Abstract: This present patent application relates to a method for controlling a targeted gene expression with an environmental trigger useful for manufacturing a natural product or an analogue thereof biologically. In particular, the present invention discloses an expression system comprises a gene expressing for a fusion protein of elastin-like polypeptides (ELPs) and a transcription factor, wherein a targeted gene expression is regulated by the phase change of the fusion protein initiated by an environmental trigger, including changes of temperature, pH value, ionic strength or a combination thereof. The method, the expression system and their products are within the scope of this invention.

Abstract: Herein provided is a new runner-type peanut variety designated ‘Georgia-18RU’ as well as the seeds, plants and derivatives of the new peanut variety ‘Georgia-18RU’. Also provided are tissue cultures of the new peanut variety ‘Georgia-18RU’ and the plants regenerated therefrom. Methods for producing peanut plants by crossing the new peanut variety ‘Georgia-18RU’ with itself or another peanut variety (such as another runner-type peanut variety) and plants produced by such methods are also provided. ‘Georgia-18RU’ is a unique runner-type peanut cultivar having a combination of high level of tomato spotted wilt virus (TSWV) resistance and leaf scorch resistance caused by Leptosphaerulina crassiasca (Séchet) Jackson and Bell, and high yield. ‘Georgia-18RU’ provides a medium maturity runner-type peanut cultivar with a prominent main stem, medium green foliage, medium-large runner seed size, and pink seedcoat color.

Abstract: A solid multiphase polymer blend material comprising: (i) a polyphenolic substance having a molecular weight of at least 500 g/mol; and (ii) a polyester having a molecular weight of at least 500 g/mol; wherein at least a portion of the polyphenolic substance is covalently bonded directly or through a linking moiety to the polyester. Methods for producing the blend material are also described, e.g., homogeneously melt blending a mixture comprising components (i) and (ii) under conditions resulting in covalent attachment of at least a portion of the polyphenolic substance directly or through a linking moiety to the polyester. Methods for producing objects made of the blend material by melt extrusion are also described.

Abstract: The present invention discloses mass spectrometry (MS)-based methods and tagging reagents for qualitative and quantitative analysis of post-translational modified (PTM) proteins in biological and clinical samples. The present invention utilizes thiol-containing tagging reagents which are able to bind to or derivatize biomolecules, preferably post-translational modified (PTM) polypeptides such as citrullinated and homocitrullinated polypeptides. The tagging reagents are preferably biotin-derived tags able to react with a side chain of the modified polypeptides.

Abstract: The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)

Abstract: The present application relates generally to a process of manufacturing a plurality of products from chia seeds. The process comprises socking chia seeds in a large volume of water for a period of time followed by sonication at an elevated temperature to remove the soluble fiber, the mucilage of chia seeds using vacuum filtration. The oil component is extracted from mucilage removed chia seeds and the leftover is hydrolyzed in presence of an enzyme to afford a product of protein hydrolysates and a product of insoluble fiber of chia seeds. Both the process and the products are within the scope of this application.

Abstract: Provided is a holographic display apparatus capable of providing an expanded viewing window when reproducing a holographic image via an off-axis technique. The holographic display apparatus includes a spatial light modulator comprising a plurality of pixels arranged two-dimensionally; and an aperture enlargement film configured to enlarge a beam diameter of a light beam coming from each of the plurality of pixels of the spatial light modulator. The beam diameter of each light beam enlarged by the aperture enlargement film may be greater than the width of an aperture of each pixel of the spatial light modulator.

Abstract: A user interface system and an operation method therefor are disclosed. The user interface system includes an electroencephalogram (EEG) detection device that detects event-related potential information by measuring an EEG of a user and includes a user input recognition device that recognizes and corrects an input recognition error by analyzing the event-related potential information when the user's input is recognized.

