Abstract: A vehicle includes a body providing structural support and defining a fuselage perimeter and including a plurality of bands, a plurality of antennas integrated into the plurality of bands, and a transceiver operatively connected to each of the plurality of antennas. The transceiver is configured to power selected sub-sets of the plurality of antennas to generate a directional antenna beam.
Type:
Grant
Filed:
May 19, 2015
Date of Patent:
May 28, 2019
Assignees:
University of North Dakota, NDSU Research Foundation
Abstract: Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
Type:
Grant
Filed:
December 15, 2014
Date of Patent:
May 28, 2019
Assignees:
Medtronic, Inc., Mayo Foundation for Medical Education and Research
Inventors:
James Skakoon, Robert Wharen, Matthew Solar, Kari Parmer, Rudy A. Mazzocchi, John David, Frank Murdock, David Hatcher, Thomas I. Miller, Timothy Parmer, Charles Truwit
Abstract: The present disclosure provides compounds effective in increasing mucociliary clearance in a subject. In one embodiment, the compounds are of the general formula I. The present disclosure further shows that such compounds are effective in increasing activation of the CFTR, thereby increasing mucociliary clearance in the subject. The present disclosure further shows that such compounds are effective in increasing the depth of ASL, thereby increasing mucociliary clearance in the subject. In one embodiment of each of the foregoing, the subject is free from congenital or genetic defect in the cellular mucociliary clearance apparatus and/or acquired abnormality in the cellular mucociliary clearance apparatus.
Abstract: The present invention provides compositions and methods for identifying subjects suffering from dry eye that can be treated by topical administration of a composition comprising lacritin or a bioactive fragment thereof. The application discloses in part that a ˜90 KDa deglycanated form of syndecan-1 is abundant in tears of normal individuals but not individuals suffering from dry eye, whereas a ˜25 kDa syndecan-1 fragment is detectable in dry, but no normal tears.
Type:
Grant
Filed:
March 11, 2015
Date of Patent:
May 28, 2019
Assignee:
University of Virginia Patent Foundation
Abstract: The present invention relates to an antibacterial and fungicidal peptide in which a lysine and tryptophan dipeptide is repeated. More specifically, the antibacterial and fungicidal peptide of the present invention, in which lysine and tryptophan dipeptide is repeated four times, shows excellent antibacterial activities with respect to gram-positive bacteria, gram-negative bacteria and antibiotic-resistant strains by affecting the inner membrane of harmful microorganisms, has remarkable fungicidal activities with respect to pathogenic fungi and antibiotic-resistant fungi, and shows little cytotoxicity, and thus can be useful for a pharmaceutical composition, a cosmetic composition, agricultural chemicals, a food preservative, a cosmetic preservative, and a pharmaceutical preservative.
Type:
Grant
Filed:
December 6, 2017
Date of Patent:
May 28, 2019
Assignee:
Industry-Academic Cooperation Foundation, Chosun University
Abstract: A remotely activatable capsule. The capsule includes a housing that can be swallowed by a subject, an electrical energy reservoir having a first terminal and a second terminal positioned in the housing, a remotely activatable switch positioned in the housing and configured to be remotely activated, and a function-specific mechanism positioned in the housing and electrically coupled to the remotely activatable switch and to the electrical energy reservoir and configured to perform a function when the remotely activatable switch is activated.
Abstract: The present disclosure relates to a contact sensitive device and a contact sensitive device according to an exemplary embodiment of the present disclosure includes a base film, a first electrode, a second electrode, a third electrode, and a thermochromic layer. A protruding pattern is disposed on the base film. The first electrode and the second electrode are disposed on the base film and are spaced apart from each other with the protruding pattern therebetween. The third electrode is in contact with the protruding pattern. The thermochromic layer is disposed on the third electrode.
