to be performed on a fitting weld zone where it is difficult for a general phased array ultrasonic testing (PAUT) probe to approach.
Type:
Grant
Filed:
November 18, 2020
Date of Patent:
April 16, 2024
Assignees:
Foundation for Research and Business, Seoul National University of Science and Technology, Korea Inspection Eng.Co., Ltd
Inventors:
Ik Keun Park, Yu Min Choi, Seong Jin Lim, In Gon Jung, Hye Jin Park
Abstract: A group of reductive 2D materials (R2D) with extended reactive vacancies and a method for making the R2D with extended reactive vacancies are provided, especially the example of the reductive boron nitride (RBN). To create defects such as vacancies, boron nitride (BN) powders are milled at cryogenic temperatures. Vacancies are produced by milling, and the vacancies can be used to reduce various metal nanostructures on RBN. Due to the thermal stability of the RBN and the enhanced catalytic performance of metal nanostructures, RBN-metals can be used for different catalysts, including electrochemical catalysts and high temperature catalysts.
Type:
Grant
Filed:
June 11, 2021
Date of Patent:
April 16, 2024
Assignee:
The Penn State Research Foundation
Inventors:
Mauricio Terrones, Yu Lei, He Liu, Kazunori Fujisawa, Ana Laura Elias Arriaga, Tianyi Zhang, Rodolfo Cruz-Silva, Morinobu Endo, Xiaoxing Wang, Cynthia Guerrero-Bermea
Abstract: In one aspect, the disclosure relates to compounds useful to regulate, limit, or inhibit the expression of AVIL (advillin), methods of making same, pharmaceutical compositions comprising same, and methods of treating disorders associated with AVIL dysregulation using same. In aspects, the disclosed compounds, compositions and methods are useful for treating disorders or diseases in which the regulation, limitation, or inhibition of the expression of AVIL can be clinically useful, such as, for example, the treatment of cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Type:
Grant
Filed:
June 27, 2022
Date of Patent:
April 16, 2024
Assignee:
University of Virginia Patent Foundation
Abstract: An example of a bottlebrush polymer has a polymer backbone and a plurality of individual brush moieties bonded to the polymer backbone. The individual brush moieties include a ketone, a hydrophilic segment, and a surface adhesive terminal group. The brush moieties can be functionalized and/or cross-linked.
Type:
Grant
Filed:
January 15, 2021
Date of Patent:
April 16, 2024
Assignee:
Florida State University Research Foundation, Inc.
Abstract: The present invention relates to a novel use of NCKAP1 gene in neurodegenerative diseases. More specifically, the present invention relates to a marker composition for predicting the prognosis of a neurodegenerative disease, comprising a NCKAP1 protein or a gene encoding same, a composition and a kit for predicting the prognosis of a neurodegenerative disease, which comprises a formulation for measuring the level of the protein or an mRNA of the gene encoding same, and a pharmaceutical composition for preventing or treating neurodegenerative disease, comprising the protein or the gene encoding same as an active ingredient.
Type:
Grant
Filed:
August 23, 2018
Date of Patent:
April 16, 2024
Assignee:
Industry-University Cooperation Foundation Hanyang University
Inventors:
Seung Hyun Kim, Min Young Noh, Min Soo Kwon, Ki Wook Oh, Min Yeop Nahm, Soo Jung Lee
Abstract: The present disclosure relates to a composition for preventing or treating fibrosis including an inhibitor of cyclin-dependent kinase 17 (CDK17) expression or activity. According to the present disclosure, the inhibitor of CDK17 expression or activity significantly reduces collagen production and cell activity and viability in activated hepatic stellate cells (liver fibrosis cell model), renal tubular epithelial cells (renal fibrosis cell model) in which fibrosis is induced by TGF-? treatment, and alveolar epithelial cells (lung fibrosis cell model) in which fibrosis is induced by TGF-? treatment, indicating that the composition of the present disclosure has an excellent effect in preventing or treating fibrosis.
