Abstract: A method for fabricating nano-electro-mechanical tags for identification and authentication includes, in part, forming a protective layer above a substrate, forming a first conductive layer above the protective layer serving as a first electrode, forming a piezoelectric layer above the first conductive layer, forming a second conductive layer above the piezoelectric layer, patterning the second conductive layer to form a second electrode, patterning the piezoelectric layer to expose one or more portions of the first conductive layer, and forming one or more trenches that extends into a plurality layers formed above. In addition, a sacrificial layer can be formed above portions of the substrate, and the sacrificial layer can be removed by etching to release the nano-electro-mechanical tags from the substrate.

Abstract: The present invention relates to a Candida tropicalis cell line, which comprises a mutant gene, having improved tolerance for cytotoxicity of stromal cells, and a method for producing dicarboxylic acid using the Candida tropicalis cell line. The Candida tropicalis cell line for producing dicarboxylic acid developed according to the present invention has improved tolerance for existing stromal toxicity as well as significantly improved efficiency for producing dicarboxylic acid compared to existing cell lines, thus can be used in biological production of dicarboxylic acid and is expected to have high industrial utility.

Abstract: The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent.

Abstract: An image stitching method and apparatus are disclosed. The image stitching apparatus includes at least one processor and a memory. The processor may obtain a plurality of images at different viewpoints, estimate homographies of each of the plurality of images, generate an aligned image by aligning the plurality of images based on the homographies of each of the plurality of images, obtain a collective energy map by inputting the aligned image to a neural network, estimate a stitching line of the aligned image based on the collective energy map, and generate a stitched image by blending the aligned image based on the stitching line.

Abstract: An igniter system and method for igniting a propellant by an optical energy source. The igniter system including an igniter composite and a propellant. The igniter composite including a reactive component and a fluoropolymer. The propellant is coupled to the igniter composite. The igniter composite has a composition including nano-aluminum at ideal stoichiometry in polyvinylidene fluoride. The igniter composite is configured to achieve a sustained ignition from a wavelength emitted from the optical energy source. The wavelength is between around 250 nanometers to around 1100 nanometers.

Abstract: This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: The present invention relates to a positively-charged body for a triboelectric generator and a triboelectric generator including the same. More particularly, the present invention relates to a positively-charged body based on a two-dimensional material including silicon oxide, and to a triboelectric generator including such a positively-charged body. Thus, a conventional manner in which the positively-charged body is mainly composed of a metal thin film or polymer is not used, but the positively-charged body is made of the silicon oxide and the two-dimensional material. Thus, charge generation efficiency of the generator via contact between the positively-charged body and a negatively-charged body may be dramatically enhanced.

Abstract: Embodiments of the invention include a method for manufacturing sensors and circuit structures. The method can include providing a substrate including a layer of polymer capable of producing graphite in response to the application of energy, a first electrode adjacent to a first via location on the layer of polymer, and an insulating layer over at least a portion of the first electrode and the layer of polymer at the first via location; and applying sufficient energy to the layer of polymer at the first via location through the insulating layer to ablate the insulating layer and to form a first via as mass of graphite that extends into electrical contact with the first electrode and is surrounded by the insulating layer in a plane of the insulating layer.

Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.

Abstract: Provided herein are methods of forming a coating film that include providing a coating source including an orthorhombic vernier phase rare-earth element oxyfluoride and a part in a vacuum chamber, and performing a physical vapor deposition (PVD) process to form the coating film the part, wherein the coating film includes the orthorhombic vernier phase rare-earth element oxyfluoride. Apparatus including parts having coating films comprising an orthorhombic vernier phase rare-earth element oxyfluoride are also provided.

Abstract: Disclosure relates to an electrochemical membrane degassing apparatus including a liquid channel in which raw water flows, a gaseous channel in which gas degassed from the raw water flows, a gas separation membrane allowing gas in the raw water to be moved to the gaseous channel, a surface modification layer formed at the gas separation membrane, and a power supply unit applying power to the surface modification layer, and selectively operated in either of a first process mode applying a low voltage power and a second process mode applying a high voltage power, wherein in the first process mode, an electrostatic repulsive force is generated between the surface modification layer and organic particles, and in the second process mode, a radical is generated, and the organic particles is oxidized by the radical. Accordingly, the efficiency of membrane degassing can be improved and membrane contamination can be prevented.