Type:
Grant
Filed:
January 16, 2018
Date of Patent:
May 28, 2019
Assignees:
LG Display Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
WooYoung Shim, HanSaem Kang, KiSeok Chang, WookSung Kim, SungPil Ryu, GwangMook Kim, SungJun Cho, JaeMin Myoung
Abstract: An example method of forming a deterministic thin film from a crystal substrate is described herein. The method can include implanting ions into a surface of the crystal substrate to form a thin film crystal layer, and bonding the crystal substrate and a handle substrate to form a bilayer bonding interface between the crystal substrate and the handle substrate. The method can also include exfoliating the thin film crystal layer from the crystal substrate, patterning the thin film crystal layer to define a deterministic thin film, etching one or more trenches in the thin film crystal layer, etching the bilayer bonding interface via the one or more trenches, and releasing the deterministic thin film from the handle substrate.
Abstract: Sodium negative active material may have a metal phosphate having a uniform size distribution structures to graphene surface. The negative active material is a metal or a metal oxide precursor in a graphite dispersion solution; And the addition of phosphate, and then applying a microwave, can be produced by heat treatment.
Type:
Grant
Filed:
October 19, 2016
Date of Patent:
May 28, 2019
Assignee:
University-Industry Foundation, Yonsei University
Inventors:
Kwang Bum Kim, Ha Kyung Roh, Hyun Kyung Kim, Myeong Seong Kim
Abstract: Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic.
Type:
Grant
Filed:
October 5, 2016
Date of Patent:
May 28, 2019
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: An analog-digital converter may include: an analog-digital converter comprising: a ramp signal selection unit suitable for receiving ramp signals having different offsets, and sequentially selecting one of the ramp signals according to a preset order; a comparison unit suitable for comparing the magnitudes of the selected ramp signal with a pixel signal, and outputting a comparison signal according to the comparison result; and a counting unit suitable for counting the number of clocks of a clock signal until the comparison signal transitions, and outputting a count signal based on the count when the comparison signal transitions.
Type:
Grant
Filed:
May 25, 2017
Date of Patent:
May 28, 2019
Assignees:
SK hynix Inc., Industry-University Cooperation Foundation Hanyang University
Inventors:
Sang Dong Yoo, Min Kyu Kim, Jun Bo Shim
Abstract: A method for sequence-specifically detecting a nucleic acid molecule. The method requires: a) contacting in an absence of an electric field, a mixture of nucleic acid molecules with a base pairing hybridizing molecule (BPHM) having a sequence of interest in a first solution and obtaining a hybrid consisting the nucleic acid molecule and the BPHM; b) introducing the first solution from step (a) into an ITP system, the ITP system comprises a second solution of high effective mobility leading electrolyte (LE) ions and a third solution of low effective mobility trailing electrolyte (TE); and c) applying the electric field across the second solution and the third solution. The hybrid focus at the sharp LE-TE interface in the ITP system. The TE has a higher mobility than the BPHM and the TE has a lower mobility than the hybrid. Sequence-specifically the detecting nucleic acid molecule by a signal from a label.
Type:
Grant
Filed:
March 27, 2017
Date of Patent:
May 28, 2019
Assignee:
Technion Research and Development Foundation Limited
Abstract: Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.
Type:
Grant
Filed:
December 2, 2016
Date of Patent:
May 28, 2019
Assignees:
University of Florida Research Foundation, Inc., Alachua County Public Works
Inventors:
Timothy Townsend, Ronald Bishop, David Wood, James Lloyd
Abstract: Described herein are fluid-manipulation-based devices. Fluid manipulations as described herein can be configured to perform assays on biological samples. In an embodiment, the device includes a reaction chamber, which can includes an integrated sample isolation module, a cell lysis module, a biological target purification module, and an assay mixing module, which can include a microbead with a capture molecule coupled thereto and a nanoparticle having a probe molecule coupled thereto via a label, which can be a spectroscopic label. In an embodiment, the capture and probe molecules can be configured to be coupled together via a biological target to form a biological molecule bead complex. Devices and methods as described herein can manipulate and analyze nanoliter volumes of fluid, microliter volumes of fluid, milliliter volumes of fluid, or greater. Embodiments of the present disclosure can enable random biological assays and rapid, simultaneous analysis of multiple biological samples.
Type:
Grant
Filed:
November 18, 2016
Date of Patent:
May 28, 2019
Assignee:
University of Florida Research Foundation, Inc.
