Abstract: An IL-8 receptor (e.g., CXCR1 or CXCR2) modified CAR T cell is provided, as well as a nucleic acid encoding the IL-8 modified CAR T cell and method of use.
Type:
Grant
Filed:
September 6, 2018
Date of Patent:
October 17, 2023
Assignee:
University of Florida Research Foundation, Inc.
Abstract: The present invention relates to a nano-ligand for promoting cell adhesion and differentiation of stem cells and a method of promoting cell adhesion and differentiation of stem cells by using the nano-ligand, and the method of promoting cell adhesion and differentiation of stem cells according to the present invention may temporally and spatially, and reversibly control nano-ligand sliding by applying a magnetic field to a substrate including the nano-ligands, and efficiently control stem cell adhesion and differentiation ex vivo or in vivo through the magnetic-field based on spatiotemporal control.
Type:
Application
Filed:
June 21, 2023
Publication date:
October 12, 2023
Applicant:
Korea University Research and Business Foundation
Abstract: A hydrogel coating composition for a chemical sensor includes a photo-crosslinkable monomer containing a cationic functional group; a pH indicator dye; a viscosity modifier; and a solvent. The hydrogel coating composition for a chemical sensor can be used for identifying freshness of foods by detecting volatile basic nitrogen or toxic chemicals generated when food spoils, such as ammonia, hydrogen sulfide, etc., and can be coated in desired patterns on a substrate. A chemical sensor fabricated from the hydrogel coating composition is designed to fix a pH indicator dye through an ionic bond to prevent the detachment of the indicator dye. Therefore, the chemical sensor exhibits excellent color reproducibility and has stability as a sensor.
Type:
Application
Filed:
June 21, 2021
Publication date:
October 12, 2023
Applicant:
Kookmin University Industry Academy Cooperation Foundation
Inventors:
Hyunjung LEE, Mi Rim HAM, Hyunji KIM, Soohyun KIM
Abstract: Disclosed is a composition for anti-aging or skin regeneration comprising Okanin, and use of Okanin or a salt thereof and, more particularly, to a composition for anti-aging or skin regeneration comprising Okanin represented by the following formula (1) or a salt thereof, and use of Okanin or a salt thereof.
Type:
Application
Filed:
August 27, 2021
Publication date:
October 12, 2023
Applicants:
POSCO CO., LTD, POSTECH Research and Business Development Foundation, RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY
Inventors:
Kyong-Tai KIM, Kwang-Ho KWON, Sung-Wook KIM, Sung-Woo JEONG
Abstract: Disclosed are a method and device for installing a certificate on the basis of encryption and decryption of a contract certificate private key for an electric vehicle communication controller.
Type:
Application
Filed:
September 7, 2021
Publication date:
October 12, 2023
Applicants:
Myongji University Industry and Academia Cooperation Foundation, HYUNDAI MOTOR COMPANY, KIA CORPORATION
Abstract: There is provided a substrate processing method. The method includes providing a substrate having a first surface area and a second surface area having a different surface state than that of the first surface area, exposing the substrate to a substrate surface treatment composition containing a deposition inhibitor, and exposing the substrate to a post-treatment composition containing HF.
Type:
Application
Filed:
February 24, 2023
Publication date:
October 12, 2023
Applicants:
SK Specialty Co., Ltd., Industry-University Cooperation Foundation Hanyang University ERICA Campus
Inventors:
SungWoong CHUNG, Junghun KAWK, Jihun LEE, Woohee KIM, Jeongmin LEE, Seohyun LEE
Abstract: Exemplary embodiments of the present disclosure include systems and methods for treatment of occlusions, including coronary artery chronic total occlusions.
Type:
Application
Filed:
November 28, 2022
Publication date:
October 12, 2023
Applicant:
Research Development Foundation
Inventors:
Marc D. FELDMAN, Thomas E. MILNER, Nitesh KATTA, Arnold ESTRADA, Meagan OGLESBY, Andrew Giles CABE, Mehmet CILINGIROGLU
Abstract: Disclosed is a composition for anti-aging or skin regeneration comprising Isoprocurcumenol, and use of Isoprocurcumenol or a salt thereof and, more particularly, to a composition for anti-aging or skin regeneration comprising Isoprocurcumenol represented by the following formula (1) or a salt thereof, and use of Isoprocurcumenol or a salt thereof.
Type:
Application
Filed:
August 27, 2021
Publication date:
October 12, 2023
Applicants:
POSCO CO., LTD, POSTECH Research and Business Development Foundation, RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY
Inventors:
Kyong-Tai KIM, Kwang-Ho KWON, Sung-Wook KIM, Sung-Woo JEONG
Abstract: A method of making alkenes and/or epoxides from alkanes and hydroxy-alkanes, respectively. In a reactor having an anode and a cathode separated by an ion exchange membrane, and containing a solution comprising water, halogen ions, and an alkane and/or a hydroxy-alkane, apply a potential across the anode and the cathode such that a halogenated intermediate is produced at the anode as an anolyte and hydroxyl ions are produced at the cathode as a catholyte; and combining the anolyte and the catholyte to yield an alkene and/or an epoxide.
Abstract: A metal alloy is provided which includes by weight percentage of the metal alloy, 28 to 55 percent copper, 45 to 63 percent nickel, and 4 to 10 percent iron. The metal alloy may be weight percentage 28 percent copper, 62 percent nickel, and 10 percent iron. The metal alloy may be formed into a foil which may have a thickness of 100 ?m or less or 50 ?m or less. A magnetic field instrument may include a magnetometer core body formed from one or more layers of the foil. The magnetometer core body may be a ring core or a racetrack core. The magnetic field instrument may further include a sense winding and may further include a drive winding. The magnetic field instrument may be a fluxgate magnetometer.
