Patents Assigned to Foundation
  • Patent number: 10414664
    Abstract: A process of producing a zeotype material having a zeolite-type framework. The process includes providing a zeolite having a framework, dealuminating the zeolite to remove aluminum atoms therefrom to produce a dealuminated framework comprising a plurality of vacancy sites, contacting the dealuminated framework with dichloromethane and a precursor comprising heteroatoms, and then heating the dealuminated framework, the dichloromethane, and the precursor under reflux conditions to incorporate the heteroatoms into at least some of the plurality of vacancy sites in the dealuminated framework to produce a zeotype material having a zeolite-type framework comprising the heteroatoms. In addition, a process is provided for producing a stannosilicate comprising a zeolite-type framework comprising Sn heteroatoms incorporated therein which form Sn sites in the zeolite-type framework each having an open configuration or a closed configuration.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: September 17, 2019
    Assignee: Purdue Research Foundation
    Inventors: Rajamani P. Gounder, Juan Carlos Vega-Vila, James William Harris
  • Patent number: 10414759
    Abstract: Series of 2-phenyl-4-methylthiazole analogs are disclosed as potential therapeutic agents for the treatment of bacterial infections, especially methicillin-resistant Straphylococcus aureus (MRSA) related infections. A method for the treatment of MRSA-related infections is also claimed.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: September 17, 2019
    Assignee: Purdue Research Foundation
    Inventors: Mark S. Cushman, Abdelrahman S. Mayhoub, Mohamed Seleem
  • Patent number: 10416896
    Abstract: A memory module includes a memory device, a command/address buffering device, and a processing data buffer. The memory device includes a memory cell array, a first set of input/output terminals, each terminal configured to receive first command/address bits, and a second set of input/output terminals, each terminal configured to receive both data bits and second command/address bits. The command/address buffering device is configured to output the first command/address bits to the first set of input/output terminals. The processing data buffer is configured to output the data bits and second command/address bits to the second set of input/output terminals. The memory device is configured such that the first command/address bits, second command/address bits, and data bits are all used to access the memory cell array.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: September 17, 2019
    Assignees: Samsung Electronics Co., Ltd., SNU R&DB Foundation, Wisconsin Alumni Research Foundation
    Inventors: Seong-Il O, Nam Sung Kim, Young-Hoon Son, Chan-Kyung Kim, Ho-Young Song, Jung Ho Ahn, Sang-Joon Hwang
  • Patent number: 10415053
    Abstract: Method of increasing resistance to a pathogen or a pest in a plant comprising introducing into the plant and expressing therein a polynucleotide comprising a nucleotide sequence encoding a Qua-Quine Starch (QQS) polypeptide; method of producing a plant with increased resistance to a pathogen or a pest comprising crossing a plant obtained in accordance with the above method with a second plant to produce progeny plants and selecting progeny plants with increased resistance to a pathogen or a pest; a plant with increased resistance to a pathogen or a pest; a seed of the plant; a hybrid of the plant; and a seed of the hybrid plant.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: September 17, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ling Li, Eve Syrkin Wurtele
  • Patent number: 10416158
    Abstract: The present application discloses proteins or peptides and methods of using such proteins or peptides to evaluate the immune status of a patient. In one embodiment, proteins or peptides may be used to detect endogenous calnexin specific CD4 T cells. In one preferred embodiment, the proteins or peptides may comprise peptide-MHCII tetramers (pMHC tetramers).