Type:
Grant
Filed:
May 31, 2022
Date of Patent:
April 16, 2024
Assignee:
Korea University Research and Business Foundation
Inventors:
Young Sik Lee, Do Hoon Lee, Min Seok Choi, Jae Sang Hong
Abstract: Methods and systems for imaging a target. In some examples, a system includes an optical modulator configured for applying, at each time of an exposure window, a respective optical modulation pattern to a received image of the target to output a modulated image. The system includes a camera configured for capturing a single image frame for the exposure window by receiving, at each of time, the modulated image of the target. The system includes a demodulator implemented on a computer system and configured for demodulating the single image frame based on the optical modulation patterns to recover a number of recovered image frames each depicting the target at a respective recovered time within the exposure window.
Type:
Grant
Filed:
January 22, 2019
Date of Patent:
April 16, 2024
Assignee:
University of Tennessee Research Foundation
Inventors:
Zhili Zhang, Mark Terrell Gragston, Cary Dean Smith
Abstract: Provided is an isolated population of human pluripotent stem cells comprising at least 50% human pluripotent stem cells characterized by an OCT4+/TRA1-60?/TRA1-81?/SSEA1+/SSEA4? expression signature, and novel methods of generating and maintaining same in a pluripotent, undifferentiated state a suspension culture devoid of cell clumps. Also provided are novel culture media, cell cultures and methods for culturing pluripotent stem cells in a suspension culture or a two-dimensional culture system while maintaining the cells in a proliferative, pluripotent and undifferentiated state. The novel culture media comprise interleukin 11 (IL11) and Ciliay Neurotrophic Factor (CNTF); bFGF at a concentration of at least 50 ng/ml and an IL6RIL6 chimera; or an animal contaminant-free serum replacement and an IL6RIL6 chimera. Also provided are methods for generating lineage-specific cells from the pluripotent stem cells.
Type:
Grant
Filed:
March 5, 2020
Date of Patent:
April 16, 2024
Assignee:
Technion Research & Development Foundation Limited
Abstract: A quantum key distribution system may include a transceiver including a state randomizer to impart a random state transformation to one or more qubits of a generated faint pulse and a quantum bit encoder to reflect the faint pulse back to the transceiver with one or more encoded bits. The transceiver may receive a return pulse through the communication channel, where the state randomizer reverses the random state transformation. The transceiver may include three or more detectors to measure the return pulse at time-gated timeslots associated with possible paths of the return pulse. Reception of the faint pulse from the quantum bit encoder as the return pulse triggers a detector in a first known subset of the detectors, while reception of a faked-state pulse from a third party as the return pulse results in a non-zero probability of triggering of a detector in a second known subset of the detectors.
Type:
Grant
Filed:
January 5, 2023
Date of Patent:
April 16, 2024
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Composition and electrode for phosphate sensing. In one embodiment, the composition includes a first component, a second component, and a third component. The first component is selected from a group consisting of cobalt oxide nanoparticles, tin (IV) chloride, diphenyl tin dichloride, and ammonium molybdate. The second component includes graphene oxide or reduced graphene oxide. The third component includes pyrrole or polypyrrole.
Type:
Grant
Filed:
August 10, 2018
Date of Patent:
April 16, 2024
Assignee:
UWM Research Foundation, Inc.
Inventors:
Woo-Jin Chang, Misong Ryu, Mohammad Rizwen Ur Rahman
Abstract: Methods of evaluating or providing a clonal profile of a subject interval, e.g., a subgenomic interval, or an expressed subgenomic interval (or of a cell containing the same), in a subject, are disclosed.
Type:
Grant
Filed:
December 4, 2015
Date of Patent:
April 16, 2024
Assignee:
Foundation Medicine, Inc.
Inventors:
Geoffrey Alan Otto, Michelle Nahas, Doron Lipson
Abstract: A device for detecting zone parallelity includes a detection control circuit configured to generate respective first and second requests for first and second zones among a plurality of zones included in a solid state drive (SSD). An SSD controller is configured to control the SSD by generating a first command and a second command corresponding to the first request and the second request, respectively, and to schedule the first command and the second command. The detection control circuit determines zone parallelity of the first and second zones using response characteristics of the responses of the SSD to the first request and the second request. The response characteristics may include a latency of a response.
