Abstract: This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial effect.
Type:
Grant
Filed:
September 28, 2001
Date of Patent:
May 4, 2010
Assignees:
Quick-Med Technologies, Inc., University of Florida Research Foundation, Inc.
Inventors:
Christopher D. Batich, Gregory Schultz, Bruce A. Mast, Gerald M. Olderman, David S. Lerner, William Toreki
Abstract: A multi-input-multi-output (MIMO) communications system is provided for conveying signals over a MIMO channel. The system includes a precoder for precoding a signal based upon a uniform channel decomposition scheme. The system further comprises a transmitter in communication with the precoder for conveying the precoded signal over a subchannel of the MIMO channel.
Type:
Grant
Filed:
November 4, 2005
Date of Patent:
May 4, 2010
Assignee:
University of Florida Research Foundation, Inc.
Abstract: Tetraphosphorous ligands are combined with transition metal salts to form catalysts for use in hydroformylation, isomerization-hydroformylation, hydrocarboxylation, hydrocyan-ation, isomerization-formylation, hydroaminomethylation and similar related reactions.
Abstract: A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface.
Type:
Grant
Filed:
June 13, 2006
Date of Patent:
May 4, 2010
Assignee:
Research Foundation of State University of New York
Abstract: The invention provides method and compositions for the modulation of condensed tannin production in plants. The methods of the invention allow creation of plants having novel phenotypes. Increased expression of condensed tannins in plants may be used to increase the nutritional value of food plants for both human and animal consumption. Increased condensed tannin content also reduces the potential for bloat in animals fed certain forage plants low in condensed tannin content. The invention may also be used to modify plant pigmentation.
Abstract: A series of velocity encoded MR image frames are acquired. To increase the temporal resolution of the acquired image frames radial projections are acquired and each image frame is highly undersampled. The radial projections for each velocity encoding direction are interleaved throughout the scan and a composite phase image is reconstructed from these and used to reconstruct a velocity image for each image frame in a highly constrained backprojection method.
Type:
Grant
Filed:
September 28, 2006
Date of Patent:
May 4, 2010
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Charles A. Mistretta, Julia Velikina, Kevin Michael Johnson, Oliver Wieben
Abstract: A device for improved vision into or out of at least one eye of a subject. The device comprises an enclosing vessel for holding one or more lenses in front one or two eyes of the subject and for holding a substance whose refractive index is matched to the refractive index of the cornea. The vessel is adapted to seal the substance to the face around the eye or eyes of the subject thereby allowing focusing into or out of the eye or eyes.
Type:
Grant
Filed:
June 23, 2005
Date of Patent:
May 4, 2010
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: Disclosed is a multi-nozzle inkjet print head using an electrostatic field induced type. The inkjet print head in accordance with an embodiment of the present invention includes: a first electrode being formed in each nozzle; and a second electrode located on a side spaced from the nozzle and arranged to block between any two adjacent nozzles and inducing an electrostatic field for discharging ink from the nozzle by forming an electric potential difference between the first electrode and the second electrode.
Type:
Grant
Filed:
February 20, 2009
Date of Patent:
May 4, 2010
Assignee:
Sungkyunkwan University Foundation for Corporate Collaboration
Inventors:
Yong-Jae Kim, Suk-Han Lee, Jae-Yong Choi, Sang-Uk Son, Do-Young Byun, Han-Seo Ko, Ki-Chul An
Abstract: Phosphine triazole ligand compounds, prepared through click chemistry, complex with transition metals to form transition metal-phosphine triazole ligand complexes. These complexes are useful catalysts in coupling reactions such as Suzuki-Miyaura coupling, Stille coupling, Negishi coupling, Sonagashira coupling, carbon-heteroatom bond-forming reactions (C—O and C—N), alpha alkylation of carbonyls, Heck coupling reactions, and hydrogenation reactions.
Abstract: The present invention relates to a pharmaceutical composition comprising compound for induction of apoptosis, a method for inducing cancer cell apoptosis, a method to suppress lymphocyte activation, a method to improve intracellular trafficking of misfolded mutants and a screening method to identify additional compounds useful for inducing apoptosis, and more specifically, it relates to pharmaceutical compositions comprising imidazole derivatives as active gradients for induction of apoptosis to treat various diseases including cancers and immune-related diseases, the method of inducing apoptosis by treating cancer cells with the said pharmaceutical composition, the method of inactivating human lymphocytes by treating lymphocytes with the said pharmaceutical composition, the method of improving intracellular trafficking of misfolded mutants by treating cells containing the mutants with the said pharmaceutical composition, and the screening method for identifying additional compound useful for inducing apoptos
Type:
Application
Filed:
February 26, 2007
Publication date:
April 29, 2010
Applicant:
Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
In-Jae Shin, Myung-ryul Lee, Darren Williams
Abstract: Methods are disclosed for treating or preventing ophthalmic conditions related to a toxic visual cycle product. Compounds and compositions useful in these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said the therapeutic and prophylactic methods of the invention.
Type:
Application
Filed:
July 27, 2007
Publication date:
April 29, 2010
Applicant:
University of Florida Research Foundation, Inc.
