Abstract: The invention relates to a method for photoreleasing a moiety G from a compound of the formula A-G. The methods of the present invention comprise irradiating a composition comprising the compound of the formula A-G at a wavelength of >500 nm, so as to photorelease the moiety G from the moiety A; wherein the moiety A comprises a chromophore and the moiety G comprises an organic compound.
Type:
Grant
Filed:
September 24, 2018
Date of Patent:
December 3, 2019
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: A method includes receiving multiple compound muscle action potential values (CMAPs), wherein each CMAP is an onset latency, a peak latency, a conduction velocity, or a response amplitude measured from a baseline; for each of the CMAPs and for each of a number parameters calculated from the CMAPs, determining a corresponding demyelinating boundary value using a normal value from a preselected population; determining whether each of the CMAPs and each of the parameters exceeds the corresponding demyelinating boundary value; determining one or more demyelinated nerve pathways based on which of the CMAPs and the parameters exceeds the corresponding demyelinating boundary value; indicating on a display which of the CMAPs and the parameters exceed the corresponding demyelinating boundary value; and displaying, in pictorial form, an anatomical diagram indicating the demyelinated nerve pathways.
Type:
Grant
Filed:
November 4, 2014
Date of Patent:
December 3, 2019
Assignee:
The Research Foundation of State University of New York
Inventors:
Paul Jacob Maccabee, Lawrence Philip Eberle
Abstract: Biodegradable composite membranes with antimicrobial properties consisting of nanocellulose fibrils, chitosan, and S-Nitroso-N-acetylpenicillamine (SNAP) were developed and tested for food packaging applications. Nitric oxide donor, SNAP was encapsulated into completely dispersed chitosan in 100 mL, 0.1N acetic acid and was thoroughly mixed with nanocellulose fibrils (CNF) to produce a composite membrane. The fabricated membranes had a uniform dispersion of chitosan and SNAP within the nanocellulose fibrils, which was confirmed through Scanning Electron Microscopy (SEM) micrographs and chemiluminescence nitric oxide analyzer. The membranes prepared without SNAP showed lower water vapor permeability than that of the membranes with SNAP. The addition of SNAP resulted in a decrease in the Young's modulus for both 2-layer and 3-layer membrane configurations.
Type:
Grant
Filed:
May 15, 2017
Date of Patent:
December 3, 2019
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Ib? having a combination of G233V, D235Y and M239V mutations and an agent to detect a complex between the recombinant glycoprotein Ib? and von Willebrand factor.
Type:
Grant
Filed:
May 15, 2017
Date of Patent:
December 3, 2019
Assignees:
Versiti Blood Research Institute Foundation, Inc., The Medical College of Wisconsin, Inc.
Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
Type:
Grant
Filed:
September 16, 2016
Date of Patent:
December 3, 2019
Assignees:
Curza Global, LLC, University of Utag Research Foundation
Inventors:
Ryan E. Looper, Rachel M. Vaden, Joseph B. Gibbons, Justin M. Salvant, Anne V. Edwards, Matthew S. Sigman, Bryan E. Welm
Abstract: The present invention relates to a method for detecting renal disease and for assessing the efficacy of dialysis treatment using imaging agents having desirable in vivo properties.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
December 3, 2019
Assignees:
Beth Israel Deaconess Medical Center, Georgia State University Research Foundation Inc.
Abstract: A memory system comprising a plurality of layers of spaced-apart row electrodes, each having a dorsal and a ventral side, a plurality of layers of spaced-apart column electrodes, each having a dorsal and a ventral side is, and a plurality of layers of spaced-apart memristors arranged so that each of the row electrodes and each of the column electrodes is in contact with at least one memristor on the dorsal side thereof and with at least one memristor on the ventral side thereof.
Abstract: An automated percentage of breast density measure (PDa) that analyzes signal dependent noise (SDN) based on a wavelet expansion using full field digital mammography (FFDM). A matched case-control dataset is used with images acquired from a specific direct x-ray capture FFDM system. PDa is applied to the raw and clinical display representation images. Transforming (pixel mapping) of the raw image to another representation (raw-transformed) is performed using differential evolution optimization and investigated the influence of lowering the native spatial resolution of the image by a one-half. When controlling for body mass index, the quartile specific ORs for the associations of PDa with breast cancer varied with representation and resolution. PDa is a valid automated breast density measurement for a specific FFDM technology and compares well against PD (operator-assisted or the standard) when applied to either the raw-transformed or clinical display images from this FFDM technology.
