Patents Assigned to Foundation
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Publication number: 20090260101Abstract: The subject invention concerns materials and methods for providing plants or plant tissue with increased resistance to heat conditions. Increased resistance of a plant or plant tissue to heat conditions provides for decreased yield losses generally observed at elevated temperatures. One aspect of the invention concerns polynucleotides that encode a mutant plant small subunit of AGPase. The subject invention also comprises a mutant plant small subunit of AGPase encoded by a polynucleotide of the invention. The subject invention also concerns plants comprising a polynucleotide of the invention and method for making the plants.Type: ApplicationFiled: April 9, 2008Publication date: October 15, 2009Applicant: University of Florida Research Foundation, Inc.Inventors: L. Curtis Hannah, Nikolaos Georgelis
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Publication number: 20090258367Abstract: The present invention relates to a method of mapping of mRNA distribution, comprising the steps of a preparing a probe DNA attached to a apical liner region of the dendron on AFM cantilever where the probe DNA can specifically hybridize a target mRNA and measuring specific adhesive force between the probe DNA and the target mRNA on sectioned tissue at nanometer resolution.Type: ApplicationFiled: March 31, 2009Publication date: October 15, 2009Applicant: Postech Academy-Industry FoundationInventors: JOON WON PARK, YU JIN JUNG, YU SHIN PARK, HONG GIL NAM
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Publication number: 20090259020Abstract: Disclosed are compounds having the structure: wherein R1a and R1b are independently H, alkyl, F, or fluoroalkyl; wherein R2a, R2b, R2a?, and R2b? are independently H, alkyl, F, fluoroalkyl, aryl, or alkenyl; wherein R3 is OH, alkoxyl, NH2, alkylamino, or dialkylamino; wherein R4a and R4b are independently H, alkyl, acyl, or alkyloxycarbonyl; wherein R11, R12, R13, R21, R22, and R23 are independently H, alkyl, F, or fluoroalkyl; and wherein C0, C1, C2, and C2? are independently chiral or achiral. Also disclosed are processes for making a fluorinated ?-amino acid comprising the steps of: providing a diol; treating the diol with a thionyl halide with oxidative workup; reacting the product with an azide salt to yield an azido group; oxidizing the product to yield a carboxyl group; and reducing the azido group to yield an amino group. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: ApplicationFiled: September 14, 2007Publication date: October 15, 2009Applicant: University of Utah Research FoundationInventors: Bruce Yu, Zhong-Xing Jiang
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Publication number: 20090257907Abstract: SmCo-based alloy nanoparticles composed mainly of a SmCo-based alloy containing Sm and Co as constituent elements, wherein the content of metal elements other than Sm and Co is 0.05-20 wt % with respect to the SmCo-based alloy.Type: ApplicationFiled: March 4, 2009Publication date: October 15, 2009Applicants: TDK Corporation, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Mamoru Satoh, Naoki Toshima, Mutsuko Kinjo, Haruki Kinjo, Shiho Tokonami
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Publication number: 20090258315Abstract: The invention provides various photoacid generator compounds and ionic components thereof. Photoresist compositions that include the ions and non-ionic photoacid generator compounds are also provided. The invention further provides methods of making and using the photoacid generator compounds and photoresist compositions disclosed herein. The compounds and compositions are useful as photoactive components in chemically amplified resist compositions for use in, for example, various microfabrication applications.Type: ApplicationFiled: April 9, 2009Publication date: October 15, 2009Applicant: Cornell Research Foundation, Inc.Inventors: Christopher K. Ober, Yi Yi
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Publication number: 20090257723Abstract: An elongate imaging fiber bundle may include a plurality of elongate optical fibers coherently arranged in the bundle, the plurality including peripheral fibers at a periphery of the bundle and deep fibers deep to the peripheral fibers, and a coating surrounding the plurality of fibers. An exposed length of the bundle, intermediate the bundle's proximal and distal ends, may be chemically etched to be denuded of the coating, and peripheral fibers are so severed as to permit injection of light into the peripheral fibers at the exposed length. A fiberscope may include a fiber bundle having an exposed length that is denuded of the coating, and peripheral fibers are so severed in the exposed length as to permit injection of light into the peripheral fibers at the exposed length, and a light source so positioned with respect to the exposed length of the bundle as to inject light into the peripheral fibers at the exposed length.Type: ApplicationFiled: April 15, 2008Publication date: October 15, 2009Applicant: University Of Iowa Research FoundationInventors: Eman Namati, Jacqueline Thiesse Namati, Geoffrey McLennan
