Patents Assigned to Foundation
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Patent number: 10246724Abstract: Various embodiments of the present invention pertain to methods for biological production of hydrogen. More specifically, embodiments of the present invention pertain to a modular energy system and related methods for producing hydrogen using organic waste as a feed stock.Type: GrantFiled: November 21, 2016Date of Patent: April 2, 2019Assignee: Purdue Research FoundationInventors: Robert Kramer, Libbie S. Pelter, John A. Patterson
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Patent number: 10248666Abstract: A method of creating a hierarchical dictionary comprises, with a processor, extracting a number of symbols from a first image, constructing a number of refinement dictionary entries based on the symbols, the refinement dictionary entries forming a refinement dictionary, grouping a number of the refinement dictionary entries into clusters to form a number of refinement dictionary entry clusters, and constructing a number of direct dictionary entries for each of the refinement dictionary entry clusters, the direct dictionary entries forming a direct dictionary.Type: GrantFiled: April 30, 2013Date of Patent: April 2, 2019Assignees: Hewlett-Packard Development Company, L.P., Purdue Research FoundationInventors: Dejan Depalov, Peter Bauer, Yandong Guo, Jay Allebach, Charles A. Bouman
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Patent number: 10247177Abstract: Positive displacement machines and methods therefor capable of increasing a load-carrying capacity of a piston-cylinder lubrication interface of positive displacement machines having a cylinder block, a cylindrical bore defined in the cylinder block, a piston reciprocably disposed within the cylindrical bore, and a working fluid within the piston-cylinder lubrication interface to provide a load-bearing function between the piston and the bore wall of the cylinder bore. The method includes providing at least one circumferential groove on a bore wall of the cylindrical bore within the piston-cylinder lubrication interface having an opening facing the piston and that is in fluidic communication with the piston-cylinder lubrication interface so as to contain a portion of the working fluid, and operating the positive displacement machine such that the working fluid enters the cylindrical groove and promotes hydrostatic balancing of pressure of the working fluid within the piston-cylinder lubrication interface.Type: GrantFiled: July 12, 2016Date of Patent: April 2, 2019Assignee: Purdue Research FoundationInventors: Monika Marianne Ivantysynova, Meike H. Ernst
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Patent number: 10248675Abstract: A circuit element of a multi-dimensional dynamic adaptive neural network array (DANNA) may comprise a neuron/synapse select input functional to select the circuit element to function as one of a neuron and a synapse. In one embodiment of a DANNA array of such circuit elements, (wherein a circuit element may be digital), a destination neuron may be connected to a first neuron by a first synapse in one dimension a second destination neuron may be connected to the first neuron by a second synapse in a second dimension to form linked columns and rows of neuron/synapse circuit elements. In one embodiment, the rows and columns of circuit elements have read registers that are linked together by signal lines and clocked and controlled so as to output columnar data to an output register when a neuron/synapse data value is stored in the read register.Type: GrantFiled: October 14, 2014Date of Patent: April 2, 2019Assignee: University of Tennessee Research FoundationInventors: J. Douglas Birdwell, Mark E. Dean, Catherine Schuman
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Publication number: 20190093106Abstract: The application discloses compositions and methods for preventing and treating diabetic retinopathy. It is disclosed herein that an inhibitor of microRNA-let-7b administered to the eye of a subject in need thereof is useful for preventing and treating several problems associated with diabetic retinopathy and plays a role in vasculature stabilization, increasing retinal thickness, reducing retinal capillary dropout, diminishing microvascular leakage, preventing or treating hyperproliferation of microvascular cells, and stabilizing aberrant neovascularization. The invention includes the use of various kinds of inhibitors of microRNA-let-7b, including, but not limited to, an antagomir of miRNA-let-7b. A useful compound of the invention can be administered into the eye, including intravitreally. A useful antagomir is Dy547-mA(*)mA(*)mCmCmAmCmAmCmAmAmCmCmUmAmCmUmAmCmCmU(*) mC(*)mA (*)(3?-Chl).Type: ApplicationFiled: October 6, 2016Publication date: March 28, 2019Applicant: University of Virginia Patent FoundationInventors: Bijan K. Dey, Paul Andrew Yates
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Publication number: 20190093111Abstract: Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject.Type: ApplicationFiled: March 1, 2017Publication date: March 28, 2019Applicants: University of Florida Research Foundation, Incorporated, The Trustees of the University of PennsylvaniaInventors: Alfred S. Lewin, William W. Hauswirth, MIchael T. Massengill, William Beltran, Gustavo D. Aguirre, Artur Cideciyan, Samuel Jacovson
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Publication number: 20190097130Abstract: In a first aspect of the present disclosure, there is provided a nonvolatile memory device comprising: two electrodes; and a protein switching layer interposed between the two electrodes and including an amino acid, wherein then a voltage is applied to one of the electrodes, the amino acid chelates with an active electrode material to form a conductive filament, wherein the formation of the conductive filament allows a resistance state of the device to vary.Type: ApplicationFiled: September 20, 2018Publication date: March 28, 2019Applicant: Research & Business Foundation Sungkyunkwan UniversityInventors: Sungjoo LEE, Woo-Seok CHOE, Sung Kyu JANG