Type:
Application
Filed:
March 21, 2022
Publication date:
October 12, 2023
Applicants:
University of Iowa Research Foundation, The University of British Columbia
Abstract: The invention provides American chestnut leaf compositions comprising oxalate oxidase. The compositions reduce oxalate levels in dietary sources of oxalate and are useful in reducing oxalate levels and reducing stone disease in patients. The invention provides methods of extracting and purifying oxalate oxidase from American chestnut leaf. The invention provides methods of extracting oxalate from biological samples.
Type:
Application
Filed:
March 16, 2023
Publication date:
October 12, 2023
Applicants:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, The Research Foundation for The State University of New York (RFSUNY)
Inventors:
Paul R. Dominguez-Gutierrez, William L. Donelan, Tania Quesada, William A. Powell
Abstract: The present disclosure featured compositions and methods related to the detection and molecular profiling of extracellular vesicles using optical probes, dual imaging approaches, and computationally programing-based image analysis methods. These compositions and methods leverage the unique optoelectrical properties of quantum dots, fluorescently labeled nanoparticles, and gold nanoparticles, which allow reliable, real-time detection of extracellular vesicles and vesicle surface bound or lumenal molecules at single vesicle level.
Type:
Application
Filed:
April 10, 2023
Publication date:
October 12, 2023
Applicant:
The University of Memphis Research Foundation
Inventors:
Xiaohua HUANG, Thang Ba HOANG, Yongmei WANG, Caleb Edward GALLOPS
Abstract: The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.
Type:
Grant
Filed:
July 19, 2019
Date of Patent:
October 10, 2023
Assignee:
Colorado State University Research Foundation
Abstract: Described are polypeptide analogs of parathyroid hormone (PTH) that include an unnatural amino acid substitution at positions 7 or 8 from the N-terminus of the polypeptide. Also described are pharmaceutical compositions useful for treating hypoparathyroidism that contain the analogs and methods of using the analogs to treat hypoparathyroidism.
Type:
Grant
Filed:
September 24, 2020
Date of Patent:
October 10, 2023
Assignees:
Wisconsin Alumni Research Foundation, The General Hospital Corporation
Inventors:
Samuel H. Gellman, Shi Liu, Thomas J. Gardella
Abstract: An aluminum alloy material according to an embodiment of the present invention is an aluminum alloy including a grain boundary and a plurality of grains divided by the grain boundary, and having a face-centered cubic crystal structure, and includes a band formed by employing one or more non-metallic elements selected from oxygen (O), carbon (C) and nitrogen (N) in an aluminum matrix. Each of the grains includes a plurality of sub-grains divided by a low-angle grain boundary (LAGB), and a band positioned at the low-angle grain boundary may form a coherent interface with an aluminum matrix. Since a plurality of dislocations already are present in the band, a dislocation cell size is reduced during plastic deformation, which greatly contributes to an improvement in elongation. Such an aluminum alloy material can be subjected to cold rolling at a high reduction rate, and as a result, a plate having significantly improved elongation can be obtained.
Type:
Grant
Filed:
December 21, 2022
Date of Patent:
October 10, 2023
Assignee:
UIF (University Industry Foundation), Yonsei University
Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.
Type:
Grant
Filed:
September 22, 2021
Date of Patent:
October 10, 2023
Assignees:
North Carolina State University, University of Kentucky Research Foundation
Inventors:
Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano
Abstract: SphericRTC provides real-time 360-degree video communication, which allows the viewer to observe the environment in any direction from the camera location. This more allows users to more-efficiently exchange information and can be beneficial in the real-time setting. The system selects representations of 360-degree frames to allow efficient, content-adaptive delivery. The system performs joint content and bitrate adaptation in real-time by offloading expensive transformation operations to a GPU. The system demonstrates that the multiple sub-components: viewport feedback, representation selection, and joint content and bitrate adaptation, can be effectively integrated within a single framework. Compared to a baseline implementation, views in SphericRTC have consistently higher visual quality. The median Viewport-PSNR of such views is 2.25 dB higher than views in the baseline system.
Type:
Grant
Filed:
October 4, 2021
Date of Patent:
October 10, 2023
Assignee:
The Research Foundation for The State University of New York
Abstract: A video decoding apparatus is provided for decoding pictures using inter-prediction. The video decoding apparatus includes a predictor that generates affine prediction samples for respective subblocks in a target block in a current picture to be decoded by performing affine motion prediction on a subblock-by-subblock basis using control point motion vectors which respectively correspond to corners of the target block. The predictor also modifies sample values of the affine prediction samples by executing a first coding tool, the first coding tool compensating for motion according to sample positions in each of the subblocks using the control point motion vectors.
Type:
Grant
Filed:
July 20, 2022
Date of Patent:
October 10, 2023
Assignees:
Hyundai Motor Company, Kia Corporation, Ewha University-Industry Collaboration Foundation
Inventors:
Je Won Kang, Seung Wook Park, Wha Pyeong Lim
Abstract: Disclosed is a highly reliable physically unclonable function technology. In a tunneling-based memory device disclosed herein, a conductive layer (e.g., Al2O3) is stacked on a bottom electrode, an oxide layer (e.g., TiOx) is stacked on the conductive layer, and a top electrode is stacked on the oxide layer. The tunneling-based memory device has a structure of a memristor crossbar array and has a current-voltage characteristic independent of a temperature that is an external environmental variable due to a tunneling mechanism when constructing an unpredictable physically unclonable function (PUF) of hardware as a memory semiconductor array.
Type:
Grant
Filed:
April 19, 2023
Date of Patent:
October 10, 2023
Assignee:
Inha University Research and Business Foundation