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Publication number: 20090257863Abstract: The ‘hydrokinetic turbine assembly’ is a device for the conversion of the kinetic energy of oscillating tidal currents into rotary torque to generate clean electric power. This device is a horizontal axis hydroturbine with a plurality of trapezoidal symmetrical blades placed at about 45 degrees to the axis. The inclination of the blades assures its maximum energy conversion capacity and the dual reaction function of the turbine where ‘floods and ebbs” are alternatively converted into rotary torque. The inner blade frame, its aerodynamic contour, and at least one connective circumferential blade-ring, add strength buoyancy and sensitivity to slow currents. This hydrokinetic turbine is separated from the electric generators and can be placed in pre-planned current flow locations for greater efficiency.Type: ApplicationFiled: January 30, 2009Publication date: October 15, 2009Applicant: Asia Power Dev. Foundation, Inc.Inventor: Roger Carraro Prioreschi
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Patent number: 7601341Abstract: The 121-amino acid isoform of vascular endothelial growth factor (VEGF121) is linked by a flexible G4S tether to a cytotoxic molecule such as toxin gelonin or granzyme B and expressed as a soluble fusion protein. The VEGF121, fusion protein exhibits significant anti-tumor vascular-ablative effects that inhibit the growth of primary tumors and inhibit metastatic spread and vascularization of metastases. The VEGF121 fusion protein also target osteoclast precursor cells in vivo and inhibits osteoclastogenesis.Type: GrantFiled: August 16, 2004Date of Patent: October 13, 2009Assignee: Research Development FoundationInventor: Michael Rosenblum
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Patent number: 7601884Abstract: A cloned animal is produced by demecolcine treatment characterized by culturing the nuclear transfer embryo in vitro and transferring the embryo in vivo. This significantly improves in vitro development of somatic cell nuclear transfer embryos and maintenance of pregnancy from transfer of transfer somatic cell nuclear transfer embryos in a surrogate mother up to delivery. A nuclear transfer embryo of a non-primate mammal made by enucleating a recipient oocyte; injecting a nuclear donor cell into the enucleated oocyte; fusing together the injected enucleated oocyte with the injected nuclear donor cell to form a fused oocyte; activating the fused oocyte; and treating the activated oocyte with demecolcine to form the nuclear transfer embryo.Type: GrantFiled: January 3, 2008Date of Patent: October 13, 2009Assignee: KNU - Industry Cooperation FoundationInventor: Eunsong Lee
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Patent number: 7600948Abstract: The present invention provides a permanent earth retaining wall having small diameter casings that remain in the ground to become vertical micropile soldier beams of the retaining wall, and a method for forming a retaining wall. The method includes a top-down method of constructing a retaining wall. The retaining wall may be constructed by placing a plurality of relatively small diameter micropile casings into the ground using overburden percussion drilling methods. The casings are configured to remain in the ground and form micropile soldier beams of the retaining walls. Tiebacks may be coupled to the micropiles via horizontal support wales that span multiple micropiles.Type: GrantFiled: October 19, 2006Date of Patent: October 13, 2009Assignee: Schnable Foundation CompanyInventors: Kevin W. Cargill, Stephen L. Dimino
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Patent number: 7601823Abstract: The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the ?-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors.Type: GrantFiled: October 24, 2005Date of Patent: October 13, 2009Assignees: Cornell University, The Research Foundation of State University of New YorkInventors: Li Niu, Zhen Huang, Hua Shi, John T. Lis
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Patent number: 7603631Abstract: A method, system and apparatus for the monitoring, diagnosis and evaluation of the state of a dynamic system is disclosed. This method and system provides the processing means for receiving sensed and/or simulated data, converting such data into a displayable object format and displaying such objects in a manner such that the interrelationships between the respective variables can be correlated and identified by a user. This invention provides for the rapid cognitive grasp of the overall state of a critical function with respect to a dynamic system. The system provides for displayed objects which change in real-time to show the changes of the functions of the system. It is a highly flexible system which works with a wide variety of applications, including biological systems, environmental systems, engineering systems, economic systems, mechanical systems, chemical systems and the like.Type: GrantFiled: May 7, 2004Date of Patent: October 13, 2009Assignee: University of Utah Research FoundationInventors: Julio C. Bermudez, Stefano Foresti, Dwayne R. Westenskow, James Agutter, Debra Gondeck-Becker
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Patent number: 7601167Abstract: An anchor is implantable into a bone in a patient's body and, when implanted, is resistant to toggling in the bone and to being pulled from the bone. The anchor includes a head end portion having a surface that extends transverse to a central axis of the anchor and is engagable with the bone. A plurality of helical spikes extend from the surface on the head end portion and are engagable with the bone. Each of the plurality of helical spikes has a helical central axis that forms a helix around the central axis of the anchor. Each of the plurality of helical spikes further has a circular cross-sectional configuration as viewed in a plane extending perpendicular to the helical central axis of each of the helical spikes and a distal end portion with a tip that penetrates the bone as the head end portion is rotated relative to the bone.Type: GrantFiled: September 12, 2005Date of Patent: October 13, 2009Assignee: The Cleveland Clinic FoundationInventor: Isador H. Lieberman