Type:
Grant
Filed:
May 24, 2018
Date of Patent:
December 3, 2019
Assignees:
H. Lee Moffitt Cancer Center & Research Institute, Inc., Mayo Foundation for Medical Education and Research
Inventors:
John J. Heine, Thomas A. Sellers, Celine M. Vachon, Erin E. Fowler
Abstract: The two-dimensional metal carbide desalination membrane includes a stack of two-dimensional metal carbide layers. A two-dimensional metal carbide included in the two-dimensional metal carbide layers may have the formula Ti3C2Tx, where T represents a terminating functional group, and x represents a number of the terminating functional groups. The terminating group may be oxygen, hydroxide (OH), fluorine or combinations thereof. The two-dimensional metal carbide desalination membrane includes nano-channels which are selectively permeable to ions. The two-dimensional metal carbide desalination membrane is selectivity permeable to a number of different cations, including Li+, Na+, K+, Mg2+, Ca2+, Ni2+ and Al3+, with counter Cl? anions. Permeation rates depend on the charges of the cations and the ions' hydrated radius, with a critical point around 4.0 ?. The two-dimensional metal carbide desalination membranes can be used as desalination and/or water filtration membranes.
Type:
Grant
Filed:
November 17, 2015
Date of Patent:
December 3, 2019
Assignee:
Qatar Foundation for Education, Science and Community Development
Inventors:
Khaled Ahmed Mahmoud, Yury Gogotsi, Chang Evelyn Ren
Abstract: Apparatus for transmitting media content in multimedia streaming system is provided. Apparatus includes a transceiver configured to receive a request for the media content; and transmit a plurality of segments regarding the media content, wherein the plurality of segments comprises an initialization segment (IS) and a media segment (MS), wherein the IS includes a moov box and a stsd box, wherein the stsd box includes sample description entries required to decode all representations within a representation group, and wherein each sample description entry in the stsd box corresponds to coding information of a media component in each of the representations, wherein the MS includes a moof box including a sample description index and a mdat box including media data, and wherein a value of the sample description index is an index of one of the sample description entries in the stsd box.
Type:
Grant
Filed:
November 27, 2018
Date of Patent:
December 3, 2019
Assignees:
Samsung Electronics Co., Ltd, University of Seoul Industry Cooperation Foundation
Inventors:
Sung-Ryeul Rhyu, Yong-Han Kim, Seo-Young Hwang
Abstract: A spintronic memory device having a spin momentum-locking (SML) channel, a nanomagnet structure (NMS) disposed on the SML, and a plurality of normal metal electrodes disposed on the SML. The magnetization orientation of the NMS is controlled by current injection into the SML through normal metal electrode. The magnetization orientation of the NMS is determined by measuring voltages across the NMS and the SML while flowing charge current through the SML via the normal metal electrodes.
Type:
Grant
Filed:
February 13, 2018
Date of Patent:
December 3, 2019
Assignee:
Purdue Research Foundation
Inventors:
Shehrin Sayed, Supriyo Datta, Esteban E. Marinero-Caceres
Abstract: A charging device according to an exemplary embodiment of the present invention may include: a battery adapted and configured to store a DC voltage, first and second motors adapted and configured to operate as a motor or a generator, first and second inverters adapted and configured to operate the first and second motors, a voltage transformer adapted and configured to boost the DC voltage of the battery to supply it to the first and second inverters and boosts the DC voltage of the inverter to supply it to the battery, and a charging controller adapted and configured to operate the first and second inverters as a booster or operate the voltage transformer as a buck booster according to a voltage that is input through a neutral point of the first and second motors and the voltage of the battery.
Type:
Grant
Filed:
August 4, 2017
Date of Patent:
December 3, 2019
Assignees:
Hyndai Motor Company, Research & Business Foundation Sungkyunkwan University, Kia Motors Corporation
Abstract: Disclosed are an apparatus and a method for predicting a fault state of an inverter. The apparatus for predicting a fault state of an inverter includes: an inverter converting DC power into AC power; a switching element provided in the inverter; and a controller extracting a fault sign factor based on an output signal output from the inverter and predicting a fault of the switching element based on the fault sign factor.