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Publication number: 20190096277Abstract: The present disclosure relates to systems and methods for measuring reading performance.Type: ApplicationFiled: September 25, 2018Publication date: March 28, 2019Applicants: Ohio State Innovation Foundation, Adaptive Sensory Technology, Inc.Inventors: Zhong-Lin Lu, Fang Hou, Deyue Yu, Peter J. Bex, Luis A. Lesmes
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Publication number: 20190090802Abstract: Disclosed is a VR (Virtual Reality) device for diagnosis of nerve disorder, system and method thereof, wherein the device comprises: a display part providing a user with a VR environment in response to an image; and a user response receiver receiving a user response relative to the image, and wherein the image includes an introduction video included with two or more characters, and a question video image provided subsequent to the introduction video to include an inquiry related to the characters, whereby a user's linguistic competence, visual ability and associative ability can be comprehensively evaluated, and more accurately grasp a degree of user's nerve disorder can be accurately grasped without being influenced by a user's academic background and age.Type: ApplicationFiled: September 14, 2018Publication date: March 28, 2019Applicants: Samsung Life Public Welfare Foundation, Korea Institute of Science and TechnologyInventors: Duk Lyul NA, Ko Woon Kim, Jong Doo Choi, Ju Hee Chin, Byung Hwa Lee, Jee Hyun Choi, Hye Joo Lee, Hyo Been Han
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Publication number: 20190094223Abstract: Provided are methods of predicting responsiveness of a subject having an inflammatory bowel disease (IBD) to a tumor necrosis factor (TNF)-alpha inhibitor, by analyzing a frequency of at least one subpopulation of immune cells in a tissue biopsy of the subject. Also provided are methods of selecting a treatment for a subject and kits for determining responsiveness of the subject to treatment with a TNF-alpha inhibitor.Type: ApplicationFiled: April 6, 2017Publication date: March 28, 2019Applicants: Technion Research & Development Foundation Limited, The Board of Trustees of the Leland Stanford Junior UniversityInventors: Shai S. SHEN-ORR, Elina STAROVETSKY, Naama MAIMON, Purvesh KHATRI, Renaud GAUJOUX, Francesco VALLANIA
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Publication number: 20190097378Abstract: A method for designing a non-circular dielectric resonator is provided. The method includes obtaining a conformal transformation coordinate of the non-circular dielectric resonator to correspond to a rectangular coordinate system of a circular dielectric resonator, mapping the obtained conformal transformation coordinate to the non-circular dielectric resonator, and setting a refractive index in the non-circular resonator and allowing an incident angle of light to satisfy a condition for total reflection in each of boundary areas in a non-circular dielectric resonator to which the conformal transformation coordinate is mapped.Type: ApplicationFiled: September 20, 2018Publication date: March 28, 2019Applicant: Kyungpook National University Industry-Academic Cooperation FoundationInventor: Muhan Choi
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Publication number: 20190092926Abstract: The surface hydrophobization of cellulose nanocrystals (CNCs) by carboxylic acids, biodiesel, or plant oils was conducted via there herein disclosed green process using an one-pot synthetic method. In the process, an aqueous lactic acid syrup served as a solvent to provide a stable and well-dispersed water suspension of CNCs and participated in esterification reactions to produce an intermediate product of polylactic acid (PLA) oligomer grafted CNCs (CNC-g-PLA). This solvent and intermediate product system allows for an in situ solvent exchange from water to lactic acid without prior drying of the CNCs and a subsequent efficient esterification reaction of CNCs with carboxylic acids or esters having a long hydrocarbon chain (FAs). Another advantage of the disclosed process is the ability to reuse the reagents in the subsequent reaction in order to reduce the production cost.Type: ApplicationFiled: February 27, 2017Publication date: March 28, 2019Applicant: Purdue Research FoundationInventors: Jeffrey Paul Youngblood, Youngman Yoo
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Publication number: 20190090554Abstract: In one embodiment, a garment having a cup portion with two cups, a body portion integrated with the cup portion, and a band are disposed on the garment such that is extends beneath the cup portions. The band is either on the body portion or adjacent the body portion. The garment also has support structures with a configuration, each following proximately a contour of the lower part of its respective cup, wherein a portion of the support structure is formed on and fixed to the band and a portion of the support structure extends on the body of the garment and is attached thereto. As such the support structure configuration is approximately arcuate. The garment also has additional control regions. The control is provided by fabric or materials that have less stretch than the body fabric from which the body of the garment is made.Type: ApplicationFiled: November 21, 2018Publication date: March 28, 2019Applicant: Cupid Foundations Inc.Inventors: Anthony Angelino, John David Blancuzzi, Lisa Ann Hand, Brenda Lee Wilson
