Abstract: Aspects of the present disclosure are directed to a three-dimensional joint and/or formation thereof, such as by 3D-printing the joint. The joint is provided with an interface region having a curable material in a curable state. The joint is positioned with the interface region in contact with a joinable member, and the interface region is cured to form a bond between the joint and the joinable member. Such an approach may, for example, involve forming a mechanical and/or chemical bond with the joint. Further, by utilizing such a joint (e.g., in a 3D-printed form), complex structural components can be formed from a curable material that can be partially cured with structures formed therein, and cured further to create the bond.

Abstract: A method of switching a phase-change device (Device), including changing phase of the Device from a semiconducting 2H phase to a new 2Hd phase with a higher conductivity, the Device having an active material with a thickness including a phase transition material to thereby transition the Device from a high resistive state (HRS) to a low resistive state (LRS) by application of a set voltage and further to return the Device from the LRS back to the HRS by application of a reset voltage.

Abstract: The invention generally provides systems and methods for producing a chemical product. In certain embodiments, the invention provides systems that include a chemical product production unit. The chemical production unit includes a plurality of microfluidic modules configured to be fluidically coupled to each other in an arrangement that produces a chemical product from an input of a plurality of starting reagents that react with each other due to conditions within the plurality of microfluidic modules through which the starting reagents flow. The system also includes a droplet dispenser fluidically coupled to the chemical product production unit that forms and dispenses droplets of the chemical product.

Abstract: This invention generally relates to a method for preparing and transferring a monolayer or thin film. In particular this present invention is an improved version of the Langmuir-Schaefer technique for preparing and transferring a monolayer or thin film, incorporating in situ thermal control of the substrate during the transfer process.

Abstract: A computer-implemented process is disclosed for generating a labeled overhead image of a geographical area. A plurality of ground level images of the geographical area is retrieved. A ground level feature map is generated, via a ground level convolutional neural network, based on features extracted from the plurality of ground level images. An overhead image of the geographical area is also retrieved. A joint feature map is generated, via an overhead convolutional neural network based on the ground level feature map and features extracted from the plurality of ground level images. Geospatial function values at a plurality of pixels of the overhead image are estimated based on at least the joint feature map and the overhead image. The plurality of pixels of the overhead image is labeled according to the estimated geospatial function values.

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

Abstract: A home medication management system and method are provided comprise a home medication management device, a computing device associated with a user of medication management system, and a server in communication with the home medication management device and the computing device. The server comprises memory storing an application program interface (API) that is configured to manage the home medication of a patient including the registration of prescriptions, transmission of the registered prescriptions to the home medication management device, association of medications of the registered prescriptions with recesses of the home medication management device, presentation of alerts to the patient at scheduled times to take the medications based on the prescriptions, monitoring the patient for compliance with the alerts, determining whether the patient has taken the medication as scheduled, and presenting the determination to the user via the computing device.

Abstract: Disclosed herein are a method of fabricating a stretchable electrical circuit and an apparatus for fabricating a stretchable electrical circuit, wherein the method of fabricating a stretchable electrical circuit includes stretching a stretchable substrate, forming a plurality of alignment marks on a surface of the stretchable substrate, forming a first axis extending from a line connecting two alignment marks among the plurality of alignment marks, and a second axis perpendicular to the first axis, marking one point of the surface of the stretched stretchable substrate with coordinates made by the first axis and the second axis, and disposing electrical components using the coordinates.

Abstract: Disclosed herein are methods and materials for improving brain function and/or promoting neurogenesis m a patient suffering from impaired brain function. Specifically exemplified herein ls the co-administration of phenserine and NBI-18. A method of treating a neurodegenerative disease in a patient in need thereof, said method comprising co-administering to the patient phenserine, or pharmaceutically acceptable salt thereof, and NBI-18, or pharmaceutically acceptable salt thereof, in respective amounts and frequency such that they work together to improve brain function or induce neurogenesis in the patient.

Abstract: A high temperature piezoelectric sensor device such as a high temperature accelerometer, force sensor, pressure sensor, temperature sensor, acoustic sensor and/or acoustic transducer for use at temperatures up to 1000° C. The high temperature device includes a base, a piezoelectric element attached to the base and a pair of electrodes in electrical communication with the piezoelectric element. The piezoelectric element can have a d15 piezoelectric coefficient between 16.0-18.0 pC/N for all temperatures between 25 to 700° C., and a rotated d33 piezoelectric coefficient of 8.0-9.5 pC/N with zero face shear/thickness shear piezoelectric coefficients d34. d35 and d36 in the same temperature range. The piezoelectric element can also have an electromechanical coupling factor k15 variation of less than 7%, and d15 and rotated d33 piezoelectric coefficient variations of less than 5% for temperatures between 25 to 700° C.