Type:
Grant
Filed:
December 19, 2016
Date of Patent:
December 3, 2019
Assignees:
Hyundai Motor Company, Seoul National University R&DB Foundation
Inventors:
Deog Hyeon Kim, Yong Un Cho, Yongchae Lim, Byeng Dong Youn, Hyunseok Oh, Junmin Lee
Abstract: A data encoder including a preprocessor configured to divide a data stream into a plurality of sub data blocks; a plurality of meta data generators each configured to generate meta data from one of the plurality of sub data blocks; and a plurality of data compressors each configured to compress one of the plurality of sub data blocks according to the meta data.
Type:
Grant
Filed:
November 6, 2018
Date of Patent:
December 3, 2019
Assignees:
SK hynix Inc., Seoul National University R&DB Foundation
Inventors:
Jiwoong Choi, Boyeal Kim, Hyun Kim, Hyuk Jae Lee, Junseo Lee, Changmin Kwak, Youngdoo Song
Abstract: A method for transmitting and receiving signals based on a codebook in a multi-antenna wireless communication system, the method comprising: transmitting a channel state information reference signal (CSI-RS); and reporting channel state information to the base station; Wherein the channel state information includes a Precoding Matrix Indicator (PMI) for indicating a specific code vector among a plurality of code vectors included in the codebook, the codebook being included in each code vector And a phase difference between adjacent elements may be set to be different from each other.
Type:
Grant
Filed:
December 29, 2016
Date of Patent:
December 3, 2019
Assignees:
LG Electronics Inc., Sogang University Research Foundation
Inventors:
Jonghyun Park, Junyeub Suh, Junsik Shin, Wonjin Sung, Kijun Kim
Abstract: A catalytic nanoparticle can include a nanodiamond core, a thin-layer polymeric film applied to an outer surface of the nanodiamond core, and a catalyst immobilized at an outer surface of the thin-layer polymeric film. The nanoparticles can also be used in connection with a transducer to form a sensor. A method of catalysis can include contacting the catalytic nanoparticle with a reactant in a reaction area. The reactant can be capable of forming a reaction product via a reaction catalyzed by the catalyst. The method of catalysis can also include facilitating a catalytic interaction between the catalytic nanoparticle and the reactant.
Type:
Grant
Filed:
August 30, 2017
Date of Patent:
December 3, 2019
Assignee:
University of Utah Research Foundation
Inventors:
Jennifer S. Shumaker-Parry, Arthur D. Quast
Abstract: Exemplary embodiments of the present disclosure include a combined catheter-based optical coherence tomography-two-photon luminescence (OCT-TPL) imaging system. Exemplary embodiments further include methods to detect, and further characterize the distribution of cellular components (e.g., macrophage, collagen/elastin fiber, lipid droplet) in thin-cap fibroatheromas with high spatial resolution in vivo.
Type:
Grant
Filed:
September 13, 2016
Date of Patent:
December 3, 2019
Assignee:
Research Development Foundation
Inventors:
Marc Feldman, Thomas Milner, Tianyi Wang, Jennifer Whedbee
Abstract: Provided is a bacterial strain which produces a family of mosquitocidal toxins, Xenorhabdus MT, on deposit with the American Type Culture Collection, PTA-6826, insecticidal compositions comprising the mosquitocidal toxin(s) produced by Xenorhabdus MT, a mosquitocidal toxin preparation prepared from spent culture medium, whole culture or cells or a mixture thereof, of Xenorhabdus MT and method of insect control, especially mosquito control. Also provided are microbial compounds (same as mosquitocidal toxins) compositions comprising them and use in formulating therapeutic and other antimicrobial compositions, and methods of use for inhibiting microbial growth and for treating infection.
Type:
Grant
Filed:
September 28, 2016
Date of Patent:
December 3, 2019
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Jerald Coleman Ensign, Que Lan, David Dyer
Abstract: Disclosed herein are novel motuporamine compounds that act as anti-metastatic agents with low toxicity and high anti-migration activity. The non-toxic, anti-metastatic agents may be given to patients with potential or actual metastatic cancers, such as pancreatic cancers, alone in combination with known and/or new therapies to help block the growth and spread of tumor(s).
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
December 3, 2019
Assignee:
University of Central Florida Research Foundation, Inc.