Abstract: A speech intelligibility system. Embodiments comprise a talker unit, a listener unit and an earpiece. The talker unit includes a microphone to receive audible speech content and to produce electrical signals representative of the speech content, and a transmitter coupled to the microphone to produce wireless transmissions containing the speech content. The listener unit includes a receiver to receive the wireless transmissions and to produce electrical signals representative of the speech content. At least one of the talker unit and the listener unit includes an amplifier to amplify spectral components of the speech content within a frequency range having a lower end between about 800 Hz and 1,700 Hz and an upper end between about 7,000 Hz and 11,000 Hz. The earpiece is coupled to the listener unit and includes a speaker to produce audible speech content having the amplified spectral components and a tube to direct the audible speech content from the speaker toward a user's ear canal.
Type:
Grant
Filed:
June 29, 2018
Date of Patent:
May 28, 2019
Assignees:
Mayo Foundation for Medical Education and Research, Etymotic Research, Inc.
Inventors:
Michael J. Cevette, Jan Stepanek, Mead C. Killion, Charles J. Aldous
Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A reception method for an electronic device of the present disclosure comprises the steps of: receiving, from a transmission device, first location information including information on the coverage area of the transmission device; generating second location information using the first location information and location information of the electronic device; and determining location information of the transmission device using the second location information and information on the coverage area of the electronic device.
Type:
Grant
Filed:
June 8, 2016
Date of Patent:
May 28, 2019
Assignees:
Samsung Electronics Co., Ltd., Research & Business Foundation Sungkyunkwan University
Inventors:
Hyunseok Ryu, Sang-Hyo Kim, Jong-Hwan Kim, Seung-Hoon Park, Peng Xue, Kyung-Min Lee, Min Jang
Abstract: Methods, kits, and compositions of matter relating to poly(UG) polymerases are disclosed. In one embodiment, a method includes: contacting an RNA substrate with a poly(UG) polymerase; and allowing the poly(UG) polymerase to add a poly(UG) sequence to the end of the RNA substrate by retaining contact between the RNA substrate and the poly(UG) polymerase for a period of time from about 1 second to about 28 days. The poly(UG) polymerase can be Caenorhabditis elegans RDE-3.
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
Type:
Grant
Filed:
March 26, 2015
Date of Patent:
May 28, 2019
Assignees:
Mayo Foundation for Medical Education and Research, Exact Sciences Development Company, LLC
Inventors:
David Alan Ahlquist, William Russell Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Abstract: This document provides butyrylcholinesterases having an enhanced ability to hydrolyze acyl ghrelin as well as nucleic acids encoding such butyrylcholinesterases. This document also provides methods and materials for treating obesity and/or aggression. For example, methods for administering a nucleic acid encoding a wild-type or mutant butyrylcholinesterase having the ability to hydrolyze acyl ghrelin to a mammal under conditions wherein the level of acyl ghrelin within the mammal is reduced, under conditions wherein the rate of body weight gain of the mammal is reduced, under conditions wherein the mammal's level of aggression is reduced, and/or under conditions wherein the mammal's rate of developing stress-induced tissue damage are provided.
Type:
Grant
Filed:
April 29, 2015
Date of Patent:
May 28, 2019
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Liyi Geng, Ping Chen, William S. Brimijoin, Yang Gao
Abstract: The present disclosure relates to a pre-5th-generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4th-generation (4G) communication system such as a long term evolution (LTE). A method of a receiving apparatus in a communication system supporting a low density parity check (LDPC) code is provided. The method includes deactivating variable nodes of which absolute values of log likelihood ratio (LLR) values are greater than or equal to a first threshold value; changing LLR values of variable nodes of which absolute values of LLR values are less than a second threshold value among variable nodes other than the deactivated variable nodes to a preset value, and detecting LLR values of check nodes based on LLR values of the variable nodes other than the deactivated variable nodes.
Type:
Grant
Filed:
March 10, 2017
Date of Patent:
May 28, 2019
Assignees:
Samsung Electronics Co., Ltd., Korea University Research and Business Foundation
Inventors:
Myeong-Woo Lee, Young-Kil Suh, Jun Heo, Jong-Hyun Baik