Abstract: Provided is an apparatus and method for frontal audio rendering in interaction with a screen size, the method including measuring playback environment information used to play back input content; and correcting an audio signal to be output based on the measured playback environment information and production environment information included in the input content.

Abstract: A set of target peptides are presented by HLA class I molecules on the surface of hepatocellular carcinoma (HCC) ceils and/or esophageal cancer cells. They are envisioned to among other things (a) stimulate an immune response to the proliferative disease, e.g., HCC and/or esophageal cancer, (b) function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) facilitate antibody recognition of tumor boundaries in surgical pathology samples, (d) act as biomarkers for early detection and/or diagnosis of the disease, and (e) act as targets in the generation anti-body-like molecules which recognize the target-peptide/MHC complex.

Abstract: A force sensing probe (100) for sensing snap-in and/or pull-off force of a liquid droplet (111) brought into and/or separated from contact with a hydrophobic sample surface (151), respectively, comprises: a sensing tip (101); a sensor element (102) connected to the sensing tip, capable of sensing sub-micronewton forces acting on the sensing tip in a measurement direction; and a droplet holding plate (104) having a first main surface (105) and a hydrophilic second main surface (106) connected via a peripheral edge surface (107), and being attached via the first main surface to the sensing tip (101) perpendicularly relative to the measurement direction for receiving and holding a liquid droplet (111) as attached to the second main surface; the droplet holding plate comprising an electrically conductive surface layer (115), the first and the second main surfaces and the peripheral edge surface being defined by the surface layer.

Abstract: The present disclosure generally relates to novel compounds as a fatty acid synthase inhibitor useful for the treatment of infection diseases, cancers, or metabolic diseases that malfunction of fatty acid synthase is involved. In particular this present invention directs to malonyl-coenzyme A (CoA) mimetics and methods of use thereof. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using compounds disclosed herein.

Abstract: Disclosed are an image encoding/decoding method and apparatus. The method and apparatus select at least one reference pixel line from among multiple reference pixel lines and derive a predicted value of a pixel within a current block by using the value of at least one pixel within the selected reference pixel line(s). Alternatively, the method and apparatus derive an intra prediction mode of a reconstructed pixel region on the basis of a reference pixel region of at least one reconstructed pixel region, derive an intra prediction mode of a current block on the basis of the derived intra prediction mode of the reconstructed pixel region, obtain an intra prediction block of the current block by using the derived intra prediction mode, and reconstruct the current block by summing the obtained intra prediction block and a residual block of the current block.

Abstract: Embodiments described herein improve fuel economy by controlling a vehicle powertrain based on a predicted vehicle velocity. The vehicle velocity is predicted based on vehicle-to-vehicle data when a prediction horizon is a longer prediction horizon and the vehicle velocity is predicted based on historical drive cycle data when the prediction horizon is a shorter prediction horizon. A time duration of the shorter prediction horizon is shorter than the time duration of the longer prediction horizon. A plurality of drive cycles are established for both the longer and the shorter prediction horizons using a neural network. A shorter prediction horizon drive cycle uses nonlinear autoregressive exogenous model neural networks and the longer prediction horizon drive cycle uses two layer feedforward neural networks. The predicted vehicle velocity is determined from a similar drive cycle of the plurality of drive cycles of either the shorter and/or the longer prediction horizon drive cycles.

Abstract: Biodynamic imaging (BDI) performs Doppler spectroscopy of intracellular motion in living samples. The present disclosure describes novel methods and systems to perform: 1) BDI of living 3D tissue culture exposed to bacteria; 2) BDI of living biopsies exposed to bacteria; 3) BDI of infected tissues responding to antibiotics. A novel new element is the use of immortalized cancer cells to generate tissues that act as “biosensors” or “reporters” of bacterial infection, for cells as found directly in aqueous samples and cells that have been concentrated through filtration, centrifugation or a combination while maintaining them in a viable form. Pathogenicity is assessed through the spectral Doppler signatures of the changes in tissue dynamics induced by the bacteria.

Abstract: The present invention provides novel compounds of Formula (I?) and (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for killing a microorganism (e.g., bacteria, fungi, viruses, protozoa, or multicellular parasites), the prevention and/or treatment of infectious diseases (e.g., infections by microorganisms, bacterial infection, cystic fibrosis infection, foreign body infection, urinary tract infection (UTI), or infections leading to biofilms), controlling and/or eradicating biofilms (e.g., bacterial biofilms), preventing biofilm formation, sterilizing a surface, and/or eradicating persister cells (e.g., in a subject in need thereof or in a subject involving a biofilm).

Abstract: A microfluidic device may include a microstructure formed in a substrate, the microstructure including a primary channel with a first end and a second end, and a plurality of chambers that open to the primary channel. At least two openings coupled to the first end of the primary channel may be used to load at least two fluid streams into the device through the first end of the primary channel to flow along the primary channel from the first end to the second end into the plurality of chambers, each chamber of the plurality of chambers having a volume less than 100 nanoliters and connected by a vent to a secondary channel in the micro structure, a width of the vent configured to enable a gas to escape from the chamber to the secondary channel while inhibiting the flow of said at least first and second fluid streams into the secondary channel.