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Publication number: 20190093180Abstract: Provided herein are a probe capable of simultaneously detecting a virus and treating virus-infected cells, a composition for detecting a virus, which comprises the probe, a composition for treating a virus, which comprises the probe, and a method of detecting a virus or treating a viral infection by using the same. According to the present disclosure, it is possible to simultaneously perform diagnosis by virus detection and treatment of virus-infected cells, and in particular, diagnosis and treatment may be simultaneously performed on various types of viruses by varying the type of molecular beacon, and thus may be usefully applied to virus diagnosis and treatment fields, which require rapid diagnosis and treatment, and the spread of viral infections may be effectively prevented. In addition, the probe of the present disclosure has excellent stability and excellent detection sensitivity, and thus enables the detection of even a very low amount of a target at the pmole level.Type: ApplicationFiled: September 26, 2018Publication date: March 28, 2019Applicants: Yonsei University Industry Foundation (Yonsei UIF), Korea University Research and Business Foundation, Sejong CampusInventors: Seung Joo HAAM, Hyun Ouk KIM, Byung Hoon KANG, Seung Min HAN, Ji Sun KI, Dae Sub SONG, Woon Sung NA, Min Joo YEOM
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Publication number: 20190093127Abstract: This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules encoding viruses, cell lines containing viral vectors, and methods for using viruses to deliver nucleic acid to cells in vitro or in vivo are provided. Methods and materials for using adenovirus vectors to induce immune responses and to treat cancer also are provided.Type: ApplicationFiled: October 8, 2018Publication date: March 28, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Michael A. Barry, Eric Weaver
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Publication number: 20190090891Abstract: The present invention relates to a calculus removing device used in medical fields and, more particularly, to a calculus removing device having a calculus crushing probe, which can simultaneously crush and remove a calculus formed inside a human body selectively using a drawing force or electricity through the calculus crushing probe, regardless of the size of the calculus.Type: ApplicationFiled: April 5, 2016Publication date: March 28, 2019Applicant: The Catholic University of Korea Industry-Academic Cooperation FoundationInventor: Hiun Suk Chae
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Publication number: 20190093075Abstract: Methods for ex vivo expansion of very small embryonic like stem cells in the absence of feeder cells are provided. In some embodiments the methods include providing a plurality of VSELs; and growing the VSELs in a culture medium that includes a histone deacetylase inhibitor, luteinizing hormone, follicle-stimulating hormone, and optionally transforming growth factor beta in an amount that is sufficient to overcome quiescence of the VSELs. Also provided are feeder cell-free cell cultures, ex vivo expanded VSELs, pharmaceutical compositions that include the disclosed ex vivo expanded VSELs, methods for overcoming quiescence in VSELs, methods for re-establishing imprinting in VSELs, method for treating injuries to tissues in subjects, methods for repopulating cell types in subjects, methods for bone marrow transplantation, methods for treating radiation exposure in subjects, and methods that relate to regenerative medicine.Type: ApplicationFiled: March 3, 2017Publication date: March 28, 2019Applicant: University of Louisville Research Foundation, Inc.Inventors: Mariusz Z. Ratajczak, Janina Ratajczak, Magdalena Kucia, Donald Miller
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Publication number: 20190090946Abstract: A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.Type: ApplicationFiled: November 20, 2018Publication date: March 28, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Samuel J. Asirvatham, Mark B. Knudson
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Publication number: 20190092885Abstract: This invention generally relates to a method for modulating interfacial wettability of a noncovalent nanoscopic monolayer or thin film. Particularly, this invention relates to a method for modulating interfacial wettability of a two-dimensional (2D) material using a molecular layer prepared from a polymerizable amphiphilic monomer having a hydrophilic head and a hydrophobic tail, wherein enhanced or decreased wettability of said 2D material is achieved by proper allocating the position of polymerizable group relative to the hydrophilic head and the hydrophobic tail.Type: ApplicationFiled: September 28, 2018Publication date: March 28, 2019Applicant: Purdue Research FoundationInventors: Shelley A. Claridge, Jae Jin Bang, Shane Richard Russell, Terry Angelo Villarreal
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Publication number: 20190097014Abstract: The present disclosure provides a multi-functional electronic device with a black phosphorous-based single channel, wherein the device comprises: a black phosphorous-based single channel layer including a horizontal arrangement of a first semiconductor region and a second semiconductor region to define a horizontal junction therebetween, wherein the second semiconductor region has a lower hole-carrier density than the first semiconductor region; a first electrode connected to the first semiconductor region; a second electrode spaced from the first electrode and connected to the second semiconductor region; an ionic gel layer disposed on the first semiconductor region; and a gate electrode for receiving a gate voltage to generate an electric field in the channel layer.Type: ApplicationFiled: July 25, 2018Publication date: March 28, 2019Applicant: Research & Business Foundation Sungkyunkwan UniversityInventors: Sungjoo LEE, Jingyuan JIA, Sumin JEON, Jin-Hong PARK