Abstract: Provided is an electrode active material slurry including a clustered complex and a slurry, wherein the clustered complex includes an electrode active material, a solid electrolyte, a conductive material, and a first binder, and the slurry includes a solvent and a second binder. The electrode active material slurry may include the clustered complex including the first binder and the slurry including the second binder so as to decrease a surface area of the overall complex, such that adhesion property with the current collector may be sufficiently secured even by using a small amount of binder, and performance of the all-solid secondary battery may be further improved.

Abstract: According to the present invention, there is provided a method of decoding a video signal, the method including: determining an intra prediction mode of a current block; applying a filter to a first reference sample adjacent to the current block; obtaining a first prediction sample of the current block on the basis of the intra prediction mode and a second reference sample obtained by applying the filter; and obtaining a second prediction sample of the current block using the first prediction sample and the first reference sample.

Abstract: Attenuated vaccines to protect vertebrate animals and people against tick-born rickettsial, Ehrlichia and Anaplasma species infections is disclosed. Also disclosed are methods to modify the organism to achieve the desired immunity through the modification of a novel genetic region involved in pathogenesis. These compounds represent a needed vaccine against an organism causing life-threatening febrile illness in humans and animals, and also represent the potential to develop new classes of drugs targeting the gene products of genes Ech_0379 and Ech_0230, and their homologs of other related rickettsial pathogens.

Abstract: A device for producing a subwavelength hologram. The device comprises a metasurface layer attached to a substrate. The metasurface layer includes an array of plasmonic antennas that simultaneously encode both wavelength and phase information of light directed through the array to produce a hologram. The wavelength is determined by the size of the antennas, and the phase is determined by the orientation of the antennas.

Abstract: Systems and methods suitable for capable of autonomous crack detection in surfaces by analyzing video of the surface. The systems and methods include the capability to produce a video of the surfaces, the capability to analyze individual frames of the video to obtain surface texture feature data for areas of the surfaces depicted in each of the individual frames, the capability to analyze the surface texture feature data to detect surface texture features in the areas of the surfaces depicted in each of the individual frames, the capability of tracking the motion of the detected surface texture features in the individual frames to produce tracking data, and the capability of using the tracking data to filter non-crack surface texture features from the detected surface texture features in the individual frames.

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

Abstract: A continuous dynamic positron emission tomography (PET) assembly for imaging a target region of a subject. The assembly includes a radioactive tracer isotope injector configured to administer a radioactive isotope into the subject and a scintillator crystal configured to absorb ionizing radiation from the subject and emit scintillator light. The scintillator crystal undertakes the absorption substantially at the same time of the start of administering the radioactive isotope. The assembly also includes a photo detector in communication with the scintillator crystal, wherein the photodetector is configured to detect the emitted scintillation light as input and provide electrical signals as output. The assembly further includes a signal digitizing circuitry converting the output electrical signals into digital data. Moreover, the assembly includes a processor configured to receive the digital data and implement a model to convert the digital data into a three dimensional, tomographic image reconstruction.

Abstract: The present invention provides a pharmaceutical composition comprising mesenchymal stem cells, a hyaluronan and a pharmaceutically acceptable carrier. The pharmaceutical composition is used for the treatment of the joint disease. The mesenchymal stem cells in the composition are at least one selected from the group consisting of infra-patellar fat pad stromal cells, bone marrow stem cells, Wharton's jelly stem cells and adipose derived stem cells. The concentration of the hyaluronan is in a range from 25% (v/v) to 75% (v/v). The present invention further provides a method for treating a joint disease, comprising a step of administrating a composition containing mesenchymal stem cells, a hyaluronan and a pharmaceutically acceptable carrier to an injured joint tissue of a subject.

Abstract: There is provided a fluid analysis chamber module that allows an analysis element to be replaced in a sliding manner. The module includes a middle body, an upper body, and a lower body, in which the upper body and the lower body are rotated to be in contact with an upper surface and a lower surface of the middle body and to release from the contact state. The middle body provides a chamber hole where a tray with the analysis element seated thereon can be mounted. The middle body is provided on its front end with a tray receiving opening through which the tray is mounted into the chamber hole. When the upper body and lower body are rotated to be in contact with the upper surface and the lower surface, respectively, the chamber hole is closed, a fluid supplying line and discharging line are sealed, pogo pins for power supply and signal transmission are contacted to electrodes of the analysis element.