Abstract: A laser irradiation device for irradiating laser to a tissue includes: a decrease form determination unit configured to determine a decrease form of laser power according to a laser irradiation time; a decrease rate determination unit configured to determine a decrease rate of the determined decrease form; a laser light source unit configured to emit laser in the determined decrease form and the determined decrease rate; and a laser irradiation unit configured to receive laser emitted from the laser light source unit and irradiate the received laser. A constant photoreaction can be induced by constantly maintaining a temperature in a site to be irradiated with laser.

Abstract: The application discloses multimeric assemblies including multiple oligomeric substructures, where each oligomeric substructure includes multiple proteins that self-interact around at least one axis of rotational symmetry, where each protein includes one or more polypeptide-polypeptide interface (“O interface”); and one or more polypeptide domain that is capable of effecting membrane scission and release of an enveloped multimeric assembly from a cell by recruiting the ESCRT machinery to the site of budding by binding to one or more proteins in the eukaryotic ESCRT complex (“L domain”); and where the multimeric assembly includes one or more subunits comprising one or more polypeptide domain that is capable of interacting with a lipid bilayer (“M domain”), as well as membrane-enveloped versions of the multimeric assemblies.

Abstract: A photodetector selection apparatus and method and a scattering coefficient measurement apparatus and method are provided. The photodetector selection apparatus for measuring a scattering coefficient may include: a light source configured to emit light to a subject; a photodetector array configured to detect the light that is reflected or scattered from the subject and measure a light intensity of the detected light; and a processor configured to select at least one photodetector from a plurality of photodetectors of the photodetector array, based on a change in the measured light intensity of each of the plurality of photodetectors according to a change in a scattering coefficient of the subject, and determine the scattering coefficient of the subject based on the light intensity that is measured by the selected at least one photodetector.

Abstract: A method of duplicating texture and pattern of a natural material using a low temperature embossing process is provided. More particularly, in the method of duplicating texture and pattern of a natural material using a low temperature embossing process, a polymer resin having low glass transition temperature is coated on a surface of the natural material and then low temperature embossing process is performed thereon at a specific temperature and a specific pressure to duplicate a distinct texture and a fine pattern of the natural material as they are, thereby improving luxurious and aesthetic properties and achieving a large area and mass production, such that it may be applied to interior and exterior materials of a car, a case of a cellular phone and a laptop, home appliances, or the like.

Abstract: A zero-power digital chemical analyzer can include a chemically-selective percolation switch. The chemically selected percolation switch can include a positive electrode and a negative electrode separated from the positive electrode by a gap. A binding agent can be located at binding sites in the gap. The binding agent can be selective for binding to a target chemical compound. The binding sites can be distributed in the gap so that target chemical molecules binding to the binding sites can form an electrically conductive pathway via a natural percolation phenomenon between the electrodes when the ambient concentration of the target chemical compound reaches a threshold concentration.

Abstract: The invention provides modified griffithsin polypeptides comprising the amino acid sequence of SEQ ID NO: 1, as well as corresponding nucleic acids, vectors, cells, fusion proteins, constructs, conjugates, and methods of inhibiting viral infection.

Abstract: Disclosed are systems and methods for automated monitoring of the size, area or boundary of chronic wound images. The disclosure includes use of a probability map that measures the likelihood of wound pixels belonging to granulation, slough or eschar, which can then be segmented using any standard segmentation techniques. Measurement of the wound size, area or boundary occurs automatically and without user input related to outlining, filling in, or making measurement lines over the image on a display.

Abstract: A power semiconductor device includes a silicon carbide substrate and at least a first layer or region formed above the substrate. The silicon carbide substrate has a pattern of pits formed thereon. The device further comprising an ohmic metal disposed at least in the pits to form low-resistance ohmic contacts.

Abstract: Described are polypeptide analogs of parathyroid hormone (PTH) that include at least two non-adjacent ?-amino acid residues in place of a naturally occurring ?-amino acid residues. Also described are pharmaceutical compositions useful for treating hypoparathyroidism that contain the analogs and methods of using the analogs to treat hypoparathyroidism.

Abstract: The present invention relates to compounds and formulations derived from traditional Chinese medicine for use for the treatment and/or mediation of food allergies, in particular peanut allergies in humans by altering the activity and/or production of IgE.

Abstract: Provided are a super water repellent polymer hierarchical structure, a heat exchanger having super water repellency, and a manufacturing method thereof A super water repellent polymer hierarchical structure can be simply and repeatedly manufactured by using only a method for utilizing a super water repellent hierarchical structure and mechanically molding a polymer material thereon. In addition, a heat exchanger having super water repellency can be provided by providing super water repellency on the fin surface of a heat exchanger by using a dip method and vacuum drying.