Abstract: A method for clustering multi-dimensional data streams includes: when data elements are input, determining 1-D subclusters and assigning identifiers to the determined 1-D subclusters; (b) generating a matching set that is a set of identifiers of the 1-D subclusters where each dimensional value of the data elements belongs to the range of the 1-D subclusters of the corresponding dimensions; and (c) determining subclusters by finding a set of frequently co-occurring 1-D subclusters among a set of 1-D subclusters that belong to the generated matching set. With the present invention, the processing time required to find the subclusters can be improved and the performance of the memory is further improved.
Type:
Application
Filed:
September 22, 2009
Publication date:
April 29, 2010
Applicant:
Industry-Academic Cooperation Foundation, Yonsei University
Abstract: Embodiments of the subject invention relate to a Wingless Hovering Micro Air Vehicle (WHOMAV) and its Power Source Unit (PSU). Embodiments can operate at reasonable power levels for hovering and withstanding expected wind gusts. Embodiments of the subject invention can have a diameter less than 15 cm. Embodiments can have one or more smooth (continuous curvature) surface and can be operated using electromagnetic and electrohydrodynamic principles. The wingless design of specific embodiments can allow operation with no rotating or moving components. Additional embodiments can allow active response to the surrounding flow conditions. The issue of low lift to drag ratio and degradation of airfoil efficiency due to the inability of laminar boundary layers attachment can also be significantly reduced, or eliminated.
Type:
Application
Filed:
December 23, 2008
Publication date:
April 29, 2010
Applicant:
University of Florida Research Foundation, Inc.
Abstract: An apparatus and method for monitoring a beam position using an electrooptic effect are disclosed. The apparatus for measuring the position of a charged particle passing through the interior of an accelerator includes: a crystal positioned within the accelerator and allowing laser generated from a laser generating unit to pass therethrough; a polarization unit polarizing the laser that has passed through the crystal; and a measurement unit measuring the polarized state of the polarized laser to monitor the charged particle. The position of the charged particle passing through the interior of the accelerator can be more accurately measured.
Abstract: The present invention relates to a magnetic memory cell, which controls the magnetization direction of the free magnetic layer of a Magnetic Tunnel Junction (MTJ) device using a spin torque transfer, and enables the implementation of a magnetic logic circuit, in which memory and logic circuit functions are integrated. The magnetic memory cell includes an MTJ device (10) including a top electrode (11) and a bottom electrode (13), which are provided to allow current to flow therethrough, and a fixed layer (15) and a free layer (17), which are magnetic layers respectively deposited on a top and a bottom of an insulating layer (19), required to insulate the top and bottom electrodes from each other. A current control circuit (50) controls a flow of current flowing between the top and bottom electrodes, and changes a magnetization direction of the free layer according to an input logic level.
Type:
Application
Filed:
March 6, 2008
Publication date:
April 29, 2010
Applicant:
EWHA University-Industry Collaboration Foundation
Abstract: Polypeptides, compositions, and methods for treating shock are described. A isolated polypeptide, Deltorphin-E, can be administered without concomitant fluid resuscitation, before, concurrently with, or after the onset of shock or the occurrence of an event that creates a risk of shock. Deltorphin-E can be administered in accordance with the method as part of a preconditioning strategy, which reduces the extent of ischemic injury. Deltorphin-E can be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.
Type:
Grant
Filed:
June 6, 2007
Date of Patent:
April 27, 2010
Assignee:
University of Kentucky Research Foundation
Abstract: This invention discloses 2-methylene-19-nor-17-ene vitamin D analogs, and specifically 2-methylene-19-nor-1?-hydroxy-17-ene-homopregnacalciferol and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders and inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.
Type:
Grant
Filed:
July 9, 2007
Date of Patent:
April 27, 2010
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Hector F. DeLuca, Bulli Padmaja Tadi, Lori A. Plum, Margaret Clagett-Dame
Abstract: An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.
Type:
Grant
Filed:
May 22, 2007
Date of Patent:
April 27, 2010
Assignee:
The UAB Research Foundation
Inventors:
Tong Zhou, Kimihisa Ichikawa, Robert P. Kimberly, William J. Koopman, Jun Ohsumi, Albert F. LoBuglio, Donald J. Buchsbaum
Abstract: A novel medicament for treating neurodegenerative diseases, especially for ameliorating dyskinesia, comprising as an active ingredient selenoprotein P and/or a peptide fragment or a series of peptide fragments derived from said protein is provided. The novel medicament for treating neurodegenerative diseases, especially for ameliorating dyskinesia, according to the present invention is suitably applicable to diseases with decrease in motor function.
Type:
Grant
Filed:
April 24, 2008
Date of Patent:
April 27, 2010
Assignee:
Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
Abstract: A method of preventing and/or treating inflammatory bowel disease, particularly ulcerative colitis and Crohn's disease, is disclosed. The method involves administering a 2-methylene-19-nor-vitamin D compound in an amount effective to treat the disease. The administration of a 2-methylene-19-nor-vitamin D compound also prevents the development of or delays the onset of inflammatory bowel disease in susceptible individuals. The preferred compounds are 1?-hydroxy-2-methylene-19-nor-homopregnacalciferol and 2-methylene-19-nor-20(S)-1?,25-dihydroxyvitamin D3.
Type:
Grant
Filed:
October 8, 2003
Date of Patent:
April 27, 2010
Assignees:
Wisconsin Alumni Research Foundation, The Penn State Research Foundation