Type:
Grant
Filed:
September 2, 2022
Date of Patent:
April 16, 2024
Assignees:
SK hynix Inc., Industry-Academic Cooperation Foundation, Dankook University
Abstract: Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having a spinal cord injury, a brain injury, or a neurological neuromotor disease are described.
Type:
Grant
Filed:
September 13, 2021
Date of Patent:
April 16, 2024
Assignees:
California Institute of Technology, University of Louisville Research Foundation, Inc., The Regents of the University of California
Inventors:
Victor Reggie Edgerton, Roland R. Roy, Yury Gerasimenko, Joel W. Burdick, Susan J. Harkema, Jonathan Hodes, Yu-Chong Tai, Mandheerej S. Nandra, Claudia A. Angeli, Thomas Anthony Desautels
Abstract: An inverse quantization method is implemented by an inverse quantization device, the method configured for acquiring quantized coefficients, estimating a quantization parameter in quantization groups or quantization parameter prediction group units, generating an inverse quantization matrix for adaptive quantization, and generating transform coefficients from the quantized coefficients using the quantization parameter and the inverse quantization matrix.
Type:
Grant
Filed:
November 16, 2022
Date of Patent:
April 16, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, Kwangwoon University Industry-Academic Collaboration Foundation
Inventors:
Dong Gyu Sim, Sea Nae Park, Jong Seok Lee, Seung Wook Park, Wha Pyeong Lim
Abstract: Provided are a method and a device, for processing spectrum data of an image sensor. The method includes obtaining spectrum response signals corresponding to channels of spectrum data of light, the spectrum data being obtained from an object by an image sensor; determining a set of bases corresponding to the obtained spectrum response signals; performing, based on the determined set of bases, a change of basis on at least one basis included in the determined set of bases; and generating, by using a pseudo inverse, reconstructed spectrum data from the spectrum response signals on which the change of basis has been performed.
Type:
Grant
Filed:
June 21, 2022
Date of Patent:
April 16, 2024
Assignees:
SAMSUNG ELECTRONICS CO., LTD., Korea University Research and Business Foundation
Inventors:
Suyeon Lee, Q-Han Park, Unjeong Kim, Hyunjun Ma
Abstract: An inverse quantization method is implemented by an inverse quantization device, the method configured for acquiring quantized coefficients, estimating a quantization parameter in quantization groups or quantization parameter prediction group units, generating an inverse quantization matrix for adaptive quantization, and generating transform coefficients from the quantized coefficients using the quantization parameter and the inverse quantization matrix.
Type:
Grant
Filed:
November 16, 2022
Date of Patent:
April 16, 2024
Assignees:
Hyundai Motor Company, Kia Corporation, Kwangwon University Industry-Academic Collaboration Foundation
Inventors:
Dong Gyu Sim, Sea Nae Park, Jong Seok Lee, Seung Wook Park, Wha Pyeong Lim
Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.
Type:
Grant
Filed:
June 14, 2021
Date of Patent:
April 16, 2024
Assignee:
Research Development Foundation
Inventors:
George Georgiou, Chang-Han Lee, Tae Hyun Kang
Abstract: A storage device includes at least one processor. The at least one processor is configured to acquire a surface scan image in an image tile format of a set size, bind a set number of image tiles in one segment, and store a plurality of segments as files, respectively, instead of storing the image tiles without modification.
Type:
Grant
Filed:
May 25, 2021
Date of Patent:
April 16, 2024
Assignee:
Pusan National University Industry—University Cooperation Foundation
Abstract: A new and distinct cultivar of Centipedegrass named ‘Tift TC458’ is provided. The new and distinct variety has excellent turf quality, increased seed head production, and increased nematode resistance as compared to similar commercial centipedegrass. The sexually and asexually reproduced diploid variety is reliably propagated both vegetatively and by seed.
Type:
Grant
Filed:
March 24, 2023
Date of Patent:
April 16, 2024
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
Wayne W. Hanna, Brian Schwartz, Sameer Khanal, J. Earl Elsner