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Patent number: 7601358Abstract: Mycobacterium tuberculosis proteins and protein compositions that are components of a desaturase complex are provided. The Mycobacterium tuberculosis desaturase complex may include a desaturase and an oxidoreductase. The complex may include the rv3229c and rv3230c gene products of Mycobacterium tuberculosis. Vectors for expressing the desaturase and the oxidoreductase can be packaged together, including a label that indicates their use as a complex for analyzing desaturation of fatty acids. In addition, methods for screening target ligands specific for a desaturase complex are also provided.Type: GrantFiled: September 4, 2007Date of Patent: October 13, 2009Assignee: Wisconsin Alumni Research FoundationInventors: Brian G. Fox, Yong Chang
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Patent number: 7601357Abstract: Disclosed herein are novel methods for screening for compounds useful in treating or preventing tuberculosis. In exemplary embodiments, screening methods are based on the implementation or manipulation of triacylglycerol hydrolase like polypeptides or polynucleotides encoding the same. The methods are useful in identifying agents active against TB infection.Type: GrantFiled: November 20, 2006Date of Patent: October 13, 2009Assignee: University of Central Florida Research Foundation, Inc.Inventors: Pappachan E. Kolattukudy, Chirajyoti Deb, Jaiyanth Daniel
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Patent number: 7603635Abstract: A computer readable storage medium includes executable instructions to analyze an asynchronous, multi-rail digital circuit to identify a gating sub-circuit and a gated sub-circuit. The asynchronous, multi-rail digital circuit is transformed to segregate the gating sub-circuit and the gated sub-circuit.Type: GrantFiled: July 31, 2007Date of Patent: October 13, 2009Assignee: Institute of Computer Science (ICS) of the Foundation for Research & Technology Hellas, Foundation for Research and Technology Hellas (Forth)Inventors: Christos P. Sotiriou, Pavlos Mattheakis
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Patent number: 7603013Abstract: An elongate imaging fiber bundle may include a plurality of elongate optical fibers coherently arranged in the bundle, the plurality including peripheral fibers at a periphery of the bundle and deep fibers deep to the peripheral fibers, and a coating surrounding the plurality of fibers. An exposed length of the bundle, intermediate the bundle's proximal and distal ends, may be chemically etched to be denuded of the coating, and peripheral fibers are so severed as to permit injection of light into the peripheral fibers at the exposed length. A fiberscope may include a fiber bundle having an exposed length that is denuded of the coating, and peripheral fibers are so severed in the exposed length as to permit injection of light into the peripheral fibers at the exposed length, and a light source so positioned with respect to the exposed length of the bundle as to inject light into the peripheral fibers at the exposed length.Type: GrantFiled: April 15, 2008Date of Patent: October 13, 2009Assignee: University of Iowa Research FoundationInventors: Eman Namati, Jacqueline Thiesse Namati, Geoffrey McLennan
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Patent number: 7601346Abstract: Three choline utilizing strains of microorganisms isolated from the anthers of wheat, Aureobasidium pullulans strain AS 55.2, Arthrobacter species strain OH 221.3, and Pseudomonas species strain AS 64.4, are superior antagonists of F. graminearum. These microorganisms are effective for suppression and control of FHB in cereals, particularly in wheat and barley.Type: GrantFiled: December 15, 2006Date of Patent: October 13, 2009Assignees: The United States of America, as represented by the Secretary of Agriculture, The Ohio State University Research FoundationInventors: David A. Schisler, Naseem I. Khan, Michael J. Boehm, Patricia J. Slininger
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Patent number: 7601797Abstract: Methods of controlled hydrolysis/alcoholysis and regeneration of a borohydride are disclosed. Examples of the present invention show that hydrolysis of sodium borohydride or lithium borohydride with dilute acid provides simultaneous generation of H2 and boric acid for recycling. Other examples of the present invention show methods for regenerating a borohydride by reacting an aluminum hydride to a borate compound to provide a regenerated borohydride.Type: GrantFiled: May 10, 2005Date of Patent: October 13, 2009Assignee: Purdue Research FoundationInventors: P. Veeraraghavan Ramachandran, Debasis Hazra, Bhimapaka China Raju, Venkatram Reddy Mereddy, Annyt Bhattacharyya
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Patent number: 7601122Abstract: Ultrasonic strain measurements, which characterize the structure of tissue, may be obtained by combining multiple echo signals acquired at different compressions and at different angles. Such angular compounding may improve the quality of the elastic signal and provide at one time both an axial and lateral strain measurement.Type: GrantFiled: January 27, 2004Date of Patent: October 13, 2009Assignee: Wisconsin Alumni Research FoundationInventors: James A. Zagzebski, Tomy Varghese