Abstract: In one aspect, the present invention provides recombinant polynucleotides. In some embodiments, the recombinant polynucleotides comprise a cytomegalovirus (CMV) genome, or a portion thereof, and a nucleic acid sequence encoding an antigen, wherein the CMV genome or portion thereof comprises a mutation within a interleukin-10-like gene sequence. Methods for preventing and treating diseases such as infectious diseases and cancer are also provided herein.

Abstract: An electroluminescent layer according to the present invention comprises a core-shell particle comprising a perovskite crystal core and a shell of a dielectric polymer, wherein a charge transfer pathway to the perovskite crystal core is formed by dielectric breakdown of the dielectric polymer. The electroluminescent layer according to the present invention can prevent the deterioration of perovskite crystals due to external moisture, oxygen, or the like since the perovskite crystal core is enclosed and protected by the dielectric polymer and can have improved charge transfer and injection efficiencies since charges are directly transferred and injected to the perovskite crystals through the charge transfer pathway formed by dielectric breakdown of the dielectric polymer.

Abstract: A method for determining whether a Systemic lupus erythematosus (SLE) patient is undergoing a pre-flare event, the method comprising obtaining a blood, serum, plasma, or saliva sample from the SLE patient; assessing a level of expression for each of a plurality of biomarkers, the plurality of biomarkers comprising OPN, MCP-1/CCL2, MCP-3/CCL7, IL-17A, TNFRII, TNFRI, IL-4, IL-5, BLyS, TNF?, and IL-7; determining a Lupus Flare Risk Prediction Index (LFPI) for the patient based upon the level of expression for each of a plurality of biomarkers; and based upon the LFPI, determining whether the patient is undergoing a pre-flare event.

Abstract: Provided are probiotic bacterium-derived extracellular micro- and/or nanoparticles.

Abstract: Methods for determining a variant frequency in a test sample from a subject, and methods for labeling sequencing reads as having or not having a variant are described herein. Exemplary methods include generating a reference match score and a variant match score by aligning sequencing reads to a corresponding variant sequence and a corresponding reference sequence, and labeling the sequencing read as having or not having the variant based on the determined match scores. Also described herein are methods monitoring disease progression and methods of treating a subject having a disease. Further described are devices and systems for implementing such methods.

Abstract: A method of treating a subject suffering from an ischemic disease associated with Ca2+ overload is provided, the method including administering to the subject an effective amount of an inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase. Also provided is a method of treating a subject suffering from acute ischemic stroke, the method including administering to the subject an effective amount of the ATR kinase inhibitor berzosertib.

Abstract: Disclosure relates to an electrochemical lithium recovery system, and the electrochemical lithium recovery system is characterized by having a first flow electrode module that selectively extracts lithium ions from an object solution containing a waste battery active material by electrical attraction, and a second flow electrode module recovering the lithium ions extracted by the first flow electrode module, by the electric repulsive force. Accordingly, the electrochemical lithium recovery system does not require a high temperature treatment process, does not require a large amount of chemicals, and can ensure high recovery efficiency.

Abstract: Compositions and methods for modifying the production levels of alkaloids in plants are provided. Alkaloid production can be genetically controlled by modulating the transcriptional activation of PMT genes mediated by members of the ERF family and/or Myc family of transcription factors. Novel nucleotide sequences encoding the Myc family of transcription factors are also provided.

Abstract: Disclosed are a music data analysis apparatus capable of analyzing and visualizing creation principles of music and a music data generation apparatus capable of using the creation principles. The music data generation apparatus may comprise: a memory; and a processor executing at least one instruction stored in the memory, wherein the processor is configured to perform: generating a seed overlap matrix so that the seed overlap matrix represents musical features of seed music data; and generating new music data based on the seed overlap matrix.