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: September 17, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Bruce Steven Klein, Marcel Wuethrich
  • Patent number: 10413606
    Abstract: This document provides methods and materials for treating cancer (e.g., skin cancer) with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: September 17, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Svetomir N. Markovic, Wendy K. Nevala
  • Patent number: 10414674
    Abstract: Bismuth-based, chloride-storage electrodes and rechargeable electrochemical cells incorporating the chloride-storage electrodes are provided. Also provided are methods for making the electrodes and methods for using the electrochemical cells to remove chloride ions from a sample. The chloride-storage electrodes, which are composed of bismuth metal, can store chloride ions in their bulk by forming BiOCl via an oxidation reaction with bismuth in the presence of an oxygen source.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: September 17, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Kyoung-Shin Choi, Dohwan Nam
  • Patent number: 10413435
    Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. The indwelling guide wire are configured to receive the access sheaths. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate catheterization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: September 17, 2019
    Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLC
    Inventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
  • Patent number: 10413383
    Abstract: A multi-diameter drill bit for implant bed preparation is provided. The drill bit has a drill shank that can be coupled with a driving tool to transfer drilling torques and forces to a drill body distal to the drill shank and a drill tip distal to the drill body. The drill body is divided into a first cylindrical portion having a first diameter and a second cylindrical portion having a second diameter. The drill tip is connected to the first cylindrical portion of the drill body and defines multiple first land areas and multiple cutting lips each at least partially bordering a respective first land areas. The second diameter is greater than the first diameter to define a plurality of faces of second lands at the interface between the first cylindrical portion and the second cylindrical portion, for reducing friction between the drill bit and surrounding bone tissue.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: September 17, 2019
    Assignee: The Research Foundation for The State University of New York
    Inventors: Marcus Abboud, Sihana Hana Rugova
  • Patent number: 10416149
    Abstract: Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: September 17, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Ravinder J. Singh, Robert L. Taylor, Stefan K. G. Grebe
  • Patent number: 10417793
    Abstract: A system and method for reconstructing an image of a subject includes acquiring a reference dataset and reconstructing a prior image of the subject from the reference dataset and selecting at least a portion of the prior image that corresponds to a portion of the prior image of the subject that is free of artifacts. The method also includes acquiring a medical imaging dataset of the subject, performing a vertical comparison of the medical imaging dataset and the reference dataset to create a data inconsistency metric, and repeating the preceding steps to create a plurality of data inconsistency metrics. The method further includes performing a horizontal comparison of the data inconsistency metrics to identify inconsistent data, compensating for the inconsistent data, and reconstructing an image of the subject with reduced artifacts compared to the prior image.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: September 17, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Guang-Hong Chen
  • Patent number: 10415095
    Abstract: The invention pertains to increased LINC00473 as an indicator of a cancer involving loss or reduction in LKB1 function. LINC00473 is also provided as a therapeutic target for treating a cancer involving loss or reduction in LKB1 function. The invention provides a method of identifying a subject as having a cancer involving loss or reduction in LKB1 function based on the level of LINC00473 in the test sample obtained from the subject and administering an effective amount of a LINC00473 inhibitor to the subject to treat the cancer. The LINC00473 inhibitor can be a small-inhibitory RNA, short hairpin RNA, bifunctional RNA, antisense oligonucleotide, ribozyme, deoxyribozyme, aptamer or small molecule inhibitor. A pharmaceutical composition comprising a LINC00473 inhibitor is also provided for the treatment of a cancer involving loss or reduction in LKB1 function.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: September 17, 2019
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Lizi Wu, Zirong Chen
  • Patent number: 10413934
    Abstract: Methods of machining a body to produce a chip are provided wherein the body is formed of a material and in a state such that the material exhibits sinuous flow during a machining operation. The methods include providing a layer located on a surface of the body, and machining the body by causing engagement between a cutting tool and the body in a contact region below an area of the surface having the coating layer thereon and moving the cutting tool relative to the body to produce the chip having the layer thereon. The layer reduces sinuous flow in the material of the body and the chip is formed primarily by laminar flow.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: September 17, 2019
    Assignee: Purdue Research Foundation