Abstract: A field-enhancing device includes at least one metal layer or a metal grating consisting of metal stripes or a dielectric grating. Usually the device is constructed on some substrate. The adhesive layer is advantageous when the next layer is metallic but is not needed with dielectric layers. The next layers to be constructed form a mirror structure that can also be omitted for simple field-enhancing device constructs. The mirror structure can be either a metal mirror structure or a distributed Bragg reflector structure (DBR). The next layer is the thin metal layer. This layer can be covered with a 1-D metal grating consisting of metal stripes or with a dielectric grating having similar geometry. The structure can also be fabricated without metals when dielectric grating is used as the field-enhancing part. Finally, a protective layer can be added on top of the structure.

Abstract: Disclosed are a memory device based on an IGO channel layer and a method of fabricating the same. More particularly, the memory device according to an embodiment includes multilayers including at least one transition metal; and a channel layer formed adjacent to the multilayers and configured to include an indium gallium oxide (IGO) material.

Abstract: A row hammer prevention circuit for providing a reference address to perform an additional refresh operation includes a history storage circuit configured to store one or more first addresses, each of the first addresses having been provided as the reference address. The row hammer prevention circuit further includes an address storage circuit configured to store a row address corresponding to an active command, a reference address storage circuit configured to store one or more second addresses, and a control circuit configured to provide the reference address in response to a refresh command.

Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.

Abstract: An image encoding/decoding method and apparatus are provided. An image decoding method performed by an image decoding apparatus according to the present invention may comprise deriving an intra-prediction mode of a current block, and performing intra-prediction for the current block based on the intra-prediction mode. The deriving of the intra-prediction mode may comprise decoding a predetermined mode sameness indicator.

Abstract: Bioreactors and components of bioreactors are described as may be beneficially utilized in development and conditioning of cellular materials for study or implant. The bioreactors are modular and components of the bioreactors can be easily assembled with alternatives provided to develop specific, predetermined conditioning environments for cellular materials (e.g., implantable tissue). By selection of one of multiple alternative compliance chambers, a bioreactor can be utilized to condition tissue in a low pressure circuit (e.g., a pulmonary heart circuit), and by utilization of an alternative compliance chamber, the bioreactor can instead condition tissue in a high pressure circuit (e.g., an aortic heart circuit).

Abstract: The invention generally relates to a purified inactivated Zika virus (ZIKV), methods for producing the purified inactivated ZIKV, immunogenic compositions and vaccines comprising the purified inactivated ZIKV and methods for the prevention and/or treatment of infection by ZIKV.

Abstract: This document provides methods and materials related to treating cancer. For example, methods and materials for using particles (e.g., nanoparticles) containing (a) one or more molecules having the ability to bind to a cancer cell (e.g., a human breast cancer cell) and (b) one or more molecules having the ability to bind to an APC (e.g., a human macrophage) to treat cancer are provided.

Abstract: A low-power transmission system for periodically transmitted data communicates the periodic data as an interval between two transmitted anchor symbols when the transmitter and associated circuitry are shut down. Meaningful power savings for short data words is obtained by use of a star topology allowing elimination of the receiver power consumption. Multi-bit anchor symbols provide improved error detection and the separation of simultaneous transmission from multiple transmitters by a single receiver.

Abstract: A method of preparing hydrophobic porous silica includes reacting a porous silica particle containing a hydrophilic group in a solvent with an organosilane compound under a basic catalyst to form a mixture, drying the mixture comprising the porous silica particle in a vacuum, and condensation reacting the hydrophilic group of the porous silica particle with the organosilane compound on the surface of the porous silica particle to modify the surface of the porous silica particle to be hydrophobic.

Abstract: Disclosed herein are methods and compositions for identifying and/or treating subjects having or likely to have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD). Antibodies specific for one or more di-amino acid repeat-containing proteins are also provided herein.

Abstract: A method of performing an endoscopic submucosal resection includes using two magnet-attached hemostatic clips that are selectively coupled to one another via their respective magnets.