    Inventors: Ho Yeung, Koushik Viswanathan, Walter Dale Compton, Srinivasan Chandrasekar
  • Patent number: 10413575
    Abstract: The composition according to the present invention, which comprises Lactococcus chungangensis as an active ingredient, has excellent effects of preventing or treating inflammatory diseases, inhibiting the secretion of nitric oxide and prostaglandin E2, which are major inflammatory factors, and inhibiting the secretion of ?-hexosaminidase and histamine, which are major factors related to allergies, and also significantly suppressing the production of skin disease-related cytokines and chemokines. Such effects are at the same level as those of conventional skin disease therapeutic agents (tacrolimus), and thus the composition can be used as a preventive or therapeutic agent against inflammatory diseases. In addition, the composition according to the present invention exhibits an antibacterial activity against Staphylococcus aureus, which is a microorganism inducing a secondary infection of atopic dermatitis and the like, and thus can be used in preventing or treating a bacterial infection.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: September 17, 2019
    Assignee: Chung-Ang University Industry-Academic Cooperation Foundation
    Inventors: Won Yong Kim, Woo Jin Choi
  • Patent number: 10416144
    Abstract: Methods for detecting biomarkers of inflammation, infection, and/or bacterial activity in dairy production, which indicate issues with the milk itself or issues related to the health of the cow. The methods generally comprise contacting a milk sample with a nanoplatform assembly to create an assay solution, and detecting spectral changes in the assay solution that are triggered by enzymatic activity (when present) in the sample. The nanoplatform assembly comprises a first particle, a second particle, and a linkage therebetween, wherein the linkage comprises a protease consensus sequence (the sequence of amino acids cleaved by the protease), or an ester linkage (cleaved by a protease or lipase). A plurality of second particles can also be linked to the first particle. Test strips are also described, which undergo a visual color change in the presence of the target enzyme in the milk sample.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: September 17, 2019
    Assignee: Kansas State University Research Foundation
    Inventors: Deryl L. Troyer, Stefan H. Bossmann, Aruni P. Malalasekera, Thilani N. Samarakoon, Hongwang Wang, Madumali Kalubowilage
  • Patent number: 10414710
    Abstract: A method for preparing bio adipic acid includes steps of (a) preparing a glucaric acid potassium salt by mixing and reacting glucose, nitric acid (HNO3), sodium nitrite (NaNO2) and potassium hydroxide (KOH), (b) preparing glucamide from the glucaric acid potassium salt prepared in the step (a), (c) preparing 2,4-hexadiene diamide by performing a deoxydehydration reaction on the glucamide prepared in the step (b), (d) preparing adipamide by introducing the 2,4-hexadiene diamide prepared in the step (c), hydrogen and a hydrogenation catalyst to a reactor and performing a hydrogenation reaction, and (e) preparing adipic acid by introducing the adipamide prepared in the step (d) and an aqueous hydrochloric acid solution to a reactor and then performing a hydrolysis reaction at a specific temperature.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: September 17, 2019
    Assignees: Hyundai Motor Company, Kia Motors Corporation, Seoul National University R&DB Foundation
    Inventors: Chae-Hwan Hong, Ha-Eun Jeong, Na-Kyong Yun, Sung-Wan Jeon, So-Hyun Kwon, Na-Ra Shin, So-Jeong Moon, Young-Gyu Kim
  • Patent number: 10418304
    Abstract: Ion implantation can be used to define a thermal dissipation path that allows for better thermal isolation between devices in close proximity on a microelectronics chip, thus providing a means for higher device density combined with better performance.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: September 17, 2019
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, University of Virginia Patent Foundation
    Inventors: Thomas Edwin Beechem, III, Khalid Mikhiel Hattar, Jon Ihlefeld, Edward S. Piekos, Douglas L. Medlin, Luke Yates, Patrick E. Hopkins
  • Patent number: 10414805
    Abstract: The invention is directed to MtrE peptides and their use in gonorrhea vaccines.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: September 17, 2019
    Assignee: The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: Ann Jerse, Amanda DeRocco
  • Patent number: 10413892
    Abstract: A catalyst including: neodymium; sodium; and a ligand, which is a compound expressed by Structural Formula (1) below, wherein the neodymium and the ligand form a complex at a molar ratio of 1:2 (neodymium:ligand):
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 17, 2019
    Assignee: Microbial Chemistry Research Foundation
    Inventors: Masakatsu Shibasaki, Naoya Kumagai, Akihito Nonoyama, Kazuki Hashimoto, Akira Saito
  • Patent number: 10416423
    Abstract: A catadioptric telescope is a modified version of a conventional Maksutov-Cassegrain optical telescope. In accordance with the invention, the reflecting surfaces of the primary mirror and the secondary spot mirror are on the second surfaces of the primary mirror and correcting lens, respectively. In further accordance with the invention, two of these telescopes can be joined together to form a binocular telescope array. The array can be easily customized to suit different remote sensing/satellite applications.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: September 17, 2019
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Bo Zhao, Rafael Guzman